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The prostaglandin inhibitor effect of antiinflammatory drugs in the therapy of male infertility.

Abstract：

:The effects of various doses of indomethacin and ketoprofen as compared with placebo were examined in 100 oligospermic patients who participated in this study. It was found that the treatment increased sperm count, sperm motility, and fertilizing capacity. The radioimmunoassay examination showed an increase in plasma follicle-stimulating hormone and luteinizing hormone but a decrease in testosterone. The results show that the influence of indomethacin was better in the dose of 75 mg daily. The mechanism of those changes is not clear. Treatment should be at least 60 days.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Barkay J,Harpaz-Kerpel S,Ben-Ezra S,Gordon S,Zuckerman H

doi

10.1016/s0015-0282(16)48081-7

subject

Has Abstract

pub_date

1984-09-01 00:00:00

pages

406-11

issue

3

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(16)48081-7

journal_volume

42

pub_type

临床试验,杂志文章

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