Abstract：
OBJECTIVE:To report the inheritance of a pericentric inversion in chromosome 7 through the three progenies, congenital hydronephrosis, and recurrent miscarriages in an extended family. DESIGN:Case report. SETTING:Medical Faculty of Cukurova University in Turkey. PATIENT(S):Referred by obstetrics and gynecology clinic. INTERVENTION(S):Fetal urine and lymphocytic karyotype. MAIN OUTCOME MEASURE(S):Chromosomal analysis from fetal urine and peripheral blood lymphocytes were performed according to standard cytogenetic methods. RESULT(S):We assessed an extended family in which a large pericentric inversion in chromosome 7 is segregating; one of the three progenies with the karyotype 46,XY,inv(7)(p22;q22) was heterozygote for the inversion and presented with congenital hydronephrosis. His mother, mother's brother, grandfather, grandfather's brother, and his daughter were similar for the inversion. CONCLUSION(S):This case describes the further molecular characterization of these breakpoints on the short or long arm of chromosome 7(p22-q22). The inv(7) is also associated with fetal wastage and may be playing a role in the etiology of the family's miscarriages. These findings can be used in clinical genetics and may be an effective tool for reproductive guidance and genetic counseling.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Demirhan O,Ozcan K,Taştemir D,Demir C,Tunç E,Solğun HA,Güzel AIdoi
10.1016/j.fertnstert.2007.02.030subject
Has Abstractpub_date
2008-01-01 00:00:00pages
228.e1-6issue
1eissn
0015-0282issn
1556-5653pii
S0015-0282(07)00410-4journal_volume
89pub_type
杂志文章abstract：:Polycystic ovary syndrome presents with many different symptoms and signs, for which different therapies are indicated. However, for the majority of women, the metabolic disorder requires diligence in management, regardless of the presenting complaint. ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2006.03.011
更新日期：2006-07-01 00:00:00
abstract：OBJECTIVE:A practical attempt to simplify and improve the technique of artificial uterine cavity distension by instilling gel instead of flushing saline. DESIGN:Prospective observational study. SETTING:Teaching hospital. PATIENT(S):One hundred twenty patients with an indication for sonohysterography (abnormal uterin...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2006.05.075
更新日期：2007-01-01 00:00:00
abstract：OBJECTIVE:To describe patients who at least once did not reply to correspondence of the center about embryo disposition. DESIGN:Anonymous questionnaire. SETTING:Department of Reproductive Medicine, Ghent University Hospital (Belgium). PATIENT(S):Patients whose embryos were stored for at least 2 years. INTERVENTION(...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2011.02.033
更新日期：2011-05-01 00:00:00
abstract：OBJECTIVE:To analyze prognostic factors that are associated with a discordant outcome in egg recipients sharing oocytes from the same donor. DESIGN:Matched case-control single-center study. SETTING:Private infertility clinic. PATIENT(S):Four hundred forty-four recipients (222 pairs) sharing oocytes from the same don...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2007.01.054
更新日期：2007-12-01 00:00:00
abstract：OBJECTIVE:To examine sperm motility, total antioxidant level (TAC), DNA fragmentation, and medical history in infertile men with high seminal high reactive oxygen species (ROS). DESIGN:Prospective study. SETTING(S):Tertiary care hospital. PATIENT(S):Infertile men (n=101). INTERVENTION(S):Group I (n=57) included men...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2009.12.030
更新日期：2010-11-01 00:00:00
abstract：OBJECTIVE:To evaluate the safety profile of endometrial ablation performed with a thermal balloon as defined by serosal temperature elevation and depth of injury. DESIGN:Observational study with histopathologic correlation conducted in ex vivo and in vivo phases. SETTING:Academic medical center. PATIENT(S):Twenty pa...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(98)00245-3
更新日期：1998-10-01 00:00:00
abstract：:A laparotomy was performed in 40 rats and the cecum was subjected to a standardized trauma. Half the rats were treated with oxyphenbutazone in a dose of 40 mg/kg body weight daily for 14 days. The remaining 20 rats served as controls. All of the rats were killed 2 weeks after the laparotomy, and the number of intraper...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)42731-7
更新日期：1977-08-01 00:00:00
abstract：OBJECTIVE:To evaluate the effectiveness of progestogen supplementation in improving clinical pregnancy rates in women undergoing fresh IVF cycles and to compare different routes, start times, durations, and estrogen coadministration regimen. DESIGN:Comprehensive systematic review and meta-analysis. SETTING:University...
