Abstract：
OBJECTIVE:To evaluate the role of recipient age on the outcome of donor egg cycles. DESIGN:Retrospective cohort study of aggregated national cycles of donor egg therapy that are collected by Society for Assisted Reproductive Technology and the Centers for Disease Control and Prevention. SETTING:Assisted reproductive technology centers in the United States that report their results to the Centers for Disease Control and Prevention by way of the Society for Assisted Reproductive Technology. PATIENT(S):Recipients of embryos (17,339 cycles) derived from donated eggs between 1996 and 1998. INTERVENTION(S):None. MAIN OUTCOME MEASURE(S):Rates of implantation, clinical intrauterine pregnancy, pregnancy loss, and delivery based on the age of the recipient. RESULT(S):Success of donor egg therapy was remarkably constant among recipients aged 25 years through those in their late forties. At higher ages, declining rates of implantation, clinical pregnancy, and delivery were seen, along with small increases of pregnancy loss. During the course of the 3 years studied, fewer embryos were transferred and higher rates of implantation were observed. CONCLUSION(S):The success of donor egg therapy is unaffected by recipient age up to the later 40s, after which they begin to decline. Although recipient age per se is likely to be the major cause of this effect, other factors may contribute to this observation.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Toner JP,Grainger DA,Frazier LMdoi
10.1016/s0015-0282(02)03371-xkeywords:
subject
Has Abstractpub_date
2002-11-01 00:00:00pages
1038-45issue
5eissn
0015-0282issn
1556-5653pii
S001502820203371Xjournal_volume
78pub_type
杂志文章abstract：:A battery-powered, bipolar electrocoagulator has been specifically developed for sealing the cut ends of the divided vas at vasectomy. With a minimum of electric power, the electrocoagulator destroys only the mucosa and one or two muscle cell layers of the vas, which leads to optimal fibrosis of the cut ends. This ins...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1978-06-01 00:00:00
abstract：:Infertile men with azo- or oligospermia of unknown cause were investigated for evidence of testicular autoimmunity. Testicular germinal cell antibodies were found in 14% of the patients, compared with 5% of normal men, and 21% had spermatozoal antibodies, compared with 5% of the normal subjects. One-third had positive...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)41421-4
更新日期：1975-10-01 00:00:00
abstract：OBJECTIVE:To examine the effects of coping and of infertility-specific and nonspecific stress on pregnancy outcomes after IVF treatment. DESIGN:Cross-sectional design controlling for potential confounding variables. Psychosocial measures were assessed on the day of embryo transfer. SETTING:Fertility clinic in Greece....
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2006.02.096
更新日期：2006-09-01 00:00:00
abstract：:Infertile couples who had failed to achieve fertilization of oocytes in previous trials of in vitro fertilization (IVF) were treated by IVF with zona pellucida drilling. Zona drilling entails use of micromanipulation to introduce a gap in the zona pellucida either mechanically or by localized application of a zona sol...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)60010-9
更新日期：1988-07-01 00:00:00
abstract：OBJECTIVE:To summarize the procedures and outcomes of assisted reproductive technology (ART) initiated in the United States in 1997. DESIGN:Data were collected electronically by using Society for Assisted Reproductive Technology Clinical Outcome Reporting System software and were submitted to the American Society for ...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/s0015-0282(00)01559-4
更新日期：2000-10-01 00:00:00
abstract：OBJECTIVE:Potential reparation of sperm DNA fragmentation in the oocyte may disturb any relationship between DNA-damaged sperm and the implantation ability of resulting embryos. To rule out this factor, we analyzed the consequences of sperm DNA fragmentation on IVF-ET outcome in women with healthy ovarian function. DE...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/j.fertnstert.2007.02.022
更新日期：2008-01-01 00:00:00
abstract：OBJECTIVE:To compare the clinical efficacy and safety of the combination of Diane 35 (2 mg of cyproterone acetate, and 35 microg of ethinyl estradiol) plus finasteride (5 mg), and Diane 35 alone in the treatment of hirsutism. DESIGN:Prospective randomized clinical study. SETTING:Outpatients in Erciyes University Medi...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0015-0282(00)01764-7
更新日期：2001-03-01 00:00:00
abstract：OBJECTIVE:To determine plasma adiponectin concentration in women with and without polycystic ovary syndrome (PCOS) and to assess possible correlations of adiponectin to the hormonal and metabolic parameters, including measures of insulin resistance (IR). DESIGN:Case-control study. SETTING:Tertiary-referral university...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2004.11.077
更新日期：2005-06-01 00:00:00
abstract：OBJECTIVE:To compare the performance of the Cook Sydney IVF (SIVF) embryo transfer (ET) catheter and the Edwards-Wallace (EW) ET catheter. DESIGN:Prospective randomized controlled clinical trial with an intention-to-treat analysis. SETTING:Two-center study. PATIENT(S):Four hundred consecutive women <40 years undergo...
