Hormonal treatment of functional ovarian cysts: a randomized, prospective study.

Abstract:

:Estrogen (E)/progestin therapy for functional ovarian cysts is widely used in clinical practice, but the efficacy of this treatment has not been determined in controlled trials. In this study, we examined the effect of E/progestin administration in a group of infertility patients enrolled in a program of ovulation induction who had cysts identified by transvaginal sonography. Patients were randomized to receive either norethindrone 1 mg/mestranol 0.05 mg/d (group A, n = 24) or no treatment (group B, n = 24) for up to 6 weeks. Patients were re-evaluated by sonography at 3, 6, and 9 weeks after entry into the protocol. The ages, mean cyst diameters, and proportions of patients having received gonadotropins in the previous menstrual cycle were not significantly different among the two groups. All patients who had a sonographic abnormality persisting for 9 weeks were surgically explored and found to have pathological cysts. The rate of disappearance of functional ovarian cysts was not affected by E/progestin treatment.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Steinkampf MP,Hammond KR,Blackwell RE

subject

Has Abstract

pub_date

1990-11-01 00:00:00

pages

775-7

issue

5

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(16)53930-2

journal_volume

54

pub_type

临床试验,杂志文章,随机对照试验
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    abstract::Although the technique of in vitro fertilization and embryo transfer (IVF-ET) was developed for couples with untreatable tubal factor infertility, IVF-ET is now being applied to women with other causes of infertility and normal pelvic anatomy. In an effort to determine the treatment-independent pregnancy rate, we retr...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)59114-6

    authors: Haney AF,Hughes CL Jr,Whitesides DB,Dodson WC

    更新日期:1987-04-01 00:00:00

  • Endometriosis and the development of tuboperitoneal fistulas after tubal ligation.

    abstract::The present study details gross and histologic findings of 79 previously ligated fallopian tubes from 3 groups of patients. Of 20 oviducts removed after documented sterilization failure (group I), 6 revealed a process compatible with endometriosis. Four of nine previously ligated fallopian tubes removed at the Johns H...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)45251-9

    authors: Rock JA,Parmley TH,King TM,Laufe LE,Su BS

    更新日期:1981-01-01 00:00:00

  • Presence of soluble b-type cytochrome in human seminal fluid.

    abstract::In 1951 it was shown that human spermatozoa contained cytochromes a, b, and c. It was noted that the cytochromes were confined to the sperm and were not found in seminal fluid. More recently we have observed in seminal plasma a soluble component that has a typical spectrum of a reduced cytochrome b, but can be disting...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:

    authors: Trifunac NP,Bernstein GS

    更新日期:1981-03-01 00:00:00

  • Comparison of characteristics of fibroids in African American and white women undergoing premenopausal hysterectomy.

    abstract:OBJECTIVE:To compare pathologic characteristics and epidemiologic risk factors for uterine fibroids in African American and white women undergoing hysterectomy. DESIGN:Cross-sectional analysis of women undergoing premenopausal hysterectomy. SETTING:Two university-associated hospitals in North Carolina. PATIENT(S):Af...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2012.10.039

    authors: Moorman PG,Leppert P,Myers ER,Wang F

    更新日期:2013-03-01 00:00:00

  • Is there a need to definitively diagnose the location of a pregnancy of unknown location? The case for "no".

    abstract::The ability to predict the outcome of a pregnancy of unknown location (PUL) has been extensively studied over the past decade. Between 8%-14% of PULs will develop into ectopic pregnancies (EP), and therefore the need to confirm pregnancy location is not without good reason. Strategies to predict EP in the PUL populati...

    journal_title:Fertility and sterility

    pub_type: 评论,杂志文章

    doi:10.1016/j.fertnstert.2012.09.032

    authors: Reid S,Condous G

    更新日期:2012-11-01 00:00:00

  • Ovarian preservation in a young patient with Gorlin syndrome and multiple bilateral ovarian masses.

    abstract:OBJECTIVE:To report a case of bilateral ovarian fibromas and ovarian leiomyomas in a young patient with Gorlin syndrome and to highlight issues of fertility preservation, ovarian conservation, and preimplantation genetic diagnosis in this population. DESIGN:Case report. SETTING:University hospital. PATIENT(S):A 15-y...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2011.04.028

    authors: Morse CB,McLaren JF,Roy D,Siegelman ES,Livolsi VA,Gracia CR

    更新日期:2011-07-01 00:00:00

  • How do patients choose private in vitro fertilization treatment? A customer survey in a tertiary fertility center in the United Kingdom.

