Introduction: menopausal hormone therapy: where are we today?

Abstract:

:In this Views and Reviews section, the authors present the most updated information on menopausal hormone therapy (MHT) and an individualized treatment approach. Care of women through the menopausal transition and post-menopausally requires physicians to integrate multi-organ implications of MHT and understand the full-range of treatment alternatives.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Cedars MI

doi

10.1016/j.fertnstert.2014.02.026

subject

Has Abstract

pub_date

2014-04-01 00:00:00

pages

885-6

issue

4

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(14)00179-4

journal_volume

101

pub_type

  • Ultrasonographic predictors of implantation after assisted reproduction.

    abstract:OBJECTIVE:To assess the utility of endometrial thickness, echogenic endometrial pattern, and uterine artery impedance measured as pulsativity index in predicting implantation. DESIGN:Prospective case-controlled study of infertile patients undergoing assisted reproductive technologies (ARTs). PATIENTS:Four hundred fiv...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0015-0282(16)57065-4

    authors: Coulam CB,Bustillo M,Soenksen DM,Britten S

    更新日期:1994-11-01 00:00:00

  • Blastocyst formation, pregnancy, and birth derived from human oocytes cryopreserved for 5 years.

    abstract:OBJECTIVE:To report a live birth after the transfer of a single blastocyst derived from a human oocyte cryopreserved for 5 years. DESIGN:Case report. SETTING:Private assisted reproduction center. PATIENT(S):A 39-year-old woman with tubal infertility and her partner with male-related infertility. INTERVENTION(S):Ooc...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2008.01.106

    authors: Parmegiani L,Fabbri R,Cognigni GE,Bernardi S,Pocognoli P,Filicori M

    更新日期:2008-11-01 00:00:00

  • Spontaneous apoptosis of endometrial tissue is impaired in women with endometriosis.

    abstract:OBJECTIVE:To evaluate spontaneous apoptosis in single-cell suspensions of eutopic and ectopic endometrium from women with endometriosis and in eutopic endometrium from fertile controls without endometriosis. DESIGN:Paired specimens of eutopic and ectopic endometrial tissue from patients with endometriosis and eutopic ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(98)00073-9

    authors: Gebel HM,Braun DP,Tambur A,Frame D,Rana N,Dmowski WP

    更新日期:1998-06-01 00:00:00

  • Sperm deoxyribonucleic acid damage in normozoospermic men is related to age and sperm progressive motility.

    abstract:OBJECTIVE:To evaluate sperm DNA fragmentation in normozoospermic male partners of couples undergoing infertility evaluation. DESIGN:Retrospective cohort study. SETTING:Clinical andrology laboratory. PATIENT(S):A total of 1,974 consecutive normozoospermic men selected from a larger cohort of 4,345 consecutive, nonazo...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2014.02.006

    authors: Belloc S,Benkhalifa M,Cohen-Bacrie M,Dalleac A,Amar E,Zini A

    更新日期:2014-06-01 00:00:00

  • Effects of immunization with the beta-subunit of ovine luteinizing hormone on corpus luteum function in the rhesus monkey.

    abstract::Rhesus monkeys immunized with the beta-subunit of ovine luteinizing hormone (oLHbeta) developed circulating antibodies which cross-reacted strongly with rhesus monkey chorionic gonadotropin. Normal ovulatory cycles continued, but the fertility of immunized monkeys as compared with that of controls was significantly re...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:

    authors: Thau RB,Sundaram K,Thornton YS,Seidman LS

    更新日期:1979-02-01 00:00:00

  • Environmentally relevant levels of bisphenol A affect uterine decidualization and embryo implantation through the estrogen receptor/serum and glucocorticoid-regulated kinase 1/epithelial sodium ion channel α-subunit pathway in a mouse model.

    abstract:OBJECTIVE:To investigate whether bisphenol A (BPA) exposure is associated with uterine decidualization and embryo implantation failure in mice. DESIGN:Experimental animal study and in vitro study. SETTING:University-based infertility center. ANIMAL(S):ICR mice. INTERVENTION(S):Mice treated with different doses of B...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2017.12.003

    authors: Yuan M,Hu M,Lou Y,Wang Q,Mao L,Zhan Q,Jin F

    更新日期:2018-04-01 00:00:00

  • Comparison of microdissection testicular sperm extraction, conventional testicular sperm extraction, and testicular sperm aspiration for nonobstructive azoospermia: a systematic review and meta-analysis.