journal_title：Fertility and sterility
pub_type： 杂志文章,meta分析
doi：10.1016/j.fertnstert.2019.04.021
更新日期：2019-09-01 00:00:00
abstract：OBJECTIVE:To investigate the ability of N-formyl-methionyl-leucyl-phenylalanine (f-MLP), complement 5a (C5a), and nerve growth factor (NGF) to stimulate human spermatozoal reactive oxygen species generation in fertile and infertile patients. DESIGN:Prospective, controlled study measuring human spermatozoal reactive ox...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)55874-9
更新日期：1993-04-01 00:00:00
abstract：:The biochemical and histological features of two related patients with the complete form of the androgen insensitivity syndrome (AIS) coexisting with incomplete regression of the Müllerian ducts are described. Both patients presented unilateral Müllerian derivatives (fallopian tube) identified by microscopic examinati...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1990-06-01 00:00:00
abstract：:The transcervical division of uterine septa is usually described as a simple procedure associated with minimal morbidity. Two cases are presented describing late hemorrhage after this procedure. Approaches to avoiding this complication as well as management principles are described. ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)54984-x
更新日期：1992-04-01 00:00:00
abstract：OBJECTIVE:To investigate the relationship between endogenous serum levels of human growth hormone (hGH) and ovarian response to human menopausal gonadotropins (hMG). DESIGN:Retrospective analysis of patient response to hMG. SETTING:Center for assisted reproductive technology. PATIENTS:Eighty women who had undergone ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)55133-4
更新日期：1992-07-01 00:00:00
abstract：OBJECTIVE:To investigate whether polymorphisms at the promoter or 5'-untranslated region of annexin A5 gene (ANXA5) influence miscarriage. DESIGN:Case-control study and nested case-control study. SETTING:Hospitals. PATIENT(S):A total of 264 patients with two to nine recurrent pregnancy losses (RPLs) and 195 fertile ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2013.06.020
更新日期：2013-10-01 00:00:00
abstract：:The histologic appearance of the testes of men exposed to chronic gonadotropin-releasing hormone agonist (GnRH-A) therapy has not been previously documented. Herein, we report on the histologic features of the testes of four patients with disseminated prostatic carcinoma who received at least 1 year of daily treatment...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)48205-1
更新日期：1984-11-01 00:00:00
abstract：OBJECTIVE:To study attitudes about posthumous assisted reproduction (PAR) in individuals presenting for assisted reproduction, to examine the degree of concordance of attitudes within couples, and to determine whether individuals can accurately predict the attitudes of their intimate partners. DESIGN:Cross sectional s...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2011.09.018
更新日期：2011-12-01 00:00:00
abstract：OBJECTIVE:To investigate whether abnormalities in serum concentrations of 1,25-dihydroxyvitamin D [1,25(OH)(2)D], 25-hydroxyvitamin D [25(OH)D], parathyroid hormone (PTH), calcium, and phosphorus were associated with risk of polycystic ovary syndrome (PCOS) and obesity. The possible correlations of the calciotropic hor...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.11.031
更新日期：2010-03-01 00:00:00
abstract：OBJECTIVE:To determine the fertility potential of women with congenital ampullary atresia of the fallopian tube. DESIGN:Case report and review of literature. SETTING:University-affiliated tertiary care infertility clinic. PATIENT(S):Six infertile women with congenital ampullary atresia of the oviduct. INTERVENTION(...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(02)04691-5
更新日期：2003-02-01 00:00:00
abstract：OBJECTIVE:To investigate c-fos and matrix metalloproteinase-9 (MMP-9) expression in the endometrium from women with or without endometriosis throughout the menstrual cycle, and to explore the correlation of c-fos expression with MMP-9 expression and 17beta-E(2) levels in serum. DESIGN:Molecular studies in human tissue...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2007.07.1386
更新日期：2008-10-01 00:00:00
abstract：:In a study of 29 cycles of IVF, ET was performed on day 5 after oocyte recovery when embryos had developed to the morula/blastocyst stage. Three preclinical pregnancies and three live births resulted (2 singleton and 1 twin), giving a viable PR per ET of 10%. It is concluded that while day 5 ET may well be important i...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)54257-5
