Abstract:
:The interaction between human uterine secretions and human spermatozoa was studied. Secretions were obtained by washing the endometrial surfaces of normal uteri removed at surgery and collecting uterine fluid by incubating Millipore chambers in the uteri of volunteers. A microtechnique was devised for conducting metabolic studies with the small volumes (50 microliters) of fluid obtained in the chamber. The uterine secretions obtained by these two methods reduced the formation of CO2 by sperm from labeled glucose without affecting the accumulation of lactic acid. Sperm motility was not affected during a 3-hour incubation period. Uterine washings also reduced the rate of oxygen uptake of treated sperm. The metabolic alteration may have the effect of prolonging the life-span of spermatozoa within the female tract.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Trifunac NP,Bernstein GSdoi
10.1016/s0015-0282(16)45259-3subject
Has Abstractpub_date
1981-01-01 00:00:00pages
58-63issue
1eissn
0015-0282issn
1556-5653pii
S0015-0282(16)45259-3journal_volume
35pub_type
杂志文章abstract::The role of insulin sensitizing agents is discussed at length in this Committee Opinion. ...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/j.fertnstert.2008.08.004
更新日期:2008-11-01 00:00:00
abstract::Anatomic distances along retroperitoneal, inguinal, and infrainguinal segments of the vas deferens were measured in 14 formalin fixed cadavers and in 15 recently postmortem males. There were no significant differences in segment lengths between the two groups nor between the right and left vasa. Data from the recent p...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)53959-4
更新日期:1990-11-01 00:00:00
abstract:OBJECTIVE:To assess the clinical value of bisulfite polymerase chain reaction Luminex (BPL), an automated, high-throughput procedure for the detection of alterations in DNA methylation. DESIGN:Experimental prospective study. SETTING:University research laboratory and private in vitro fertilization (IVF) clinic. PATI...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章
doi:10.1016/j.fertnstert.2010.06.076
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVE:To determine the impact of a cryopreservation program on pregnancy rates and multiple-pregnancy rates in ART cycles. DESIGN:Retrospective study. SETTING:University teaching hospital. PATIENT(S):Women who underwent stimulation for in vitro fertilization at the Jones Institute for Reproductive Medicine betwe...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(00)01661-7
更新日期:2001-01-01 00:00:00
abstract::This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2013.08.053
更新日期:2013-10-07 00:00:00
abstract::Many women now choose to develop their careers before having children. Thus, it is becoming increasingly important to assess a woman's potential for extended fertility and to understand the health consequences of having children at a late age. In particular, there is a striking positive correlation between extended fe...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/j.fertnstert.2015.02.008
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVE:To ascertain whether obstetric, gynecologic, or congenital variables affect implantation efficiency or eventual delivery in donor oocyte recipients. DESIGN:Clinical study. SETTING:Academic tertiary care infertility clinic. PATIENT(S):A total of 370 recipients. INTERVENTION(S):Fresh ET following oocyte don...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章
doi:10.1016/s0015-0282(98)00420-8
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the expression, regulation, and role of interleukin (IL)-8 in human ovary. DESIGN:Prospective study. SETTING:University hospital. PATIENT(S):Sixteen premenopausal women. INTERVENTION:Follicular fluid and granulosa lutein cells (GLCs) were collected during IVF cycles. Ovarian stromal and theca ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(02)04408-4
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:To investigate chorionic villous vasculogenesis (maturation) and development of the vasculosyncytial membrane (margination) using CD34 immunohistochemistry. DESIGN:Case-control study. SETTING:Microscopic analysis of first trimester chorionic villi. PATIENT(S):Twelve patients with anembryonic pregnancies, 1...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2004.02.119
更新日期:2004-09-01 00:00:00
abstract:OBJECTIVE:To study concordance rates of cryptorchidism (undescended testis) in pairs of boys with varying family structure, to evaluate the risk contribution from the intrauterine environment and genetic factors. DESIGN:Population based study of 1,024,500 Danish boys born from January 1, 1973 to December 31, 2004. Cla...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.09.041
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:To evaluate serum inhibin B as a predictor of poor ovarian response in patients undergoing in vitro fertilization/intracytoplasmic sperm injection (IVF-ICSI) and to compare it with the performance of antimüllerian hormone (AMH). DESIGN:Meta-analysis. SETTING:University hospital. PATIENT(S):Patients undergo...
