Abstract：
OBJECTIVE:Oocyte donation (OD) from a family member may be more available to patients. Our objective was to compare reproductive outcomes of familial OD with those of unrelated OD. DESIGN:Retrospective cohort study in a single university-affiliated center. SETTING:Not applicable. PATIENT(S):Four hundred thirty OD cycles performed from 2010 to 2014: 124 from family members and 306 from unrelated donors. INTERVENTION(S):None. MAIN OUTCOME MEASURE(S):Ovarian stimulation parameters and cycle outcomes (total gonadotropin dose, number of retrieved oocytes, number of embryos, number of vitrified embryos, blastocyst transfer rate, rate of fresh transfers); endometrial preparation parameters; implantation, clinical pregnancy, miscarriage, and live birth rates; perinatal outcomes (gestational age at birth, birth weight, delivery mode, cesarean delivery rates). RESULT(S):Implantation, clinical pregnancy, miscarriage, and live birth rates were similar between familial OD cycles and unrelated OD cycles (32.9% vs. 39.7%, 41.9% vs. 44.4%, 30.7% vs. 30.9%, and 29% vs. 28.7%, respectively). Gestational age at birth and birth weight were similar (37.8 wk ± 2.2 d vs. 37.1 wk ± 3 d and 3,043 ± 722 g vs. 2,906 ± 788 g, respectively). Similar outcomes were also found in single-embryo transfer OD cycles (live birth rate 26.7% vs. 24.2%). Sister-to-sister OD cycles outcomes were similar to those of unrelated donors. CONCLUSION(S):The reproductive outcomes of familial OD are similar to those of unrelated OD. These findings are in contrast to previous presumptions regarding the efficiency of familial OD and may help in the counseling of women who need OD.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Hasson J,Tulandi T,Son WY,Al Ma'mari N,Badeghiesh A,Tannus S,Takefman J,Shavit Tdoi
10.1016/j.fertnstert.2016.08.042subject
Has Abstractpub_date
2016-12-01 00:00:00pages
1696-1702issue
7eissn
0015-0282issn
1556-5653pii
S0015-0282(16)62768-1journal_volume
106pub_type
杂志文章abstract：OBJECTIVE:To investigate the relation between the fetal environment and endometriosis. DESIGN:Prospective cohort study. SETTING:Nurses' Health Study II with 10 years of follow-up. PARTICIPANT(S):Eighty-four thousand, four hundred forty-six women aged 25-42 who had never been diagnosed with endometriosis, infertility...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2004.04.065
更新日期：2004-12-01 00:00:00
abstract：OBJECTIVE:To screen for cytomegalovirus (CMV) infection in male and female partners of subfertile couples and to analyze a potential relationship with clinically relevant parameters of male and female factor fertility. DESIGN:Prospective study. SETTING:Outpatient infertility clinic of a university-based hospital. PA...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2007.11.014
更新日期：2009-01-01 00:00:00
abstract：:Binovular follicles were found in 15 (0.3%) of 4,695 follicles containing oocytes. These binovular follicles were either with adjacent cumulus complexes (9 cases), or separate corona radiata and common cumulus mass (1 case), or two oocytes within a single zona pellucida (5 cases). In each of the latter form, there was...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)53948-x
更新日期：1990-11-01 00:00:00
abstract：:In this prospective, randomized clinical trial, we tested the hypothesis that a needle-free CO(2) injection system (Biojector 2000) would be better tolerated by patients when compared with traditional sharp needles used for gonadotropin injections during stimulation for IVF. As measured by our questionnaire, the needl...