journal_title：Fertility and sterility
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.fertnstert.2007.06.085
更新日期：2008-09-01 00:00:00
abstract：OBJECTIVE:To investigate whether BRCA carriers with and without malignancy have decreased ovarian reserve at baseline compared with BRCA noncarriers. DESIGN:Retrospective cohort study. SETTING:Academic medical center. PATIENT(S):Seven-hundred and ninety-five oocyte cryopreservation patients, comprising BRCA carriers...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2018.10.014
更新日期：2019-02-01 00:00:00
abstract：:To evaluate the effectiveness of intravenous metoclopramide, alone or in combination with luteinizing hormone-releasing hormone (LH-RH), in distinguishing between constitutional delay of puberty and hypogonadotropic hypogonadism, 12 patients with constitutional delay of puberty and 10 patients with hypogonadotropic hy...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)60788-4
更新日期：1989-07-01 00:00:00
abstract：OBJECTIVE:To investigate the effect of the anti-P Org 31710 on human blastocyst attachment to cultured endometrial epithelial cells. DESIGN:Experimental in vitro study. SETTING:University hospital. PATIENT(S):Eleven fertile endometrial donors. INTERVENTION(S):Timed endometrial biopsy for cell cultures. MAIN OUTCOM...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2004.08.040
更新日期：2005-04-01 00:00:00
abstract：:The antiprogesterone compound RU 486 (17 beta-hydroxy-11 beta-[4-dimethylaminophenyl]-17 alpha-[ 1-propynyl]estra-4,9-dien-3-one; Roussel-Uclaf, Paris, France) was used to induce menstruation in a randomized controlled trial. Castrated adult female cynomolgus monkeys (n = 17) received sequential subcutaneous Silastic ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)47246-8
更新日期：1983-08-01 00:00:00
abstract：OBJECTIVE:To determine if the solubilized human zona pellucida (ZP)-induced acrosome reaction is mediated by protein kinases. DESIGN:Capacitated spermatozoa were incubated with inhibitors of cyclic adenosine 3':5'-monophosphate (cAMP)-dependent kinase (KT5720), Ca(2+)- and phospholipid-dependent kinase (Calphostin C),...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1994-03-01 00:00:00
abstract：OBJECTIVE:To evaluate the efficacy of a dry versus humidified incubator on human embryo development ex vivo. DESIGN:Prospective, double-blind, randomized, controlled trial. SETTING:Private fertility centers. PATIENT(S):A total of 297 women undergoing in vitro fertilization randomized into two groups. INTERVENTION(S...
