DXA reference values and anthropometric screening for visceral obesity in Western Australian adults.

Abstract:

:Limited reference values exist for visceral adipose tissue (VAT) mass measured by DXA. The objectives of this study were to provide reference values for DXA-derived VAT mass and compare the association with anthropometry measures. The study cohort comprised 677 men and 738 women aged 18-65 years from Western Australia. Whole-body scans using a GE Lunar iDXA and anthropometry measures were collected. Reference percentile data were stratified by sex and age. Correlation analysis compared DXA-derived and anthropometry variables. Specificity, sensitivity, and Youden's Index were used to evaluate the ability of anthropometric thresholds to predict individuals with high VAT. In men, waist circumference (WC), waist-hip ratio, and waist-height ratio (WHtR) had 'high' correlations with VAT mass. In women, only WHtR was 'highly' correlated with VAT mass. Overweight thresholds for WC, along with a body mass index of 25.0 kg/m2 in women, had the highest combination of sensitivity and specificity when using anthropometry measures to identify individuals with high VAT mass. We provide the first reference data sets for DXA-derived VAT mass among Western Australians. Excessive VAT mass may be identified in men using the overweight WC threshold and in women using both the overweight BMI and WC thresholds.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Staynor JMD,Smith MK,Donnelly CJ,Sallam AE,Ackland TR

doi

10.1038/s41598-020-73631-x

subject

Has Abstract

pub_date

2020-10-30 00:00:00

pages

18731

issue

1

issn

2045-2322

pii

10.1038/s41598-020-73631-x

journal_volume

10

pub_type

杂志文章
  • Intratumor heterogeneity inferred from targeted deep sequencing as a prognostic indicator.

    abstract::Tumor genetic heterogeneity may underlie poor clinical outcomes because diverse subclones could be comprised of metastatic and drug resistant cells. Targeted deep sequencing has been used widely as a diagnostic tool to identify actionable mutations in cancer patients. In this study, we evaluated the clinical utility o...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-41098-0

    authors: Oh BY,Shin HT,Yun JW,Kim KT,Kim J,Bae JS,Cho YB,Lee WY,Yun SH,Park YA,Park YH,Im YH,Lee J,Joung JG,Kim HC,Park WY

    更新日期:2019-03-14 00:00:00

  • IL-17A is produced by breast cancer TILs and promotes chemoresistance and proliferation through ERK1/2.

    abstract::The proinflammatory cytokine Interleukin 17A (hereafter named IL-17A) or IL-17A producing cells are elevated in breast tumors environment and correlate with poor prognosis. Increased IL-17A is associated with ER(-) or triple negative tumors and reduced Disease Free Survival. However, the pathophysiological role of IL-...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep03456

    authors: Cochaud S,Giustiniani J,Thomas C,Laprevotte E,Garbar C,Savoye AM,Curé H,Mascaux C,Alberici G,Bonnefoy N,Eliaou JF,Bensussan A,Bastid J

    更新日期:2013-12-09 00:00:00

  • The neural transfer effect of working memory training to enhance hedonic processing in individuals with social anhedonia.

    abstract::Anhedonia, the diminished ability to experience pleasure, is a challenging negative symptom in patients with schizophrenia and can be observed in at-risk individuals with schizotypy. Deficits in hedonic processing have been postulated to be related to decreased motivation to engage in potentially rewarding events. It ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep35481

    authors: Li X,Li Z,Li K,Zeng YW,Shi HS,Xie WL,Yang ZY,Lui SS,Cheung EF,Leung AW,Chan RC

    更新日期:2016-10-18 00:00:00

  • Treatment of Coral Wounds by Combining an Antiseptic Bilayer Film and an Injectable Antioxidant Biopolymer.

    abstract::Coral reefs are vital for the marine ecosystem and their potential disappearance can have unequivocal consequences on our environment. Aside from pollution-related threats (changes in water temperature, plastics, and acidity), corals can be injured by diseases, predators, humans and other invasive species. Diseases pl...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-57980-1

    authors: Contardi M,Montano S,Liguori G,Heredia-Guerrero JA,Galli P,Athanassiou A,Bayer IS

    更新日期:2020-01-22 00:00:00

  • DNA methylation landscape of ocular tissue relative to matched peripheral blood.

    abstract::Epigenetic variation is implicated in a range of non-communicable diseases, including those of the eye. However, investigating the role of epigenetic variation in central tissues, such as eye or brain, remains problematic and peripheral tissues are often used as surrogates. In this study, matched human blood and eye t...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep46330

    authors: Hewitt AW,Januar V,Sexton-Oates A,Joo JE,Franchina M,Wang JJ,Liang H,Craig JE,Saffery R

