Mitogenic activity of cementum components to gingival fibroblasts.

abstract：:Hydrogen sulfide (H2S) and methyl mercaptan (CH3SH) are the volatile sulfur compounds (VSC) that were investigated for a possible role in the etiology of periodontal disease. The results show that the permeability of porcine non-keratinized sublingual mucosa is increased by up to 75% or 103% following exposure to H2S ...

journal_title：Journal of dental research

authors： Ng W,Tonzetich J

更新日期：1984-07-01 00:00:00

abstract：:Components of resin materials may damage DNA, leading to genetic alterations in mammalian cells. Here, monomers were analyzed for the induction of chromosomal aberrations indicated by micronuclei induced in V79 cells. A dose-related increase in the numbers of micronuclei was observed with triethyleneglycol dimethacryl...

journal_title：Journal of dental research

authors： Schweikl H,Schmalz G,Spruss T

更新日期：2001-07-01 00:00:00

abstract：:Since Thewlis found the "two fiber axes" patterns on x-ray diffractograms of human enamel in 1934, many investigators have studied this problem. However, a definite answer has not yet been obtained. The present detailed x-ray diffraction study showed that the "two fiber axes" patterns in human enamel were caused by re...

journal_title：Journal of dental research

authors： Hirota F

更新日期：1986-07-01 00:00:00

abstract：:The pellicle serves as a multifunctional protective layer, providing, e.g., lubrication and remineralization and also acting as a diffusion barrier. In addition, since the formation of the pellicle precedes the adhesion of micro-organisms, it is also important as a conditioning film. We present a novel approach to stu...

journal_title：Journal of dental research

authors： Sotres J,Pettersson T,Lindh L,Arnebrant T

更新日期：2012-10-01 00:00:00

abstract：:The ability of human oral bacteria to inhibit Streptococcus mutans was studied under a variety of in vitro conditions using an agar overlay assay. Extensive inherent variability in microbial antagonism by certain organisms was demonstrated. Antagonistic activity was also significantly influenced by changes in the assa...

journal_title：Journal of dental research

authors： Deyloff JL,Sanders CC

更新日期：1980-11-01 00:00:00

abstract：:Early childhood caries (ECC) is a chronic disease affecting the oral health of children globally. This disease is multifactorial, but a primary factor is cariogenic microorganisms such as Streptococcus mutans. Biosynthetic gene clusters (BGCs) encode small molecules with diverse biological activities that influence th...

journal_title：Journal of dental research

authors： Momeni SS,Beno SM,Baker JL,Edlund A,Ghazal T,Childers NK,Wu H

更新日期：2020-07-01 00:00:00

abstract：:Investigators have used chemotherapeutic agents topically for plaque control without knowing the drug concentration necessary to inhibit the growth of odontopathic microorganisms. S mutans, S sanguis, A viscosus and A naeslundii are important components of the plaque flora. The minimal inhibitory concentrations (MIC) ...

journal_title：Journal of dental research

authors： Newbrun E,Felton RA,Bulkacz J

更新日期：1976-07-01 00:00:00

abstract：:Because bone reconstruction in irradiated sites is less than ideal, we applied a regenerative gene therapy method in which a cell-signaling virus was localized to biomaterial scaffolds to regenerate wounds compromised by radiation therapy. Critical-sized defects were created in rat calvariae previously treated with ra...

journal_title：Journal of dental research

authors： Hu WW,Ward BB,Wang Z,Krebsbach PH

更新日期：2010-01-01 00:00:00

abstract：:Genetic influences are important in the determination of mandibular morphology, and growth hormone receptor (GHR) is believed to have an important influence on the growth of craniofacial bone. In this study, we used quantitative trait locus methods to evaluate the relationship between craniofacial morphology and singl...

journal_title：Journal of dental research

authors： Zhou J,Lu Y,Gao XH,Chen YC,Lu JJ,Bai YX,Shen Y,Wang BK

更新日期：2005-11-01 00:00:00

abstract：:In order for the role of parotid amylase in starch digestion in the gastro-intestinal tracts of diabetic rats to be clarified, this study investigated the effect of parotid-duct ligation on both amylase secretion from the parotid glands and pancreas into the gastro-intestinal tract and on starch digestion in the gastr...

journal_title：Journal of dental research

authors： Kurahashi M,Inomata K

更新日期：1989-09-01 00:00:00

abstract：:We report a clinical study that examines whether HIV infection affects Streptococcus mutans colonization in the oral cavity. Whole stimulated saliva samples were collected from 46 HIV-seropositive individuals and 69 HIV-seronegative control individuals. The level of S. mutans colonization was determined by conventiona...

