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Prospective, randomized trial of metformin and vitamins for the reduction of plasma homocysteine in insulin-resistant polycystic ovary syndrome.

Abstract：

:One hundred and two women with insulin-resistant polycystic ovary syndrome were randomized to treatment with a vitamin B preparation, metformin, or both, in conjunction with standard infertility treatment. Plasma homocysteine levels were significantly reduced by both B vitamins and metformin, but to a greater degree by B vitamins, and higher pregnancy rates were associated with vitamin B treatment.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Schachter M,Raziel A,Strassburger D,Rotem C,Ron-El R,Friedler S

doi

10.1016/j.fertnstert.2006.11.071

subject

Has Abstract

pub_date

2007-07-01 00:00:00

pages

227-30

issue

1

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(06)04569-9

journal_volume

88

pub_type

杂志文章,随机对照试验

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