Abstract：
OBJECTIVE:To evaluate the interactive effects of dietary soy and menstrual cycle phase on breast proliferation, apoptosis, and sex steroid receptor expression in premenopausal female cynomolgus monkeys. DESIGN:Animals were randomized to receive diets with either casein lactalbumin or soy as the protein source for 12 months. Paired follicular and luteal mammary gland biopsies were taken before and after treatment and evaluated for epithelial proliferation and area, apoptosis, and sex steroid receptor expression. SETTING:Academic research environment. ANIMAL(S):Fifty-two adult female cynomolgus monkeys (Macaca fascicularis). INTERVENTION(S):Soy protein with the human equivalent of 129 mg/d of isoflavones. MAIN OUTCOME MEASURE(S):Breast proliferation and epithelial area. RESULT(S):Follicular and luteal assessments were taken on cycle day (+/- SE) 5.3 +/- 0.1 and 22.0 +/- 0.1, respectively. Serum E2, serum P, breast proliferation, and vaginal maturation were significantly higher in the luteal vs. follicular phase. Soy treatment resulted in significantly higher serum isoflavone concentrations compared with the casein lactalbumin group but did not significantly affect breast proliferation, epithelial area, apoptosis, or progesterone receptor expression; uterine size; or vaginal maturation in either the follicular or luteal phase. CONCLUSION(S):Results indicate that dietary levels of soy intake have no detectable hormonal effects on the premenopausal breast.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Wood CE,Kaplan JR,Stute P,Cline JMdoi
10.1016/j.fertnstert.2005.08.059subject
Has Abstractpub_date
2006-04-01 00:00:00pages
1179-86eissn
0015-0282issn
1556-5653pii
S0015-0282(05)04191-9journal_volume
85 Suppl 1pub_type
杂志文章abstract：:Comparative studies have been carried out on the behavior of human and bovine spermatozoa toward homologous cervical mucus in vitro. In both cases the degree of sperm penetration and the pattern of sperm motility were influenced in a characteristic fashion by prior manipulation of the mucus: the most rapid and extensi...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1980-06-01 00:00:00
abstract：OBJECTIVE:To evaluate the potential clinical application of Raman spectroscopy (RS) as a tool that may identify spermatogenesis within human seminiferous tubules. DESIGN:RS scanning of human testicular tissue at different maturational stages; immunohistochemistry study and metabolomic analysis of nonobstructive azoosp...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2014.03.035
更新日期：2014-07-01 00:00:00
abstract：OBJECTIVE:To analyze relationship and parenthood in IVF twin couples, IVF singleton couples, and spontaneously pregnant primiparous couples. SETTING:Southeast region of Sweden. DESIGN:Prospective case-control study. PATIENT(S):In total, 24 women and men who became pregnant with twins, consecutively, and expected the...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2007.03.064
更新日期：2008-03-01 00:00:00
abstract：OBJECTIVE:To determine whether fallopian sperm perfusion significantly improves pregnancy rates over intrauterine insemination (IUI) in infertile patients. DESIGN:Prospective, randomized, controlled trial and metaanalysis of the literature. SETTING:University-based infertility practice. PATIENT(S):Patients undergoin...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章,meta分析,随机对照试验
doi：10.1016/s0015-0282(99)00068-0
更新日期：1999-05-01 00:00:00
abstract：:An improved knowledge of cryopreservation of primate embryos will have important research and clinical application. Fifty-six 4- to 8-cell in vitro fertilized embryos were frozen in HEPES-buffered Tyrode's solution containing 1.5 M dimethylsulfoxide (DMSO) and cooled at the rate of 0.3 degrees C/minute to -39 degrees ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)49225-3
更新日期：1986-03-01 00:00:00
abstract：OBJECTIVE:To assess the clinical relevance of daily hormonal changes for achieving a successful pregnancy in anovulatory infertile women. DESIGN:A comparative study of hormonal dynamics in pregnant and nonpregnant cycles during the pulsatile subcutaneous administration of hMG. Subjects received subcutaneous injection ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)56093-2
更新日期：1993-08-01 00:00:00
abstract：OBJECTIVE:To evaluate the association between genetic variants in Ser-Arg (SR) protein-coding genes and the susceptibility of nonobstructive azoospermia (NOA) in Chinese men. DESIGN:Case-control study. SETTING:State Key Laboratory of Reproductive Medicine in Nanjing Medical University conducted the genotyping and exa...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2014.02.033
更新日期：2014-06-01 00:00:00
abstract：:A new direct-to-consumer genetic test purports to detect fetal gender as early as five weeks of pregnancy. The availability of this test highlights the consequences of the current system of oversight for genetic tests and underscores the need for an enhanced regulatory framework to ensure the accuracy, reliability, an...
