The bactericidal activity of sera of healthy neonates and of newborns with hyperbilirubinaemia to Escherichia coli.

Abstract:

:Cord and newborn sera were found to possess a significantly decreased in vitro bactericidal activity to Escherichia coli as compared to sera of adult individuals. Hyperbilirubinaemia in neonates suffering from both Rh and ABO incompatibility results in a further significant impairment of the bactericidal activity of their sera in comparison with healthy newborn infants. Exchange transfusion improved considerably the serum bactericidal activity. The possible mechanism of toxic action of unconjugated bilirubin on cells of the immune system is discussed.

journal_title

Folia microbiologica

authors

Miler I,Vondrácek J,Hromádková L

doi

10.1007/BF02927298

subject

Has Abstract

pub_date

1979-01-01 00:00:00

pages

143-52

issue

2

eissn

0015-5632

issn

1874-9356

journal_volume

24

pub_type

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