journal_title：Journal of dental research

authors： Liu G,Saxena D,Chen Z,Norman RG,Phelan JA,Laverty M,Fisch GS,Corby PM,Abrams W,Malamud D,Li Y

更新日期：2012-09-01 00:00:00

abstract：:Selected strains of oral Streptococcus and Actinomyces have been tested for their ability to grow in the presence of mercury. Strains were tested for growth on a semi-defined medium with low mercury-binding characteristics. Sensitivities were initially measured on agar plates, and subsequently, selected strains were g...

journal_title：Journal of dental research

authors： Lyttle HA,Bowden GH

更新日期：1993-09-01 00:00:00

abstract：:In a standard periodontal treatment strategy with consecutive root planings (per quadrant at a one- to two-week interval), re-infection of a disinfected area might occur before completion of the treatment. This study examines, both clinically and microbiologically, whether a full-mouth disinfection within 24 hours sig...

journal_title：Journal of dental research

authors： Quirynen M,Bollen CM,Vandekerckhove BN,Dekeyser C,Papaioannou W,Eyssen H

更新日期：1995-08-01 00:00:00

abstract：:Lysozyme concentration was quantitated immunochemically in parotid and submandibular-sublingual saliva of 46 caries-resistant and 17 caries-susceptible adults. There was essentially no difference between the two groups. The concentration of lysozyme was three times higher in the submandibular-sublingual than in the pa...

journal_title：Journal of dental research

authors： Stuchell RN,Mandel ID

更新日期：1983-05-01 00:00:00

abstract：:Dentin sialoprotein (DSP) and dentin phosphoprotein (DPP) are expressed as a single mRNA transcript coding for a large precursor protein termed dentin sialophosphoprotein (DSPP). DSP, DPP, and DSPP have been considered to be tooth-specific. To test for the expression of the dspp gene in bone, we performed Western immu...

journal_title：Journal of dental research

authors： Qin C,Brunn JC,Cadena E,Ridall A,Tsujigiwa H,Nagatsuka H,Nagai N,Butler WT

更新日期：2002-06-01 00:00:00

abstract：:Synovial hyperplasia is a feature of degenerative temporomandibular joint (TMJ) disease. However, the mechanism by which hyperplasia progresses in the TMJ is unknown. Based on the hypothesis that the oxidative stress generated by mechanical loading causes degenerative changes in the TMJ synovium, we investigated the g...

journal_title：Journal of dental research

authors： Yamaza T,Masuda KF,Atsuta I,Nishijima K,Kido MA,Tanaka T

更新日期：2004-08-01 00:00:00

abstract：:Radiation therapy for head and neck cancer results in severe secondary side-effects in salivary glands. We previously demonstrated that the administration of IGF1 preserves or restores salivary gland function following radiation. Based on these findings, we propose to study the effect of IGF1 on human head and neck ca...

journal_title：Journal of dental research

authors： Victory K,Burd R,Fribley A,Sittadjody S,Arnett D,Klein RR,Limesand KH

更新日期：2011-03-01 00:00:00

abstract：:Cementum is known to be growth-hormone (GH)-responsive, but to what extent is unclear. This study examines the effects of extremes of GH status on cementogenesis in three lines of genetically modified mice; GH excess (giant), GH antagonist excess (dwarf), and GH receptor-deleted (GHR-KO) (dwarf). Age-matched mandibula...

journal_title：Journal of dental research

authors： Smid JR,Rowland JE,Young WG,Daley TJ,Coschigano KT,Kopchick JJ,Waters MJ

更新日期：2004-01-01 00:00:00

abstract：:Moderate elevation of serum C-reactive protein (CRP) is a risk factor for cardiovascular disease among apparently healthy individuals, although factors that create this inflammatory response in the absence of systemic illness have not been clarified. This study aimed to: (1) evaluate associations among periodontal dis...

journal_title：Journal of dental research

authors： Slade GD,Offenbacher S,Beck JD,Heiss G,Pankow JS

更新日期：2000-01-01 00:00:00

abstract：:Dental epithelial progenitor cells differentiate into various cell types during development of tooth germs. To study this mechanism, we produced immortalized dental epithelial progenitor cells derived from the cervical-loop epithelium of a rat lower incisor. The expression patterns of cytokeratin 14, nerve growth fact...

