Abstract:
:The ability of human oral bacteria to inhibit Streptococcus mutans was studied under a variety of in vitro conditions using an agar overlay assay. Extensive inherent variability in microbial antagonism by certain organisms was demonstrated. Antagonistic activity was also significantly influenced by changes in the assay conditions.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Deyloff JL,Sanders CCdoi
10.1177/00220345800590110501subject
Has Abstractpub_date
1980-11-01 00:00:00pages
1953-9issue
11eissn
0022-0345issn
1544-0591journal_volume
59pub_type
杂志文章abstract::The histopathologic status of gingival tissue was assessed according to the criteria of Page and Schroeder.(5) Rhodamine-labeled bacteria were used to assess the antigenic specificity of plasma cells in the tissue. Examination of tissue sections revealed that 31.6% of plasma cells in the advanced lesions bound the lab...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034580059S213
更新日期:1980-11-01 00:00:00
abstract::Resin luting of all-ceramic restorations results in increased performance; however, the strengthening mechanism and the role of the mechanical properties of the resin are not fully understood. The hypothesis tested is that ceramic strength enhancement is dependent on the elastic modulus of the resin. Three-point flexu...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910708600606
更新日期:2007-06-01 00:00:00
abstract::When one uses composite resins, the curing contraction, the stiffness of the material, and the strength of the vulnerable dentinal bond are important factors in determining the marginal adaptation of the restoration. Calculations based on these intrinsic material properties have indicated that both bulk placement and ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345880670050901
更新日期:1988-05-01 00:00:00
abstract::The goal of nonrestorative or non- and microinvasive caries treatment (fluoride- and nonfluoride-based interventions) is to manage the caries disease process at a lesion level and minimize the loss of sound tooth structure. The purpose of this systematic review and network meta-analysis was to summarize the available ...
journal_title:Journal of dental research
pub_type: 杂志文章,meta分析
doi:10.1177/0022034518800014
更新日期:2019-01-01 00:00:00
abstract::In an earlier paper on bench-scale simulation of the caries process, it was shown that the passage of ions through ion-permselective barriers could have profound effects on the composition of the solution within the "lesion" at steady state. As indicated in earlier papers, these changes are produced by unequal rates o...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345860650090201
更新日期:1986-09-01 00:00:00
abstract::Dental epithelial progenitor cells differentiate into various cell types during development of tooth germs. To study this mechanism, we produced immortalized dental epithelial progenitor cells derived from the cervical-loop epithelium of a rat lower incisor. The expression patterns of cytokeratin 14, nerve growth fact...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910408300209
更新日期:2004-02-01 00:00:00
abstract::Little is known about the oral health of the frail and home-living elderly. The effects of dentogenic infections on the general condition of the elderly are also unknown. We therefore set out to investigate 191 elderly patients referred to an acute geriatric hospital due to sudden worsening of their general health. Th...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345970760060601
更新日期:1997-06-01 00:00:00
abstract::Stereologic studies of trabecular architecture suggest that the pig mandibular condyle is strongest when loaded supero-inferiorly, and that stress is concentrated in the antero-inferior region (Teng and Herring, 1995). To test these hypotheses, we investigated the uni-axial mechanical properties of 22 pig mandibular c...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345960750110501
更新日期:1996-11-01 00:00:00
abstract::The effects of Escherichia coli endotoxin upon mouse L929 cell proliferation, DNA synthesis, protein synthesis, and proline incorporation were determined. It was found that a level of endotoxin which inhibited cell proliferation prompted a similar inhibition of DNA synthesis and overall cell protein synthesis. In cont...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345790580061301
更新日期:1979-06-01 00:00:00
abstract::These studies defined the normal and hormonally altered development of activity for tyrosine hydroxylase (T-OH), the rate-limiting enzyme in catecholamine biosynthesis (Levitt et al., 1965), and choline acetyltransferase activity (CAT) in the male rat superior cervical ganglion (SCG). Additionally, salivary gland weig...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345870660030901
更新日期:1987-03-01 00:00:00
abstract::Gingival epithelium is a site of active trafficking of Langerhans cells (LCs), while the lamina propria in chronic periodontitis (CP) contains CD83+ mature dendritic cells (mDCs) and CD4+ T-cells. The immune cells that contribute to the mDCs, and whether mDCs engage with T-cells in situ, are unclear. Using several imm...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910308200915
更新日期:2003-09-01 00:00:00
abstract::Temperature elevations were measured in the pulp chamber of full cast crown preparations during impression taking with modelling compound in copper bands. Uncontrolled flaming, controlled flaming, and water heating of the bands produced temperatures of 53, 44, and 41.5 C, respectively. The time involved in restoring t...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:
更新日期:1975-03-01 00:00:00
abstract::Moderate elevation of serum C-reactive protein (CRP) is a risk factor for cardiovascular disease among apparently healthy individuals, although factors that create this inflammatory response in the absence of systemic illness have not been clarified. This study aimed to: (1) evaluate associations among periodontal dis...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345000790010701
更新日期:2000-01-01 00:00:00
abstract::The extent of dental tissue destruction during the treatment of white spot lesions (WSLs) increases with the severity of the lesion. If the depth and shape of WSLs can be predicted with a noninvasive diagnostic method before dental caries treatment, more conservative interventions can be planned. Given the superiority...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034518811642
更新日期:2019-03-01 00:00:00
abstract::Mandibular prognathism (MP) is a recognizable phenotype associated with dentoskeletal class III malocclusion. MP is a complex genetic trait, although familial recurrence also suggests the contribution of single inherited variations. To date, the genetic causes of MP have been investigated using linkage analysis or ass...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034515572190
更新日期:2015-04-01 00:00:00
abstract::Recent advances in molecular biology have facilitated analyses of the oral microbiome ("Who are they?"); however, its functions (e.g., metabolic activities) are poorly understood ("What are they doing?"). This review aims to summarize our current understanding of the metabolism of the oral microbiome. Saccharolytic ba...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/0022034515606045
更新日期:2015-12-01 00:00:00
abstract::Oral bacteria, including Streptococcus mutans and Streptococcus salivarius, contribute to tooth decay and plaque formation; therefore, it is essential to develop strategies to prevent dental caries and plaque formation. We recently showed that organo-selenium compounds covalently attached to different biomaterials inh...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034513482141
更新日期:2013-05-01 00:00:00
abstract::Breastfeeding is a powerful health-promoting behavior. A 2016 Lancet global collaboration to review the health implications of breastfeeding was among the first to consider oral health outcomes. While a role was suggested for breastfeeding in preventing malocclusion, caries was the only included disease condition unfa...
