Abstract：
:Because the size of leiomyomata uteri often decreases significantly after menopause, the authors elected to employ a long-acting gonadotropin hormone-releasing hormone analog (GnRH-alpha) (imbzl-D-His6-Pro9-Net-GnRH) to create a state of pseudomenopause in six patients with leiomyomata uteri diagnosed on the basis of pelvic examination and confirmed by pelvic ultrasonography. Patients received daily, subcutaneous injections of GnRH-alpha (4 micrograms X kg-1 X 24 hour-1) for 6 months. Uterine size (13.8 +/- 4 weeks [mean +/- standard deviation (SD), n = 6]) was determined by pelvic examination and uterine volume (533.9 +/- 394 ml [mean +/- SD, n = 6]) was determined by pelvic ultrasonography before medical therapy was begun. They observed a decrease in uterine size by pelvic examination within 4 weeks of the initiation of therapy, and all patients experienced a decrease in uterine size (9.5 +/- 4 weeks [mean +/- SD, n = 6]) (P less than 0.05) within 8 weeks of initiation of therapy. After 6 months of therapy, uterine size was 229.5 +/- 145 ml (mean +/- SD, n = 6). During treatment, plasma estrogen concentrations were assessed intermittently (every 1 to 4 weeks) and remained less than 4 pg X ml-1 throughout the period of therapy. All six patients have discontinued therapy. There has been no increase in uterine size in these patients for a period from 3 to 7 months.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Coddington CC,Collins RL,Shawker TH,Anderson R,Loriaux DL,Winkel CAdoi
10.1016/s0015-0282(16)49332-5subject
Has Abstractpub_date
1986-05-01 00:00:00pages
624-9issue
5eissn
0015-0282issn
1556-5653pii
S0015-0282(16)49332-5journal_volume
45pub_type
杂志文章abstract：OBJECTIVE:To evaluate whether the telomere length of white blood cells (WBC) and cumulus cells (CC) in an infertile population is associated with ovarian and embryonic performance. DESIGN:Prospective cohort study. SETTING:Academic-affiliated private practice. PATIENTS:A total of 175 infertile women undergoing in vit...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2020.09.164
更新日期：2020-11-30 00:00:00
abstract：:This prospective study assessed von Willebrand factor (VWF) expression in the endometrium using immunohistochemical staining in women with menorrhagia with or without von Willebrand disease (VWD) compared with a control group of women with normal menstrual loss. Endometrial VWF expression is significantly lower in wom...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2010.02.055
更新日期：2010-11-01 00:00:00
abstract：OBJECTIVE:To develop a consensus regarding the need for luteal phase support during assisted reproductive technology (ART), and to establish the optimal compound and route of administration for this purpose. DESIGN:Review of the published literature on luteal phase support. PATIENT(S):Women undergoing assisted reprod...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/s0015-0282(01)02961-2
更新日期：2002-02-01 00:00:00
abstract：OBJECTIVE:To investigate the effect of curcumin on aflatoxin-induced biochemical changes in testis of mice. DESIGN:Controlled research laboratory study. SETTING:Aflatoxin was obtained by growing Aspergillus parasiticus in SMKY liquid medium. Pure curcumin (97% purity) was purchased from Hi-Media Laboratories Pvt. Ltd...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2007.11.053
更新日期：2009-02-01 00:00:00
abstract：OBJECTIVE:To characterize and to purify the growth substances for mouse embryo fibroblasts (NIH/3T3) and endometrial-like cells of the peritoneal fluid of women with endometriosis. DESIGN:A pool of 102 mL of peritoneal fluid (PF) collected from 24 women with laparoscopic evidence of endometriosis was dialyzed and ther...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:In 115 patients (group I) in which normal liquefaction of semen occurred, the fertilization rate of the yielded oocytes was 71.2% after standard in vitro fertilization procedure, and the viable pregnancy rate per patient per cycle was 13.0%. In a comparable group of 26 patients (group II), in which semen liquefaction ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)60444-2
更新日期：1989-01-01 00:00:00
abstract：:This opinion addresses the ethics of providing fertility treatment to women at elevated risk from fertility treatment or pregnancy. Providers ethically may treat women at elevated risk provided that they are carefully assessed; that specialists in their medical condition are consulted as appropriate; and that patients...
