Abstract:
OBJECTIVE:To compare fecundity rates following intrauterine insemination (IUI) with donor sperm frozen conventionally versus an IUI-ready preparation. DESIGN:Both retrospective results and a prospective, randomized study where recipients were assigned to one of two sperm cryopreservation methods in each cycle of intrauterine insemination are reported. SETTING:University-based infertility practice, affiliated private practices, and andrology laboratory. PATIENT(S):Women desiring therapeutic insemination in an effort to establish pregnancy. INTERVENTION(S):Intrauterine insemination with donor sperm frozen conventionally or by an IUI-ready protocol. MAIN OUTCOME MEASURE(S):Cycle fecundity in donor IUI recipients. RESULT(S):In a retrospective analysis involving 642 inseminations in 209 recipients, 79 pregnancies were recorded for an overall pregnancy rate of 12.3% per insemination (or cycle): 11.3% with IUI-ready sperm and 13.9% with conventionally preserved sperm. In a follow-up prospective, randomized study, the pregnancy rate for IUI-ready sperm preparations was 36% per cycle (14 of 39) whereas that for conventionally preserved sperm was 19.6% per cycle (9 of 46). Thirteen of the 23 pregnancies occurred in the first study cycle of insemination; only two pregnancies were observed in patients undergoing more than four cycles of insemination. CONCLUSION(S):Cycle fecundity for IUI-ready donor sperm is equivalent to conventional cryopreserved sperm based on both prospective and retrospective assessments.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Wolf DP,Patton PE,Burry KA,Kaplan PFdoi
10.1016/s0015-0282(01)01857-xkeywords:
subject
Has Abstractpub_date
2001-07-01 00:00:00pages
181-5issue
1eissn
0015-0282issn
1556-5653pii
S0015-0282(01)01857-Xjournal_volume
76pub_type
临床试验,杂志文章,随机对照试验abstract:OBJECTIVE:To provide an up-to-date comprehensive review of published data on laparoscopic methods of ovulation induction in the polycystic ovary syndrome (PCOS). Areas to be considered include the historical background of these procedures, their outcomes as reported in the literature, and their potential adverse effect...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/s0015-0282(16)57408-1
更新日期:1995-03-01 00:00:00
abstract:OBJECTIVE:To analyze rates of chromosomal anomalies in a patient with globozoospermia. DESIGN:Case report. SETTING:Tertiary-care infertility clinic. PATIENT(S):A 44-year-old man with 100% globozoospermia. INTERVENTION(S):Fixation of sperms and analysis of aneuploidies and diploidies by fluorescence in situ hybridiz...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2005.01.109
更新日期:2005-07-01 00:00:00
abstract:OBJECTIVE:To determine if androstenedione (A) and progesterone (P) concentrations in preovulatory follicular fluid (FF) correlate with successful fertilization and cleavage of human oocytes in vitro. DESIGN:A retrospective randomized trial. SETTING:Hospital department of obstetrics and gynecology. PATIENTS:Fifty-fiv...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0015-0282(16)54489-6
更新日期:1991-08-01 00:00:00
abstract:OBJECTIVE:To identify factors associated with cancer treatment-induced amenorrhea and time to return of menses. DESIGN:Population-based cohort study. SETTING:Not applicable. PATIENT(S):Female cancer survivors who were diagnosed with cancer between the ages of 20 and 35 and were at least 2 years postdiagnosis at the ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2015.11.020
更新日期:2016-03-01 00:00:00
abstract::When dispersed spermatogenic cells obtained by enzymatic digestion from prepuberal mice, adult male mice, nonazoospermic men and normospermic men were observed live using Normarski optics, it was found that, respectively, 47.4%, 1.4%, 5.1%, and 2.4% of them protruded active pseudopodia. These cells were 8 to 10 mum in...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2007.06.055
更新日期:2008-08-01 00:00:00
abstract:OBJECTIVE:To report the case of a patient submitted to laparoscopic bowel resection in whom histology revealed endometriosis and schistosomiasis. DESIGN:Case report. SETTING:Multidisciplinary group practice and teaching hospital. PATIENT(S):A 31-year-old patient with pelvic pain. INTERVENTION(S):Laparoscopic bowel ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2005.08.068
更新日期:2006-04-01 00:00:00
abstract:OBJECTIVE:To reduce estrogen exposure in women with endometrial cancer undergoing in vitro fertilization using an aromatase inhibitor. DESIGN:Prospective case series. SETTING:Academic center for reproductive medicine. PATIENT(S):Endometrial carcinoma patients presenting for fertility preservation or fresh embryo tra...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2006.12.068
更新日期:2007-09-01 00:00:00
abstract:OBJECTIVE:To determine if the addition of fibrin sealant to incision closure in a rabbit uterine horn myomectomy model affects adhesion formation or strength of incision closure. DESIGN:Prospective randomized controlled trial. SETTING:Academic research center. ANIMAL(S):New Zealand white female rabbits. INTERVENTIO...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2005.07.1337
