Occurrence of a spontaneous luteinizing hormone surge in superovulated cycles--predictive value of serum progesterone.

Abstract:

:A preovulatory increase in serum progesterone (P) precedes the occurrence of an endogenous luteinizing hormone (LH) surge in a majority of women. This study evaluates whether a single daily measurement of serum P could reliably identify a spontaneous LH surge in women undergoing controlled ovarian hyperstimulation. Eighty-four infertile women received either clomiphene citrate and human menopausal gonadotropin (hMG), or hMG alone. Serum P levels were increased significantly the morning of the day of an endogenous LH surge (P less than 0.01). A 2-fold rise in the serum P levels was associated with a predictability of 64.4% of a LH surge; however, a 4-fold increase in serum P could accurately predict a spontaneous endogenous LH discharge in 93.3% (P less than 0.001) of cases.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Serafini P,Stone B,Kerin J,Batzofin J,Quinn P,Marrs RP

doi

10.1016/s0015-0282(16)59654-x

subject

Has Abstract

pub_date

1988-01-01 00:00:00

pages

86-9

issue

1

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(16)59654-X

journal_volume

49

pub_type

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