Abstract：
OBJECTIVE:To assess whether heart rate variability (HRV) at rest and during sympathetic stimulation is disturbed in patients with different polycystic ovary syndrome (PCOS) phenotypes in comparison to healthy controls. DESIGN:Cross-sectional study. SETTING:University hospital. PATIENT(S):Thirty women with classic, anovulatory PCOS, 16 women with ovulatory PCOS, and 23 age-paired women with regular and proven ovulatory cycles. INTERVENTION(S):Anthropometric and hormonal evaluation and analysis of HRV (time and frequency domain HRV indices) at rest and after a mental stress test. MAIN OUTCOME MEASURE(S):Difference between HRV components during rest and stress. RESULT(S):Mean age was 22.80 ± 5.80 years in patients with classic PCOS, 19.81 ± 6.43 years in ovulatory PCOS, and 22.65 ± 5.89 years in controls. During mental stress, patients with classic PCOS showed lower HRV response when compared with the control group, even after adjustment for body mass index (BMI) and age. When patients with classic and ovulatory PCOS were considered together, total T levels were inversely associated with the low frequency component, low frequency/high frequency ratio, and the difference between high frequency response at rest and after the stress test. CONCLUSION(S):Young patients with the classic PCOS phenotype have an impaired autonomic modulation in response to sympathetic stimulation that is typical of considerably older women, or of advanced age.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Di Domenico K,Wiltgen D,Nickel FJ,Magalhães JA,Moraes RS,Spritzer PMdoi
10.1016/j.fertnstert.2012.08.049subject
Has Abstractpub_date
2013-01-01 00:00:00pages
286-292issue
1eissn
0015-0282issn
1556-5653pii
S0015-0282(12)02137-1journal_volume
99pub_type
杂志文章abstract：OBJECTIVE:To measure the effect of competition among fertility centers on pregnancy and high-order multiple (HOM) gestation rates after IVF. DESIGN:Retrospective cohort study. SETTING:Four hundred eight fertility clinics registered with the Society for Assisted Reproductive Technology as providing IVF services in 200...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2004.10.048
更新日期：2005-05-01 00:00:00
abstract：INTRODUCTION:Polycystic ovary syndrome (PCOS) is a highly prevalent disorder among postmenarcheal premenopausal women, accounting for much of anovulatory infertility, and it is associated with several comorbidities. The natural history of PCOS, as well as hypotheses regarding its etiology, facilitates employment of the...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2005.09.066
更新日期：2006-07-01 00:00:00
abstract：OBJECTIVE:To evaluate the effect of supernumerary preovulatory follicular reduction as an approach to avoid multiple pregnancies in ovulation induction or superovulation cycles. DESIGN:Retrospective study. SETTING:Tertiary referral center. PATIENT(S):In 26 cycles, 24 patients underwent ovulation induction or superov...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(01)02379-2
更新日期：2001-10-01 00:00:00
abstract：:A recent survey of American Society for Reproductive Medicine (ASRM) members indicates that they express a commitment to professional standards and a desire for advocacy. Their attitudes echo traditional values of professionalism, upon which ASRM should capitalize. ...
