当前位置： SCI文献检索 > FERTILITY AND STERILITY期刊下所有文献 > The activity (calcium oscillator?) responsible for human oocyte activation after injection with round spermatids is associated with spermatid nuclei.

The activity (calcium oscillator?) responsible for human oocyte activation after injection with round spermatids is associated with spermatid nuclei.

Abstract：

OBJECTIVE:To compare the oocyte-activating ability of whole human round spermatids and their isolated nuclei. DESIGN:Prospective study using sibling oocytes from patients undergoing spermatid conception and intracytoplasmic sperm injection treatment cycles. SETTING:Private assisted reproduction laboratories and a university department. PATIENT(S):Couples with male infertility. INTERVENTION(S):Sibling oocytes were injected either with whole round spermatids or with their isolated nuclei, followed by artificial triggering of oocyte activation with calcium ionophore. Other sibling oocytes were injected either with isolated spermatid cytoplasm or with whole mature spermatozoa. MAIN OUTCOME MEASURE(S):Numbers of activated oocytes and cleaving embryos. RESULT(S):After oocyte activation was boosted with calcium ionophore, whole spermatids and isolated spermatid nuclei were equally effective in supporting oocyte activation and the formation of pronuclei, whereas no control oocyte was activated under the same conditions after injection of isolated spermatid cytoplasmic compartments. Cleavage rates were lower after the injection of isolated spermatid nuclei than after the injection of whole spermatids. CONCLUSION(S):The factor responsible for human oocyte activation after round spermatid injection is associated with spermatid nuclei. The requirement for the artificial trigger (calcium ionophore) suggests that this factor is identical to the male gamete activity previously characterized as calcium oscillator.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Tesarik J,Mendoza C,Greco E

doi

10.1016/s0015-0282(00)01598-3

keywords:

subject

Has Abstract

pub_date

2000-12-01 00:00:00

pages

1245-7

issue

6

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(00)01598-3

journal_volume

74

pub_type

杂志文章

相关文献

FERTILITY AND STERILITY文献大全
  • Long-acting gonadotropin hormone-releasing hormone analog used to treat uteri.

    abstract：:Because the size of leiomyomata uteri often decreases significantly after menopause, the authors elected to employ a long-acting gonadotropin hormone-releasing hormone analog (GnRH-alpha) (imbzl-D-His6-Pro9-Net-GnRH) to create a state of pseudomenopause in six patients with leiomyomata uteri diagnosed on the basis of ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)49332-5

    authors： Coddington CC,Collins RL,Shawker TH,Anderson R,Loriaux DL,Winkel CA

    更新日期：1986-05-01 00:00:00

  • Endometrial microbiota in infertile women with and without chronic endometritis as diagnosed using a quantitative and reference range-based method.

    abstract：OBJECTIVE:To systematically compare the endometrial microbiota in infertile women with and without chronic endometritis (CE), as diagnosed by a quantitative and reference range-based method. DESIGN:Case-control observational study. SETTING:University-affiliated hospital. PATIENT(S):One hundred and thirty infertile w...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2019.05.015

    authors： Liu Y,Ko EY,Wong KK,Chen X,Cheung WC,Law TS,Chung JP,Tsui SK,Li TC,Chim SS

    更新日期：2019-10-01 00:00:00

  • Role of temperature in regulation of spermatogenesis and the use of heating as a method for contraception.

    abstract：:A large body of research confirms the vulnerable nature of spermatogenesis to relatively small increases in testicular temperature. Other physical properties of electromagnetic and ultrasound waves have additive or synergistic effects to those of heat and allow disruption of spermatogenic processes at minimal tempera...

    journal_title：Fertility and sterility

    pub_type： 杂志文章,评审

    doi：10.1016/s0015-0282(16)59640-x

    authors： Kandeel FR,Swerdloff RS

    更新日期：1988-01-01 00:00:00

  • Laparoscopic management of heterotopic cesarean scar pregnancy with preservation of intrauterine gestation and delivery at term: case report.

