Magnetic resonance imaging and serum CA-125 in evaluating patients with endometriomas prior to medical therapy.

Abstract:

OBJECTIVE:To determine whether magnetic resonance imaging (MRI) and serum levels of CA-125 can be used to evaluate patients with endometriomas before initiating medical treatment. DESIGN:Comparative study before and after medical treatment. SETTING:Shimane Medical University Hospital, Izumo, Japan. PATIENTS:Eleven consecutive patients with at least one endometrioma > 10 mm in maximal diameter that was diagnosed by laparoscopy and treated with 900 micrograms/d buserelin acetate for 6 months. INTERVENTIONS:Magnetic resonance imaging and blood sampling was performed < 2 weeks before laparoscopy. MAIN OUTCOME MEASURES:Signal intensity of edometrioma/signal intensity of gluteus maximum muscle on T2-weighted image (T2SI:MSI); volume of endometrioma and serum CA-125. RESULTS:There was a positive linear correlation (r = 0.787) between T2SI:MSI before treatment and the extent of decrease in the volume of endometrioma. There was a negative linear relationship between serum CA-125 before treatment and the mean extent of decrease in the cyst volume (r = 0.678). The reduction in volume of endometrioma and T2SI:MSI before treatment related to the outcome of patients. CONCLUSION:The T2SI:MSI on MRI and serum CA-125 may be useful for estimating the outcome of patients with endometriomas before initiating medical treatment.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Takahashi K,Okada S,Okada M,Kitao M,Kaji Y,Sugimura K

doi

10.1016/s0015-0282(16)58087-x

subject

Has Abstract

pub_date

1996-02-01 00:00:00

pages

288-92

issue

2

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(16)58087-X

journal_volume

65

pub_type

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