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Expression of aromatase (P450 aromatase/CYP19) in peritoneal and ovarian endometriotic tissues and deep endometriotic (adenomyotic) nodules of the rectovaginal septum.

Abstract：

:We found, by reverse transcription--real time--polymerase chain reaction, that the expression of aromatase (CYP19) in ovarian, peritoneal endometriosis, and deep endometriotic nodules is significantly different, which strengthens the theory of three distinct clinical entities. Compared with peritoneal endometriosis, ovarian endometriosis exhibits an 8-fold higher expression of aromatase, which suggests that aromatase inhibitors may be particularly active in this form of endometriosis.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Heilier JF,Donnez O,Van Kerckhove V,Lison D,Donnez J

doi

10.1016/j.fertnstert.2005.10.041

keywords:

subject

Has Abstract

pub_date

2006-05-01 00:00:00

pages

1516-8

issue

5

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(06)00083-5

journal_volume

85

pub_type

临床试验,杂志文章

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