journal_title:Journal of dental research
pub_type: 杂志文章,评审
doi:10.1177/0022034517738925
更新日期:2018-03-01 00:00:00
abstract::IL-18 is a pro-inflammatory cytokine that is important in the regulation of T-cells and is elevated in inflammatory disorders such as periodontal disease. Vasoactive intestinal peptide (VIP) modulates immune responses to the periodontal pathogen Porphyromonas gingivalis (Pg). Our objective was to investigate the effec...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910708600915
更新日期:2007-09-01 00:00:00
abstract::The effect of toothbrushes on soft tissue abrasion was measured using hamster cheek pouch tissue brushed mechanically for various intervals. The detection of protein removed during brushing was used as an index of tissue abrasion. The method was found to be sensitive in detecting the effects of brush load, number of s...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345770560070301
更新日期:1977-07-01 00:00:00
abstract::Weanling rice rats were fed either standard laboratory chow or Diet 2000. The animals were sacrificed at 4, 8, 12, and 15 weeks. There was an increasing amount of exposed root surface and root surface caries with age in the animals fed Diet 2000. There was exposed root surface but no caries in the animals fed laborato...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345770560091701
更新日期:1977-09-01 00:00:00
abstract::The efficacy of a new remineralization system was determined in vivo by maintaining a low concentration of approximately 1 ppm fluoride for 48 hrs against a demineralized human tooth. Human subjects were selected who wore removable partial dentures containing two or more of the demineralized teeth with film system. Th...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345800590030501
更新日期:1980-03-01 00:00:00
abstract::It has often been hypothesized that a large tongue leads to an enlargement of the mandible and therefore contributes to the development of mandibular prognathism. We examined (1) whether the tongue volume in human subjects with mandibular prognathism was larger than that in subjects with good occlusion and (2) whether...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345960750120701
更新日期:1996-12-01 00:00:00
abstract::In the absence of active pulmonary disease, mycobacterial infection frequently causes arthritis and can be considered to initiate autoimmune diseases such as rheumatoid arthritis. Temporomandibular disorder (TMD) is a disease in which pain and impaired mandibular movement appear to arise directly from degenerative or ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345000790100401
更新日期:2000-10-01 00:00:00
abstract::The human temporalis and masseter muscles are not activated homogeneously during static bite force tasks. In this study, we studied the possible existence of regional differences in these muscles under dynamic conditions. Electromyographic (EMG) activity was recorded by means of bipolar fine-wire electrodes. Six elect...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345950740061201
更新日期:1995-06-01 00:00:00
abstract::Conservative techniques for improving the appearance of discolored teeth have become popular in the past decade. These include: in-office bleaching with 30% hydrogen peroxide, which is applied on etched enamel with a gauze pad and then exposed to a bleaching light; home bleaching with a mild form of peroxide, such as ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345930720011001
更新日期:1993-01-01 00:00:00
abstract::Biological mediators have been used to enhance periodontal regeneration. The aim of this prospective randomized controlled study was to evaluate the safety and effectiveness of 3 doses of fibroblast growth factor 2 (FGF-2) when combined with a β-tricalcium phosphate (β-TCP) scaffold carrier placed in vertical infrabon...
journal_title:Journal of dental research
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1177/0022034516632497
更新日期:2016-05-01 00:00:00
abstract::We have investigated the role of the activation of nuclear poly(ADP-ribose) polymerase (PARP) enzyme, a mediator of downstream nitric oxide toxicity, using a combined approach of pharmacological inhibition and genetic disruption in a ligature-induced-periodontitis model in rats and mice. Immunohistochemical analysis r...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910308201210
更新日期:2003-12-01 00:00:00
abstract::The ability of physiological amounts of lysozyme to de-chain two serotype c strains of Streptococcus mutans was determined. Both human and hen lysozymes were equally effective in chain breakage of S. mutans DPR and S. mutans DJR. De-chaining did not affect growth of cultures, but resulted in finely dispersed suspensio...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345850640010901
更新日期:1985-01-01 00:00:00
abstract::We conducted a school-based parallel cluster randomized controlled trial with 36-month follow-up of children aged 7 to 8 years. Primary schools were randomly assigned to 2 groups: 3 applications of fluoride varnish (22,600 ppm) each year or no intervention. The primary outcome was DFS increment in the first permanent ...
journal_title:Journal of dental research
pub_type: 杂志文章,随机对照试验
doi:10.1177/0022034511422063
更新日期:2011-11-01 00:00:00