Abstract:
OBJECTIVE:To achieve fertilization and cleavage by spermatids without tails from testicular biopsy. DESIGN:Clinical trial. SETTING:Reproductive unit of a university teaching hospital. PATIENT:A patient of obstructive azoospermia with defective spermiogenesis. INTERVENTION:Testicular biopsy after scrotal exploration and spermatid injection into the cytoplasm of oocyte. MAIN OUTCOME MEASURES:Fertilization and cleavage. RESULTS:Four of 13 spermatid injections achieved normal fertilization and 2 of them cleaved. CONCLUSION:Intracytoplasmic spermatid injection may be a possible treatment for patients of defective spermiogenesis who have no viable spermatozoa available.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Chen SU,Ho HN,Chen HF,Tsai TC,Lee TY,Yang YSdoi
10.1016/s0015-0282(16)58406-4subject
Has Abstractpub_date
1996-07-01 00:00:00pages
157-60issue
1eissn
0015-0282issn
1556-5653pii
S0015-0282(16)58406-4journal_volume
66pub_type
临床试验,杂志文章abstract:OBJECTIVE:To determine if androstenedione (A) and progesterone (P) concentrations in preovulatory follicular fluid (FF) correlate with successful fertilization and cleavage of human oocytes in vitro. DESIGN:A retrospective randomized trial. SETTING:Hospital department of obstetrics and gynecology. PATIENTS:Fifty-fiv...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0015-0282(16)54489-6
更新日期:1991-08-01 00:00:00
abstract:OBJECTIVE:To evaluate semen characteristics, testicular volume, and hormonal levels of normal fertile men requiring vasectomy for sterilization. DESIGN:Retrospective study. SETTING(S):Academic medical centers. PATIENT(S):A total of 889 patients underwent a vasectomy for sterilization. INTERVENTION(S):None. MAIN OU...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2005.09.032
更新日期:2006-04-01 00:00:00
abstract::The effect of six metabolically active compounds, namely caffeine, kallikrein, cyclic adenosine 3':5'-monophosphate, prostaglandin E, triiodothyronine, and insulin on spermatozoal motility was investigated. Hypokinetic and normokinetic semen specimens from fertile and infertile patients were incubated with various con...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1980-06-01 00:00:00
abstract:OBJECTIVE:To assess the effectiveness of luteal start vaginal micronized P in a recurrent pregnancy loss (RPL) cohort. DESIGN:Observational cohort study using prospectively collected data. SETTING:Not applicable. PATIENT(S):Women seen between 2004 and 2012 with a history of two or more unexplained pregnancy losses <...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2016.11.029
更新日期:2017-03-01 00:00:00
abstract:OBJECTIVE:Immunobead testing (IBT), the current standard for antisperm antibody detection, is time consuming and somewhat subjective. To overcome these limitations and maintain accuracy, we studied an immunofluorescent assay using flow cytometry. DESIGN:A validation study comparing flow cytometry to IBT in the detecti...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1995-04-01 00:00:00
abstract:OBJECTIVE:To present a case report of a spontaneous, heterotopic, triplet conception of a patient without any risk factors. DESIGN:Case report. SETTING:Community hospital in Park Ridge, Illinois. PATIENT(S):One patient, 30-year-old multigravida, sent to the emergency room for evaluation of right lower quadrant pain ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2006.12.034
更新日期:2007-10-01 00:00:00
abstract:OBJECTIVE:To assess long-term fracture risk after hysterectomy, with or without oophorectomy. DESIGN:Population-based, cohort study. SETTING:Olmsted County, Minnesota. PATIENT(S):Women residing in Olmsted County (n = 9,258) who underwent hysterectomy in 1965-2002, compared to an equal number of age- and sex-matched ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2006.11.080
更新日期:2007-07-01 00:00:00
abstract:OBJECTIVE:To determine the possible effect of freezing on sperm escape force as measured by laser trap. DESIGN:Controlled clinical study. SETTING:Normal volunteers, academic setting. PATIENTS:Normal, healthy volunteers. INTERVENTION:Sperm selection, freezing and thawing. Measurement of relative (sperm) escape force...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVE:To determine whether the use of GnRH antagonist in cycles converted from ovulation induction-IUI to IVF affects cycle outcome and pregnancy rates. DESIGN:Retrospective cohort study. SETTING:Academic research institution. PATIENT(S):One hundred eighty-two consecutive patients with ovulation induction-IUI to...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2009.01.109
