Triple ultrasound markers including fetal cardiac activity are related to miscarriage risk.

Abstract:

OBJECTIVE:To identify early ultrasound markers in pregnant patients that predict a favorable pregnancy outcome. DESIGN:Retrospective case-control study. SETTING:Infertility patients in fertility clinic. PATIENT(S):1051 women with early pregnancies conceived after fertility treatment. INTERVENTION(S):None. MAIN OUTCOME MEASURE(S):Ongoing pregnancy >20 weeks' gestation. RESULT(S):Ongoing pregnancy rate was 90.5% for those pregnancies having early fetal cardiac activity (odds ratio [OR] = 66.5). Gestational sac diameter ≥12 mm was associated with ongoing pregnancy rate of 91.9%. Small gestational sac diameter, <8 mm, was associated with high miscarriage rate, 85.3%. Ongoing pregnancy rates for yolk sac diameter <2 mm, 2-6 mm, and >6 mm were 20%, 89.2%, and 20%, respectively (OR = 33.1, 2-6 vs <2 mm; OR = 33.1, 2-6 vs >6 mm). Ongoing pregnancy rate was 94% when all three markers were present. CONCLUSION(S):On postconception days 33-36, gestational sac diameter ≥12 mm, yolk sac diameter 2-6 mm, and the presence of fetal cardiac activity were favorable markers.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Bae S,Karnitis J

doi

10.1016/j.fertnstert.2011.08.009

subject

Has Abstract

pub_date

2011-11-01 00:00:00

pages

1145-8

issue

5

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(11)02428-9

journal_volume

96

pub_type

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