    abstract：OBJECTIVE:To present a case of laparoscopic removal of a heterotopic cesarean scar pregnancy under ultrasound guidance. DESIGN:Case report. SETTING:Private hospital. PATIENT(S):A 34-year-old woman with heterotopic cesarean scar pregnancy. INTERVENTION(S):Laparoscopic removal of heterotopic cesarean scar pregnancy. ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2008.01.067

    authors： Demirel LC,Bodur H,Selam B,Lembet A,Ergin T

    更新日期：2009-04-01 00:00:00

  • Impact of fertility treatment on severe maternal morbidity.

    abstract：OBJECTIVE:To determine if fertility treatment is associated with increased risk of severe maternal morbidity (SMM) compared with spontaneous pregnancies. DESIGN:Retrospective cohort study. SETTING:Academic medical center. PATIENT(S):In 2012, 6,543 women delivered live births >20 weeks gestation at our center. Women ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2016.03.039

    authors： Wang ET,Ozimek JA,Greene N,Ramos L,Vyas N,Kilpatrick SJ,Pisarska MD

    更新日期：2016-08-01 00:00:00

  • Secondary hypogonadism in hemochromatosis.

    abstract：:Hemochromatosis is a rare disorder of iron storage. This report illustrates a case of hypogonadotropic-hypogonadism in a female with biopsy-proven hemochromatosis. Dynamic pituitary and gonadal testing revealed subnormal gonadotropin responses to gonadotropin-releasing hormone (GnRH) but normal ovarian reserve, as sho...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)53842-4

    authors： Meyer WR,Hutchinson-Williams KA,Jones EE,DeCherney AH

    更新日期：1990-10-01 00:00:00

  • Culture of human granulosa cells from an in vitro fertilization program: effects of extracellular matrix on morphology and cyclic adenosine 3',5' monophosphate production.

    abstract：:Human GCs obtained from patients undergoing an IVF procedure and treated with CC, hMG, and hCG, lack cAMP responsiveness to hCG stimulation in vitro. After 48 hours in culture, recovery of cAMP production was significantly higher in hCG-stimulated cells grown on dishes coated with ECM than in cells grown on uncoated d...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)49596-8

    authors： Furman A,Rotmensch S,Dor J,Venter A,Mashiach S,Vlodavsky I,Amsterdam A

    更新日期：1986-09-01 00:00:00

  • Executive summary of the Stages of Reproductive Aging Workshop + 10: addressing the unfinished agenda of staging reproductive aging.

    abstract：OBJECTIVE:The aim of this article is to summarize the recommended updates to the 2001 Stages of Reproductive Aging Workshop (STRAW) criteria. The 2011 STRAW + 10 reviewed advances in understanding of the critical changes in hypothalamic-pituitary-ovarian function that occur before and after the final menstrual period. ...

    journal_title：Fertility and sterility

    pub_type： 共识发展会议,杂志文章,实务指引

    doi：10.1016/j.fertnstert.2012.01.128

    authors： Harlow SD,Gass M,Hall JE,Lobo R,Maki P,Rebar RW,Sherman S,Sluss PM,de Villiers TJ,STRAW + 10 Collaborative Group.

    更新日期：2012-04-01 00:00:00

  • Higher aneuploidy rates of chromosomes 13, 16, and 21 in a patient with globozoospermia.

    abstract：OBJECTIVE:To analyze rates of chromosomal anomalies in a patient with globozoospermia. DESIGN:Case report. SETTING:Tertiary-care infertility clinic. PATIENT(S):A 44-year-old man with 100% globozoospermia. INTERVENTION(S):Fixation of sperms and analysis of aneuploidies and diploidies by fluorescence in situ hybridiz...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2005.01.109

    authors： Ditzel N,El-Danasouri I,Just W,Sterzik K

    更新日期：2005-07-01 00:00:00

  • Presence of the "Beaumont" protein in serum of oral contraceptive users.

