Abstract：
:When investigating the possible antitrichomodal effect of 41 phenylsazones, nitro- and dinitro-phenylhydrazones a significant inhibitory effect on multiplication of Trichomonas foetus could be detected in 14 derivatives; eight derivatives were ineffective, other derivatives exhibited only a slight effect. The inhibitory effect of most compounds increased after acetylation. Toxicity of seven effective compounds was determined in vivo. Mutagenicity of these compounds was followed with microorganisms and their cytotoxicity with tumor EAC cells. Two of the effective compounds exhibited also a significant mutagenic effect, three of eight compounds had a pronounced cytotoxic effect, three of eight compounds had a pronounced cytotoxic effect in vitro on the EAC cells, in which they inhibited mainly the incorporation of adenine.
journal_name
Folia Microbiol (Praha)journal_title
Folia microbiologicaauthors
Fuska J,Fusková A,Kettner M,Frank V,Linek Kdoi
10.1007/BF02883838subject
Has Abstractpub_date
1982-01-01 00:00:00pages
49-54issue
1eissn
0015-5632issn
1874-9356journal_volume
27pub_type
杂志文章abstract：:Brefeldin A has been recently characterized to act as an inhibitor of intracellular protein export with profound effects on the structure and function of the Golgi apparatus in animal cells. Manifold activities of the antibiotic (under different names) published in the 1960's and 1970's are reviewed: effects on fungal...
journal_title：Folia microbiologica
pub_type： 杂志文章,评审
doi：10.1007/BF02814572
更新日期：1992-01-01 00:00:00
abstract：:This study was undertaken to develop a new Gram-staining machine controlled by a micro-controller and to investigate the quality of slides that were stained in the machine. The machine was designed and produced by the authors. It uses standard 220 V AC. Staining, washing, and drying periods are controlled by a timer b...
journal_title：Folia microbiologica
pub_type： 杂志文章
doi：10.1007/BF02818557
更新日期：1999-01-01 00:00:00
abstract：:The validity of the principle of homeoviscous adaptation for Bacillus subtilis was tested by comparing fluorescence anisotropy (1,6-diphenyl-1,3,5-hexatriene) and electron-spin resonance (16-doxylstearate) measurements carried out in isolated plasma membranes and in phospholipid fractions. The physical measurements we...
journal_title：Folia microbiologica
pub_type： 杂志文章
doi：10.1007/BF02925901
更新日期：1988-01-01 00:00:00
abstract：:Escherichia coli strain HB101 harboring an expression plasmid bearing calf prochymosin gene under the control of the tac promoter was grown in the presence of IPTG with or without novobiocin at 28 and 40 degrees C, respectively. The differential rates of synthesis of prochymosin inclusions, and, for comparison, of bet...
journal_title：Folia microbiologica
pub_type： 杂志文章
doi：10.1007/BF02815545
更新日期：1998-01-01 00:00:00
abstract：:Raoultella spp. representatives are Gram-negative capsulated, nonmotile rods. These bacteria are found in the natural environment: plants, water, soil and insects. R. ornithinolytica is one of the three species of Raoultella. R. ornithinolytica is the only species within the genus which has the ability to produce orni...
journal_title：Folia microbiologica
pub_type： 杂志文章
doi：10.1007/s12223-015-0390-2
更新日期：2015-11-01 00:00:00
abstract：:Phosphatidylcholine is one of the most frequent phospholipid components of the inner mitochondrial membrane of Neurospora crassa. Quantitative analysis of phosphlipids of the wild strain of Neurospora crassa and of its two cho mutants showed that these strains did not significantly differ in the content of phosphatidy...
journal_title：Folia microbiologica
pub_type： 杂志文章
doi：10.1007/BF02879763
更新日期：1982-01-01 00:00:00
abstract：:Due to the nature of Vibrio vulnificus infections (i.e., gastroenteritis and septicemia), only very few studies of a biofilm-associated form in this pathogen's life cycle have been conducted. We proposed that biofilm production by clinical strains of V. vulnificus would be higher than by environmental strains. Biofilm...
journal_title：Folia microbiologica
pub_type： 杂志文章
doi：10.1007/s12223-019-00761-9
更新日期：2020-06-01 00:00:00
abstract：:The efficacy of the agents was evaluated on the basis of minimum inhibitory concentration (MIC) and time-kill curve analysis in Pseudomonas aeruginosa, Staphylococcus aureus, Acinetobacter baumannii, Mycobacterium smegmatis, and Citrobacter braakii; MIC was found to be 0.5, 4.0, 0.015625, 0.0078125, and 0.0625 mg/L in...
journal_title：Folia microbiologica
pub_type： 杂志文章
doi：10.1007/s12223-009-0054-1
更新日期：2009-09-01 00:00:00
abstract：:The induction of tryptophanase was not affected by rifampicin in the rifampicin-resistant mutant of Vibrio el tor while the antibiotic inhibited the induction of tryptophanase in the normal strain at level of ribonucleic acid and protein synthesis. ...