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVE:To improve the sperm chromatin dispersion (SCD) test and develop it as a simple kit (Halosperm kit) for the accurate determination of sperm DNA fragmentation using conventional bright-field microscopy. DESIGN:Method development, comparison, and validation. SETTING:Medical genetics laboratory, academic biolo...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2004.11.089
更新日期:2005-10-01 00:00:00
abstract::The antiprogesterone compound RU 486 (17 beta-hydroxy-11 beta-[4-dimethylaminophenyl]-17 alpha-[ 1-propynyl]estra-4,9-dien-3-one; Roussel-Uclaf, Paris, France) was used to induce menstruation in a randomized controlled trial. Castrated adult female cynomolgus monkeys (n = 17) received sequential subcutaneous Silastic ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)47246-8
更新日期:1983-08-01 00:00:00
abstract::Selenium (Se) was measured in the semen of 125 men from couples consulting for infertility. A mean concentration of 71.3 +/- 29.7 ng/ml of semen was found, with a range of 7 to 230 ng/ml. More than 85% of the Se is in the seminal plasma. There was a significant positive correlation between sperm count and semen Se. Sp...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1984-12-01 00:00:00
abstract:OBJECTIVE:To investigate the relationship between growth hormone (GH) and luteal function. DESIGN:In vivo comparative and in vitro culture studies. SETTING:University hospital. PATIENT(S):Eighteen women who were interested in becoming pregnant and visited our clinic voluntarily participated in the study for urinary ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2007.07.1304
更新日期:2008-09-01 00:00:00
abstract::This document is designed to assist in vitro fertility clinics in the management of cryopreserved reproductive tissues stored in cryogenic storage (cryostorage) tanks, based upon scientific principles and laboratory experience related to best practice for safe and reliable storage of cryopreserved reproductive tissue....
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2020.06.019
更新日期:2020-09-01 00:00:00
abstract::Nitrofurantoin sodium and nitorfurazone, in certain critical concentrations, have the ability to immobilize spermatozoa. In this study, this effect was consisitent with both 5:1, and 10:1 dilutions. Histologic examination of the effects of these drugs as intraoperative vas irrigants revealed no apparent tissue toxicit...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)41168-4
更新日期:1975-06-01 00:00:00
abstract::Specimens for chlamydial culture, direct fluorescent antibody (DFA) test, two enzyme immunoassays (EIA) for antigen detection, and serum for chlamydial antibodies were collected from 256 infertile women. Specimens were taken from the tubes during tuboplasty and from the cervix and endometrium during laparoscopy or tub...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1991-02-01 00:00:00
abstract:OBJECTIVE:To explore the relationship between men's age and DNA damage repair proteins related to apoptosis in human testicular germ cells. DESIGN:Retrospective case-control study. SETTING:Academic institutions. PATIENT(S):Testicular specimens were obtained from 22 fertile volunteers aged 20-82 years. INTERVENTION(...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.03.027
更新日期:2009-05-01 00:00:00
abstract::Two hundred ten treatment cycles of follicle-stimulating hormone (FSH) or human menopausal gonadotropin (hMG) were completed in 49 patients with clomiphene citrate-resistant polycystic ovarian syndrome. The results from 68 cycles of daily intramuscular (IM) FSH and 41 cycles of IM hMG were compared. The ovulation rate...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)53511-0
更新日期:1990-05-01 00:00:00
abstract::We found, by reverse transcription--real time--polymerase chain reaction, that the expression of aromatase (CYP19) in ovarian, peritoneal endometriosis, and deep endometriotic nodules is significantly different, which strengthens the theory of three distinct clinical entities. Compared with peritoneal endometriosis, o...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章
doi:10.1016/j.fertnstert.2005.10.041
更新日期:2006-05-01 00:00:00