    abstract:OBJECTIVE:To investigate the relative differences in outcomes among microdissection testicular sperm extraction (micro-TESE), conventional testicular sperm extraction (cTESE), and testicular sperm aspiration (TESA) in men with nonobstructive azoospermia. DESIGN:Systematic review and meta-analysis. SETTING:Outpatient ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.fertnstert.2015.07.1136

    authors: Bernie AM,Mata DA,Ramasamy R,Schlegel PN

    更新日期:2015-11-01 00:00:00

  • Ovarian responses to menopausal gonadotropins in groups of patients with differing basal growth hormone levels.

    abstract:OBJECTIVE:To investigate the relationship between endogenous serum levels of human growth hormone (hGH) and ovarian response to human menopausal gonadotropins (hMG). DESIGN:Retrospective analysis of patient response to hMG. SETTING:Center for assisted reproductive technology. PATIENTS:Eighty women who had undergone ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)55133-4

    authors: Stone BA,Marrs RP

    更新日期:1992-07-01 00:00:00

  • Reinsemination by intracytoplasmic sperm injection of 1-day-old oocytes after complete conventional fertilization failure.

    abstract:OBJECTIVE:To analyze the efficacy of intracytoplasmic sperm injection (ICSI) for "rescue" of failed conventional insemination cycles. DESIGN:Retrospective clinical study. SETTING:Private infertility clinic. PATIENT(S):Fifty-four couples with non-male factor infertility undergoing routine IVF within our clinic. INTE...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(97)00223-9

    authors: Morton PC,Yoder CS,Tucker MJ,Wright G,Brockman WD,Kort HI

    更新日期:1997-09-01 00:00:00

  • Potential chemoprotective effect of melatonin in cyclophosphamide- and cisplatin-induced testicular damage in rats.

    abstract:OBJECTIVE:To evaluate the effect of melatonin on cyclophosphamide (CP)- and cisplatin-induced testicular toxicity with use of sperm parameters and biochemical and histopathologic approaches. DESIGN:Experimental study. SETTING:Vakif Gureba Hospital, Istanbul, Turkey. ANIMALS:Six-week-old adult male Wistar albino rats...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2008.07.1758

    authors: Ilbey YO,Ozbek E,Simsek A,Otunctemur A,Cekmen M,Somay A

    更新日期:2009-09-01 00:00:00

  • Endometrial dating in the conception cycle.

    abstract:OBJECTIVE:To investigate endometrial dating during the conception cycle. DESIGN:Endometrial biopsies of the last half of the luteal phase of conception cycles were dated based on urinary luteinizing hormone (LH) surges. SETTING:Endometrial samples were obtained from women attending the fertility clinic of the Departm...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:

    authors: Andoh K,Mizunuma H,Nakazato Y,Yamada K,Michishita M,Ibuki Y

    更新日期:1992-12-01 00:00:00

  • Weak linkage in androgen receptor: identification of mutation-prone points.

    abstract:OBJECTIVE:Mutation within androgen receptor (AR) can be seen. Presently, prediction of protein nanostructure and function is a great challenge in the proteomics and structural genomics era. To identify the points vulnerable to mutation is a new trend to expand the knowledge on disorders in genomic and proteomic level o...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2007.06.089

    authors: Wiwanitkit V

    更新日期:2009-01-01 00:00:00

  • Serum sex hormone-binding globulin levels show too much variability to be used effectively as a screening marker for insulin resistance in women with polycystic ovary syndrome.

    abstract:OBJECTIVE:To evaluate the relationship between serum sex hormone-binding globulin (SHBG) and parameters of insulin sensitivity in women with polycystic ovary syndrome (PCOS) and controls, and determine the feasibility of using SHBG levels to predict insulin resistance. DESIGN:Evaluation of a prospectively collected da...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.fertnstert.2006.02.108

    authors: Dahan MH,Goldstein J

    更新日期:2006-10-01 00:00:00

  • Effect of follicle-stimulating hormone upon estrogen and progesterone secretion by cultures of monkey granulosa cells recovered during the periovulatory period.

    abstract::For determination of how exposure of the monkey follicle to the preovulatory luteinizing hormone (LH)/follicle-stimulating hormone (FSH) surge alters its responsiveness to FSH in terms of estrogen and progesterone secretory ability, monkey thecal tissue and granulosa cells were harvested prior to and during the midcyc...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)48087-8

    authors: Channing CP,Reichert LE Jr

    更新日期:1984-09-01 00:00:00

  • Requirements for research investigations to clarify the relationships and management of menstrual abnormalities in women with hemostatic disorders.