    abstract：:The level of the "Beaumont" protein present in serum was measured by a population of 223 black and 76 Caucasian women with different exposures to oral contraceptives (OCs). No differences were found in the values in nonusers, past users, current users, or new users of OCs. The values were higher in black nonusers and ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：

    authors： Collins DC,Bain RP,Coan P,Macpherson RF,Blumenstein B,Hall WD

    更新日期：1983-10-01 00:00:00

  • Serum sex hormone-binding globulin levels show too much variability to be used effectively as a screening marker for insulin resistance in women with polycystic ovary syndrome.

    abstract：OBJECTIVE:To evaluate the relationship between serum sex hormone-binding globulin (SHBG) and parameters of insulin sensitivity in women with polycystic ovary syndrome (PCOS) and controls, and determine the feasibility of using SHBG levels to predict insulin resistance. DESIGN:Evaluation of a prospectively collected da...

    journal_title：Fertility and sterility

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.fertnstert.2006.02.108

    authors： Dahan MH,Goldstein J

    更新日期：2006-10-01 00:00:00

  • Biochemical, metabolic, and vascular mechanisms in menopausal hot flashes.

    abstract：OBJECTIVE:To determine if increases in core body temperature preceding most hot flashes are caused by increased metabolic rate, peripheral vasoconstriction, or central noradrenergic activation. DESIGN:Laboratory physiological study. SETTING:University medical center. PATIENT(S):Fourteen healthy, postmenopausal women...

    journal_title：Fertility and sterility

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0015-0282(98)00137-x

    authors： Freedman RR

    更新日期：1998-08-01 00:00:00

  • Blastocyst formation, pregnancy, and birth derived from human oocytes cryopreserved for 5 years.

    abstract：OBJECTIVE:To report a live birth after the transfer of a single blastocyst derived from a human oocyte cryopreserved for 5 years. DESIGN:Case report. SETTING:Private assisted reproduction center. PATIENT(S):A 39-year-old woman with tubal infertility and her partner with male-related infertility. INTERVENTION(S):Ooc...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2008.01.106

    authors： Parmegiani L,Fabbri R,Cognigni GE,Bernardi S,Pocognoli P,Filicori M

    更新日期：2008-11-01 00:00:00

  • Frozen-thawed day 5 blastocyst transfer is associated with a lower risk of ectopic pregnancy than day 3 transfer and fresh transfer.

    abstract：OBJECTIVE:To determine the ectopic pregnancy rate with fresh versus frozen-thawed embryo transfers, and factors associated with ectopic pregnancy in patients undergoing IVF-ET. DESIGN:Retrospective analysis. SETTING:Institutional IVF center. PATIENT(S):A total of 3,183 patients who received 3,340 blastocysts transfe...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2014.11.023

    authors： Fang C,Huang R,Wei LN,Jia L

    更新日期：2015-03-01 00:00:00

  • Immunocytochemistry of the estrogen receptor in spontaneous endometriosis in rhesus macaques.

    abstract：:Immunocytochemical, biochemical, and histologic analysis of endometriotic lesions and endometria from rhesus macaques with endometriosis revealed several distinctions between ectopic and eutopic endometrium. In lesions, unlike endometrium, neither the mean percentages of estrogen receptor positive (ER+) cells nor the ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：

    authors： Sternfeld MD,West NB,Brenner RM

    更新日期：1988-02-01 00:00:00

  • Cryopreservation of human embryos by vitrification or slow freezing: a systematic review and meta-analysis.

    abstract：OBJECTIVE:To examine the literature systematically in order to identify prospective comparative trials answering the following question: Is vitrification of human embryos associated with a higher postthawing survival rate as compared with slow freezing? DESIGN:Systematic review and meta-analysis. SETTING:University-b...

    journal_title：Fertility and sterility

    pub_type： 杂志文章,meta分析,评审

    doi：10.1016/j.fertnstert.2007.06.010

    authors： Loutradi KE,Kolibianakis EM,Venetis CA,Papanikolaou EG,Pados G,Bontis I,Tarlatzis BC

