Abstract:
:Preimplantation genetic diagnosis has been proposed as a method to improve assisted reproduction technology outcomes, but different techniques have produced conflicting results. The use of appropriate techniques may provide positive outcomes.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Munné S,Wells D,Cohen Jdoi
10.1016/j.fertnstert.2009.02.091subject
Has Abstractpub_date
2010-07-01 00:00:00pages
408-30issue
2eissn
0015-0282issn
1556-5653pii
S0015-0282(09)00520-2journal_volume
94pub_type
杂志文章,评审abstract:OBJECTIVE:To explore the contribution of an altered structure of sperm mitochondria to human asthenozoospermia. DESIGN:A retrospective study. SETTING:Andrology Clinic, University of L'Aquila. PATIENT(S):Fifteen ejaculates with forward motility (FM) ≥ 50%, and 57 asthenozoospermic ejaculates (FM <50%, sperm vitality ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2010.07.1086
更新日期:2011-02-01 00:00:00
abstract:OBJECTIVE:To enable serodiscordant couples to reproduce while minimizing the risk of infecting the female partner and to demonstrate the feasibility of including these couples in an insemination program. DESIGN:Prospective follow-up study. SETTING:Ambulatory IUIs. PATIENT(S):Fifty-six HIV-1-serodiscordant couples wi...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章
doi:10.1016/j.fertnstert.2004.02.128
更新日期:2004-10-01 00:00:00
abstract:OBJECTIVE:To evaluate the association of oocyte donor-recipient characteristics, oocyte donor response, and live birth pregnancy rate following fresh donor oocyte IVF-ET. DESIGN:Retrospective cohort study. SETTING:Academic reproductive medicine practice. PATIENT(S):Two hundred thirty-seven consecutive fresh donor oo...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2017.05.021
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficiency of using a continuous (one-step) protocol with a single medium for the culture of human embryos in a time-lapse incubator (TLI). DESIGN:Prospective cohort study on sibling donor oocytes. SETTING:University-affiliated in vitro fertilization (IVF) center. PATIENT(S):Embryos from 59...
journal_title:Fertility and sterility
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.fertnstert.2015.11.038
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVE:To report a case of a methotrexate (MTX)-resistant heterotopic interstitial pregnancy in which dactinomycin was necessary as a second-line chemotherapy. DESIGN:Case report. SETTING:Medical college-affiliated hospital. PATIENT(S):A 39-year-old woman with vaginal bleeding after the transfer of two thawed 8-c...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.10.003
更新日期:2009-03-01 00:00:00
abstract:OBJECTIVE:To determine whether antisperm autoantibody production after prepubertal vas injury is influenced by immediate repair of the vas compared to delay of the reanastomosis until sexual maturity. DESIGN:Animal study comparing early repair, late repair, and sham-operated groups. SETTING:Research laboratory in a m...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(99)00501-4
更新日期:2000-02-01 00:00:00
abstract:OBJECTIVE:To improve the maturation rate of murine and human germinal vesicle (GV) oocytes using human tubal epithelial cells (hTECs). DESIGN:Murine and human GV oocytes were randomized to human tubal fluid (HTF) media alone or cocultured with mouse embryonic fibroblasts (MEFs) or primary hTECs or immortalized hTECS (...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2010.08.034
更新日期:2011-03-15 00:00:00
abstract:OBJECTIVE:To verify the percentage of chromosomally abnormal preimplantation embryos in patients with a poor prognosis and possibly to increase the chance of implantation by selecting chromosomally normal embryos. DESIGN:A prospective, randomized, controlled study. SETTING:In vitro fertilization program at the Reprod...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0015-0282(97)00412-3
更新日期:1997-12-01 00:00:00
abstract:OBJECTIVE:To evaluate the transcription and translation ability of mitochondria in terminally differentiated granulosa cells, these cells were incubated with ionic calcium. DESIGN:Prospective laboratory research. SETTING:In vitro fertilization laboratory in a university hospital. PATIENT(S):Granulosa cells were harv...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2005.03.072
更新日期:2005-10-01 00:00:00
abstract:OBJECTIVE:To use DNA microarrays to identify differentially expressed genes in eutopic endometrium compared with ectopic endometrium. DESIGN:Prospective, cross-sectional, observational study. SETTING:University Medical Center and Research Laboratory. PATIENT(S):Eleven women with endometriosis. INTERVENTION(S):None....
