Abstract:
OBJECTIVE:To determine a possible cyclic change in the concentration of glucose and fructose in the aqueous phase of human cervical mucus (CM). DESIGN:Concentrations of glucose and fructose were longitudinally determined in the aqueous phase of CM of normal cycling women using enzymatic techniques, modified for small quantities. SETTING:Patients visiting a fertility clinic were selected. PATIENTS:Nine healthy women with regular menstrual cycles of 28 +/- 3 days that appeared to be ovulatory, demonstrated by sonographic follicle immaging and serum progesterone (P) measurements. INTERVENTIONS:Cervical mucus samples were longitudinally collected preovulatory, postovulatory, and premenstrual in ovulatory cycles, monitored by ultrasound and blood estradiol and P measurements. MAIN OUTCOME MEASURES:The study was designed to measure glucose and fructose longitudinally on three different points during one cycle. RESULTS:The preovulatory glucose concentrations in CM were lower than postovulatory and premenstrual. The preovulatory fructose concentrations were lower than premenstrual. The glucose concentration correlated with the blood P level. CONCLUSION:There is a consistent change in the glucose concentration measured in human CM in three phases of the menstrual cycle. The preovulatory and premenstrual fructose concentrations differ significantly. Knowledge of the carbohydrate metabolism in human cervical mucus may contribute in illuminating the possible role of the carbohydrate metabolism in sperm migration at midcycle and implantation in the luteal phase.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
van der Linden PJ,Kets M,Gimpel JA,Wiegerinck MAdoi
10.1016/s0015-0282(16)54902-4subject
Has Abstractpub_date
1992-03-01 00:00:00pages
573-7issue
3eissn
0015-0282issn
1556-5653pii
S0015-0282(16)54902-4journal_volume
57pub_type
杂志文章abstract:OBJECTIVE:To determine the impact of a cryopreservation program on pregnancy rates and multiple-pregnancy rates in ART cycles. DESIGN:Retrospective study. SETTING:University teaching hospital. PATIENT(S):Women who underwent stimulation for in vitro fertilization at the Jones Institute for Reproductive Medicine betwe...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(00)01661-7
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:To confirm the advantages of goserelin prior to endometrial ablation for the treatment of dysfunctional uterine bleeding. DESIGN:Multicenter, prospective, randomized, double-blind study. PATIENT(S):Cycling premenopausal women with dysfunctional uterine bleeding. TREATMENT:Patients were randomized to gosere...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:1997-07-01 00:00:00
abstract::The association between educational level and cycle outcomes was quantified by applying multivariable logistic and linear regression within a prospective cohort of 2,569 women commencing their first in vitro fertilization (IVF) cycle. Although a woman's educational attainment was not associated with the likelihood of ...
journal_title:Fertility and sterility
pub_type: 杂志文章,多中心研究
doi:10.1016/j.fertnstert.2011.05.015
更新日期:2011-06-30 00:00:00
abstract:OBJECTIVE:To evaluate the occurrence of mutations of 5alpha-reductase type 2 gene in patients with cryptorchidism or idiopathic azoospermia. DESIGN:Controlled clinical study. SETTING:Yamagata University Hospital, Yamagata and Tokyo Electric Power Company Hospital, Tokyo, Japan. PATIENT(S):Patients with isolated cryp...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章
doi:10.1016/s0015-0282(02)03220-x
更新日期:2002-08-01 00:00:00
abstract:OBJECTIVE:To determine the prevalence of idiopathic hirsutism among a population of consecutive hirsute patients. DESIGN:Prospective cohort study. SETTING:University-based clinic. PATIENT(S):Premenopausal women with a complaint of hirsutism who were not receiving hormonal therapy. INTERVENTION(S):Evaluations for to...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(98)00141-1
更新日期:1998-08-01 00:00:00
abstract::One hundred four consecutive men who underwent a semen analysis as part of their infertility evaluation were assayed for sperm-associated immunoglobulin (Ig) and the third component of complement (C3). Sixteen (15%) of the 104 men had increased IgG, and 10 (12%) of 86 men tested had increased IgA on their sperm; howev...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1983-04-01 00:00:00
abstract::Osteoporosis continues to be a major public health challenge in both women and men. There are more than 2 million low-impact fractures in the United States every year, 39% of which occur in men. The mortality rate in the first year after hip fracture is estimated at 20% to 25% in women and is even higher in men. The g...