    更新日期:2017-04-13 00:00:00

  • Reversal of established liver fibrosis by IC-2-engineered mesenchymal stem cell sheets.

    abstract::Chronic hepatitis viral infection, alcoholic intoxication, and obesity cause liver fibrosis, which progresses to decompensated liver cirrhosis, a disease for which medical demands cannot be met. Since there are currently no approved anti-fibrotic therapies for established liver fibrosis, the development of novel modal...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-43298-0

    authors: Itaba N,Kono Y,Watanabe K,Yokobata T,Oka H,Osaki M,Kakuta H,Morimoto M,Shiota G

    更新日期:2019-05-02 00:00:00

  • Constructive approach for synthesis of a functional IgG using a reconstituted cell-free protein synthesis system.

    abstract::IgG is an indispensable biological experimental tool as well as a widely-used therapeutic protein. However, cell culture-based expression of monoclonal IgG is costly and time-consuming, making this process difficult to use for high-throughput screening in early-stage evaluation of biologics. With the goal of establish...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-36691-8

    authors: Murakami S,Matsumoto R,Kanamori T

    更新日期:2019-01-24 00:00:00

  • A new approach for highly accurate, remote temperature probing using magnetic nanoparticles.

    abstract::In this study, we report on a new approach for remote temperature probing that provides accuracy as good as 0.017°C (0.0055% accuracy) by measuring the magnetisation curve of magnetic nanoparticles. We included here the theoretical model construction and the inverse calculation method, and explored the impact caused b...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep06338

    authors: Zhong J,Liu W,Kong L,Morais PC

    更新日期:2014-10-15 00:00:00

  • Gram Negative Bacterial Inflammation Ameliorated by the Plasma Protein Beta 2-Glycoprotein I.

    abstract::Lipopolysaccharide (LPS) is a major component of the outer wall of gram negative bacteria. In high doses LPS contributes to the inflammation in gram negative sepsis, and in low doses contributes to the low grade inflammation characteristic of the metabolic syndrome. We wanted to assess the role of beta2-glycoprotein I...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep33656

    authors: Zhou S,Chen G,Qi M,El-Assaad F,Wang Y,Dong S,Chen L,Yu D,Weaver JC,Beretov J,Krilis SA,Giannakopoulos B

    更新日期:2016-09-27 00:00:00

  • Moonlight controls lunar-phase-dependency and regular oscillation of clock gene expressions in a lunar-synchronized spawner fish, Goldlined spinefoot.

    abstract::Goldlined spinefoot, Siganus guttatus, inhabits tropical and subtropical waters and synchronizes its spawning around the first quarter moon likely using an hourglass-like lunar timer. In previous studies, we have found that clock genes (Cryptochrome3 and Period1) could play the role of state variable in the diencephal...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-24538-1

    authors: Takeuchi Y,Kabutomori R,Yamauchi C,Miyagi H,Takemura A,Okano K,Okano T

    更新日期:2018-04-18 00:00:00

  • Yeast two-hybrid screening for proteins that interact with PFT in wheat.

    abstract::Fusarium head blight (FHB) is a devastating disease of wheat worldwide. Fhb1 is the most consistently reported quantitative trait locus (QTL) for FHB resistance breeding. A pore-forming toxin-like (PFT) gene at Fhb1 was first cloned by map-based cloning and found to confer FHB resistance in wheat. Proteins often inter...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-52030-x

    authors: He Y,Wu L,Liu X,Zhang X,Jiang P,Ma H

    更新日期:2019-10-29 00:00:00

  • Crosstalk between Hedgehog pathway and energy pathways in human adipose-derived stem cells: A deep sequencing analysis of polysome-associated RNA.

    abstract::Adult stem cells are considered promising candidates for cellular therapies due to their capacity to differentiate and self-renew. Differentiation leads to changes in the metabolism, structure, and gene expression patterns of cells. Hedgehog is one of the pathways that is involved in the enhancement of osteogenesis an...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-26533-y

    authors: Shigunov P,Balvedi LT,Santos MDM,Herai RH,de Aguiar AM,Dallagiovanna B

    更新日期:2018-05-30 00:00:00

  • Mdm2 enhances ligase activity of parkin and facilitates mitophagy.

    abstract::Loss-of-function mutations in the E3 ubiquitin ligase parkin have been implicated in the death of dopaminergic neurons in the substantia nigra, which is the root cause of dopamine deficit in the striatum in Parkinson's disease. Parkin ubiquitinates proteins on mitochondria that lost membrane potential, promoting the e...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-61796-4

    authors: Kook S,Zhan X,Thibeault K,Ahmed MR,Gurevich VV,Gurevich EV

    更新日期:2020-03-19 00:00:00

  • Maternally expressed NLRP2 links the subcortical maternal complex (SCMC) to fertility, embryogenesis and epigenetic reprogramming.