    abstract:OBJECTIVE:To assess the relevant factors affecting patients' decision when choosing a clinic for private, self-funded IVF treatment. DESIGN:Prospective anonymous closed questionnaires. SETTING:Single tertiary-care private IVF center. PATIENT(S):New patients attending primary consultation in a period of 7 months from...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(01)01751-4

    authors: Lass A,Brinsden P

    更新日期:2001-05-01 00:00:00

  • Sequential use of clomiphene citrate, human menopausal gonadotropin, and human chorionic gonadotropin in human in vitro fertilization. I. Follicular growth and oocyte suitability.

    abstract::Sequential treatment with clomiphene citrate, human menopausal gonadotropin, and human chorionic gonadotropin was successfully applied to 149 women in the framework of an in vitro fertilization and embryo transfer program and led to the birth of normal children. An average of 3.5 follicles was promoted at each cycle. ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)48382-2

    authors: Plachot M,Mandelbaum J,Cohen JJ,Debache C,Pigeau F,Junca AM

    更新日期:1985-02-01 00:00:00

  • Ectopic twin pregnancy in cesarean scar after in vitro fertilization/embryo transfer: case report.

    abstract:OBJECTIVE:To present two cases of ectopic twin pregnancy in a Cesarean section scar following IVF-embryo transfer. DESIGN:Case report. SETTING:Tertiary referral case center. PATIENT(S):Two women who had ectopic twin pregnancy in a Cesarean section scar, in both cases following IVF and embryo transfer. INTERVENTION(...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2007.11.091

    authors: Chueh HY,Cheng PJ,Wang CW,Shaw SW,Lee CL,Soong YK

    更新日期:2008-11-01 00:00:00

  • Dynamics of the development of multiple follicles during ovarian stimulation for in vitro fertilization using recombinant follicle-stimulating hormone (Puregon) and various doses of the gonadotropin-releasing hormone antagonist ganirelix (Orgalutran/Antag

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    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0015-0282(00)01789-1

    authors: de Jong D,Macklon NS,Eijkemans MJ,Mannaerts BM,Coelingh Bennink HJ,Fauser BC,Ganirelix Dose-Finding Study Group.

    更新日期:2001-04-01 00:00:00

  • Improved clinical outcomes for in vitro fertilization with delay of embryo transfer from 48 to 72 hours after oocyte retrieval: use of glucose- and phosphate-free media.

    abstract:OBJECTIVE:To evaluate clinical outcomes of day 2 versus day 3 ET using a culture media with no glucose or phosphate. DESIGN:Retrospective clinical study. SETTING:Hospital-based fertility clinic. PATIENT(S):One hundred seventy-six IVF-ET patients undergoing controlled ovarian supraovulation. INTERVENTION(S):IVF and ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(97)00499-8

    authors: Carrillo AJ,Lane B,Pridman DD,Risch PP,Pool TB,Silverman IH,Cook CL

    更新日期:1998-02-01 00:00:00

  • Congenital interruption of the ampullary portion of the fallopian tube.

    abstract::We present a rare case of a congenital isolated missing segment of the fallopian tube, including hysterosalpingographic and laparoscopic images. We conclude that when this occurs without concomitant müllerian anomalies, the mechanism of development would not be expected to be associated with an increase in renal abnor...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2006.01.012

    authors: Dahan MH,Burney R,Lathi R

    更新日期:2006-06-01 00:00:00

  • Key lipogenic gene expression can be decreased by estrogen in human adipose tissue.

    abstract:OBJECTIVE:To characterize the molecular mechanisms by which estrogens reduce adipose tissue mass, with particular focus on genes involved in lipogenesis. DESIGN:This study involves one arm of an open randomized clinical study with parallel group comparison. SETTING:Women's health clinical research unit at a universit...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.fertnstert.2007.06.011

    authors: Lundholm L,Zang H,Hirschberg AL,Gustafsson JA,Arner P,Dahlman-Wright K

    更新日期:2008-07-01 00:00:00

  • Creation of a neovagina following Williams vaginoplasty and the Creatsas modification in 111 patients with Mayer-Rokitansky-Küster-Hauser syndrome.