journal_title:Fertility and sterility
pub_type:
doi:10.1016/j.fertnstert.2019.10.004
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVE:To review existing scientific data related to the biology of estrogen in the aging process of women, and to understand the pharmacology, physiology, and diversity of sex hormones. DESIGN:A MEDLINE computer search was performed to identify relevant articles. RESULT(S):Estrogen and progesterone have been pres...
journal_title:Fertility and sterility
pub_type: 历史文章,杂志文章,评审
doi:10.1016/j.fertnstert.2003.10.052
更新日期:2004-06-01 00:00:00
abstract::A recent survey of American Society for Reproductive Medicine (ASRM) members indicates that they express a commitment to professional standards and a desire for advocacy. Their attitudes echo traditional values of professionalism, upon which ASRM should capitalize. ...
journal_title:Fertility and sterility
pub_type: 评论,杂志文章
doi:10.1016/j.fertnstert.2004.01.052
更新日期:2004-09-01 00:00:00
abstract::Cosmetics contain a vast number of chemicals, most of which are not under the regulatory purview of the Food and Drug Administration. Only a few of these chemicals have been evaluated for potential deleterious health impact: parabens, phthalates, polycyclic aromatic hydrocarbons, and siloxanes. A review of the ingredi...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/j.fertnstert.2016.08.020
更新日期:2016-09-15 00:00:00
abstract:OBJECTIVE:To assess associations between lifetime sexual assault and childlessness in female veterans. DESIGN:Cross-sectional, computer-assisted telephone interview study. SETTING:Two Midwestern Veterans Administration (VA) medical centers. PATIENT(S):A total of 1,004 women aged ≤52 years, VA-enrolled between 2000 a...
journal_title:Fertility and sterility
pub_type: 杂志文章,多中心研究
doi:10.1016/j.fertnstert.2014.04.042
更新日期:2014-08-01 00:00:00
abstract:OBJECTIVE:To assess whether a measure of uterine blood flow impedance (the pulsatility index, PI) as determined by transvaginal ultrasonography with color blood flow imaging, may be used to assess endometrial receptivity immediately before the time of embryo transfer (ET) after assisted conception. DESIGN:A prospectiv...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)54848-1
更新日期:1992-02-01 00:00:00
abstract::Adult beagle bitches received 0.2 to 75 mg/kg doses of medroxyprogesterone acetate (MPA) once every 3 months for 1 to 1.5 years. Doses greater than 2.0 mg/kg prevented the recurrence of ovarian cycles; lower doses did not. MPA (10 and 75 mg/kg) induced a dose-related development of multiple, large (greater than 5 mm d...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1981-09-01 00:00:00
abstract::Our studies demonstrate significantly lower expression of relaxin and its receptor in ectopic endometriotic tissues than their expression in eutopic endometrium and in endometrium from normal controls. These data suggest that in normal and eutopic endometrium, relaxin may exert a protective effect against endometriosi...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2010.06.051
更新日期:2010-12-01 00:00:00
abstract:OBJECTIVE:To quantify cytoplasmic maturity on the basis of intracytoplasmic sperm injection (ICSI) injection funnel manifestation and to evaluate influence factors of the latter. DESIGN:Prospective study. SETTING:Private fertility center. PATIENT(S):A total of 31 patients with good ovarian response. INTERVENTION(S)...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2016.06.015
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVE:To determine the effect of transdermal estrogen on insulin sensitivity in postmenopausal women and to compare this effect with changes observed with oral conjugated equine estrogens. DESIGN:Fourteen postmenopausal women were randomized to receive a transdermal E2 patch, 0.1 mg, for 25 days each month (n = 7)...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0015-0282(16)57181-7
更新日期:1994-12-01 00:00:00
abstract::We report an incidental finding of unrecognized lithopedion resulting from an old abdominal pregnancy with 35 years' evolution. Structures of the calcified fetus are seen clearly on abdominopelvic computed tomographic images. ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2009.12.019
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVE:To assess whether supplementation with hCG throughout the secretory phase of hormonally modulated cycles of frozen-thawed embryos might positively affect the outcome of such cycles. DESIGN:Prospective, randomized controlled trial. SETTING:University teaching hospital. PATIENT(S):Patients undergoing frozen-...
journal_title:Fertility and sterility
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.fertnstert.2009.02.027
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVE:To examine the literature systematically in order to identify prospective comparative trials answering the following question: Is vitrification of human embryos associated with a higher postthawing survival rate as compared with slow freezing? DESIGN:Systematic review and meta-analysis. SETTING:University-b...