journal_title：Fertility and sterility
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.fertnstert.2009.03.013
更新日期：2009-10-01 00:00:00
abstract：:The steroidogenic activity of purified theca interstitial cells (TIC) from polycystic ovaries of a patient with virilizing congenital adrenal hyperplasia due to 21-hydroxylase deficiency was studied in serum-free medium. The results show that CVAH TIC have high intrinsic basal androgen secretory activity that is drama...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)60450-8
更新日期：1989-01-01 00:00:00
abstract：:Intravaginal culture (IVC) is a new technique elaborated by the authors for the fertilization and culture of human oocytes. Its principle consists of fertilization and early development of the eggs in a closed, air-free milieu without the addition of CO2. One to five ovocytes are deposited in a tube completely filled ...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0015-0282(16)59835-5
更新日期：1988-04-01 00:00:00
abstract：OBJECTIVE:To determine the efficacy and safety of Repronex SC as compared with Repronex IM and Pergonal IM in patients undergoing IVF. DESIGN:Open-label, randomized, parallel-group, multicenter study. SETTING:Fifteen academic and private fertility clinics with IVF experience. PATIENT(S):Premenopausal women with regu...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/s0015-0282(00)00605-1
更新日期：2000-07-01 00:00:00
abstract：:Midluteal phase corpora lutea (CL) obtained from women induced with 50 mg (n = 5), 100 mg (n = 5), and 150 mg (n = 5) of clomiphene citrate (CC) were measured for luteinizing hormone/human chorionic gonadotropin (LH/hCG) concentrations and cytosol progesterone (P) and 17 alpha-hydroxyprogesterone (17-OHP) and compared...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1990-10-01 00:00:00
abstract：OBJECTIVE:Evaluate racial differences in reproducibility of hormone levels over time (estradiol, DHEAS, FSH, and testosterone) while adjusting for covariates previously identified as relevant in the study population. DESIGN:Longitudinal cohort study. SETTING:Healthy, late-reproductive-age women in a community-based s...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(00)01723-4
更新日期：2001-02-01 00:00:00
abstract：OBJECTIVE:To summarize current understanding of the effects of novel and prior coronaviruses on human reproduction, specifically male and female gametes, and in pregnancy. DESIGN:Review of English publications in PubMed and Embase to April 6, 2020. METHOD(S):Articles were screened for reports including coronavirus, r...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2020.04.025
更新日期：2020-06-01 00:00:00
abstract：OBJECTIVE:To assess the utility of endometrial thickness, echogenic endometrial pattern, and uterine artery impedance measured as pulsativity index in predicting implantation. DESIGN:Prospective case-controlled study of infertile patients undergoing assisted reproductive technologies (ARTs). PATIENTS:Four hundred fiv...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/s0015-0282(16)57065-4
更新日期：1994-11-01 00:00:00
abstract：:To show that in the dysgenetic gonads of 104 Turner syndrome patients no significant difference was found regarding the expression of the genes DAX1, FOG2, GATA4, OCT4, SF1, SRY, TSPY, WT1, and STRA8 compared with controls, except for genes OCT4, SRY, and TSPY in both gonads of a patient whose chromosomal constitution...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2010.02.036
更新日期：2010-11-01 00:00:00
abstract：OBJECTIVE:To determine the feasibility of asking women undergoing fertility treatment the maximum increased risk of ovarian cancer they would be willing to tolerate in order to take ovulation-induction drugs. DESIGN:A prospective pilot study of women attending fertility clinics over a 2-month period. SETTING:Two tert...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(97)81481-1
更新日期：1997-07-01 00:00:00
abstract：:The interaction of medroxyprogesterone acetate (MPA) with cortisol binding to corticosteroid-binding globulin (CBG) was studied with the use of an aqueous two-phase system with polyethylene glycol and dextran for equilibrium partition. Competitive binding analyses were also performed for progesterone (P), levonorgestr...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)48612-7
更新日期：1985-06-01 00:00:00
abstract：:The force generated by the radiation pressure of a low power laser beam induces an optical trap which may be used to manipulate sperm. We studied the effect of the optical trap on sperm motility. A Nd:YAG laser beam was coupled to a conventional microscope and focused into the viewing plane by the objective lens. Sper...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1989-11-01 00:00:00
abstract：OBJECTIVES:To evaluate sequential changes in fetal heart rate (FHR) during the first trimester of well-timed pregnancies resulting from infertility treatment and to correlate the data with fetal growth curve and beta-hCG levels. DESIGN:Serial measurements of FHR, crown-rump length (CRL) and beta-hCG at weekly interval...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)55971-8
更新日期：1993-06-01 00:00:00
abstract：OBJECTIVE:To examine total ezrin expression (ezrin and phospho-ezrin) through the normal endometrial cycle and to correlate ezrin activation and localization with cytologic changes. DESIGN:Experimental laboratory study. SETTING:University medical centers. PATIENT(S):Reproductive-age women. INTERVENTION(S):A total o...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2011.10.039
更新日期：2012-01-01 00:00:00
abstract：:The tenet that a combination of human follicle-stimulating hormone (hFSH)/human menopausal gonadotropin (hMG) improves follicular recruitment was assessed by randomly treating ovulatory women either with hFSH/hMG on days 3 and 4 of the cycle followed by two ampules of hMG daily or with a constant daily dose of 2 ampul...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0015-0282(16)60315-1
更新日期：1988-11-01 00:00:00
abstract：OBJECTIVE:To analyze the role of the local renin-angiotensin system (RAS) in the female reproductive system to modulate ovarian steroidogenesis and its relationship with alpha(1)adrenergic receptors. DESIGN:Observational study. SETTING:University laboratory. ANIMAL(S):Adult female Wistar rats treated with doxazosin ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2006.12.021
更新日期：2007-10-01 00:00:00
abstract：OBJECTIVE:To see if clinicians' impressions were influenced by expert opinion on patient selection criteria that influence magnetic resonance-guided focused ultrasound (MRgFUS) leiomyoma treatment. DESIGN:Survey-based study. SETTING:First international symposium devoted to MRgFUS, "MRgFUS 2008," October 6-7, 2008, Wa...