    abstract:OBJECTIVE:Evaluation of the Creatsas modification of Williams vaginoplasty for the creation of neovagina in patients with Mayer-Rokitansky-Küster-Hauser syndrome (MRKH syndrome). DESIGN:Record of perioperative and postoperative results and complications. Follow-up evaluations of patients yearly after the operation. S...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(01)02836-9

    authors: Creatsas G,Deligeoroglou E,Makrakis E,Kontoravdis A,Papadimitriou L

    更新日期:2001-11-01 00:00:00

  • Preclinical abortions and endometriosis.

    abstract::A single human chorionic gonadotropin determination was performed in 786 infertile women during the late luteal phase to determine the frequencies of preclinical abortions and whether the frequency was increased in women with endometriosis. Thirty-seven pregnancies (4.7% of cycles) were identified, of which six were c...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)59705-2

    authors: Pittaway DE,Ellington CP,Klimek M

    更新日期:1988-02-01 00:00:00

  • A rare case of extrauterine adenosarcoma arising in endometriosis of the rectovaginal septum.

    abstract:OBJECTIVE:To present a rare case of endometrial stromal sarcoma arising in endometriosis of the rectovaginal septum. DESIGN:Case report. SETTING:Academic tertiary referral center for endometriosis treatment. PATIENT(S):A 50-year-old woman with a history of endometriosis presented with catamenial rectal pain and deep...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2003.09.053

    authors: Raffaelli R,Piazzola E,Zanconato G,Fedele L

    更新日期:2004-04-01 00:00:00

  • Comparison of techniques for the selection of bacteria-free sperm preparations.

    abstract::The authors compared the three most commonly used sperm preparation techniques--swim-up, fall-down, and Percoll gradient--for their ability to recover highly motile sperm and minimize bacterial contamination. Eleven human semen samples collected by masturbation were used and run in parallel with the three methods. A s...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)59481-3

    authors: Sun LS,Gastaldi C,Peterson EM,de la Maza LM,Stone SC

    更新日期:1987-10-01 00:00:00

  • Interruption of pregnancy by prostaglandin 15-methyl F2alpha.

    abstract::The current study was formulated to investigate the abortifacient activity of prostaglandin 15-methyl F2alpha (15-methyl PGF2alpha) administered intramuscularly to 80 healthy women with gestations between 8 and 22 weeks. Goals were the establishment of an effective dosage schedule and assessment of the incidence and s...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:

    authors: Bolognese RJ,Corson SL

    更新日期:1975-07-01 00:00:00

  • Effect of baseline ovarian cysts on in vitro fertilization and gamete intrafallopian transfer cycles.

    abstract::The presence of ovarian cysts may compromise the success of in vitro fertilization (IVF) and gamete intrafallopian transfer (GIFT). We prospectively studied 212 consecutive ovulation induction cycles in 120 patients for IVF and/or GIFT. A baseline cyst was defined as any intraovarian cystic structure greater than or e...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)54123-5

    authors: Goldberg JM,Miller FA,Friedman CI,Dodds WG,Kim MH

    更新日期:1991-02-01 00:00:00

  • Development of a rapid, sensitive, and reproducible laboratory test kit for the assessment of plasma membrane integrity of human sperm.

    abstract:OBJECTIVE:To develop a rapid, sensitive, and reproducible hypoosmotic swelling test kit for the assessment of plasma membrane integrity of human sperm in vitro. DESIGN:Prospective comparison of results with the World Health Organization (WHO) method, performed simultaneously. SETTING:Infertility center in a major cit...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2007.02.003

    authors: Misro MM,Chaki SP

    更新日期:2008-01-01 00:00:00

  • Low-dose aspirin in reproductive health: effects on menstrual cycle characteristics.

    abstract:OBJECTIVE:To estimate the effect of daily 81 mg low-dose aspirin (LDA) on menstrual cycle length and hormone profiles. DESIGN:Secondary analysis of a trial evaluating the effect of daily LDA or placebo on live birth among women with one or two previous pregnancy losses. SETTING:University medical centers. PATIENT(S)...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2020.06.022

    authors: Evans MB,Nobles CJ,Kim K,Hill MJ,DeCherney AH,Silver RM,Mumford SL,Sjaarda LA,Perkins NJ,Schisterman EF

    更新日期:2020-12-01 00:00:00

  • Effects of pentoxifylline on human sperm motility in normospermic individuals using computer-assisted analysis.

    abstract:OBJECTIVE:To determine if pentoxifylline has an in vitro effect on human sperm motility in subjects with normal semen analysis. DESIGN:Prospective, longitudinal study of the effect of pentoxifylline on normospermic semen samples using computerized analysis. SETTING:The Assisted Conception Unit, Royal Maternity Hospit...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)55708-2

    authors: Lewis SE,Moohan JM,Thompson W

    更新日期:1993-02-01 00:00:00

  • Strategies for disclosure: how parents approach telling their children that they were conceived with donor gametes.

