Abstract:
:Peritoneal fluid and serum were collected from 78 patients at the time of laparoscopy. Twenty-two were fertile controls (CTL), and 56 were infertility patients, who were subdivided into three main groups: endometriosis (EMS), pelvic adhesions (ADH), and ovarian dysfunction (OvDF). Based on control group data, biochemical criteria indicative of the presence of a stigma, S(+), were established: (1) serum progesterone (P) greater than or equal to 2 ng/ml, (2) peritoneal fluid P greater than or equal to 50 ng/ml, and (3) peritoneal fluid/serum ratio of P greater than or equal to 3. Direct visualization by laparoscopy showed that 21% CTL, 75% EMS, 69% ADH, and 56% OvDF subjects had luteinized unruptured follicle (LUF) syndrome. Biochemical criteria, however, demonstrated only 7% CTL, 37% EMS, 23% ADH, and 56% OvDF subjects had LUF. Peritoneal fluid estradiol (E2) and P concentrations and total content were significantly lower in LUF than in non-LUF patients, whereas serum E2 and P concentrations were not different between the two groups. Values for testosterone and androstenedione in peritoneal fluid and serum were similar between these two groups. Endometrial dating in LUF versus non-LUF patients were also similar. The usual indicators of ovulation, i.e., serum P, endometrial dating, and basal body temperature, failed to identify LUF. The diagnosis of LUF can be best made by P assay of peritoneal fluid and serum.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Lesorgen PR,Wu CH,Green PJ,Gocial B,Lerner LJdoi
10.1016/s0015-0282(16)48020-9subject
Has Abstractpub_date
1984-08-01 00:00:00pages
237-42issue
2eissn
0015-0282issn
1556-5653pii
S0015-0282(16)48020-9journal_volume
42pub_type
杂志文章abstract:OBJECTIVE:To evaluate the association between female cystic fibrosis (CF) carrier status and in vitro fertilization (IVF) response and outcomes. The presence of cystic fibrosis transmembrane conductance regulator (CFTR) gene mutations in male carriers has been associated with infertility, yet possible adverse effects o...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2014.07.1234
更新日期:2014-11-01 00:00:00
abstract::The PF environment is one that hosts the processes of ovulation, gamete transportation, fertilization, and early embryonic development. The cellular and acellular constituents of this dynamic fluid are in a constant interactive state, being influenced by the physiologic events of the menstrual cycle and pelvic disease...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/s0015-0282(16)59280-2
更新日期:1987-07-01 00:00:00
abstract:OBJECTIVE:To compare the semen quality and hormonal status between patients with testicular cancer and normal versus increased serum levels of beta-hCG. DESIGN:Retrospective study. SETTING:Academic research environment. PATIENT(S):All 203 patients with testicular cancer who required chemotherapy in the period 1995-2...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.03.016
更新日期:2009-06-01 00:00:00
abstract:OBJECTIVE:To study the incidence rate and hazard ratios of diabetes and prediabetes between women with PCOS and healthy subjects. DESIGN:Prospective population-based study. SETTING:Not applicable. PATIENT(S):Women with PCOS (n = 178) and eumenorrheic, nonhirsute, healthy women as controls (n = 1,524), all followed f...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2017.09.004
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVE:To determine if endometrial tissue specific complement (C) activation occurs in patients with endometriosis. DESIGN:Prospective. SETTING:University of Oklahoma Health Sciences Center, a tertiary care referral center. PATIENTS:Twenty-six women, 9 with endometriosis and 17 without endometriosis. INTERVENTIO...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1992-04-01 00:00:00
abstract:OBJECTIVE:To evaluate whether the efficacy of naltrexone administration in patients with hypothalamic amenorrhea correlates to the response to an acute naloxone test. DESIGN:Thirty patients with hypothalamic amenorrhea associated with weight loss were studied. After naloxone test (4 mg in bolus IV) patients were divid...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章
doi:10.1016/s0015-0282(16)57908-4
更新日期:1995-11-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of transforming growth factor (TGF)-beta1 on the extracellular signal-regulated kinase (ERK) and Smad pathway and the role of peroxisome proliferator-activated receptor (PPAR)-gamma in cultured human endometrial stromal cells. DESIGN:Experimental study. SETTING:Infertility center o...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2007.09.010
更新日期:2008-10-01 00:00:00