journal_title:Fertility and sterility
pub_type: 杂志文章,meta分析
doi:10.1016/j.fertnstert.2011.07.1102
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVE:To study the messenger ribonucleic acid (mRNA) expression of receptors for insulin, insulin-like growth factor I (IGF-I), and insulin-like growth factor II (IGF-II) in human fetal ovaries and uteri at 10, 15, 19, and 22 weeks' gestation. Insulin, IGF-I, and IGF-II are postulated to have paracrine and autocrin...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)55924-x
更新日期:1993-05-01 00:00:00
abstract:OBJECTIVE:To investigate the potential effects of TAT-PRDX2 protein supplementation to the cryopreservation medium on post-thaw sperm quality and function. DESIGN:In vitro prospective study. SETTING:Medical university hospital. PATIENT(S):Fifty normozoospermic, 50 asthenozoospermic, and 50 oligoasthenozoospermic men...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2018.07.008
更新日期:2018-11-01 00:00:00
abstract::We found the prevalence of ovarian cancer in infertile women less than 40 years at the time of planned microsurgery for infertility to be 1 in 95. This may represent a greater prevalence of ovarian cancer than that of all women less than 40 years. Importantly, laparoscopy did not find the ovarian cancer in these women...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1988-03-01 00:00:00
abstract:OBJECTIVE:To compare the effects of intrauterine and subdermal administration of levonorgestrel on control of bleeding and on the endometrium in postmenopausal hormone replacement therapy. INTERVENTIONS:Nineteen women started continuous oral E2 valerate therapy (2 mg daily) together with continuous parenteral progesti...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0015-0282(16)57365-8
更新日期:1995-02-01 00:00:00
abstract:OBJECTIVE:To present the first clinical pregnancy after uterus transplantation. DESIGN:Case study. SETTING:Tertiary center. PATIENT(S):A 23-year-old Mayer-Rokitansky-Kuster-Hauser syndrome patient with previous vaginal reconstruction and uterus transplantation. INTERVENTION(S):Eighteen months after the transplant, ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2013.06.027
更新日期:2013-11-01 00:00:00
abstract::The histologic appearance of the testes of men exposed to chronic gonadotropin-releasing hormone agonist (GnRH-A) therapy has not been previously documented. Herein, we report on the histologic features of the testes of four patients with disseminated prostatic carcinoma who received at least 1 year of daily treatment...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)48205-1
更新日期:1984-11-01 00:00:00
abstract:OBJECTIVE:To examine the spatiotemporal expression of CD9 protein in the peri-implantation mouse uterus as well as the effects of ovarian steroid hormones on CD9. DESIGN:Experimental animal study. SETTING:Reproductive biological center of Chinese Academy of Sciences. ANIMAL(S):Female Kunming white strain mice (6-8 w...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2006.07.1525
更新日期:2007-03-01 00:00:00
abstract:OBJECTIVE:To examine the relationship of ovulation-inducing drugs and ovarian cancer. DESIGN:Retrospective cohort study, with additional follow-up since initial report. SETTING:Five large reproductive endocrinology practices. PATIENT(S):In a retrospective cohort of 9,825 women evaluated for infertility at five clini...
journal_title:Fertility and sterility
pub_type: 杂志文章,多中心研究
doi:10.1016/j.fertnstert.2013.08.008
更新日期:2013-12-01 00:00:00
abstract::The concentrations of pregnanediol-3-glucuronide (PGD) and pregnanolone (PN) were measured in daily morning urine specimens from 66 infertile women (40 with varying degrees of endometriosis and 26 control subjects) and correlated with daily changes in basal body temperature (BBT) and with midluteal levels of serum pro...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1983-11-01 00:00:00
abstract::A cryopreserved sperm sample with a low level of DNA fragmentation was used for intracytoplasmic sperm injection and resulted in a twin birth from a couple with a 10-year history of idiopathic infertility. ...