更新日期:2006-04-01 00:00:00
abstract:OBJECTIVE:To determine if pentoxifylline has an in vitro effect on human sperm motility in subjects with normal semen analysis. DESIGN:Prospective, longitudinal study of the effect of pentoxifylline on normospermic semen samples using computerized analysis. SETTING:The Assisted Conception Unit, Royal Maternity Hospit...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)55708-2
更新日期:1993-02-01 00:00:00
abstract:OBJECTIVE:To show the responsiveness of tissue-engineered human endometrial stroma to combinations of hormones that mimic the secretory and menstrual phases of the cycle. DESIGN:In vitro experimental study. SETTING:University uterine biology research laboratory. PATIENT(S):None. INTERVENTION(S):Telomerase immortali...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2012.01.098
更新日期:2012-04-01 00:00:00
abstract::The results of reinsemination of 150 morphologically mature oocytes that failed to fertilize within 15 to 20 hours after initial insemination were evaluated. Only 41 oocytes (27.3%) were fertilized after reinsemination, which is significantly lower than the percentage obtained after initial insemination (74%). However...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)49097-7
更新日期:1986-01-01 00:00:00
abstract:OBJECTIVE:To determine the effect of sonographer experience during ultrasound guided embryo transfer on pregnancy outcomes. DESIGN:Retrospective chart review. SETTING:A university-based academic practice. PATIENT(S):A total of 319 women who underwent in vitro fertilization and embryo transfer (IVF-ET) from the site-...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.07.1743
更新日期:2009-09-01 00:00:00
abstract:OBJECTIVE:To determine the human endometrial transcriptome during embryonic implantation. DESIGN:Case report. SETTING:Tertiary fertility center. PATIENT(S):A 24-year-old woman who inadvertently became pregnant during an endometrial biopsy procedure. INTERVENTION(S):An endometrial biopsy was performed with a Pipelle...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2009.08.057
更新日期:2010-01-01 00:00:00
abstract::In 115 patients (group I) in which normal liquefaction of semen occurred, the fertilization rate of the yielded oocytes was 71.2% after standard in vitro fertilization procedure, and the viable pregnancy rate per patient per cycle was 13.0%. In a comparable group of 26 patients (group II), in which semen liquefaction ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)60444-2
更新日期:1989-01-01 00:00:00
abstract::Danazol was found to possess androgenic and glucocorticoid activity in rat bioassays. In contrast, danazol displayed no significant estrogenic activity. In support of these findings, danazol bound to the 8 S androgen receptor of rat prostate cytosol and to the glucocorticoid receptor of rat liver cytosol, but danazol ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)43820-3
更新日期:1979-02-01 00:00:00
abstract:OBJECTIVE:To evaluate interrelationships between levels of insulin-like growth factor I (IGF-I), insulin-like growth factor binding protein (IGFBP-I), and ovarian steroids in late preovulatory follicular fluid (FF) after pituitary desensitization with GnRH agonist and controlled ovarian hyperstimulation. DESIGN:Follic...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)57179-9
更新日期:1994-12-01 00:00:00
abstract:OBJECTIVE:To assess the effects of age on the hormonal, metabolic, and ultrasonographic features of polycystic ovary syndrome (PCOS). DESIGN:Observational study. SETTING:University department of obstetrics and gynecology. PATIENT(S):Patients with PCOS (n = 1,212) and healthy women (n = 254). INTERVENTION(S):None. ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2011.11.041
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVE:The aim of the International Endogene Study is to discover genes that influence susceptibility to endometriosis. DESIGN:The study brings together two research groups based in Australia and the United Kingdom that independently have been collecting families for linkage analysis and candidate gene studies. Bot...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(02)03341-1
更新日期:2002-10-01 00:00:00
abstract::We report a patient undergoing hMG-induced superovulation who demonstrated delayed excretion of hCG, originally believed to be because of successive biochemical pregnancies. However, sequential hCG titers after administration of exogenous hCG demonstrated a longer than normal half-life for the excretion of hCG in this...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)54618-4
更新日期:1991-10-01 00:00:00
abstract:OBJECTIVES:To examine all case reports and studies of empty follicle syndrome (EFS) that have been published since the condition was first reported, in an attempt to identify trends or common features that may expose possible risk or causative factors. DESIGN:Systematic review of all available literature obtained from...
