Abstract:
:Thirty-four thiosemicarbazones and S-alkyl thiosemicarbazones, and some of their Zn(II) and Pd(II) complexes were obtained and purified to investigate antimicrobial activity. MIC values of the compounds were determined by the disc diffusion method against Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, Salmonella typhi, Shigella flexneri, Staphylococcus aureus, S. epidermidis, and Candida albicans. The thiosemicarbazones show antibacterial and antifungal effects in free ligand and metal-complex form. Picolinaldehyde-S-methyl- and -S-benzylthiosemicarbazones did not affect the tested microorganisms but their Zn(II) complexes showed selective activity. The antimicrobial activity is relatively high in Me2SO, but the antimicrobial potential is changed in a certain range with Me2SO, HCONMe2, EtOH and CHCl3.
journal_name
Folia Microbiol (Praha)journal_title
Folia microbiologicaauthors
Kizilcikli I,Kurt YD,Akkurt B,Genel AY,Birteksöz S,Otük G,Ulküseven Bdoi
10.1007/BF02932132subject
Has Abstractpub_date
2007-01-01 00:00:00pages
15-25issue
1eissn
0015-5632issn
1874-9356journal_volume
52pub_type
杂志文章abstract::Mice (strains Balb/c and A/J) received an intravenous infusion of bilirubin for a 1 d period. The infusion was delivered at various phases of the primary reaction; the degree of the immune response was expressed as the number of antibody-forming cells against sheep erythrocytes. Bilirubin infusion during both the indu...
journal_title:Folia microbiologica
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journal_title:Folia microbiologica
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journal_title:Folia microbiologica
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journal_title:Folia microbiologica
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doi:10.1007/BF02931464
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journal_title:Folia microbiologica
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journal_title:Folia microbiologica
pub_type: 杂志文章,评审
doi:10.1007/BF02818976
更新日期:1997-01-01 00:00:00
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journal_title:Folia microbiologica
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doi:10.1007/BF02876690
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journal_title:Folia microbiologica
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journal_title:Folia microbiologica
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更新日期:2009-11-01 00:00:00
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journal_title:Folia microbiologica
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doi:10.1007/BF02883235
更新日期:1987-01-01 00:00:00
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更新日期:2007-01-01 00:00:00
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journal_title:Folia microbiologica
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更新日期:2015-11-01 00:00:00
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更新日期:1991-01-01 00:00:00
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journal_title:Folia microbiologica
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更新日期:2010-11-01 00:00:00
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journal_title:Folia microbiologica
pub_type: 杂志文章
doi:10.1007/BF02818557
更新日期:1999-01-01 00:00:00
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