Epidemiology and biology of a herpesvirus in rabies endemic vampire bat populations.

abstract：:Oceanic anoxic events have been associated with warm climates in Earth history, and there are concerns that current ocean deoxygenation may eventually lead to anoxia. Here we show results of a multi-millennial global-warming simulation that reveal, after a transitory deoxygenation, a marine oxygen inventory 6% higher ...

journal_title：Nature communications

authors： Oschlies A,Koeve W,Landolfi A,Kähler P

更新日期：2019-06-26 00:00:00

abstract：:Receptor families of the innate immune response engage in 'cross-talk' to tailor optimal immune responses against invading pathogens. However, these responses are subject to multiple levels of regulation to keep in check aberrant inflammatory signals. Here, we describe a role for the orphan receptor interleukin-17 rec...

journal_title：Nature communications

authors： Mellett M,Atzei P,Bergin R,Horgan A,Floss T,Wurst W,Callanan JJ,Moynagh PN

更新日期：2015-03-26 00:00:00

abstract：:Ferroptosis is a newly defined form of regulated cell death characterized by the iron-dependent accumulation of lipid hydroperoxides. Erastin, the ferroptosis activator, binds to voltage-dependent anion channels VDAC2 and VDCA3, but treatment with erastin can result in the degradation of the channels. Here, the author...

journal_title：Nature communications

authors： Yang Y,Luo M,Zhang K,Zhang J,Gao T,Connell DO,Yao F,Mu C,Cai B,Shang Y,Chen W

更新日期：2020-01-23 00:00:00

abstract：:Apicomplexans are obligate intracellular parasites that scavenge essential nutrients from their hosts via transporter proteins on their plasma membrane. The identities of the transporters that mediate amino acid uptake into apicomplexans are unknown. Here we demonstrate that members of an apicomplexan-specific protein...

journal_title：Nature communications

authors： Rajendran E,Hapuarachchi SV,Miller CM,Fairweather SJ,Cai Y,Smith NC,Cockburn IA,Bröer S,Kirk K,van Dooren GG

更新日期：2017-02-16 00:00:00

abstract：:Electronic structure heterogeneities are ubiquitous in two-dimensional graphene and profoundly impact the transport properties of this material. Here we show the mapping of discrete electronic domains within a single graphene sheet using scanning transmission X-ray microscopy in conjunction with ab initio density func...

journal_title：Nature communications

authors： Schultz BJ,Patridge CJ,Lee V,Jaye C,Lysaght PS,Smith C,Barnett J,Fischer DA,Prendergast D,Banerjee S

更新日期：2011-06-28 00:00:00

abstract：:Materials hosting magnetic skyrmions at room temperature could enable compact and energetically-efficient storage such as racetrack memories, where information is coded by the presence/absence of skyrmions forming a moving chain through the device. The skyrmion Hall effect leading to their annihilation at the racetrac...

journal_title：Nature communications

authors： Mandru AO,Yıldırım O,Tomasello R,Heistracher P,Penedo M,Giordano A,Suess D,Finocchio G,Hug HJ

更新日期：2020-12-11 00:00:00

abstract：:Impaired lung function is often caused by cigarette smoking, making it challenging to disentangle its role in lung cancer susceptibility. Investigation of the shared genetic basis of these phenotypes in the UK Biobank and International Lung Cancer Consortium (29,266 cases, 56,450 controls) shows that lung cancer is ge...

journal_title：Nature communications

authors： Kachuri L,Johansson M,Rashkin SR,Graff RE,Bossé Y,Manem V,Caporaso NE,Landi MT,Christiani DC,Vineis P,Liu G,Scelo G,Zaridze D,Shete SS,Albanes D,Aldrich MC,Tardón A,Rennert G,Chen C,Goodman GE,Doherty JA,Bickebö

更新日期：2020-01-07 00:00:00

abstract：:In recent years, there has been marked increase in research aimed to introduce alkali vapours into guided-wave configurations. Owing to the significant reduction in device dimensions, the increase in density of states, the interaction with surfaces and primarily the high intensities carried along the structure, a plet...

