Abstract：
OBJECTIVE:To determine whether high ligation is an effective treatment for infertile men with clinical varicocele. DESIGN:A randomized, controlled trial of high spermatic vein ligation was carried out. The patients were treated and observed for 3 years. SETTING:Infertility treatment clinic and andrology laboratory in a hospital. PATIENTS:Infertile men with abnormal semen analysis because of varicocele only. INTERVENTION:High ligation 1 year postrecruitment (group A) and at the beginning of the study (group B). RESULTS:Among the 20 couples in group A, 2 pregnancies (10%) were achieved within the 1st year of observation period. During the year after high ligation, there were 8 pregnancies (44.4%), and during the 2nd year after high ligation, there were 4 more pregnancies (22.2%). In group B, 15 pregnancies (60%) occurred within the 1st year after operation. Three pregnancies (12%) and 1 pregnancy (4%) occurred during the 2nd and 3rd year, respectively. After operation in all patients of both groups, there was significant improvement in semen parameters, regardless of pregnancy occurrence. The difference in pregnancy rate (PR) between the operated group B and nonoperated group A during the 1st year of study was found to be highly significant. CONCLUSIONS:It is concluded that in a population of infertile men presenting varicocele as the only demonstrable factor of infertility, the varicocele is clearly associated with infertility and reduced testicular function, and its correction by ligation improves sperm parameters and fertility rate. Furthermore, the highest PR in both groups occurred during the 1st year postoperation.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Madgar I,Weissenberg R,Lunenfeld B,Karasik A,Goldwasser Bdoi
10.1016/s0015-0282(16)57306-3subject
Has Abstractpub_date
1995-01-01 00:00:00pages
120-4issue
1eissn
0015-0282issn
1556-5653pii
S0015-0282(16)57306-3journal_volume
63pub_type
临床试验,杂志文章,多中心研究,随机对照试验abstract：OBJECTIVE:To report an unusual case of embryo implantation and superfetation. DESIGN:Retrospective case analysis. SETTING:Oak Brook Fertility Center. PATIENT(S):A 41-year-old woman underwent two consecutive ovarian stimulation cycles interrupted by a normal menstrual period. Ovulation and implantation occurred durin...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(97)00244-6
更新日期：1997-09-01 00:00:00
abstract：OBJECTIVE:To investigate the association between several factors such as demographics, personal habits, reproductive factors, menstrual characteristics, contraception, and clinical profile and the probability of having endometriosis. SETTING:Ten clinical institutions in the Montreal area. PATIENT(S):A total of 2777 s...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2003.10.038
更新日期：2004-06-01 00:00:00
abstract：OBJECTIVE:To evaluate the changes of pain symptoms induced by buserelin acetate, a gonadotropin-releasing hormone agonist, in a group of patients with endometriosis. DESIGN:Thirty-five infertile patients with one or more of the following symptoms (dysmenorrhea, pelvic pain, deep dyspareunia, and endometriosis stage I ...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0015-0282(16)55792-6
更新日期：1993-03-01 00:00:00
abstract：:Significant advances have been made in our understanding of ovarian dysfunction in polycystic ovary syndrome (PCOS), and alterations in adipose tissue function are likely to play an important role in its pathophysiology. This review highlights the principal novel concepts presented at the 4th special scientific meetin...