abstract::Women with classic congenital adrenal hyperplasia (CAH) can suffer from impaired fertility rates as a result of increased androgen secretion or impaired sex steroid production. In virilizing CAH forms, such as 21-hydroxylase and 11β-hydroxylase deficiency, the low reported pregnancy rate is mainly secondary to a dimin...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/j.fertnstert.2018.11.037
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:To determine the effects of tibolone and continuous combined HRT (ccHRT) on parameters in the clotting cascade. DESIGN:Randomized, double-blind study. SETTING:Hemostasis unit of a university hospital clinic in Germany. PATIENT(S):Sixty healthy postmenopausal women. INTERVENTION(S):Twenty-nine subjects wer...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s0015-0282(00)00587-2
更新日期:2000-07-01 00:00:00
abstract::A total of 82 patients underwent 106 cycles in which immature oocytes were recovered after hCG priming and transferred at blastocyst-stage. After transfer, the implantation rate was 26.8%, and the clinical pregnancy rate was 51.9%. We found that the oocytes retrieved after hCG priming in women with high risk of ovaria...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2006.11.027
更新日期:2007-06-01 00:00:00
abstract:OBJECTIVE:To evaluate spontaneous apoptosis in single-cell suspensions of eutopic and ectopic endometrium from women with endometriosis and in eutopic endometrium from fertile controls without endometriosis. DESIGN:Paired specimens of eutopic and ectopic endometrial tissue from patients with endometriosis and eutopic ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(98)00073-9
更新日期:1998-06-01 00:00:00
abstract:OBJECTIVE:To study the expression of FOXO1 and pSer256-FOXO1 parallel to Akt and pSer473-Akt in leiomyoma compared with adjacent myometrium from human uteri. DESIGN:Prospective study. SETTING:University departments. PATIENT(S):Thirty-eight cyclic and 20 menopausal women who underwent hysterectomy for benign indicati...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2009.07.1670
更新日期:2010-09-01 00:00:00
abstract::Discrepancies about a possible relationship between prothrombotic mutations and a decreased uteroplacental blood flow are present in literature. We prospectively evaluated a cohort of pregnant women (n = 41) with bilateral uterine artery notches and found that women with inherited thrombophilia showed a sixfold higher...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2006.01.038
更新日期:2006-09-01 00:00:00
abstract:OBJECTIVE:To describe two cases of in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) with testicular sperm in men with immotile cilia syndromes. DESIGN:Case report. SETTING:A university-based male infertility clinic and assisted reproduction unit. PATIENT(S):Two couples with male factor infert...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(01)01974-4
更新日期:2001-09-01 00:00:00
abstract::Suppression of the pituitary-gonadal axis by the administration of gonadotropin-releasing hormone agonists (GnRH-a) has been used for a variety of endocrinological and gynecological disorders. The suppressive effect of GnRH-a on luteinizing hormone, follicle-stimulating hormone, and sex steroid production is well docu...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)53639-5
更新日期:1990-07-01 00:00:00
abstract::After long-term estradiol deficiency, female rats displayed body mass gain accompanied by an increase in the size of adipocytes, an increase in hyperglycemia, and a decrease in insulinemia. The effects were reversed by daily estradiol treatment. Adiposity was suggested by the increased vascular endothelial growth fact...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2011.01.020
更新日期:2011-03-15 00:00:00
abstract:OBJECTIVE:To study and compare the effects of three sperm separation media, two silica-based (Percoll; Pharmacia Biotech AB, Uppsala, Sweden, and Isolate; Irvine Scientific, Santa Ana, CA) and one non-silica-based (Ixaprep; Medicult, Copenhagen, Denmark), on the recovery of progressive motile sperm, the percentage of s...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(99)00375-1
更新日期:1999-11-01 00:00:00
abstract:OBJECTIVE:To determine Müllerian inhibiting substance (MIS) levels in follicular fluid (FF) and sera of IVF patients. DESIGN:Prospective study. SETTING:Fertility center. PATIENT(S):Sixty-six patients: 20 with tubal factor infertility, 17 with polycystic ovary syndrome (PCOS), and 29 with endometriosis. INTERVENTION...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(97)81417-3
更新日期:1997-05-01 00:00:00
abstract::The transcervical division of uterine septa is usually described as a simple procedure associated with minimal morbidity. Two cases are presented describing late hemorrhage after this procedure. Approaches to avoiding this complication as well as management principles are described. ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)54984-x