journal_title：Fertility and sterility
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.fertnstert.2017.05.036
更新日期：2017-08-01 00:00:00
abstract：OBJECTIVE:To demonstrate the pattern(s) of spermatogonial proliferation in different spermatogenic disorders. DESIGN:Retrospective case-control study. Teaching hospital. PATIENT(S):Azoospermic men who underwent testicular biopsy for sperm recovery and preparation for intracytoplasmic sperm injection. INTERVENTION(S)...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(03)02161-7
更新日期：2003-11-01 00:00:00
abstract：OBJECTIVE:To report a case of laparoscopic treatment of a heterotopic primary abdominal pregnancy after IVF with preservation of the concurrent intrauterine pregnancy. DESIGN:Case report. SETTING:University-based IVF program. PATIENT(S):A woman with a heterotopic abdominal pregnancy after IVF-ET. INTERVENTION(S):Pi...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(98)00104-6
更新日期：1998-07-01 00:00:00
abstract：:Well-designed and -conducted clinical trials are needed to further advance the field for reproductive medicine. However, current reporting of outcomes of trials is ambiguous and disparate. In this review it is offered that the preferred outcome for clinical trials in reproductive medicine should be live birth. Multipl...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2014.03.026
更新日期：2014-05-01 00:00:00
abstract：OBJECTIVE:To describe the treatments of a patient using the laparoscopic Davydov's method for Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome and ureteral reimplantation for hydronephrosis and hydroureter. DESIGN:Surgical video article. A consent form from the patient was obtained as appropriate; the nature of the stud...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2020.08.1433
更新日期：2020-10-14 00:00:00
abstract：OBJECTIVE:To investigate whether antiphospholipid and related autoantibodies are associated with IVF implantation failure as well as with recurrent spontaneous miscarriage. DESIGN:Prevalence study. SETTING:University teaching hospital and associated IVF unit. PATIENT(S):Patients with at least three consecutive first...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/s0015-0282(98)00312-4
更新日期：1998-11-01 00:00:00
abstract：OBJECTIVE:To determine if adult human endometrium possesses an intact müllerian-inhibiting substance (MIS) signal transduction system and, if so, whether MIS can modulate endometrial cell viability. DESIGN:Adult human endometrial tissue was subjected to reverse transcription polymerase chain reaction (RT-PCR) analysis...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.01.028
更新日期：2009-04-01 00:00:00
abstract：OBJECTIVE:To estimate the prevalence and the characteristics of intrauterine adhesions after cold loop resectoscopic myomectomy. DESIGN:Retrospective study. SETTING:Endoscopic gynecologic center. PATIENT(S):688 women with one or more G1-G2 myomas. INTERVENTION(S):Cold loop resectoscopic myomectomy and diagnostic hy...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2013.09.032
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVE:To determine DNA fragmentation and several molecules associated with apoptosis or proliferation in ovaries of patients with diminished ovarian reserve. DESIGN:Cross-sectional analysis. SETTING:Tertiary institutional hospital. PATIENT(S):Patients with benign uterine pathology who had undergone a hysterectom...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2005.12.075
更新日期：2006-07-01 00:00:00
abstract：OBJECTIVE:To demonstrate laparoscopic surgery for a patient with unicornuate uterus and a large hematometra in the noncommunicating uterine horn. DESIGN:Narrated video featuring the diagnostic tests and surgical management. SETTING:Academic tertiary hospital. PATIENT(S):A 13-year-old woman, gravida 0 with menarche a...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2020.05.042
更新日期：2020-11-01 00:00:00
abstract：:Luteal phase defect (LPD) accounts for a significant proportion of reproductive disorders, however its etiology is still debated. A prospective study was performed on 37 ovulatory women to determine whether LPD can occur in cycles characterized by completely normal folliculogenesis. Criteria for normal folliculogenesi...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)53152-5
更新日期：1989-12-01 00:00:00
abstract：:The Hammen semen quality classification system is a fertility index with six qualities based on sperm count, assessment of sperm motility, number of immotile spermatozoa, number of abnormal sperm heads, and sperm viability. It was developed by Hammen during the 1940s. In the present study, the fertility of 1077 men cl...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)45624-4
更新日期：1981-07-01 00:00:00
abstract：:The effectiveness of antiestrogens and progestins in the inhibition of capacitation in the rabbit uterus and oviduct was studied. The agents tested were 8 mg/day nafoxidine HCL (NHCL), 4 mg/day fluoxymesterone (FM), 4 and 20 mg/day clomiphene citrate (CC), 8 mg/day testosterone (T), 8 mg/day dydrogesterone (D) 4 and ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1972-03-01 00:00:00
abstract：:Levels of specific antibodies against model antigens, immunoglobulins G and A and also albumin, in oviductal fluid were studied in the rhesus monkey during the periovulatory period. Animals were systemically or intravaginally immunized against T4 coliphages. Attempts to induce ovulation were made with human menopausal...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1983-03-01 00:00:00
abstract：OBJECTIVE:To determine whether the oncofetal protein IMP3 is detectable in endometriomas with or without histological atypia and whether IMP3 staining can be used as a triage tool to identify foci of atypical endometriosis in doubtful cases. DESIGN:Retrospective study. SETTING:Academic department and referral center ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2013.02.002
更新日期：2013-06-01 00:00:00
abstract：:Oocytes with three or more pronuclei and one or two polar bodies arising after intracytoplasmic sperm injection were analyzed cytogenetically, and the data were used to develop a general model explaining the possible origin of the abnormal pronuclear stages. The mechanisms, either separately or in variable combination...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2010.03.075
更新日期：2010-11-01 00:00:00
