A meta-analysis of ultrasound-guided versus clinical touch embryo transfer.

Abstract:

OBJECTIVE:To determine the relative efficacy of ultrasound-guided embryo transfer and embryo transfer by clinical touch alone. DESIGN:Systematic review and meta-analysis of randomized, controlled trials comparing ultrasound-guided embryo transfer with embryo transfer by clinical touch alone. SETTING:Infertility centers providing treatment with in vitro fertilization/embryo transfer. PATIENT(S):Women undergoing embryo transfer. INTERVENTION(S):Embryo transfer with or without transabdominal ultrasound guidance. MAIN OUTCOME MEASURE(S):Clinical pregnancy rate and embryo implantation rate. RESULT(S):A total of eight prospective controlled trials were identified. Of these studies, four were nonrandomized or quasi-randomized and four were genuinely randomized. Meta-analysis demonstrated a significantly increased chance of clinical pregnancy following ultrasound-guided embryo transfer in all studies and in the genuinely randomized subgroup. The embryo implantation rate was also significantly increased following ultrasound-guided embryo transfer. CONCLUSION(S):Ultrasound-guided embryo transfer significantly increases the chance of clinical pregnancy and significantly increases the embryo implantation rate.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Buckett WM

doi

10.1016/s0015-0282(03)01015-x

keywords:

subject

Has Abstract

pub_date

2003-10-01 00:00:00

pages

1037-41

issue

4

eissn

0015-0282

issn

1556-5653

pii

S001502820301015X

journal_volume

80

pub_type

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