journal_title：Fertility and sterility
pub_type： 杂志文章,实务指引
doi：10.1016/j.fertnstert.2016.08.015
更新日期：2016-11-01 00:00:00
abstract：:Selective uterine devascularization before myomectomy at the time of cesarean section is a novel technique that facilitates myomectomy and is a safe procedure avoiding the need for subsequent surgery. ...
journal_title：Fertility and sterility
pub_type： 信件
doi：10.1016/j.fertnstert.2009.09.027
更新日期：2010-06-01 00:00:00
abstract：:The effects of estradiol (E2) administered by a transdermal system on the induction of hypothalamic opioid activity was examined in 18 postmenopausal women. Women were given 25, 50, 100, or 200 micrograms/d dosages of E2 for 28 days each. Naloxone at a dosage of 2 mg/h was infused intravenously for 4 hours, and serum ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1991-04-01 00:00:00
abstract：OBJECTIVE:To evaluate whether microfluidic sperm sorters (MFSSs) allow effective recovery of sorted motile sperm without DNA damage compared with the centrifugation and swim-up procedure. DESIGN:Experimental laboratory study. All participants completed questionnaires regarding previous and/or current diseases, surgery...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2015.10.023
更新日期：2016-02-01 00:00:00
abstract：OBJECTIVE:To report the transcervical and transisthmic evacuation of a dichorionic interstitial twin pregnancy guided by ultrasound. DESIGN:Case study. SETTING:Fetal medicine unit of university hospital. PATIENT(S):Dichorionic twin fetuses. INTERVENTION(S):Three-dimensional/four-dimensional (3D/4D) ultrasound-guide...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2011.07.1145
更新日期：2011-10-01 00:00:00
abstract：OBJECTIVE:To determine the effect of hormone replacement therapy (HRT) on cardiac structure and function and whether these changes are related to changes in blood volume. DESIGN:Open-label pilot study. SETTING:Academic medical center. PATIENT(S):Eighteen healthy postmenopausal women. INTERVENTION(S):We administered...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/s0015-0282(98)00398-7
更新日期：1999-01-01 00:00:00
abstract：:To evaluate the effectiveness of intravenous metoclopramide, alone or in combination with luteinizing hormone-releasing hormone (LH-RH), in distinguishing between constitutional delay of puberty and hypogonadotropic hypogonadism, 12 patients with constitutional delay of puberty and 10 patients with hypogonadotropic hy...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)60788-4
更新日期：1989-07-01 00:00:00
abstract：OBJECTIVE:To emphasize the importance of complete ultrasonographic evaluation during the first trimester of pregnancy. DESIGN:Case report. SETTING:Obstetric unit in a training and research hospital. PATIENT(S):A 27-year-old primigravida woman who reached 37 weeks' gestation with a noncommunicating rudimentary horn p...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2009.08.027
更新日期：2009-12-01 00:00:00
abstract：:Semen specimens were obtained for analysis from nine men immediately before vasectomy and 3 days following the vasectomy procedure. After vasectomy there was a significant decrease in seminal sperm concentration, percentage of sperm motility, and mean swimming speed. In seven of nine cases the spermatozoa did not surv...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)48262-2
更新日期：1984-12-01 00:00:00
abstract：OBJECTIVE:To conduct a pilot study to investigate the possible presence of bacteria throughout the female reproductive tract and to make a preliminary assessment of whether there are differences in the composition of the microbial communities between these body sites and/or between patients. DESIGN:Prospective pilot s...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2016.11.028
更新日期：2017-03-01 00:00:00
abstract：OBJECTIVE:To assess the correlation between in vitro fertilization (IVF) and complications of the third stage of labor. DESIGN:Retrospective cohort of vaginal deliveries from November 2008 to January 2020. Maternal and obstetric outcomes of singleton deliveries were compared between IVF and non-IVF pregnancies. SETTI...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2020.10.004
更新日期：2020-11-30 00:00:00
abstract：OBJECTIVE:To determine whether the G1733A polymorphism of the androgen receptor gene is associated with an increased risk for recurrent spontaneous abortion (RSA). DESIGN:Case-control study. SETTING:Division of Genetics and Biotechnology, Department of Biology, University of Athens. PATIENT(S):A total of 131 women w...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.04.071
更新日期：2008-11-01 00:00:00