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2007.01.056
更新日期:2007-12-01 00:00:00
abstract::The assessment of anti-phospholipid antibodies (APA) is not indicated among couples undergoing IVF, and therapy is not justified on the basis of existing data. ...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/j.fertnstert.2008.08.100
更新日期:2008-11-01 00:00:00
abstract::The effectiveness of antiestrogens and progestins in the inhibition of capacitation in the rabbit uterus and oviduct was studied. The agents tested were 8 mg/day nafoxidine HCL (NHCL), 4 mg/day fluoxymesterone (FM), 4 and 20 mg/day clomiphene citrate (CC), 8 mg/day testosterone (T), 8 mg/day dydrogesterone (D) 4 and ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1972-03-01 00:00:00
abstract::The effects of various concentrations of rosiglitazone on in vitro rat embryo growth and morphology during the critical period of organogenesis was evaluated. We found that rosiglitazone has no significant effects on growth and morphology of in vitro early embryo development, even at very high concentrations. ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2005.12.069
更新日期:2006-08-01 00:00:00
abstract:OBJECTIVE:To further understand the association between semen quality and cancer risk by means of well defined semen parameters. DESIGN:Retrospective cohort study. SETTING:Not applicable. PATIENT(S):A total of 20,433 men who underwent semen analysis (SA) and a sample of 20,433 fertile control subjects matched by age...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2015.10.027
更新日期:2016-02-01 00:00:00
abstract::The Ethics Committee recommends development of evidence-based policies that are patient centered for each IVF center. In most cases, the provision of futile therapies is not ethically justifiable. For those treatments with very poor success rates, clinicians must be vigilant in their presentation of risks, benefits, a...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/j.fertnstert.2009.07.979
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVE:To systematically review the literature to identify the impact of polycystic ovary syndrome (PCOS) on specific health-related quality of life domains. DESIGN:Meta-analysis. SETTING:N/A. PATIENT(S):The outcomes of 423 patients and 285 controls from 5 articles that used the Short Form 36 (SF-36) questionnair...
journal_title:Fertility and sterility
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.fertnstert.2011.05.072
更新日期:2011-08-01 00:00:00
abstract:OBJECTIVE:To determine if sperm exposure to P produces an enhancement in its fertilizing capacity. DESIGN:Sperm from fertile donors were exposed to P at 0.1 and 1.0 microgram/mL for 1 or 24 hours. The effects on hyperactivated (HA) motility at 1 and 4 hours, acrosome reaction (as determined by Pisum sativum agglutinin...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)56051-8
更新日期:1993-07-01 00:00:00
abstract:OBJECTIVE:To evaluate the association between FSH efficacy and FSHR alleles. DESIGN:Retrospective study. SETTING:University-based fertility unit and a private center for biomedical research. PATIENT(S):One hundred two women with ovarian function who were undergoing controlled ovarian stimulation (COS). Women were ca...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(03)00795-7
更新日期:2003-09-01 00:00:00
abstract:OBJECTIVE:Compliance with recent recommendations concerning hormone therapy (HT) requires that we understand the reasons why women receiving HT continue or stop their treatment. Our aim was to estimate the duration of HT use and analyze factors associated with its discontinuation during the period before the publicatio...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2004.12.040
更新日期:2005-06-01 00:00:00
abstract:OBJECTIVE:To assess insulin and insulin-like growth factor I (IGF-I) action in women with polycystic ovarian syndrome (PCOS). DESIGN:Hyperinsulinemia was determined by measuring the insulin responses during a 2-hour oral glucose tolerance test (OGTT). Quantification of in vivo insulin action was determined by a freque...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1992-04-01 00:00:00
abstract::After initial videolaseroscopy for the treatment of endometriosis-associated infertility, 157 patients underwent a second-look laparoscopy to evaluate and treat recurrence of disease and/or adhesions. The patients were divided into two groups. Group 1 consisted of 135 patients who underwent second-look laparoscopy for...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)53576-6
更新日期:1990-06-01 00:00:00
abstract:OBJECTIVE:To determine the prevalence of anticardiolipin and antiphophatidylserine antibodies in an IVF population and to correlate their presence and specific isotype with IVF cycle outcome. DESIGN:Retrospective clinical study using stored midfollicular sera for determination of antibody status. SETTING:University h...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(97)81519-1
更新日期:1997-08-01 00:00:00
abstract:OBJECTIVE:To characterize the molecular mechanisms by which estrogens reduce adipose tissue mass, with particular focus on genes involved in lipogenesis. DESIGN:This study involves one arm of an open randomized clinical study with parallel group comparison. SETTING:Women's health clinical research unit at a universit...