journal_title：Fertility and sterility
pub_type： 社论
doi：10.1016/j.fertnstert.2006.03.016
更新日期：2006-07-01 00:00:00
abstract：:Significant advances have been made in our understanding of ovarian dysfunction in polycystic ovary syndrome (PCOS), and alterations in adipose tissue function are likely to play an important role in its pathophysiology. This review highlights the principal novel concepts presented at the 4th special scientific meetin...
journal_title：Fertility and sterility
pub_type： 共识发展会议,杂志文章,评审
doi：10.1016/j.fertnstert.2009.03.058
更新日期：2010-07-01 00:00:00
abstract：OBJECTIVE:To assess knowledge and attitudes about infertility through a survey. DESIGN:Descriptive study with stratified random sampling. SETTING:Eighteen high schools were selected in Toronto, Ontario, Canada. PATIENT(S):Seven hundred seventy-two students participated in the study. The mean age of students was 17.5...
journal_title：Fertility and sterility
pub_type： 杂志文章,多中心研究
doi：10.1016/j.fertnstert.2007.10.024
更新日期：2008-12-01 00:00:00
abstract：:In young women receiving chemotherapy for Hodgkin's disease, the combined use of triptorelin and tibolone cotreatment may be a useful tool for preserving ovarian function because all but three (10%) of the women in this treatment group returned to spontaneous ovulation and menses, in contrast to 23% of subjects in the...
journal_title：Fertility and sterility
pub_type： 信件
doi：10.1016/j.fertnstert.2006.10.004
更新日期：2007-03-01 00:00:00
abstract：:Rabbits were immunized with homologous spermatozoa to investigate their autoimmunogenic nature. Major sperm autoantigens that elicit antisperm antibodies were analyzed molecularly by the sodium dodecylsulfate (SDS) gel/protein blot radioimmunobinding method. IgG fractions of the autoimmune sera were purified by a prot...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1984-01-01 00:00:00
abstract：OBJECTIVE:To investigate the localization of tenascin expression in the endometrium of women without endometriosis and in endometriotic implants, and to determine the in vitro regulation of tenascin by E(2) in these tissues. DESIGN:Experimental laboratory study. SETTING:University medical center. PATIENT(S):Reproduc...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2007.05.028
更新日期：2008-05-01 00:00:00
abstract：OBJECTIVE:To report a case of a methotrexate (MTX)-resistant heterotopic interstitial pregnancy in which dactinomycin was necessary as a second-line chemotherapy. DESIGN:Case report. SETTING:Medical college-affiliated hospital. PATIENT(S):A 39-year-old woman with vaginal bleeding after the transfer of two thawed 8-c...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.10.003
更新日期：2009-03-01 00:00:00
abstract：OBJECTIVE:To compare the psychological impact of recurrent pregnancy loss (RPL) on affected men and women and to determine risk and protective factors in both partners. DESIGN:Cross-sectional study. SETTING:University-affiliated fertility center. PATIENT(S):Ninety female/male couples and 14 women. INTERVENTION(S):P...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2020.08.1421
更新日期：2020-12-01 00:00:00
abstract：:Tamoxifen therapy in premenopausal women with breast cancer may be associated with the development of ovarian cysts. In this report, a case of ovarian torsion associated with TAM therapy is described. ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)55688-x
更新日期：1993-02-01 00:00:00
abstract：OBJECTIVE:To examine the relationship between an antibody against GAPDH-2, a sperm-specific protein, and infertility of female mice. DESIGN:Basic research. SETTING:National Research Institute for Family Planning Beijing, World Health Organization Collaboration Center of Human Reproduction. ANIMAL(S):New Zealand rabb...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.09.001
更新日期：2009-12-01 00:00:00
abstract：:Of 299 patients evaluated for infertility between July 1, 1974, and December 31, 1976, 21 (7.2%) became pregnant during the initial evaluation prior to any recognized therapy. A comparative analysis was made between these 21 couples and the 223 completely evaluated infertility couples. No significant difference in sex...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1978-07-01 00:00:00
abstract：:Women bear the predominant burden of our obesogenic environment, with a higher incidence of obesity than men, more impact on their fertility and success with treatment, and significant maternal and perinatal morbidity and mortality. In this series, the causes, consequences, and solutions regarding the obesity pandemic...
