Increased expression of endothelin-1 and its receptors in varicocele: an immunohistochemical study.

Abstract:

:We hypothesized that diminished endothelin 1 (ET-1) expression at the spermatic vein wall level might be responsible for the development of varicocele. However, immunohistochemical evaluation of spermatic and control vein samples from 55 patients with varicocele showed overexpression of ET-1 and its receptors ETA and ETB in varicose veins.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Gyftopoulos K,Chondrogianni C,Papadaki H

doi

10.1016/j.fertnstert.2011.04.062

subject

Has Abstract

pub_date

2011-06-30 00:00:00

pages

2554-6.e1-2

issue

8

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(11)00675-3

journal_volume

95

pub_type

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