journal_title：Fertility and sterility
pub_type： 评论,杂志文章
doi：10.1016/j.fertnstert.2004.01.052
更新日期：2004-09-01 00:00:00
abstract：OBJECTIVE:To test the effects of steroid-containing media such as follicular fluid (FF) and serum and of steroid-free but human protein-rich medium on hyperactivation (HA) of human spermatozoa with and without a preincubation period. DESIGN:Analysis of HA using a computer-aided sperm analysis system. SETTING:Academic...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)57191-x
更新日期：1994-12-01 00:00:00
abstract：:Follicular development was followed by echography during 18 menstrual cycles in 10 women volunteers. Results were correlated with changes in serum hormone levels, basal body temperature curves, and cervical mucus changes. The average follicular growth as measured from the time of echographic visualization was 0.3 cm/d...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)44592-9
更新日期：1980-03-01 00:00:00
abstract：OBJECTIVE:To determine the role of parental and biological factors on the U.S. male birth fraction from 1964 through 1988. DESIGN:Logistic regression on annual U.S. male births by race group. SETTING:Population-based data. PATIENT(S):Live births in the United States 1964 through 1988. INTERVENTION(S):None. MAIN OU...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(99)00576-2
更新日期：2000-03-01 00:00:00
abstract：:Recent in vitro studies implicate the ovary as an extra-hepatic source of insulin-like growth factors (IGFs) with production regulated by gonadotropins and local steroids. Because previous studies have failed to show any significant variations in IGF levels in peripheral blood during the menstrual cycle, we measured t...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)53221-x
更新日期：1990-01-01 00:00:00
abstract：:Anatomic distances along retroperitoneal, inguinal, and infrainguinal segments of the vas deferens were measured in 14 formalin fixed cadavers and in 15 recently postmortem males. There were no significant differences in segment lengths between the two groups nor between the right and left vasa. Data from the recent p...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)53959-4
更新日期：1990-11-01 00:00:00
abstract：OBJECTIVE:To study single sperm boar motility using electrical impedance measurements in a microfluidic system. DESIGN:Comparison of the optical data and electrical impedance data. SETTING:Research laboratory at a university. ANIMAL(S):Boar semen sample were used. INTERVENTION(S):A microfluidic system is developed ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2016.05.008
更新日期：2016-09-01 00:00:00
abstract：:In this prospective case-control study, we determined the role of surface-enhanced laser desorption and ionization time-of-flight mass spectrometry in the detection of histologically proven endometriosis. In the plasma of the group with endometriosis, there were 20 different protein peaks, and the classifier showed a ...
journal_title：Fertility and sterility
pub_type： 信件
doi：10.1016/j.fertnstert.2006.08.095
更新日期：2007-04-01 00:00:00
abstract：OBJECTIVE:To evaluate the association between genetic variants in Ser-Arg (SR) protein-coding genes and the susceptibility of nonobstructive azoospermia (NOA) in Chinese men. DESIGN:Case-control study. SETTING:State Key Laboratory of Reproductive Medicine in Nanjing Medical University conducted the genotyping and exa...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2014.02.033
更新日期：2014-06-01 00:00:00
abstract：:In this prospective, follow-up study of 102 high-risk oocyte donors in their luteal phase, we found a complete absence of ovarian hyperstimulation syndrome (no signs of hemoconcentration or ascites) after the donors were triggered with a gonadotropin releasing-hormone (GnRH) agonist. Due to its powerful preventive eff...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/j.fertnstert.2009.08.036
更新日期：2010-05-01 00:00:00
abstract：:The use of modified natural-cycle in vitro fertilization (IVF) is a valuable alternative to controlled ovarian hyperstimulation in young poor responders and should be considered in patients who require IVF and demonstrate endocrinologic evidence of ovarian aging and in those who have had one or two canceled controlled...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2011.09.052
更新日期：2011-11-01 00:00:00
abstract：OBJECTIVE:To determine the effects of tibolone and continuous combined HRT (ccHRT) on parameters in the clotting cascade. DESIGN:Randomized, double-blind study. SETTING:Hemostasis unit of a university hospital clinic in Germany. PATIENT(S):Sixty healthy postmenopausal women. INTERVENTION(S):Twenty-nine subjects wer...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/s0015-0282(00)00587-2
更新日期：2000-07-01 00:00:00
abstract：:Peritoneal fluid and serum were collected from 78 patients at the time of laparoscopy. Twenty-two were fertile controls (CTL), and 56 were infertility patients, who were subdivided into three main groups: endometriosis (EMS), pelvic adhesions (ADH), and ovarian dysfunction (OvDF). Based on control group data, biochemi...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)48020-9
更新日期：1984-08-01 00:00:00
abstract：:We found that four polymorphisms in the protein L-isoaspartyl-O-methyltransferase (PCMT1) gene, encoding a protein repair enzyme, are associated with premature ovarian failure (POF). All four polymorphisms were in strong linkage disequilibrium. The frequencies of two haplotypes were statistically significantly differe...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.03.078