    abstract:OBJECTIVE:To describe how parents envision, plan, and enact disclosing to their children that they were conceived with donor gametes. DESIGN:In-depth ethnographic interviews. SETTING:Participants were recruited from 11 medical infertility practices and 1 sperm bank in Northern California. PATIENT(S):A total of 141 m...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2006.07.1514

    authors: Mac Dougall K,Becker G,Scheib JE,Nachtigall RD

    更新日期:2007-03-01 00:00:00

  • Presence of messenger ribonucleic acid for epidermal growth factor (EGF) and EGF receptor demonstrable in monolayer cell cultures of myometria and leiomyomata.

    abstract::There is a paucity of data concerning the factors involved in the growth of uterine leiomyomata. The expression of mRNAs encoding EGF and the EGF receptor in myometrial and leiomyoma cultures suggest that EGF may be involved in the autocrine/paracrine regulation of human uterine leiomyomata and myometrial growth. ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)54681-0

    authors: Yeh J,Rein M,Nowak R

    更新日期:1991-11-01 00:00:00

  • Gel instillation sonohysterography: first experience with a new technique.

    abstract:OBJECTIVE:A practical attempt to simplify and improve the technique of artificial uterine cavity distension by instilling gel instead of flushing saline. DESIGN:Prospective observational study. SETTING:Teaching hospital. PATIENT(S):One hundred twenty patients with an indication for sonohysterography (abnormal uterin...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2006.05.075

    authors: Exalto N,Stappers C,van Raamsdonk LA,Emanuel MH

    更新日期:2007-01-01 00:00:00

  • Contrast infusion sonography to assess microinsert placement and tubal occlusion after Essure.

    abstract:OBJECTIVE:To develop a technique for contrast infusion sonography and assess the possible use in determining microinsert placement and tubal status after Essure sterilization. DESIGN:Techniques and instrumentation. SETTING:Healthy women in an academic multispecialty group. PATIENT(S):Ten women desiring permanent ste...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.fertnstert.2005.10.075

    authors: Connor VF

    更新日期:2006-06-01 00:00:00

  • Blepharophimosis-ptosis-epicanthus inversus syndrome and hypergonadotropic hypogonadism.

    abstract:OBJECTIVE:To describe a woman with blepharophimosis-ptosis-epicanthus inversus syndrome and hypergonadotropic hypogonadism. DESIGN:Case report. SETTING:University medical center. PATIENT(S):One 25-year-old woman. INTERVENTION(S):Pedigree, hormone assays, and donor embryo transfer. MAIN OUTCOME MEASURE(S):Pregnancy...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2008.07.1763

    authors: Siewert AL,Stein Q,Flanagan J,Hansen KA

    更新日期:2008-11-01 00:00:00

  • Results of artificial insemination at home by the partner with cryopreserved donor semen: a randomized study.

    abstract::The use of cryopreserved semen offers the possibility of home insemination by the instructed partner. A comparative study was designed whereby participants were randomly allocated to use home or clinic insemination for six cycles. If no pregnancy had occurred after six cycles, the site of insemination was switched to ...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0015-0282(16)59956-7

    authors: Hogerzeil HV,Hamerlynck JV,van Amstel N,Nagelkerke NJ,Lammes FB

    更新日期:1988-06-01 00:00:00

  • Placental protein 14 levels in uterine flushing and plasma of women with unexplained infertility.

    abstract:OBJECTIVES:To measure concentrations of placental protein 14 (PP14) in uterine flushings and plasma samples obtained from patients with unexplained infertility and to compare the results of those of normal fertile women. DESIGN:Prospective study. SETTING:Infertility and gynaecology outpatient clinics at the Jessop Ho...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)55803-8

    authors: Mackenna A,Li TC,Dalton C,Bolton A,Cooke I

    更新日期:1993-03-01 00:00:00

  • Effects of pH on the migration of X and Y sperm.

    abstract::A study was undertaken to examine the influence of pH on the migration of X and Y sperm as observed in freshly ejaculated semen samples from human donors. These sperm were allowed to migrate into capillary tubes containing media of varying pH. Y-carrying sperm were i dentified using flourescent staining with quinacr...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)38224-3

    authors: Diasio RB,Glass RH

    更新日期:1971-05-01 00:00:00