journal_title：Folia microbiologica
pub_type： 杂志文章
doi：10.1007/BF02877677
更新日期：1977-01-01 00:00:00
abstract：:The postantibiotic effect (PAE) and the postantibiotic sub-MIC effect (PASME) of ciprofloxacin, pefloxacin and amikacin were studied for Salmonella typhimurium and S. enteritidis strains. PAE was induced by 2 x and 4 x MIC of antibiotics studied for 0.5 h. After PAE and PASME their effect on prophage induction of a ly...
journal_title：Folia microbiologica
pub_type： 杂志文章
doi：10.1007/BF02816944
更新日期：1997-01-01 00:00:00
abstract：:Aliphatic 1,2-alkanolamines inhibited beta-glucanase from Candida utilis. The highest inhibitory effect was observed with 1-dodecylamino-3-chloro-2-propanol (Ki = 1.0 mumol/L) and it was much higher than that of D-glucono-delta-lactone. Simple 1,2-alkanolamines, like 2-aminoethanol or 2-methylaminoethanol, did not exh...
journal_title：Folia microbiologica
pub_type： 杂志文章
doi：10.1007/BF02898763
更新日期：1993-01-01 00:00:00
abstract：:Mycobacterium microti-infected mouse peritoneal macrophages produced high amounts of prostaglandin E2 (PGE2) and nitric oxide (NO) when activated with interferon-gamma (IFN-gamma). In order to understand the relation between PGE2 and NO production and the expression of interleukin-12 (IL-12), interleukin-10 (IL-10) an...
journal_title：Folia microbiologica
pub_type： 杂志文章
doi：10.1007/BF02818541
更新日期：2001-01-01 00:00:00
abstract：:Small plasmid pKST23 was isolated from sheep ruminal Escherichia coli population. Plasmid sequence was determined to be 2,779 bp in length and was found to have an overall 42 % of GC pairs. However, its sequence can be divided into two regions based on genetic composition and the GC content. It was found that the high...
journal_title：Folia microbiologica
pub_type： 杂志文章
doi：10.1007/s12223-012-0124-7
更新日期：2012-07-01 00:00:00
abstract：:Treatment of Helicobacter pylori cells with several chaotropic agents resulted in different degrees of inhibition in the binding of the bacteria to hemin and Congo-red dye. Polyanions also yielded a >50% inhibitory effect. Furthermore, hydrophobic interaction chromatography was used to determine the relative surface h...
journal_title：Folia microbiologica
pub_type： 杂志文章
doi：10.1007/s12223-011-0043-z
更新日期：2011-05-01 00:00:00
abstract：:The aim of this study was to determine the prevalence of Listeria sp. and Listeria monocytogenes in soil samples with reference to type of fertilizers (natural and artificial) and distance from places intensively exploited by men, as well as to determine the relationship between the presence of L. monocytogenes in the...
journal_title：Folia microbiologica
pub_type： 杂志文章
doi：10.1007/s12223-013-0260-8
更新日期：2014-01-01 00:00:00
abstract：:Superoxide dismutases, both cytosolic Cu, Zn-SOD encoded by SOD1 and mitochondrial Mn-SOD encoded by SOD2, serve Saccharomyces cerevisiae cells for defense against the superoxide radical but the phenotypes of sod1A and sod2delta mutant strains are different. Compared with the parent strain and the sod1delta mutant, th...
journal_title：Folia microbiologica
pub_type： 杂志文章
doi：10.1007/BF02932150
更新日期：2007-01-01 00:00:00
abstract：:Propionate at concentrations up to 0.05% decreased at 25 degrees C the growth and sporulation of Penicillium aurantiogriseum. The standard size of conidiogenous structures (metulae, phialids) and conidia was diminished. The effect was more pronounced at a higher temperature (30 degrees C). Inhibition of ochratoxin pro...
journal_title：Folia microbiologica
pub_type： 杂志文章
doi：10.1007/BF02814202
更新日期：1995-01-01 00:00:00
abstract：:The effect of dental plaque bacteria on LFA-1 beta expression on peripheral blood leukocytes was studied in 20 patients with early-onset periodontitis and in 10 healthy controls. Stimulation of PMN with selected dental plaque bacteria which play a role in the pathogeny of periodontitis significantly increased the expr...
journal_title：Folia microbiologica
pub_type： 杂志文章
doi：10.1007/BF02815697
更新日期：1996-01-01 00:00:00
abstract：:A method is presented for the successful decontamination of sparingly soluble pteridine derivatives by microwave irradiation. The method is nondestructive, rapid and effective in eliminating contamination. ...
journal_title：Folia microbiologica
pub_type： 杂志文章
doi：10.1007/BF02814514
更新日期：1991-01-01 00:00:00
abstract：:A hexokinase preparation was obtained from a Saccharomyces cerevisiae mutant strain deficient in glucosephosphate isomerase (GPI) and mannosephosphate isomerase (MPI) by precipitation with ammonium sulfate. The supernatant fraction corresponding to 40-60 % saturation showed the lowest content in GPI and MPI activity. ...
