Effect of human endometrial secretions on the metabolism of human spermatozoa.

Abstract:

:The interaction between human uterine secretions and human spermatozoa was studied. Secretions were obtained by washing the endometrial surfaces of normal uteri removed at surgery and collecting uterine fluid by incubating Millipore chambers in the uteri of volunteers. A microtechnique was devised for conducting metabolic studies with the small volumes (50 microliters) of fluid obtained in the chamber. The uterine secretions obtained by these two methods reduced the formation of CO2 by sperm from labeled glucose without affecting the accumulation of lactic acid. Sperm motility was not affected during a 3-hour incubation period. Uterine washings also reduced the rate of oxygen uptake of treated sperm. The metabolic alteration may have the effect of prolonging the life-span of spermatozoa within the female tract.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Trifunac NP,Bernstein GS

doi

10.1016/s0015-0282(16)45259-3

subject

Has Abstract

pub_date

1981-01-01 00:00:00

pages

58-63

issue

1

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(16)45259-3

journal_volume

35

pub_type

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