journal_title:Fertility and sterility
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.fertnstert.2007.07.1312
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVE:To assess the utility of endometrial thickness, echogenic endometrial pattern, and uterine artery impedance measured as pulsativity index in predicting implantation. DESIGN:Prospective case-controlled study of infertile patients undergoing assisted reproductive technologies (ARTs). PATIENTS:Four hundred fiv...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章
doi:10.1016/s0015-0282(16)57065-4
更新日期:1994-11-01 00:00:00
abstract::Although the general trend for delaying childbearing is generally viewed as causing infertility, its consequences on the interpregnancy interval have been unknown. A study of birth records for Swiss married women from 1969 to 2006 revealed that the woman's age at first birth has increased from 25.0 to 30.1 years, wher...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2009.05.078
更新日期:2009-12-01 00:00:00
abstract::Hypoxia downregulated the concentration of endostatin in the culture media of human endometrial stromal cells but did not affect the messenger (m)RNA expression of collagen XVIII. Both mRNA and protein expression of vascular endothelial growth factor were upregulated in a hypoxic condition. ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2004.03.032
更新日期:2004-09-01 00:00:00
abstract::Eight castrate, estrogen-replaced women were given 200 mg spironolactone daily for 4 weeks. The response of plasma dehydroepiandrosterone sulfate (DHEAS), testosterone (T), and androstenedione (delta 4A), all indicators of adrenal C19-steroid production, varied greatly among individuals. Sixteen women with idiopathic ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)59346-7
更新日期:1987-08-01 00:00:00
abstract:OBJECTIVE:To report the birth of a healthy female infant from a father with nonmosaic Klinefelter syndrome (KS) and document the experience of men with KS undergoing assisted conception. DESIGN:Retrospective. SETTING:Private IVF center. PATIENT(S):Twelve couples with male factor infertility due to Klinefelter syndro...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(03)01157-9
更新日期:2003-10-01 00:00:00
abstract::This study examined coping with infertility and how coping is related to depression for men and women. Results showed that both men and women who engage in a disproportionate degree of escape/avoidance behavior and acceptance of responsibility for infertility were more vulnerable to symptoms of depression. ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2005.09.020
更新日期:2006-03-01 00:00:00
abstract:OBJECTIVE:To describe a case of early pregnancy failure in a patient who was not an optimal candidate for suction aspiration because of her body habitus and history of a myocardial infarction that was treated medically with misoprostol. DESIGN:Case report. SETTING:Academic tertiary-care hospital. PATIENT:A 43-year-o...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2006.11.010
更新日期:2007-07-01 00:00:00
abstract::Certain conclusions may be drawn from the present review: 1. Synthetic FSH/LH-RH may induce ovulation; therefore, a therapeutic effect has been established in some cases of anovulatory infertility, but it is still difficult to assess the correct dose of FSH/LH-RH because of individual variations in response. 2. Gonado...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)42188-6
更新日期:1976-11-01 00:00:00
abstract:OBJECTIVE:To investigate whether antitrophoblast antibodies are associated with unexplained recurrent miscarriages, we used choriocarcinoma cells JEG-3, since these cells are negative for class I and II antigens, but they do express HLA-G, resembling an antigen expression of endovascular and interstitial trophoblasts. ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2011.11.014
更新日期:2012-02-01 00:00:00
abstract:OBJECTIVE:To report on chronic urinary retention after surgery for deep endometriosis and the possible risk factors for this complication. DESIGN:Descriptive study. SETTING:University hospital. PATIENT(S):Four patients with deep endometriosis who developed this complication. INTERVENTION(S):Laparoscopic surgery, in...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2010.07.1043
更新日期:2011-02-01 00:00:00