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Ovarian preservation in a young patient with Gorlin syndrome and multiple bilateral ovarian masses.

Abstract：

OBJECTIVE:To report a case of bilateral ovarian fibromas and ovarian leiomyomas in a young patient with Gorlin syndrome and to highlight issues of fertility preservation, ovarian conservation, and preimplantation genetic diagnosis in this population. DESIGN:Case report. SETTING:University hospital. PATIENT(S):A 15-year-old female patient with Gorlin syndrome and bilateral ovarian masses. INTERVENTION(S):Ultrasound, magnetic resonance imaging, hormone analysis, and laparotomy with resection of ovarian fibromas. MAIN OUTCOME MEASURE(S):Preservation of ovarian function, pathologic diagnosis. RESULT(S):Our patient represented an adolescent case of bilateral ovarian fibromas and leiomyomas in Gorlin syndrome presenting with menstrual irregularities. She was managed surgically with resection of the lesions and conservation of normal ovarian tissue. CONCLUSION(S):In Gorlin syndrome, ovarian fibromas are a common clinical manifestation. Patients with ovarian involvement may present with complex gynecologic needs and may have decreased fertility potential. Careful surgical management, follow-up, and counseling on options for future fertility should be offered to all patients.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Morse CB,McLaren JF,Roy D,Siegelman ES,Livolsi VA,Gracia CR

doi

10.1016/j.fertnstert.2011.04.028

subject

Has Abstract

pub_date

2011-07-01 00:00:00

pages

e47-50

issue

1

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(11)00639-X

journal_volume

96

pub_type

杂志文章

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