journal_title：Journal of dental research

authors： Kawano S,Saito M,Handa K,Morotomi T,Toyono T,Seta Y,Nakamura N,Uchida T,Toyoshima K,Ohishi M,Harada H

更新日期：2004-02-01 00:00:00

abstract：:The acquired dental pellicle helps prevent erosion, but the protection level is unknown. This in situ study tested whether a two-hour pellicle protects against different erosive challenges by orange juice. Subjects wore palatal appliances loaded with either enamel or dentin specimens. Pellicle was allowed to form, or ...

journal_title：Journal of dental research

authors： Hara AT,Ando M,González-Cabezas C,Cury JA,Serra MC,Zero DT

更新日期：2006-07-01 00:00:00

abstract：:Breastfeeding is a powerful health-promoting behavior. A 2016 Lancet global collaboration to review the health implications of breastfeeding was among the first to consider oral health outcomes. While a role was suggested for breastfeeding in preventing malocclusion, caries was the only included disease condition unfa...

journal_title：Journal of dental research

authors： Peres KG,Chaffee BW,Feldens CA,Flores-Mir C,Moynihan P,Rugg-Gunn A

更新日期：2018-03-01 00:00:00

abstract：:Diet is recognized as one of the most important factors affecting the equilibrium of the oral bacterial flora. Studies related to dental caries development have focused mainly on the effect of carbohydrates. In the present work, using swabbing coupled with an immuno-colony-blot assay, we followed the indigenous oral b...

journal_title：Journal of dental research

authors： Blais JF,Lavoie MC

更新日期：1990-03-01 00:00:00

abstract：:It was recently reported that human periapical cysts (hPCys), a commonly occurring odontogenic cystic lesion of inflammatory origin, contain mesenchymal stem cells (MSCs) with the capacity for self-renewal and multilineage differentiation. In this study, periapical inflammatory cysts were compared with dental pulp to ...

journal_title：Journal of dental research

authors： Marrelli M,Paduano F,Tatullo M

更新日期：2015-06-01 00:00:00

abstract：:It is generally accepted that glass ionomers inhibit secondary caries in vivo, and data from in vitro studies support this effect. The aim of this review was a systematic assessment, from the literature, of clinical evidence for the ability of glass-ionomer restoratives to inhibit secondary caries at the restoration m...

journal_title：Journal of dental research

authors： Randall RC,Wilson NH

更新日期：1999-02-01 00:00:00

abstract：:Over the last hundred years, groundbreaking research in oral microbiology has provided a broad and deep understanding about the oral microbiome, its interactions with our body, and how the community can affect our health, be protective, or lead to the development of dental diseases. During this exciting journey, hypot...

journal_title：Journal of dental research

authors： Colombo APV,Tanner ACR

更新日期：2019-04-01 00:00:00

abstract：:Periodontitis is a complex, multifactorial chronic disease involving continuous interactions among bacteria, host immune/inflammatory responses, and modifying genetic and environmental factors. More than any other cytokine family, the interleukin (IL)-1 family includes key signaling molecules that trigger and perpetua...

journal_title：Journal of dental research

authors： Papathanasiou E,Conti P,Carinci F,Lauritano D,Theoharides TC

更新日期：2020-12-01 00:00:00

abstract：:Dental caries is initiated by demineralization of the tooth surface through acid production by sugar metabolism of supragingival plaque microflora. To elucidate the sugar metabolic system, we used CE-MS to perform metabolomics of the central carbon metabolism, the EMP pathway, the pentose-phosphate pathway, and the TC...

journal_title：Journal of dental research

authors： Takahashi N,Washio J,Mayanagi G

更新日期：2010-12-01 00:00:00

abstract：:We evaluated the predictive and construct validity of a caries activity assessment system associated with the International Caries Detection and Assessment System (ICDAS) in primary teeth. A total of 469 children were reexamined: participants of a caries survey performed 2 yr before (follow-up rate of 73.4%). At basel...

journal_title：Journal of dental research

authors： Guedes RS,Piovesan C,Ardenghi TM,Emmanuelli B,Braga MM,Ekstrand KR,Mendes FM

更新日期：2014-07-01 00:00:00

abstract：:Schoolchildren residing in a fluoride-deficient area were provided either a sodium fluoride (0.1% F) or a nonfluoride dentifrice for home use. About half the children provided each type of dentifrice were also given an initial prophylaxis. Combining the data with regard to the type of dentifrice indicated that the sod...

journal_title：Journal of dental research

authors： Stookey GK,Beiswanger BB

更新日期：1975-01-01 00:00:00