    abstract::This article highlights a comprehensive range of research investigations which are required to clarify the relationships between the symptom of excessively heavy menstrual bleeding and different disorders of systemic hemostasis and their management. The need for these investigations was stimulated by an international ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,评审

    doi:10.1016/j.fertnstert.2005.07.1268

    authors: Fraser IS,Bonnar J,Peyvandi F

    更新日期:2005-11-01 00:00:00

  • The likelihood of finding mature sperm cells in men with AZFb or AZFb-c deletions: six new cases and a review of the literature (1994-2010).

    abstract:OBJECTIVE:To reassess the predictive value of detecting sperm cells in men with AZFb or AZFb-c deletions. DESIGN:Retrospective analysis of previously reported men with AZFb or AZFb-c deletions and the addition of six new cases. SETTING:Fertility institution. PATIENT(S):Men with both sequence tagged site marker ident...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,评审

    doi:10.1016/j.fertnstert.2011.01.162

    authors: Kleiman SE,Yogev L,Lehavi O,Hauser R,Botchan A,Paz G,Yavetz H,Gamzu R

    更新日期:2011-05-01 00:00:00

  • Effects of pentoxifylline on human sperm motility in normospermic individuals using computer-assisted analysis.

    abstract:OBJECTIVE:To determine if pentoxifylline has an in vitro effect on human sperm motility in subjects with normal semen analysis. DESIGN:Prospective, longitudinal study of the effect of pentoxifylline on normospermic semen samples using computerized analysis. SETTING:The Assisted Conception Unit, Royal Maternity Hospit...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)55708-2

    authors: Lewis SE,Moohan JM,Thompson W

    更新日期:1993-02-01 00:00:00

  • The inhibitory effects of danazol, danazol metabolites, gestrinone, and testosterone on the growth of human endometrial cells in vitro.

    abstract::Danazol and gestrinone are effective drugs in the treatment of endometriosis. Their mechanism of action remains uncertain, but may be related to their androgenic activity. The authors examined the effect of danazol on human endometrial cells cultured in vitro, its two major metabolites, ethisterone and 2 hydroxymethyl...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)59706-4

    authors: Rose GL,Dowsett M,Mudge JE,White JO,Jeffcoate SL

    更新日期:1988-02-01 00:00:00

  • Effect of levothyroxine treatment on in vitro fertilization and pregnancy outcome in infertile women with subclinical hypothyroidism undergoing in vitro fertilization/intracytoplasmic sperm injection.

    abstract:OBJECTIVE:To investigate whether levothyroxine (LT4) treatment has beneficial effects on IVF results and pregnancy outcome in infertile patients with subclinical hypothyroidism undergoing IVF/intracytoplasmic sperm injection (ICSI). DESIGN:Prospective, randomized trial. SETTING:University-affiliated infertility clini...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.fertnstert.2010.12.004

    authors: Kim CH,Ahn JW,Kang SP,Kim SH,Chae HD,Kang BM

    更新日期:2011-04-01 00:00:00

  • Endometrial infusion of human chorionic gonadotropin at the time of blastocyst embryo transfer does not impact clinical outcomes: a randomized, double-blind, placebo-controlled trial.

    abstract:OBJECTIVE:To determine whether endometrial hCG infusion at the time of human blastocyst transfer impacts implantation rates. DESIGN:Randomized double-blinded placebo-controlled trial. SETTING:Academic. PATIENT(S):Infertile couples with the female partner less than 43 years old (n = 300) undergoing fresh or frozen ET...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.fertnstert.2014.08.006

    authors: Hong KH,Forman EJ,Werner MD,Upham KM,Gumeny CL,Winslow AD,Kim TJ,Scott RT Jr

    更新日期:2014-12-01 00:00:00

  • The impairment of reproduction in db/db mice is not mediated by intraovarian defective leptin signaling.

    abstract:OBJECTIVE:To demonstrate whether leptin modulates reproduction by a direct effect within the ovary. DESIGN:Animal model. SETTING:National Key Laboratory of Infertility. ANIMAL(S):Adult female db/db mice. INTERVENTION(S):Adult littermate wild-type (WT) and diabetic (db) leptin receptor (LR) mutant female mice were m...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2012.01.126

    authors: Zhang Y,Hu M,Ma H,Qu J,Wang Y,Hou L,Liu L,Wu XK

    更新日期:2012-05-01 00:00:00

  • Pubertal development of the first cohort of young adults conceived by in vitro fertilization in the United States.

    abstract:OBJECTIVE:To characterize pubertal development of the first generation of young adults born as a result of in vitro fertilization (IVF). Demographic, clinical, and body size characteristics were examined regarding developmental milestones. DESIGN:Cross-sectional. SETTING:Academic center. PATIENT(S):Young adults (18-...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2010.04.057

    authors: Beydoun HA,Sicignano N,Beydoun MA,Bocca S,Stadtmauer L,Oehninger S

    更新日期:2011-02-01 00:00:00

  • Protein expression profiling of endometriosis: validation of 2-mm tissue microarrays.