journal_title：Nature communications

authors： Stern L,Desiatov B,Mazurski N,Levy U

更新日期：2017-02-09 00:00:00

abstract：:Imaging the optical properties of individual nanosystems beyond fluorescence can provide a wealth of information. However, the minute signals for absorption and dispersion are challenging to observe, and only specialized techniques requiring sophisticated noise rejection are available. Here we use signal enhancement i...

journal_title：Nature communications

authors： Mader M,Reichel J,Hänsch TW,Hunger D

更新日期：2015-06-24 00:00:00

abstract：:Optical tracking is often combined with conventional flat panel solar cells to maximize electrical power generation over the course of a day. However, conventional trackers are complex and often require costly and cumbersome structural components to support system weight. Here we use kirigami (the art of paper cutting...

journal_title：Nature communications

authors： Lamoureux A,Lee K,Shlian M,Forrest SR,Shtein M

更新日期：2015-09-08 00:00:00

abstract：:Anatomical atlases in standard coordinates are necessary for the interpretation and integration of research findings in a common spatial context. However, the two most-used mouse brain atlases, the Franklin-Paxinos (FP) and the common coordinate framework (CCF) from the Allen Institute for Brain Science, have accumula...

journal_title：Nature communications

authors： Chon U,Vanselow DJ,Cheng KC,Kim Y

更新日期：2019-11-07 00:00:00

abstract：:The direct transformation of cellulose, which is the main component of lignocellulosic biomass, into building-block chemicals is the key to establishing biomass-based sustainable chemical processes. Only limited successes have been achieved for such transformations under mild conditions. Here we report the simple and ...

journal_title：Nature communications

authors： Wang Y,Deng W,Wang B,Zhang Q,Wan X,Tang Z,Wang Y,Zhu C,Cao Z,Wang G,Wan H

更新日期：2013-01-01 00:00:00

abstract：:Epistasis emerges when the effects of an amino acid depend on the identities of interacting residues. This phenomenon shapes fitness landscapes, which have the power to reveal evolutionary paths and inform evolution of desired functions. However, there is a need for easily implemented, high-throughput methods to captu...

journal_title：Nature communications

authors： Yoo JI,Daugherty PS,O'Malley MA

更新日期：2020-02-04 00:00:00

abstract：:Human-pluripotent-stem-cell-derived kidney cells (hPSC-KCs) have important potential for disease modelling and regeneration. Whether the hPSC-KCs can reconstitute tissue-specific phenotypes is currently unknown. Here we show that hPSC-KCs self-organize into kidney organoids that functionally recapitulate tissue-specif...

journal_title：Nature communications

authors： Freedman BS,Brooks CR,Lam AQ,Fu H,Morizane R,Agrawal V,Saad AF,Li MK,Hughes MR,Werff RV,Peters DT,Lu J,Baccei A,Siedlecki AM,Valerius MT,Musunuru K,McNagny KM,Steinman TI,Zhou J,Lerou PH,Bonventre JV

更新日期：2015-10-23 00:00:00

abstract：:Histone H2AX and MDC1 are key DNA repair and DNA-damage signalling proteins. When DNA double-strand breaks (DSBs) occur, H2AX is phosphorylated and then recruits MDC1, which in turn serves as a docking platform to promote the localization of other factors, including 53BP1, to DSB sites. Here, by using CRISPR-Cas9 engi...

journal_title：Nature communications

authors： Salguero I,Belotserkovskaya R,Coates J,Sczaniecka-Clift M,Demir M,Jhujh S,Wilson MD,Jackson SP

更新日期：2019-11-15 00:00:00

abstract：:The TORC1 complex controls cell growth upon integrating nutritional signals including amino-acid availability. TORC1 notably adapts the plasma membrane protein content by regulating arrestin-mediated endocytosis of amino-acid transporters. Here we demonstrate that TORC1 further fine tunes the inherent activity of the ...