journal_title:Fertility and sterility
pub_type: 杂志文章,多中心研究
doi:10.1016/j.fertnstert.2007.06.011
更新日期:2008-07-01 00:00:00
abstract:OBJECTIVE:To compare pregnancy rates after fallopian tubal and uterine transfer of cryopreserved embryos. DESIGN:Prospective randomized trial with assignment to treatment groups by a random number table. SETTING:University of Iowa Hospitals and Clinics, a tertiary care academic institution. PATIENTS:Forty patients w...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0015-0282(16)57429-9
更新日期:1995-03-01 00:00:00
abstract::We prospectively evaluated the behavior of serum 17-hydroxyprogesterone (17-OHP), sex-steroid hormones, and C-reactive protein (CRP) levels in 27 patients during controlled ovarian hyperstimulation (COH) for in vitro fertilization (IVF). While routine measurement of COH via serum 17-OHP may replace estradiol (E(2)) an...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2007.05.024
更新日期:2008-05-01 00:00:00
abstract:OBJECTIVE:To assess whether supplementation with hCG throughout the secretory phase of hormonally modulated cycles of frozen-thawed embryos might positively affect the outcome of such cycles. DESIGN:Prospective, randomized controlled trial. SETTING:University teaching hospital. PATIENT(S):Patients undergoing frozen-...
journal_title:Fertility and sterility
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.fertnstert.2009.02.027
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVE:To examine differences in specific protein expression from the surface of the human endometrium with respect to eventual pregnancy in infertile women. DESIGN:Laboratory study. SETTING:University hospital. PATIENT(S):Thirty-one women presenting for investigation into infertility at an assisted reproductive ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2007.01.094
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVE:To study the association between low percentages of intact sperm acrosomes and fertilization failures in conventional IVF procedures. DESIGN:A retrospective study. SETTING:Clinical and academic research environment. PATIENT(S):Patients undergoing treatment of infertility. INTERVENTION(S):Sperm cells were ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(99)00201-0
更新日期:1999-07-01 00:00:00
abstract:OBJECTIVE:To assess the clinical value of bisulfite polymerase chain reaction Luminex (BPL), an automated, high-throughput procedure for the detection of alterations in DNA methylation. DESIGN:Experimental prospective study. SETTING:University research laboratory and private in vitro fertilization (IVF) clinic. PATI...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章
doi:10.1016/j.fertnstert.2010.06.076
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVE:To assess the variability of antimüllerian hormone (AMH) concentrations in women with "adequate ovarian reserve" during unstimulated menstrual cycles and to determine the impact on clinical classifications. DESIGN:Pilot cohort study. SETTING:Private fertility clinic. PATIENT(S):Twelve consecutive women (ag...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2013.01.132
更新日期:2013-05-01 00:00:00