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Association between polymorphisms in the protein L-isoaspartate (D-aspartate) O-methyltransferase gene and premature ovarian failure.

Abstract：

:We found that four polymorphisms in the protein L-isoaspartyl-O-methyltransferase (PCMT1) gene, encoding a protein repair enzyme, are associated with premature ovarian failure (POF). All four polymorphisms were in strong linkage disequilibrium. The frequencies of two haplotypes were statistically significantly different between the POF group and the matched control group.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Pyun JA,Kang H,Lee SK,Kim MH,Kwack K

doi

10.1016/j.fertnstert.2008.03.078

subject

Has Abstract

pub_date

2009-04-01 00:00:00

pages

1362-5

issue

4 Suppl

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(08)00753-X

journal_volume

91

pub_type

杂志文章

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