journal_title：Folia microbiologica
pub_type： 杂志文章
doi：10.1007/BF02927364
更新日期：1981-01-01 00:00:00
abstract：:Streptomyces aureofaciens glucosidizes 1,2,4-trihydroxy-9,10-anthraquinone (purpurin) added to the cultivation medium to yield the corresponding 2-beta-D-glucoside. The identity of the glucoside was demonstrated by comparing its physico-chemical properties with data of an authentic sample prepared synthetically. A fur...
journal_title：Folia microbiologica
pub_type： 杂志文章
doi：10.1007/BF02873156
更新日期：1984-01-01 00:00:00
abstract：:beta-Glucosidase from the fungus Thermoascus aurantiacus grown on semi-solid fermentation medium (using ground corncob as substrate) was partially purified in 5 steps--ultrafiltration, ethanol precipitation, gel filtration and 2 anion exchange chromatography runs, and characterized. After the first anion exchange chro...
journal_title：Folia microbiologica
pub_type： 杂志文章
doi：10.1007/BF02818672
更新日期：2002-01-01 00:00:00
abstract：:A naturally deficient thiamine and methionine requiring strain of Bacillus coagulans (Ms 5) accumulates lysine in medium only when exogenous pyridoxine (optimal concentration, 0.1 mu g/ml) are supplied. Threonine exerts an inhibitory effect at higher concentrations but pyridoxine does not. ...
journal_title：Folia microbiologica
pub_type： 杂志文章
doi：10.1007/BF02877085
更新日期：1975-01-01 00:00:00
abstract：:Using fluorescein-labelled antibodies against gamma, mu and alpha chains, Ig-containing cells in palatine tonsils were studied in 120 patients. The aim of this study was to determine the most frequently repeated typical findings as regards the numbers and localisation of these cells in tonsils and to confront the data...
journal_title：Folia microbiologica
pub_type： 杂志文章
doi：10.1007/BF02927432
更新日期：1981-01-01 00:00:00
abstract：:The effect of paraquat on the activities of antioxidant defense and detoxifying enzymes of the white-rot fungus Funalia trogii was determined. Paraquat increased the activities of glutathione reductase (GR), glutathione transferase (GT) and superoxide dismutase at 1 mmol/L, while at 0.1 mmol/L it did not affect the ac...
journal_title：Folia microbiologica
pub_type： 杂志文章
doi：10.1007/BF02818700
更新日期：2002-01-01 00:00:00
abstract：:We present the results of analysis of membrane phosphoproteomes from individual morphological stages of Streptomyces coelicolor that reflect developmentally dependent heterogeneity and phosphorylation of intrinsic and externally added purified Strepomyces aureofaciens EF-Tu. Fast growing nonpathogenic Mycobacterium sm...
journal_title：Folia microbiologica
pub_type： 杂志文章
doi：10.1007/s12223-010-0029-2
更新日期：2010-05-01 00:00:00
abstract：:The microflora of the chernozem soil mineralized 62% of the lactose retained on a column consisting of three 10-g layers of the soil at a daily flow of 48 mg of the sugar. Only 45% of the sugar was mineralized when the daily flow was 136 mg. The highest value of the beta-galactosidase activity in the system of heteroc...
journal_title：Folia microbiologica
pub_type： 杂志文章
doi：10.1007/BF02927259
更新日期：1981-01-01 00:00:00
abstract：:A total of 152 lactic acid bacteria (LAB) were isolated from pickles produced in the Ankara-Çubuk region. These isolates were clustered into eight groups on the basis of their phenotypic characteristics including cell morphology, CO2 production from glucose, growth at 10 and 45 °C, growth in 6.5 % NaCl, and growth at ...
journal_title：Folia microbiologica
pub_type： 杂志文章
doi：10.1007/s12223-014-0363-x
更新日期：2015-05-01 00:00:00
abstract：:As phospholipases of mycoplasma species may play a role in the pathogenesis of respiratory tract and urogenital tract diseases Mycoplasma mycoides and Acholeplasma laidlawii were examined as to the production of phospholipase A2 (PLA) and attempts were made to purify and characterize it. Both species produced PLA. The...
journal_title：Folia microbiologica
pub_type： 杂志文章
doi：10.1007/BF02814471
更新日期：1989-01-01 00:00:00
abstract：:Fifty Escherichia coli strains isolated from stool samples of 51 healthy children, 143 strains isolated from stool samples of 327 children with diarrhea and 24 strains isolated from stool samples of 21 children with suspected hemolytic uremic syndrome were examined for the presence of Shiga toxin-producing E. coli vir...
journal_title：Folia microbiologica
pub_type： 杂志文章
doi：10.1007/BF02817680
更新日期：2002-01-01 00:00:00