journal_title：Nature communications

authors： Boeckstaens M,Llinares E,Van Vooren P,Marini AM

更新日期：2014-01-01 00:00:00

abstract：:Photosynthesis is nature's route to convert intermittent solar irradiation into storable energy, while its use for an industrial energy supply is impaired by low efficiency. Artificial photosynthesis provides a promising alternative for efficient robust carbon-neutral renewable energy generation. The approach of direc...

journal_title：Nature communications

authors： May MM,Lewerenz HJ,Lackner D,Dimroth F,Hannappel T

更新日期：2015-09-15 00:00:00

abstract：:Enhancers are critical for developmental stage-specific gene expression, but their dynamic regulation in plants remains poorly understood. Here we compare genome-wide localization of H3K27ac, chromatin accessibility and transcriptomic changes during flower development in Arabidopsis. H3K27ac prevalently marks promoter...

journal_title：Nature communications

authors： Yan W,Chen D,Schumacher J,Durantini D,Engelhorn J,Chen M,Carles CC,Kaufmann K

更新日期：2019-04-12 00:00:00

abstract：:The current trends of crop yield improvements are not expected to meet the projected rise in demand. Genomic selection uses molecular markers and machine learning to identify superior genotypes with improved traits, such as growth. Plant growth directly depends on rates of metabolic reactions which transform nutrients...

journal_title：Nature communications

authors： Tong H,Küken A,Nikoloski Z

更新日期：2020-05-15 00:00:00

abstract：:To cause food-borne botulism, botulinum neurotoxin (BoNT) in the gastrointestinal lumen must traverse the intestinal epithelial barrier. However, the mechanism by which BoNT crosses the intestinal epithelial barrier remains unclear. BoNTs are produced along with one or more non-toxic components, with which they form p...

journal_title：Nature communications

authors： Matsumura T,Sugawara Y,Yutani M,Amatsu S,Yagita H,Kohda T,Fukuoka S,Nakamura Y,Fukuda S,Hase K,Ohno H,Fujinaga Y

更新日期：2015-02-17 00:00:00

abstract：:Metal ions can serve as a centre of molecular motions due to their coordination geometry, reversible bonding nature and external stimuli responsiveness. Such essential features of metal ions have been utilized for metal-mediated molecular machines with the ability to motion switch via metallation/demetallation or coor...

journal_title：Nature communications

authors： Ube H,Yasuda Y,Sato H,Shionoya M

更新日期：2017-02-08 00:00:00

abstract：:Research on surface plasmon resonance coupling of metallic nanostructures is an important area in the field of plasmonics because distinctive collective optical properties can be realized that are different from the individual constituents. Here we report the localized surface plasmon resonance of hybrid metal-organic...

journal_title：Nature communications

authors： Jung I,Kim M,Kwak M,Kim G,Jang M,Kim SM,Park DJ,Park S

更新日期：2018-03-08 00:00:00

abstract：:Stem rust is an important disease of wheat that can be controlled using resistance genes. The gene SuSr-D1 identified in cultivar 'Canthatch' suppresses stem rust resistance. SuSr-D1 mutants are resistant to several races of stem rust that are virulent on wild-type plants. Here we identify SuSr-D1 by sequencing flow-s...

journal_title：Nature communications

authors： Hiebert CW,Moscou MJ,Hewitt T,Steuernagel B,Hernández-Pinzón I,Green P,Pujol V,Zhang P,Rouse MN,Jin Y,McIntosh RA,Upadhyaya N,Zhang J,Bhavani S,Vrána J,Karafiátová M,Huang L,Fetch T,Doležel J,Wulff BBH,Lagudah E,

更新日期：2020-02-28 00:00:00

abstract：:Neural crest migration is critical to its physiological function. Mechanisms controlling mammalian neural crest migration are comparatively unknown, due to difficulties accessing this cell population in vivo. Here we report requirements of glycogen synthase kinase 3 (GSK3) in regulating the neural crest in Xenopus and...