journal_title：Fertility and sterility
pub_type：
doi：10.1016/j.fertnstert.2017.02.110
更新日期：2017-04-01 00:00:00
abstract：:The Ericsson albumin filtration technique was used to collect a fraction rich in Y sperm for selective insemination in couples desiring a male infant. Of 35 conceptions in which sex was known at delivery or spontaneous abortion, there were 28 males (80%). Twelve pregnancies were achieved after separation of sperm in a...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1984-11-01 00:00:00
abstract：OBJECTIVE:To evaluate vaginal bleeding profiles with lower doses of conjugated equine estrogens (CEE) and medroxyprogesterone acetate (MPA) as continuous combined therapy. DESIGN:The Women's Health, Osteoporosis, Progestin, Estrogen (Women's HOPE) study, a randomized, double-blind, placebo-controlled trial. SETTING:S...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/s0015-0282(01)01792-7
更新日期：2001-06-01 00:00:00
abstract：:This Committee Opinion reviews the unresolved issues and experimental nature associated with the procedure and its limited success rates. ...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2008.08.033
更新日期：2008-11-01 00:00:00
abstract：:Heterologous antibodies have frequently been used to develop assays in other species. Human urinary LH kits, widely available for predicting the LH surge, offer a unique opportunity to determine the timing of ovulation and mating in nonhuman primates. We tested three commercially available ovulation predictor kits for...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)53301-9
更新日期：1990-02-01 00:00:00
abstract：OBJECTIVE:To examine the association between the midfollicular FSH-LH ratio and the number of follicles, and the multifollicular ovarian response to gonadotropin stimulation in patients with polycystic ovary syndrome (PCOS) with normal basal LH and FSH levels. SUBJECT(S):Eighteen patients who had an abandoned treatmen...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(97)80069-6
更新日期：1997-03-01 00:00:00
abstract：:Two hundred ten treatment cycles of follicle-stimulating hormone (FSH) or human menopausal gonadotropin (hMG) were completed in 49 patients with clomiphene citrate-resistant polycystic ovarian syndrome. The results from 68 cycles of daily intramuscular (IM) FSH and 41 cycles of IM hMG were compared. The ovulation rate...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)53511-0
更新日期：1990-05-01 00:00:00
abstract：OBJECTIVE:To assess the effects of estro-progestin supplementation on ghrelin-mediated GH release, we studied the consequence of ghrelin or saline injection before and after 60 days of hormone therapy or placebo administration in postmenopausal subjects. DESIGN:A prospective double blind, placebo-controlled, and paral...
journal_title：Fertility and sterility
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.fertnstert.2007.02.042
更新日期：2008-02-01 00:00:00
abstract：:Some see an "alarming inconsistency" in candidate-screening practices of assisted reproductive technology (ART) programs and call for common guidelines. However, reasonable people can disagree about who should be prevented from having children and why. ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2005.05.028
更新日期：2005-11-01 00:00:00
abstract：OBJECTIVE:To determine the relative efficacy of ultrasound-guided embryo transfer and embryo transfer by clinical touch alone. DESIGN:Systematic review and meta-analysis of randomized, controlled trials comparing ultrasound-guided embryo transfer with embryo transfer by clinical touch alone. SETTING:Infertility cente...
journal_title：Fertility and sterility
pub_type： 杂志文章,meta分析,评审
doi：10.1016/s0015-0282(03)01015-x
更新日期：2003-10-01 00:00:00
abstract：:The third annual meeting of the Androgen Excess Society, held in San Diego, California, June 3, 2005, reported on new developments in the field, including intrafollicular steroidogenesis, intrathecal biochemistry, mechanisms of insulin signal and resistance of polycystic ovary syndrome, and novel aspects of androgen s...
journal_title：Fertility and sterility
pub_type：
doi：10.1016/j.fertnstert.2006.06.049
更新日期：2006-11-01 00:00:00
abstract：:Effective contraception and easily available abortion have contributed to the decline of adoptable children. This decline has resulted in a marked increase in the demand for AID. The provider of donor semen must establish minimal semen criteria to meet this demand effectively. During the past 8 years the authors have ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)45923-6
更新日期：1981-12-01 00:00:00