    更新日期：2008-07-01 00:00:00

  • Aromatase inhibitor letrozole: a novel treatment for ectopic pregnancy.

    abstract：OBJECTIVE:To study the use of the aromatase inhibitor letrozole for treatment of ectopic pregnancy compared with methotrexate. DESIGN:Nonrandomized prospective cohort study. SETTING:University hospital. PATIENT(S):A series of 42 consecutive patients with undisturbed ectopic pregnancy. INTERVENTION(S):Counseling on ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2020.04.001

    authors： Mitwally MF,Hozayen WG,Hassanin KMA,Abdalla KA,Abdalla NK

    更新日期：2020-08-01 00:00:00

  • Danazol binding to steroid receptors in human uterine endometrium.

    abstract：:To understand the mechanism of action of danazol, the binding of danazol to multiple classes of intracellular steroid binding proteins was studied in the human uterine endometrium. Danazol bound to endometrial receptors for estrogen, progesterone, and androgen and seemed to bind to endometrial intracellular corticoste...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)47840-4

    authors： Tamaya T,Wada K,Fujimoto J,Yamada T,Okada H

    更新日期：1984-05-01 00:00:00

  • Adhesion formation and interanimal variability in a laparoscopic mouse model varies with strains.

    abstract：:Adhesion formation after laparoscopic surgery was evaluated in mice of different strains. More adhesions were observed in Swiss, NMRI, and BALB/c mice, with less interanimal variability in BALB/c mice. These data point to genetics effects on adhesion formation, which open new insights in its pathogenesis and indicate ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2004.11.084

    authors： Molinas CR,Binda MM,Campo R,Koninckx PR

    更新日期：2005-06-01 00:00:00

  • Endometrial responses to three different progestins in artificial cycles: a prospective, crossover study.

    abstract：:We found that there was no significant difference in endometrial responses to vaginal or IM P. But the response was suboptimal in cycles treated with dydrogesterone, suggesting that dydrogesterone treatment is not the preferred progestin for use in artificial cycles. ...

    journal_title：Fertility and sterility

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0015-0282(16)56840-x

    authors： Li TC,Aplin JD,Warren A,Graham RA,Dockery P,Cooke ID

    更新日期：1994-07-01 00:00:00

  • Myo-inositol may improve oocyte quality in intracytoplasmic sperm injection cycles. A prospective, controlled, randomized trial.

    abstract：OBJECTIVE:To determine the effects of myo-inositol on oocyte quality in polycystic ovary syndrome (PCOS) patients undergoing intracytoplasmic sperm injection (ICSI) cycles. DESIGN:A prospective, controlled, randomized trial. SETTING:Assisted reproduction centers. PATIENT(S):Sixty infertile PCO patients undergoing ov...

    journal_title：Fertility and sterility

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.fertnstert.2008.01.088

    authors： Papaleo E,Unfer V,Baillargeon JP,Fusi F,Occhi F,De Santis L

    更新日期：2009-05-01 00:00:00

  • Embryo transfer technique as a cause of ectopic pregnancies in in vitro fertilization.

    abstract：:Against an overall risk of around 2% ectopic pregnancies in in vitro fertilization programs around the world, we report an incidence more than three times greater (5 tubal ectopic pregnancies in 80 clinical in vitro fertilization pregnancies). Of two techniques used for embryo transfers, one produced a significantly h...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)48854-0

    authors： Yovich JL,Turner SR,Murphy AJ

    更新日期：1985-09-01 00:00:00

  • Tubal transport of spermatozoa does not appear to be dependent on normal cilia function.

    abstract：OBJECTIVE:To report the case of a woman with Kartagener's syndrome with complete immotility of ciliae and normal transport of spermatozoa. DESIGN:Case report. PATIENTS:A 31-year-old woman with Kartagener's syndrome. SETTING:Medical university-affiliated teaching hospital. INTERVENTION(S):Ultrasonography, hysterosal...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2006.12.079

    authors： Ott HW,Schmiedehausen K,Kat S,Binder H,Gall C,Kuwert T,Heute D,Virgolini I,Wildt L