journal_title：Nature communications

authors： Gonzalez Malagon SG,Lopez Muñoz AM,Doro D,Bolger TG,Poon E,Tucker ER,Adel Al-Lami H,Krause M,Phiel CJ,Chesler L,Liu KJ

更新日期：2018-03-19 00:00:00

abstract：:High strength and high ductility are often mutually exclusive properties for structural metallic materials. This is particularly important for aluminum (Al)-based alloys which are widely commercially employed. Here, we introduce a hierarchical nanostructured Al alloy with a structure of Al nanograins surrounded by nan...

journal_title：Nature communications

authors： Wu G,Liu C,Sun L,Wang Q,Sun B,Han B,Kai JJ,Luan J,Liu CT,Cao K,Lu Y,Cheng L,Lu J

更新日期：2019-11-08 00:00:00

abstract：:Emerging evidence indicates that osteoclasts direct osteoblastic bone formation. MicroRNAs (miRNAs) have a crucial role in regulating osteoclast and osteoblast function. However, whether miRNAs mediate osteoclast-directed osteoblastic bone formation is mostly unknown. Here, we show that increased osteoclastic miR-214-...

journal_title：Nature communications

authors： Li D,Liu J,Guo B,Liang C,Dang L,Lu C,He X,Cheung HY,Xu L,Lu C,He B,Liu B,Shaikh AB,Li F,Wang L,Yang Z,Au DW,Peng S,Zhang Z,Zhang BT,Pan X,Qian A,Shang P,Xiao L,Jiang B,Wong CK,Xu J,Bian Z,Liang Z,

更新日期：2016-03-07 00:00:00

abstract：:Vibrio cholerae, responsible for acute gastroenteritis secretes a large multifunctional-autoprocessing repeat-in-toxin (MARTX) toxin linked to evasion of host immune system, facilitating colonization of small intestine. Unlike other effector domains of the multifunctional toxin that target cytoskeleton, the function o...

journal_title：Nature communications

authors： Agarwal S,Kim H,Chan RB,Agarwal S,Williamson R,Cho W,Paolo GD,Satchell KJ

更新日期：2015-10-26 00:00:00

abstract：:Due to the surge of natural gas production, feedstocks for chemicals shift towards lighter hydrocarbons, particularly methane. The success of a Gas-to-Chemicals process via synthesis gas (CO and H2) depends on the ability of catalysts to suppress methane and carbon dioxide formation. We designed a Co/Mn/Na/S catalyst,...

journal_title：Nature communications

authors： Xie J,Paalanen PP,van Deelen TW,Weckhuysen BM,Louwerse MJ,de Jong KP

更新日期：2019-01-11 00:00:00

abstract：:Cancer proteogenomics promises new insights into cancer biology and treatment efficacy by integrating genomics, transcriptomics and protein profiling including modifications by mass spectrometry (MS). A critical limitation is sample input requirements that exceed many sources of clinically important material. Here we ...

journal_title：Nature communications

authors： Satpathy S,Jaehnig EJ,Krug K,Kim BJ,Saltzman AB,Chan DW,Holloway KR,Anurag M,Huang C,Singh P,Gao A,Namai N,Dou Y,Wen B,Vasaikar SV,Mutch D,Watson MA,Ma C,Ademuyiwa FO,Rimawi MF,Schiff R,Hoog J,Jacobs S,Malov

更新日期：2020-01-27 00:00:00

abstract：:In areas where malaria epidemiology is spatially and temporally heterogeneous, human-mediated parasite importation can result in non-locally acquired clinical cases and outbreaks in low-transmission areas. Using mobility estimates derived from the mobile phone data and spatial malaria prevalence data, we identify trav...

journal_title：Nature communications

authors： Ihantamalala FA,Herbreteau V,Rakotoarimanana FMJ,Rakotondramanga JM,Cauchemez S,Rahoilijaona B,Pennober G,Buckee CO,Rogier C,Metcalf CJE,Wesolowski A

更新日期：2018-09-25 00:00:00