Formation of extracellular neutral proteinase and the stringent response in Bacillus subtilis.

Abstract:

:The kinetics of extracellular neutral proteinase synthesis by an isogenic stringent (IS58) and a relaxed (IS56) strain of B. subtilis were compared. The specific enzyme formation rate by the stringent strain was higher than that of the relaxed one. Norvaline addition (1 mg/mL) induced the formation of pppGpp and ppGpp, respectively, as well as the appearance of extracellular neutral proteinase activities in cultures of the stringent strain IS58 and a strain with high proteinase production (ZF-178) only. These correlations support the suggestion that (p)ppGpp are involved in the regulation processes responsible for production of extracellular neutral proteinases by B. subtilis.

journal_title

Folia microbiologica

authors

Riedel K,Schroeter A,Liebs P,Graba JP,Hecker M,Schrapel D

doi

10.1007/BF02883234

subject

Has Abstract

pub_date

1987-01-01 00:00:00

pages

96-100

issue

2

eissn

0015-5632

issn

1874-9356

journal_volume

32

pub_type

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