    更新日期：2007-11-01 00:00:00

  • The metoclopramid-provocation test for prediction of transient hyperprolactinemia during cycle stimulation.

    abstract：:The predictive value of the metoclopramid-provocation test to detect transient hyperprolactinemia during cycle stimulation was assessed. Patients developing hyperprolactinemia during cycle stimulation showed a significantly higher PRL response to the metoclopramid-provocation test before cycle stimulation. The current...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)53300-7

    authors： Reinthaller A,Neunteufel W,Bieglmayer C,Fischl F

    更新日期：1990-02-01 00:00:00

  • Follicle-stimulating hormone beta gene structure in premature ovarian failure.

    abstract：OBJECTIVE:To determine whether mutations in the gene for FSH beta are present, and possibly etiologic, in some patients with 46,XX premature ovarian failure (POF). DESIGN:DNA samples obtained from 18 study patients with POF and two menopausal fertile controls were studied by Southern blot analysis. DNA sequencing was ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)56286-4

    authors： Layman LC,Shelley ME,Huey LO,Wall SW,Tho SP,McDonough PG

    更新日期：1993-11-01 00:00:00

  • Serum pituitary and steroid hormone levels in the adult male: one value is as good as the mean of three.

    abstract：:The result of the hormone concentration of one blood sample was used to determine the accuracy of predicting not only the hormone concentrations of a second and third sample drawn 15 minutes apart, but also the mean value of the three samples. Three blood specimens from 73 men involved in two previously reported studi...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)59662-9

    authors： Bain J,Langevin R,D'Costa M,Sanders RM,Hucker S

    更新日期：1988-01-01 00:00:00

  • Effects of exposure to high levels of particulate air pollution during the follicular phase of the conception cycle on pregnancy outcome in couples undergoing in vitro fertilization and embryo transfer.

    abstract：:The objective of this retrospective cohort study was to assess the potential effects of preconceptional short-term exposure to particulate air pollution in a real-world situation on pregnancy outcome in infertile women evaluating the possible role of IVF/embryo transfer treatment on this outcome using women who had co...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2009.06.031

    authors： Perin PM,Maluf M,Czeresnia CE,Nicolosi Foltran Januário DA,Nascimento Saldiva PH

    更新日期：2010-01-01 00:00:00

  • Reinsemination by intracytoplasmic sperm injection of 1-day-old oocytes after complete conventional fertilization failure.

    abstract：OBJECTIVE:To analyze the efficacy of intracytoplasmic sperm injection (ICSI) for "rescue" of failed conventional insemination cycles. DESIGN:Retrospective clinical study. SETTING:Private infertility clinic. PATIENT(S):Fifty-four couples with non-male factor infertility undergoing routine IVF within our clinic. INTE...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(97)00223-9

    authors： Morton PC,Yoder CS,Tucker MJ,Wright G,Brockman WD,Kort HI

    更新日期：1997-09-01 00:00:00

  • Ultrasonic evidence for luteinization of unruptured preovulatory follicles.

    abstract：:Luteinization of an unruptured ovarian follicle has been reported as a cause of infertility and has heretofore been diagnosed only by direct visualization of the ovarian surface. Four patients who demonstrated defects in ovulation requiring therapy to induce ovulation and who were not achieving desired conception desp...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)46160-1

    authors： Coulam CB,Hill LM,Breckle R

    更新日期：1982-04-01 00:00:00

  • A call for standardization of fertility clinic websites.

    abstract：:Websites for Society for Assisted Reproductive Technology-affiliated clinics fail to meet most American Medical Association health information guidelines. Professional organizations in reproductive medicine need to standardize the accuracy and appropriateness of online reproductive health information. ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章,评审

    doi：10.1016/j.fertnstert.2004.11.024

    authors： Huang JY,Discepola F,Tulandi T

    更新日期：2005-03-01 00:00:00