journal_title:Fertility and sterility
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.fertnstert.2007.06.010
更新日期:2008-07-01 00:00:00
abstract:OBJECTIVE:To test the hypothesis that plasma visfatin concentrations will be higher in women with polycystic ovary syndrome (PCOS) than in women without PCOS. DESIGN:Clinical study. SETTING:University hospital. PATIENT(S):A total of 52 women were evaluated. Twenty-six had PCOS, and the remaining 26 were healthy wome...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2006.11.120
更新日期:2007-08-01 00:00:00
abstract::Surveillance is a triennial worldwide compendium of national rules and regulations for assisted reproductive technology. It was last published in 2010. ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2014.03.045
更新日期:2014-06-01 00:00:00
abstract:OBJECTIVE:To perform a highly detailed semen analysis in a man whose wife had a partial mole. DESIGN:Case report. SETTING:Gynecology departments of two university hospitals and a laboratory of histology/embryology. PATIENT(S):A 32-year-old man whose wife had a partial mole. INTERVENTION(S):Sperm characteristics wer...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2011.01.161
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVE:To evaluate the impact of female smoking on early embryo development in vitro using a time-lapse system. DESIGN:Retrospective analysis of prospectively collected database. SETTING:Assisted reproductive technology (ART) program. PATIENT(S):A total of 135 infertile couples undergoing IVF-intracytoplasmic spe...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2013.01.136
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVE:To report a child with Beckwith-Wiedemann syndrome (BWS) born after assisted reproductive technology (ART) to an HIV serodiscordant couple. DESIGN:Case report. SETTING:Academic medical center. PATIENT(S):A child with BWS born after ART to an HIV serodiscordant couple. INTERVENTION(S):Assisted reproductive...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2011.04.030
更新日期:2011-07-01 00:00:00
abstract::U. urealyticum with 15.8% and C. trachomatis antibodies with 15.4% were the most prevalent microbiological findings in 209 male infertility patients. The inflammatory marker granulocyte-elastase was significantly increased in men with C. trachomatis; these men also showed significantly decreased citric acid levels ind...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)54318-0
更新日期:1991-05-01 00:00:00
abstract:OBJECTIVES:To assess the occurrence of immunoglobulin (Ig) G, IgA, and IgA subclass antibodies against human sperm fertilization antigen-1 (FA-1) in cervical mucus (CM) and serum of women of infertile couples. DESIGN:Enzyme-linked immunosorbent assay methodology was used to detect anti-FA-1 antibodies. Antisperm antib...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)56217-7
更新日期:1993-10-01 00:00:00
abstract::Polycystic ovary disease generally is associated with elevated androgen levels and elevated luteinizing hormone (LH) levels, whereas follicle-stimulating hormone (FSH) levels are (sub)normal. To assess the role of androgens on gonadotropin secretion, we investigated the effect of 6 weeks of testosterone (T) undecanoat...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)54194-6
更新日期:1991-03-01 00:00:00
abstract:OBJECTIVE:To compare saline infusion sonography (SIS) with gel instillation sonography (GIS) in terms of feasibility and diagnostic accuracy. DESIGN:Prospective cohort study. SETTING:Leuven University bleeding clinic. PATIENT(S):A total of 804 patients: two consecutive cohorts of 402 women undergoing SIS or GIS. IN...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章
doi:10.1016/j.fertnstert.2010.04.074
更新日期:2011-01-01 00:00:00
abstract::Human testes, removed in treating patients for prostatic carcinoma, were used. Tissues were homogenized and incubated in vitro with labeled progesterone and 2 different antiovulatories, lynestrenol (17alpha-ethin yl-17beta-hydroxy-estr-4-one) and MK 665 (17alpha-chloroethinyl-19-nor-4 ,9(10)-androstadiene-17beta-ol-...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)36309-9
更新日期:1967-05-01 00:00:00
abstract:OBJECTIVE:To investigate the molecular mechanism for declining sperm motility in older men. DESIGN:Retrospective and prospective study. SETTING:University-based andrology unit. PATIENT(S):Semen was collected from 2,111 patients and sperm donors. INTERVENTION(S):None. MAIN OUTCOME MEASURE(S):Age, sperm concentratio...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2005.05.020
更新日期:2005-11-01 00:00:00