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Avoidance of multiple pregnancies after ovulation induction by supernumerary preovulatory follicular reduction.

Abstract：

OBJECTIVE:To evaluate the effect of supernumerary preovulatory follicular reduction as an approach to avoid multiple pregnancies in ovulation induction or superovulation cycles. DESIGN:Retrospective study. SETTING:Tertiary referral center. PATIENT(S):In 26 cycles, 24 patients underwent ovulation induction or superovulation with either clomiphene citrate or hMG. INTERVENTION(S):Selective follicle aspiration was performed before hCG administration. MAIN OUTCOME MEASURE(S):Clinical pregnancy rate and numbers of multiple pregnancies. RESULT(S):A mean number of 4.5 follicles with a diameter > or =15 mm and a mean number of 4.5 follicles with a diameter < or =14 mm were observed before hCG administration. A mean number of 2.3 follicles with a diameter > or =15 mm and a mean number of 1.8 follicles with a diameter < or =14 mm were aspirated before the hCG administration. Seven singleton pregnancies (26.9% per cycle) ensued from the treatment. CONCLUSION(S):Aspiration of supernumerary follicles after ovulation induction or superovulation seems to be a valid approach to avoid multiple pregnancies without affecting pregnancy rate.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Albano C,Platteau P,Nogueira D,Cortvrindt R,Smitz J,Devroey P

doi

10.1016/s0015-0282(01)02379-2

keywords:

subject

Has Abstract

pub_date

2001-10-01 00:00:00

pages

820-2

issue

4

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(01)02379-2

journal_volume

76

pub_type

杂志文章

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