journal_title：Fertility and sterility
pub_type： 共识发展会议,杂志文章,评审
doi：10.1016/j.fertnstert.2009.03.058
更新日期：2010-07-01 00:00:00
abstract：OBJECTIVE:To compare histologically and stereologically the endometriotic nodule of the rectovaginal septum to peritoneal endometriosis. DESIGN:Morphometric investigation, cytokeratin and vimentin content, and steroid receptor evaluation were performed on endometriotic tissue from the peritoneum (n = 52) and rectovagi...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
abstract：:Serum prolactin was studied in 25 fertile and 127 infertile men. The latter included 91 oligospermic, 27 azoospermic, and 9 hypogonadotropic hypogonadal men. The mean prolactin level in all three groups of infertile men was significantly above that of the fertile group. There was no correlation among serum levels of f...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)42259-4
更新日期：1976-12-01 00:00:00
abstract：:The relaxin content of 92 normal semen samples and 85 semen samples selected at random was correlated to the parameters measured on routine semen analysis in those samples. The concentration of immunoactive relaxin in a sample of semen plasma did not correlate with any of the parameters commonly used for semen analysi...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)59130-4
更新日期：1987-04-01 00:00:00
abstract：OBJECTIVE:To introduce an effective approach for excision of ovarian endometrioma by "water injection"-assisted laparoscopy treatment. DESIGN:Step-by-step video explanation of the surgical procedure with still pictures and surgical video clips to demonstrate the detailed technique, approved by the Shengjing Hospital o...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2019.05.014
更新日期：2019-09-01 00:00:00
abstract：OBJECTIVE:To evaluate the efficacy of blastocyst culture and transfer in human in vitro fertilization (IVF) as compared to day 3 embryo transfer. DESIGN:Prospective randomized trial. SETTING:Private assisted reproduction unit. PATIENT(S):A total of 162 IVF patients were included in the day 3 embryo transfer (n = 82)...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0015-0282(01)02939-9
更新日期：2002-01-01 00:00:00
abstract：:In this observational, case-control study in infertile women, we observed elevated serum oxidative stress that was significantly correlated with an increase in serum paraoxonase-1 activity and without any evidence of a proinflammatory reaction. These results suggest a protective role of paraoxonase-1 against inflammat...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2009.11.043
更新日期：2010-08-01 00:00:00
abstract：INTRODUCTION:Polycystic ovary syndrome (PCOS) is a highly prevalent disorder among postmenarcheal premenopausal women, accounting for much of anovulatory infertility, and it is associated with several comorbidities. The natural history of PCOS, as well as hypotheses regarding its etiology, facilitates employment of the...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2005.09.066
更新日期：2006-07-01 00:00:00
abstract：OBJECTIVE:To assess the efficacy of tibolone add-back therapy with Goserelin treatment of uterine fibroids. DESIGN:Randomized placebo-controlled study. SETTING:Gynecology department of an inner-city teaching hospital. PATIENT(S):Seventy-five women of reproductive age with uterine fibroids. INTERVENTION(S):All women...
journal_title：Fertility and sterility
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.fertnstert.2007.02.064
更新日期：2008-02-01 00:00:00
abstract：OBJECTIVE:To develop a technique for contrast infusion sonography and assess the possible use in determining microinsert placement and tubal status after Essure sterilization. DESIGN:Techniques and instrumentation. SETTING:Healthy women in an academic multispecialty group. PATIENT(S):Ten women desiring permanent ste...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/j.fertnstert.2005.10.075
更新日期：2006-06-01 00:00:00
abstract：OBJECTIVE:To elucidate reinitiation factors in human spermatozoa preserved in the electrolyte-free solution at 4 degrees C. SETTING:Andrology laboratory of our hospital. PATIENTS:Semen samples were obtained from patients attending our infertility clinic. INTERVENTIONS:Ejaculated sperm were centrifuged and washed usi...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)58341-1
更新日期：1996-06-01 00:00:00
abstract：:Specialist training in reproductive medicine within Europe continues to evolve. Recent revisions, updates, and initiatives have helped to refine the core educational needs for the specialist trainee. ...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2015.05.025
更新日期：2015-07-01 00:00:00
abstract：:Mild-stimulation protocols with in vitro fertilization (IVF) generally aim to use less medication than conventional IVF. This guideline evaluates pregnancy and live-birth rates in patients expected to be poor responders using mild ovarian stimulation and natural-cycle protocols vs conventional IVF. ...