    abstract::Tissue microarrays (TMAs) are useful tools for studying protein expression in endometriosis. Tissue microarray analyses of immunohistochemical profiles of estrogen receptor-alpha and P receptor corroborate previously published results from the use of conventional immunohistochemistry, thus validating TMA use in endome...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2004.06.044

    authors: Kamat AA,Younes PS,Sayeeduddin M,Wheeler TM,Simpson JL,Agoulnik AI

    更新日期:2004-12-01 00:00:00

  • Influencing factors of adhesion development and the efficacy of adhesion-preventing agents in patients undergoing laparoscopic myomectomy as evaluated by a second-look laparoscopy.

    abstract:OBJECTIVE:To examine the factors influencing the development of adhesions after laparoscopic myomectomy (LM) and the efficacy of adhesion-preventing agents. DESIGN:Prospective nonrandomized study. SETTING:University-affiliated hospital. PATIENT(S):Three hundred seventy-two patients who underwent LM alone by the same...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.fertnstert.2007.05.021

    authors: Takeuchi H,Kitade M,Kikuchi I,Shimanuki H,Kumakiri J,Takeda S

    更新日期:2008-05-01 00:00:00

  • Characterization of exosomes in peritoneal fluid of endometriosis patients.

    abstract:OBJECTIVE:To demonstrate the feasibility of studying exosomes directly from peritoneal fluid, we isolated exosomes from endometriosis patient samples and from controls, and characterized their cargo. DESIGN:Case-control experimental study. SETTING:Academic clinical center. PATIENT (S):Women with and without endometr...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2019.09.032

    authors: Nazri HM,Imran M,Fischer R,Heilig R,Manek S,Dragovic RA,Kessler BM,Zondervan KT,Tapmeier TT,Becker CM

    更新日期:2020-02-01 00:00:00

  • Twice-frozen embryos are no detriment to pregnancy success: a retrospective comparative study.

    abstract:OBJECTIVE:To compare the pregnancy rates (PR) and live birth rates in once- versus twice-frozen ET treatment cycles in the same cohort of women. DESIGN:A retrospective study. SETTING:Fertility clinics, IVF Australia, New South Wales. PATIENT(S):The study population was all women who underwent thawing of twice-frozen...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2011.04.034

    authors: Koch J,Costello MF,Chapman MG,Kilani S

    更新日期:2011-07-01 00:00:00

  • Hyperprolactinemic male infertility.

    abstract::Serum prolactin was studied in 25 fertile and 127 infertile men. The latter included 91 oligospermic, 27 azoospermic, and 9 hypogonadotropic hypogonadal men. The mean prolactin level in all three groups of infertile men was significantly above that of the fertile group. There was no correlation among serum levels of f...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)42259-4

    authors: Segal S,Polishuk WZ,Ben-David M

    更新日期:1976-12-01 00:00:00

  • Comparison of techniques for the selection of bacteria-free sperm preparations.

    abstract::The authors compared the three most commonly used sperm preparation techniques--swim-up, fall-down, and Percoll gradient--for their ability to recover highly motile sperm and minimize bacterial contamination. Eleven human semen samples collected by masturbation were used and run in parallel with the three methods. A s...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)59481-3

    authors: Sun LS,Gastaldi C,Peterson EM,de la Maza LM,Stone SC

    更新日期:1987-10-01 00:00:00

  • Effect of human endometrial secretions on the metabolism of human spermatozoa.

    abstract::The interaction between human uterine secretions and human spermatozoa was studied. Secretions were obtained by washing the endometrial surfaces of normal uteri removed at surgery and collecting uterine fluid by incubating Millipore chambers in the uteri of volunteers. A microtechnique was devised for conducting metab...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)45259-3

    authors: Trifunac NP,Bernstein GS

    更新日期:1981-01-01 00:00:00

  • Elective single blastocyst transfer.

    abstract::This report describes our initial experience with elective single blastocyst transfer in 19 patients who had a mean age of 36.3 +/- 2.4 years. The ongoing pregnancy rate, 53% after the fresh embryo transfer and 68% when thaw cycles are included, suggests that single blastocyst transfer has a place in this relatively o...

    journal_title:Fertility and sterility

    pub_type: 信件

    doi:10.1016/j.fertnstert.2003.10.050

    authors: Milki AA,Hinckley MD,Westphal LM,Behr B

    更新日期:2004-06-01 00:00:00