Male fertility in factor XIII deficiency.

Abstract:

:Seven homozygotes for F-XIII deficiency were found in a large inbred Israeli-Arab kindred. One affected woman had early abortions. Two affected men and one probably affected man had children, two of whom also were affected. Paternity was confirmed by segregation of HLAs and erythrocyte antigens and enzymes. This is the first documentation of normal male fertility in unequivocally affected patients. Clinical variability or genetic heterogeneity may account for previously reported male infertility.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Frydman M,Bonne-Tamir B,Braude E,Zamir R,Creter D

doi

10.1016/s0015-0282(16)49351-9

subject

Has Abstract

pub_date

1986-05-01 00:00:00

pages

729-31

issue

5

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(16)49351-9

journal_volume

45

pub_type

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