更新日期：2009-04-01 00:00:00
abstract：:Fertilization characteristics of 152 consecutively obtained oocytes in an in vitro fertilization (IVF) program employing only natural and clomiphene citrate-induced cycles were retrospectively analyzed. Fertilization occurred significantly more often (1) in women with tubal infertility, (2) in spontaneous cycles, and ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)53764-9
更新日期：1990-09-01 00:00:00
abstract：OBJECTIVE:To investigate for differences in reproductive hormone levels in male relatives of women with polycystic ovary syndrome (PCOS). DESIGN:Cross-sectional study. SETTING:Academic medical center. PATIENT(S):Sixty-three fathers and 66 brothers of women with PCOS as well as two groups of control men of comparable...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2016.03.029
更新日期：2016-07-01 00:00:00
abstract：OBJECTIVE:To evaluate the efficiency of oocyte donation cycles using egg "cryo-banking." DESIGN:Study conditions for vitrified/warmed oocytes for 20 non-autologous recipients (from 10 donors) were set prospectively, and outcomes of it were later compared retrospectively to nine fresh donations cycles. SETTING:Private...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/j.fertnstert.2008.06.005
更新日期：2009-08-01 00:00:00
abstract：:A simple, sensitive, and reliable single-unit nonradioactive method for the detection of human chorionic gonadotropin (hCG) in concentrated urine and the diagnosis of early pregnancy is reported. This unit, presently termed the Ayerst pregnancy test kit (APTK), consists of four components: a sampler-filter paper cone,...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)44299-8
更新日期：1979-10-01 00:00:00
abstract：OBJECTIVE:To describe novel embryo features capable of predicting implantation potential as input data for an artificial neural network (ANN) model. DESIGN:Retrospective cohort study. SETTING:University-affiliated private IVF center. PATIENT(S):This study included 637 patients from the oocyte donation program who un...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2020.08.023
更新日期：2020-12-01 00:00:00
abstract：:The ability of freshly collected and frozen human spermatozoa to migrate in round capillary tubes containing specially formulated polyacrylamide gel was investigated, using 33 ejaculates from 27 donors. Each semen sample was divided; one portion was left undiluted, and the other portion was diluted to 50 x 10(6) sperm...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)46280-1
更新日期：1982-05-01 00:00:00
abstract：OBJECTIVE:To determine the aneuploidy rate in embryos of women with idiopathic recurrent miscarriages and to evaluate whether preimplantation genetic diagnosis for aneuploidy screening could be a feasible approach to improve the possibility of successful pregnancy in these couples. DESIGN:Prospective cohort study. SE...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2004.06.071
更新日期：2005-02-01 00:00:00
abstract：OBJECTIVE:To evaluate which clinical characteristics influence early maternal β-human chorionic gonadotropin (hCG) and progesterone levels in in vitro fertilization (IVF) pregnancies. DESIGN:Retrospective cohort analysis. SETTING:Academic medical center. PATIENT(S):Women with a live birth after single-blastocyst emb...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2018.08.047
更新日期：2018-12-01 00:00:00
abstract：:The hyperandrogenic-insulin-resistant acanthosis nigricans syndrome affects between 2% and 5% of hirsute women and is characterized by INS resistance, elevated INS levels, acanthosis nigricans, and androgen excess. These patients' response to therapy is unclear, although long-acting GnRH-a suppression has been propose...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1994-03-01 00:00:00
abstract：:Under pressure from involved families and time limitations, Israeli judges tend to authorize postmortem sperm retrieval and freezing, even in unmarried men and in contradiction to current, albeit non-legally binding, guidelines of the Attorney General. Postmortem sperm retrieval in our institution (2003 to June 2009) ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2009.10.035
更新日期：2010-08-01 00:00:00
abstract：:In young women receiving chemotherapy for Hodgkin's disease, the combined use of triptorelin and tibolone cotreatment may be a useful tool for preserving ovarian function because all but three (10%) of the women in this treatment group returned to spontaneous ovulation and menses, in contrast to 23% of subjects in the...
journal_title：Fertility and sterility
pub_type： 信件
doi：10.1016/j.fertnstert.2006.10.004
更新日期：2007-03-01 00:00:00
abstract：OBJECTIVE:To investigate the direct effects of sodium nitroprusside, a nitric oxide donor, on the fertilizing ability of human spermatozoa in vitro. DESIGN:Prospective, controlled in vitro study. SETTING:IVF Unit, Medical College Hospital. PATIENT(S):Women undergoing conventional IVF. INTERVENTION(S):Human spermato...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(97)00537-2
更新日期：1998-03-01 00:00:00
abstract：:Two-cell mouse embryos were cultured in Ham's F-10 medium (Gibco, Grand Island, NY) supplemented with various concentrations of transferrin, insulin, epidermal growth factor, platelet-derived growth factor, or fibroblast growth factor. Rates of development and the cell numbers per blastocyst were compared between embr...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)54082-5
更新日期：1991-01-01 00:00:00