journal_title：Fertility and sterility
pub_type：
doi：10.1016/j.fertnstert.2009.02.083
更新日期：2010-06-01 00:00:00
abstract：OBJECTIVE:To compare the effects of intrauterine and subdermal administration of levonorgestrel on control of bleeding and on the endometrium in postmenopausal hormone replacement therapy. INTERVENTIONS:Nineteen women started continuous oral E2 valerate therapy (2 mg daily) together with continuous parenteral progesti...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0015-0282(16)57365-8
更新日期：1995-02-01 00:00:00
abstract：OBJECTIVE:To present and determine the impact of the Mindfulness-Based Program for Infertility (MBPI). DESIGN:Controlled clinical trial. SETTING:University research unit. PATIENT(S):Fifty-five infertile women completed the MBPI, and 37 infertile women were assigned to a control group. INTERVENTION(S):The MBPI inclu...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2013.05.036
更新日期：2013-10-01 00:00:00
abstract：:Collagenolytic enzyme activities presumed to play an important role in ovulation were investigated in the human follicular apex, base, and granulosa cell layer throughout the ovarian cycle. Those analyzed were human ovarian collagenase, 2,4-dinitrophenyl-Pro-Gln-Gly-Ile-Ala-Gly-Gln-D-Arg-OH peptidase, N-carbobenzoxy-G...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)45920-0
更新日期：1981-12-01 00:00:00
abstract：OBJECTIVE:To describe a woman with a nonmosaic (45,X) form of Turner's syndrome who gave birth to a girl with 45,X Turner syndrome. DESIGN:Patient report. SETTING:Outpatient clinic of a university hospital. PATIENT(S):A woman with typical phenotypic features of Turner syndrome and a 45,X karyotype and her daughter w...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2004.02.129
更新日期：2004-10-01 00:00:00
abstract：:Our studies demonstrate significantly lower expression of relaxin and its receptor in ectopic endometriotic tissues than their expression in eutopic endometrium and in endometrium from normal controls. These data suggest that in normal and eutopic endometrium, relaxin may exert a protective effect against endometriosi...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2010.06.051
更新日期：2010-12-01 00:00:00
abstract：OBJECTIVE:To evaluate endocrine characteristics and clinical outcomes in normal ovulatory patients undergoing controlled ovarian hyperstimulation (COH) with the use of a Duphaston and hMG protocol during in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) treatments in combination with frozen-thawed em...
journal_title：Fertility and sterility
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.fertnstert.2017.06.017
更新日期：2017-09-01 00:00:00
abstract：OBJECTIVE:To identify if there are certain cutoff levels for P and or the P/E(2) ratio on the day of hCG that would be defined as detrimental for occurrence of pregnancy in women with normal ovarian reserve undergoing cleavage-stage embryo transfer (ET). Secondarily, to determine if these same cutoffs might have the sa...
journal_title：Fertility and sterility
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.fertnstert.2010.12.065
更新日期：2011-04-01 00:00:00
abstract：OBJECTIVE:To explore the long-term outcome of patients who began IVF treatment by considering not only treatment outcome in the center but also the parenthood project outcome after discontinuation of unsuccessful IVF. DESIGN:Retrospective cohort follow-up study. SETTING:Two French IVF centers. PATIENT(S):Seven hundr...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.05.067
更新日期：2009-07-01 00:00:00
abstract：OBJECTIVE:To analyze information on assisted reproductive technology (ART) performed worldwide and trends in outcomes over successive years. DESIGN:Cross-sectional survey on access, effectiveness, and safety of ART procedures performed in 53 countries during 2005. SETTING:A total of 2,973 clinics from national and re...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2013.10.005
更新日期：2014-02-01 00:00:00
abstract：:Twelve women of normal weight (ages 17 to 36 years) with scanty menstrual bleeding were studied. They had no signs of virilization, gynecologic or endocrine pathology, or past history of hormonal treatment. Five women (group 1) experienced withdrawal bleeding after a 3-day course of chlormadinone acetate (2 mg/day) an...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)43213-9
更新日期：1978-04-01 00:00:00