abstract：OBJECTIVE:To investigate whether the antiprogestin RU486 acts primarily on the hypothalamus to delay the midcycle gonadotropin surge and thus gain insight into the site(s) of action of P in the control of ovulation. DESIGN:Prospective, crossover, single-blinded clinical study. SETTING:Outpatient clinic in an academic...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/s0015-0282(16)56811-3
更新日期：1994-07-01 00:00:00
abstract：:The assessment of anti-phospholipid antibodies (APA) is not indicated among couples undergoing IVF, and therapy is not justified on the basis of existing data. ...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2008.08.100
更新日期：2008-11-01 00:00:00
abstract：OBJECTIVE:To study the link between fatness and gonadotropin secretion. Overweight status is linked to polycystic ovary syndrome (PCOS) in adolescents. We postulated that heavier adolescents without symptoms would secrete LH with: [1] increased pulse frequency (LHPF) and [2] exaggerated integrated concentrations (LHAUC...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2009.02.072
更新日期：2010-06-01 00:00:00
abstract：OBJECTIVE:To describe different approaches for diagnosis and management of proximal ectopic pregnancies (PP) in general population. DESIGN:Observational population based-study. SETTING:Regional ectopic pregnancy registry. PATIENT(S):Eighty-six PP registered from 1992 to 2008. INTERVENTION(S):Surgical (radical or co...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2010.10.025
更新日期：2011-03-01 00:00:00
abstract：OBJECTIVE:To evaluate by serial ultrasound scans how long a Ringer's lactate instillation remains in the peritoneal cavity after laparoscopy. DESIGN:Prospective, randomized, double blind, clinical trial. SETTING:Tertiary care, university hospital. PATIENT(S):Thirty-six patients undergoing diagnostic or minor operati...
journal_title：Fertility and sterility
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.fertnstert.2005.01.111
更新日期：2005-07-01 00:00:00
abstract：:In 6-day pregnant New Zealand White rabbits dosed intravenously with 3H-nicotine, the 3H-activity in the uterine fluid was approximately 5 to 11 times greater than that in the plasma at the corresponding times; 3H-nicotine itself accounted for most of this radioactivity. Dichlorodiphenyltrichloroethane (DDT) also accu...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1976-10-01 00:00:00
abstract：OBJECTIVE:To compare clinical outcomes of frozen embryo transfers using cryopreserved pronuclear stage oocytes that had undergone either intracytoplasmic sperm injection (ICSI) or conventional IVF. DESIGN:Observational. SETTING:A tertiary referral reproductive medicine unit. PATIENT(S):Couples undergoing either ICSI...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/s0015-0282(99)00444-6
更新日期：1999-12-01 00:00:00
abstract：:Where histology used the presence of glands and/or stroma in the myometrium as pathognomonic for adenomyosis, imaging uses the appearance of the myometrium, the presence of striations, related to the presence of endometrial tissue within the myometrium, the presence of intramyometrial cystic structures and the size an...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2018.01.006
更新日期：2018-03-01 00:00:00
abstract：OBJECTIVE:To identify the most important factor in predicting ovarian reserve after laparoscopic ovarian cystectomy and to evaluate whether there is any difference in the postoperative decline of ovarian reserve between women with endometrioma and those with other benign ovarian cysts. DESIGN:Prospective cohort study....
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2013.10.043
更新日期：2014-02-01 00:00:00
abstract：OBJECTIVE:To determine whether there is a difference in fibrinolytic compounds in endometriotic tissue, endometrium, peritoneal fluid (PF), and plasma from women with endometriosis and in endometrium and PF from healthy women. DESIGN:Prospective study. SETTING:Two university clinics. PATIENT(S):Regularly menstruatin...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(98)00285-4
更新日期：1998-11-01 00:00:00
abstract：:It is clear that women with primary ovarian insufficiency are asking the health care community to alter the current standard, which requires the patient to seek a different specialist for each of her health care needs, and instead work as a team of caregivers that embraces each patient as a woman with complex and indi...
journal_title：Fertility and sterility
pub_type： 评论,杂志文章
doi：10.1016/j.fertnstert.2011.03.006
更新日期：2011-05-01 00:00:00
abstract：:Follow-up of 54 patients undergoing modified single-layer bilateral vasovasostomies are presented with attention to semen quality, pregnancy rates, and postoperative findings potentially inhibiting fertility. The technical success rate was 98%, but 3-month semen analyses varied from "poor" (less than 20(6)/ml; greater...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)47789-7
更新日期：1984-04-01 00:00:00