更新日期:1992-04-01 00:00:00
abstract:OBJECTIVE:To evaluate which factor, AMH or FSH, was superior in predicting live birth after assisted reproductive technologies (ART) when the tests are discordant, using data from the Society for Assisted Reproductive Technology Clinical Outcomes Reporting System database. DESIGN:Retrospective cohort. SETTING:Clinic-...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2019.03.022
更新日期:2019-07-01 00:00:00
abstract::Dihydrotestosterone released continuously from a subcutaneously implanted Silastic elastomer was more potent than testosterone in reducing circulating gonadotropin and androgen concentrations and in inducing testicular atrophy and infertility despite normal ejaculatory function as judged by the presence of vaginal plu...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)45566-4
更新日期:1981-06-01 00:00:00
abstract::Prior studies have demonstrated that gonadotropin stimulation quality and pregnancy rates are better in in vitro fertilization (IVF) patients with low basal cycle day 3 follicle-stimulating hormone (FSH) levels. The records of 81 patients who had undergone three or more IVF attempts during a 2-year period were studied...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)53707-8
更新日期:1990-08-01 00:00:00
abstract:OBJECTIVE:To evaluate the influence of somatostatin analogue (octreotide) in the function of hypothalamic-pituitary-adrenal (HPA) axis in women with polycystic ovary syndrome (PCOS). SETTING:Women referred to the Department of Obstetrics and Gynecology, Università Cattolica del Sacro Cuore. PATIENT(S):Twelve PCOS wom...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(97)81852-3
更新日期:1997-01-01 00:00:00
abstract:OBJECTIVE:To compare incidence, risk factors, and etiology of women's deaths in fertile, subfertile, and undergoing assisted reproductive technology (ART) in the years after delivery. DESIGN:Retrospective cohort. SETTING:University hospital. PATIENT(S):Women who had delivered in Massachusetts. INTERVENTION(S):This ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2019.10.007
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVE:We evaluated the association between subfertility and low birth weight infants. DESIGN:Women in this analysis participated in a cross-sectional investigation of maternal risk factors for adverse pregnancy outcomes. SETTING:Medical and obstetric history and life style information were obtained from women who...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)54597-x
更新日期:1991-10-01 00:00:00
abstract:OBJECTIVE:To examine the histopathological effects of diabetes on spermatogenesis and to detect the proliferation of germ cells with proliferative cell nuclear antigen (PCNA). DESIGN:Controlled experimental study. SETTING:The animal laboratory of the Experimental Surgery Center of Ege University, Izmir, Turkey. ANIM...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(03)00984-1
更新日期:2003-09-01 00:00:00
abstract::Deoxyribonucleic acid (DNA) flow cytometry of testicular tissue has been demonstrated to be a quantitative means of assessing spermatogenesis. This study evaluates testes aspirates and DNA flow cytometry in the evaluation of the infertile male. Testicular tissue obtained from 12 men who underwent bilateral orchiectomy...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)59358-3
更新日期:1987-08-01 00:00:00
abstract::This case-control study evaluated the effect of hysteroscopically identified endometrial polyps on endometrium by means of HOXA10 and HOXA11, known molecular markers of endometrial receptivity. Uteri with endometrial polyps demonstrated a marked decrease in HOXA10 and HOXA11 messenger RNA levels, which may impair impl...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2010.12.034
更新日期:2011-06-30 00:00:00
abstract:OBJECTIVE:To determine whether the peripheral blood concentration of CD56(+)/CD16(-)/CD3(-) cells, the main natural killer (NK) subpopulation that colonizes the endometrium in the middle and late secretory phase, can be related to fertility or infertility status. DESIGN:A case control study. SETTING:Immunopathology d...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(03)00778-7
更新日期:2003-09-01 00:00:00
abstract:OBJECTIVE:To compare the rate of chromosome abnormalities in embryos obtained from karyotypically normal patients with nonobstructive azoospermia undergoing testicular sperm extraction (TESE) to those from patients undergoing intracytoplasmic sperm injection (ICSI) with ejaculated sperm. DESIGN:Retrospective analysis....
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(02)04407-2
更新日期:2003-01-01 00:00:00