abstract::In this study, acrosin activity and hyaluronic acid binding were compared in sperm from men with spinal cord injury versus sperm from healthy controls. The results showed statistically significantly lower acrosin activity and statistically significantly lower hyaluronic acid binding in spinal cord injured patients com...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2010.01.015
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE:To investigate c-fos and matrix metalloproteinase-9 (MMP-9) expression in the endometrium from women with or without endometriosis throughout the menstrual cycle, and to explore the correlation of c-fos expression with MMP-9 expression and 17beta-E(2) levels in serum. DESIGN:Molecular studies in human tissue...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2007.07.1386
更新日期:2008-10-01 00:00:00
abstract::Two-cell mouse embryos were cultured in Ham's F-10 medium (Gibco, Grand Island, NY) supplemented with various concentrations of transferrin, insulin, epidermal growth factor, platelet-derived growth factor, or fibroblast growth factor. Rates of development and the cell numbers per blastocyst were compared between embr...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)54082-5
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:To analyze the endometrium sonographically in patients undergoing controlled ovarian stimulation with clomiphene citrate (CC) in addition to menotropins to determine the significance of endometrial pattern and thickness on pregnancy rate (PR). DESIGN:A prospective study analyzing patients receiving sequentia...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(97)81509-9
更新日期:1997-08-01 00:00:00
abstract:OBJECTIVE:To conduct a pilot study to investigate the possible presence of bacteria throughout the female reproductive tract and to make a preliminary assessment of whether there are differences in the composition of the microbial communities between these body sites and/or between patients. DESIGN:Prospective pilot s...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2016.11.028
更新日期:2017-03-01 00:00:00
abstract:OBJECTIVE:To identify biomarkers associated with reproductive outcome using proton nuclear magnetic resonance ((1)H NMR) metabolomic profiling of embryo culture media. DESIGN:Retrospective study. SETTING:An academic assisted reproductive technology (ART) program; a university research center. PATIENT(S):Women underg...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.07.1739
更新日期:2008-12-01 00:00:00
abstract:OBJECTIVE:To identify the risk factors for ectopic pregnancy (EP) in women using an intrauterine device (IUD). DESIGN:Case-control study. SETTING:Auvergne region (France). PATIENT(S):Women using an IUD and suffering EP (243 cases) or having an intrauterine pregnancy (140 controls). INTERVENTION(S):None. MAIN OUTCO...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(00)01605-8
更新日期:2000-11-01 00:00:00
abstract:OBJECTIVE:To study the value of virtual hysterosalpingography (VHSG) in the diagnosis of bicornuate vs. septate uterus. DESIGN:Retrospective study of all cases with bicornuate or septate uterus that had VHSG during the last 3 years at our center. SETTING:Private fertility center and radiology institute with universit...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2011.08.026
更新日期:2011-11-01 00:00:00
abstract::We present a case of combined intrauterine and cornual (interstitial) pregnancy after IVF-ET, with survival of the infant after the cornual pregnancy. The diagnosis of this rare phenomenon is difficult; a high index of suspicion and frequently ultrasound monitoring may enable early diagnosis in other forms of heteroto...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)53473-6
更新日期:1990-04-01 00:00:00
abstract:OBJECTIVE:To describe an ovarian abscess presenting very late after oocyte retrieval for IVF with several unusual clinical features. DESIGN:Case report. SETTING:Academic medical center. PATIENT(S):A 35-year-old nulliparous woman underwent IVF with uncomplicated transvaginal oocyte retrieval (TVOR), resulting in a di...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2005.12.045
更新日期:2006-07-01 00:00:00
abstract:OBJECTIVE:To review the literature to determine the magnitude of the effect of 150 micrograms desogestrel-30 micrograms ethinyl E2, an oral contraceptive (OC) formulation, on plasma lipid concentrations in healthy women using meta-analysis techniques. DATA SOURCES:All English-language published reports (1981 to 1991) ...
journal_title:Fertility and sterility
pub_type: 杂志文章,meta分析
doi:
更新日期:1996-06-01 00:00:00