更新日期：1991-04-01 00:00:00
abstract：OBJECTIVE:To investigate whether immunological mechanisms may be involved in human luteal function. DESIGN:The effects of the cytokines, interferon-alpha (IFN-alpha), interferon-gamma (IFN-gamma) and tumor necrosis factor alpha (TNF-alpha) on steroidogenesis by human luteal cells were examined in vitro. The dispersed ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1992-11-01 00:00:00
abstract：OBJECTIVE:To develop a technique with the potential of isolating genetically fit sperm for assisted reproductive technology (ART) treatment without compromising its structural or functional competence. DESIGN:Observational study. SETTING:University hospital. PATIENT(S):Fifty patients undergoing infertility diagnosis...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2014.10.047
更新日期：2015-02-01 00:00:00
abstract：:A patient with Nelson's syndrome whose pregnancy was complicated by symptomatic enlargement of an ACTH-producing pituitary tumor was described. Emergency ablative surgery was performed with successful outcomes for both mother and infant. ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)48932-6
更新日期：1985-10-01 00:00:00
abstract：OBJECTIVE:To evaluate the effect of adding follicular-fluid meiosis-activating sterol (FF-MAS) in a novel 0.2% recombinant human albumin-based formulation to cumulus-enclosed oocytes on chromosomal status and development of pre-embryos. DESIGN:Multicenter, prospective, randomized, open (double-blind for vehicle and FF...
journal_title：Fertility and sterility
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.fertnstert.2005.05.017
更新日期：2005-10-01 00:00:00
abstract：OBJECTIVE:To assess in utero exposures and the odds of an endometriosis diagnosis. DESIGN:Matched cohort design. SETTING:Fourteen participating clinical centers in geographically defined areas in Utah and California. PATIENT(S):Operative cohort comprised 473 women undergoing laparoscopy/laparotomy, and an age- and r...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2012.11.013
更新日期：2013-03-01 00:00:00
abstract：OBJECTIVE:To determine if the addition of fibrin sealant to incision closure in a rabbit uterine horn myomectomy model affects adhesion formation or strength of incision closure. DESIGN:Prospective randomized controlled trial. SETTING:Academic research center. ANIMAL(S):New Zealand white female rabbits. INTERVENTIO...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2005.07.1337
更新日期：2006-04-01 00:00:00
abstract：OBJECTIVE:To improve the sperm chromatin dispersion (SCD) test and develop it as a simple kit (Halosperm kit) for the accurate determination of sperm DNA fragmentation using conventional bright-field microscopy. DESIGN:Method development, comparison, and validation. SETTING:Medical genetics laboratory, academic biolo...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2004.11.089
更新日期：2005-10-01 00:00:00
abstract：OBJECTIVE:To evaluate whether circulating levels of antimüllerian hormone (AMH) predict fecundability in young healthy women. DESIGN:Prospective cohort study. SETTING:General community. PATIENT(S):A total of 186 couples who intended to discontinue contraception to become pregnant were followed until pregnancy or for...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2012.08.008
更新日期：2012-12-01 00:00:00
abstract：OBJECTIVE:To determine whether magnetic resonance imaging (MRI) and serum levels of CA-125 can be used to evaluate patients with endometriomas before initiating medical treatment. DESIGN:Comparative study before and after medical treatment. SETTING:Shimane Medical University Hospital, Izumo, Japan. PATIENTS:Eleven c...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/s0015-0282(16)58087-x
更新日期：1996-02-01 00:00:00
abstract：OBJECTIVE:To investigate endometrial dating during the conception cycle. DESIGN:Endometrial biopsies of the last half of the luteal phase of conception cycles were dated based on urinary luteinizing hormone (LH) surges. SETTING:Endometrial samples were obtained from women attending the fertility clinic of the Departm...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1992-12-01 00:00:00
abstract：OBJECTIVE:To determine the cumulative incidence of live delivery in women who underwent reversal of tubal sterilization. DESIGN:Population-based retrospective cohort study. SETTING:Hospitals in Western Australia. PATIENT(S):All women aged 20-44 years, with a history of hospital admission for tubal sterilization, who...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2015.06.042
更新日期：2015-10-01 00:00:00