journal_title：Fertility and sterility
pub_type： 杂志文章,实务指引
doi：10.1016/j.fertnstert.2018.03.019
更新日期：2018-06-01 00:00:00
abstract：OBJECTIVE:To determine whether reactive oxygen species in peritoneal fluid might be a factor in infertility. DESIGN:Prospective study. SETTING:Andrology laboratory and gynecology clinic at a tertiary care facility. PATIENT(S):Women with endometriosis (n = 15) or idiopathic infertility (n = 11) who underwent laparosc...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(97)00343-9
更新日期：1997-11-01 00:00:00
abstract：OBJECTIVE:To report the case of a patient submitted to laparoscopic bowel resection in whom histology revealed endometriosis and schistosomiasis. DESIGN:Case report. SETTING:Multidisciplinary group practice and teaching hospital. PATIENT(S):A 31-year-old patient with pelvic pain. INTERVENTION(S):Laparoscopic bowel ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2005.08.068
更新日期：2006-04-01 00:00:00
abstract：:A new flexible protocol for the induction of recipient endometrial cycles is presented. For stimulation of endometrial growth, a fixed dose of conjugated estrogens, 3.75 mg/d was employed. The duration of the proliferative phase varied from 9 to 14 days, thus being adjusted to match the length of the follicular phase ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)60988-3
更新日期：1989-10-01 00:00:00
abstract：OBJECTIVE:To describe a woman with blepharophimosis-ptosis-epicanthus inversus syndrome and hypergonadotropic hypogonadism. DESIGN:Case report. SETTING:University medical center. PATIENT(S):One 25-year-old woman. INTERVENTION(S):Pedigree, hormone assays, and donor embryo transfer. MAIN OUTCOME MEASURE(S):Pregnancy...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.07.1763
更新日期：2008-11-01 00:00:00
abstract：:Direct effects of a gonadotropin-releasing hormone agonist (GnRHa), danazol, or estrogen/progestogen (E/P) on experimental endometriosis were evaluated in castrated female rats. Endometrial explants decreased in size following castration, but there was no further change in the treatment groups. Histologic examination ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)59727-1
更新日期：1988-02-01 00:00:00
abstract：OBJECTIVE:To evaluate, using the hemizona assay (HZA), whether egg yolk treatment of human sperm enhances binding to the human zona pellucida in vitro and to determine whether such a treatment is as efficient as the standard swim-up procedure for promoting sperm binding ability. DESIGN:Ejaculates were divided into ali...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)55261-3
更新日期：1992-09-01 00:00:00
abstract：OBJECTIVE:To study the changes that occur in vascular resistance to flow in the utero-ovarian circulation and their correlation with the number of follicles and steroid hormone levels in patients undergoing ovarian stimulation with gonadotropin. DESIGN:In a prospective study, the impedance to flow in the intraovarian ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)55853-1
更新日期：1993-04-01 00:00:00
abstract：:U. urealyticum with 15.8% and C. trachomatis antibodies with 15.4% were the most prevalent microbiological findings in 209 male infertility patients. The inflammatory marker granulocyte-elastase was significantly increased in men with C. trachomatis; these men also showed significantly decreased citric acid levels ind...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)54318-0
更新日期：1991-05-01 00:00:00
abstract：OBJECTIVE:To develop a consensus on the diagnostic criteria for chronic endometritis (CE) at hysteroscopy (HSC), and to evaluate these proposed criteria in a randomized-controlled observer study. DESIGN:Systematic review of studies evaluating the diagnostic accuracy of HSC in CE diagnosis; Delphi consensus on hysteros...
journal_title：Fertility and sterility
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.fertnstert.2019.03.004
更新日期：2019-07-01 00:00:00
abstract：:The effects of estradiol (E2) administered by a transdermal system on the induction of hypothalamic opioid activity was examined in 18 postmenopausal women. Women were given 25, 50, 100, or 200 micrograms/d dosages of E2 for 28 days each. Naloxone at a dosage of 2 mg/h was infused intravenously for 4 hours, and serum ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1991-04-01 00:00:00
abstract：:A couple may be considered to have fertility problems if they have been trying to conceive for over 1 year with no success. Worldwide, the inability to have children affects 10% to 15% of all couples. Subfertility can be divided into either male or female factor, or both partners can be affected. However, for some cou...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2018.05.028
更新日期：2018-09-01 00:00:00
abstract：OBJECTIVE:To evaluate whether the use of theophylline improves sperm motility and treatment outcome in frozen-thawed testicular sperm extraction (TESE). DESIGN:Artificial sperm activation was offered to azoospermic patients between January and October 2010 in two different centers (identical lab conditions). SETTING:...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2011.08.041
更新日期：2011-12-01 00:00:00
abstract：OBJECTIVE:To determine whether a history of prior cesarean delivery (CD) makes ET more difficult and impacts pregnancy outcomes. DESIGN:Prospective cohort study. SETTING:Tertiary care military facility. PATIENT(S):One hundred ninety-four patients with previous delivery undergoing IVF/intracytoplasmic sperm injection...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2016.03.045
更新日期：2016-08-01 00:00:00
abstract：OBJECTIVE:To compare pathologic characteristics and epidemiologic risk factors for uterine fibroids in African American and white women undergoing hysterectomy. DESIGN:Cross-sectional analysis of women undergoing premenopausal hysterectomy. SETTING:Two university-associated hospitals in North Carolina. PATIENT(S):Af...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2012.10.039
更新日期：2013-03-01 00:00:00
