A preliminary concept, deduced from cytogenetic analyses, for explaining different types of multipronuclear oocytes obtained after intracytoplasmic sperm injection.

Abstract:

:Oocytes with three or more pronuclei and one or two polar bodies arising after intracytoplasmic sperm injection were analyzed cytogenetically, and the data were used to develop a general model explaining the possible origin of the abnormal pronuclear stages. The mechanisms, either separately or in variable combinations, that induce the appearance of additional pronuclei are: 1) nonextrusion of the second polar body; 2) incomplete chromatid segregation into the extruded second polar body; and 3) dispersal of the oocyte chromatids in the presence of the second polar body formation.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Rosenbusch BE

doi

10.1016/j.fertnstert.2010.03.075

subject

Has Abstract

pub_date

2010-11-01 00:00:00

pages

2479-81

issue

6

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(10)00536-4

journal_volume

94

pub_type

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