journal_title:Fertility and sterility
pub_type: 信件
doi:10.1016/j.fertnstert.2003.11.010
更新日期:2004-03-01 00:00:00
abstract:OBJECTIVE:To identify the value that women with pelvic inflammatory disease (PID) assign to the health impact of future infertility. DESIGN:Cross-sectional observations on patient preferences. SETTING:Participants in an existing multicenter clinical trial of PID treatment options. PATIENT(S):Five hundred thirty-two ...
journal_title:Fertility and sterility
pub_type: 杂志文章,多中心研究
doi:10.1016/j.fertnstert.2003.09.064
更新日期:2004-05-01 00:00:00
abstract:OBJECTIVE:To analyze the results of ongoing pregnancies and deliveries after assisted reproductive technology (ART) in women aged >/=41 years, stratified by year of age. DESIGN:Retrospective study. SETTING:University hospital, IVF unit. PATIENT(S):A total of 431 IVF and intracytoplasmic sperm injection (ICSI) cycles...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(00)00697-x
更新日期:2000-09-01 00:00:00
abstract::Three groups of dogs underwent testicular ischemia for a 3-hour period. Group I (10 animals) was not subsequently perfused. Group II (10 animals) underwent subsequent perfusion by a new in vivo reversible method via the internal spermatic artery with heparinized saline. Group III (5 animals) underwent perfusion with S...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)42924-9
更新日期:1977-11-01 00:00:00
abstract:OBJECTIVE:To evaluate the safety of a new ultravitrification closed device. DESIGN:Ultravitrification research. SETTING:Private assisted reproduction center. ANIMAL(S):Microorganisms (bacteria). INTERVENTION(S):A styrofoam container holding 1,000 mL of liquid nitrogen (LN2) was contaminated with Pseudomonas aerugin...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2010.12.044
更新日期:2011-04-01 00:00:00
abstract::The present study was undertaken to investigate not only the effectiveness of bromoergocryptine therapy in 13 women with amenorrhea-galactorrhea and hyperprolactinemia without evidence of organic pathology, but also to assess the value of pretreatment evaluation in predicting the response to therapy. Sella turcica tom...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)42490-8
更新日期:1977-04-01 00:00:00
abstract::Embryo transfer is arguably the most critical process in the sequential events that encompass an IVF cycle. Several variables play a role in the success of a transfer, including catheter type, atraumatic technique, and the use of ultrasound guidance. The inclusion of hyaluronan in the ET media also has a benefit for i...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/j.fertnstert.2016.02.022
更新日期:2016-04-01 00:00:00
abstract::Incubation of cervical mucus with the proteolytic enzyme bromelin is known to result in complete liquefaction of the gel. This effect has been used in the detection spermagglutinating antibodies in cervical mucus. However, the well-known papain-like effect of bromelin on human immunoglobulin G (IgG) might be expected ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)44480-8
更新日期:1980-01-01 00:00:00
abstract::In this observational, case-control study in infertile women, we observed elevated serum oxidative stress that was significantly correlated with an increase in serum paraoxonase-1 activity and without any evidence of a proinflammatory reaction. These results suggest a protective role of paraoxonase-1 against inflammat...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2009.11.043
更新日期:2010-08-01 00:00:00
abstract:OBJECTIVE:To determine whether a history of prior cesarean delivery (CD) makes ET more difficult and impacts pregnancy outcomes. DESIGN:Prospective cohort study. SETTING:Tertiary care military facility. PATIENT(S):One hundred ninety-four patients with previous delivery undergoing IVF/intracytoplasmic sperm injection...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2016.03.045
更新日期:2016-08-01 00:00:00