Criteria, prevalence, and phenotypes of polycystic ovary syndrome.

Abstract:

:Polycystic ovary syndrome (PCOS) is a highly prevalent disorder effecting reproductive-aged women worldwide. This article addresses the evolution of the criteria used to diagnosis PCOS; reviews recent advances in the phenotypic approach, specifically in the context of the extended Rotterdam criteria; discusses limitations of the current criteria used to diagnosis, particularly when studying adolescents and women in the peri- and postmenopause; and describes significant strides made in understanding the epidemiology of PCOS. This review recognizes that although there is a high prevalence of PCOS, there is increased variability when using Rotterdam 2003 criteria, owing to limitations in population sampling and approaches used to define PCOS phenotypes. Last, we discuss the distribution of PCOS phenotypes, their morbidity, and the role that referral bias plays in the epidemiology of this syndrome.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Lizneva D,Suturina L,Walker W,Brakta S,Gavrilova-Jordan L,Azziz R

doi

10.1016/j.fertnstert.2016.05.003

subject

Has Abstract

pub_date

2016-07-01 00:00:00

pages

6-15

issue

1

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(16)61232-3

journal_volume

106

pub_type

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