    abstract::Mammalian parental genomes contribute differently to early embryonic development. Before activation of the zygotic genome, the maternal genome provides all transcripts and proteins required for the transition from a highly specialized oocyte to a pluripotent embryo. Depletion of these maternally-encoded transcripts fr...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep44667

    authors: Mahadevan S,Sathappan V,Utama B,Lorenzo I,Kaskar K,Van den Veyver IB

    更新日期:2017-03-20 00:00:00

  • Human GV oocytes generated by mitotically active germ cells obtained from follicular aspirates.

    abstract::Human female germline stem cells (FGSCs) have opened new opportunities for understanding human oogenesis, delaying menopause, treating infertility, and providing a new strategy for preserving fertility. However, the shortage of adult human ovaries tissues available impedes their future investigations and clinical appl...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep28218

    authors: Ding X,Liu G,Xu B,Wu C,Hui N,Ni X,Wang J,Du M,Teng X,Wu J

    更新日期:2016-06-30 00:00:00

  • Chronic kidney disease attenuates the impact of obesity on quality of life.

    abstract::The impact of obesity on health-related quality of life (HRQoL) in chronic kidney disease (CKD) population has not been elucidated, despite the impairment of HRQoL in the obese among general population. We hypothesized that the impact of obesity on HRQoL might be confounded by impaired renal function in CKD population...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-59382-9

    authors: Suh SH,Choi HS,Kim CS,Bae EH,Ma SK,Lee DH,Kim SW

    更新日期:2020-02-11 00:00:00

  • Biological surface properties in extracellular vesicles and their effect on cargo proteins.

    abstract::Ultracentrifugationon sucrose density gradientappears to be the best purification protocol for extracellular vesicle (EVs) purification. After this step, to reduce disulfide bridges linking exogenous proteins to the vesicles, the collected samples are routinely washed and treated with dithiothreitol (DTT). Such incuba...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-47598-3

    authors: Santucci L,Bruschi M,Del Zotto G,Antonini F,Ghiggeri GM,Panfoli I,Candiano G

    更新日期:2019-09-10 00:00:00

  • A decadal analysis of bioeroding sponge cover on the inshore Great Barrier Reef.

    abstract::Decreasing coral cover on the Great Barrier Reef (GBR) may provide opportunities for rapid growth and expansion of other taxa. The bioeroding sponges Cliona spp. are strong competitors for space and may take advantage of coral bleaching, damage, and mortality. Benthic surveys of the inshore GBR (2005-2014) revealed th...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-02196-z

    authors: Ramsby BD,Hoogenboom MO,Whalan S,Webster NS,Thompson A

    更新日期:2017-06-02 00:00:00

  • Honokiol suppresses TNF-α-induced neutrophil adhesion on cerebral endothelial cells by disrupting polyubiquitination and degradation of IκBα.

    abstract::Adhesion molecules expressed on cerebral endothelial cells (ECs) mediate leukocyte recruitment and play a significant role in cerebral inflammation. Increased levels of adhesion molecules on the EC surface induce leukocyte infiltration into inflammatory areas and are thus hallmarkers of inflammation. Honokiol, isolate...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep26554

    authors: Chen PJ,Wang YL,Kuo LM,Lin CF,Chen CY,Tsai YF,Shen JJ,Hwang TL

    更新日期:2016-05-23 00:00:00

  • Classification of Articulator Movements and Movement Direction from Sensorimotor Cortex Activity.

    abstract::For people suffering from severe paralysis, communication can be difficult or nearly impossible. Technology systems called brain-computer interfaces (BCIs) are being developed to assist these people with communication by using their brain activity to control a computer without any muscle activity. To benefit the devel...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-50834-5

    authors: Salari E,Freudenburg ZV,Branco MP,Aarnoutse EJ,Vansteensel MJ,Ramsey NF

    更新日期:2019-10-02 00:00:00

  • A simple, rapid, low-cost technique for naked-eye detection of urine-isolated TMPRSS2:ERG gene fusion RNA.

    abstract::The TMPRSS2:ERG gene fusion is one of a series of highly promising prostate cancer (PCa) biomarker alternatives to the controversial serum PSA. Current methods for detecting TMPRSS2:ERG are limited in terms of long processing time, high cost and the need for specialized equipment. Thus, there is an unmet need for less...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep30722

    authors: Koo KM,Wee EJ,Mainwaring PN,Trau M

    更新日期:2016-07-29 00:00:00

  • Safety and Metabolism of Long-term Administration of NIAGEN (Nicotinamide Riboside Chloride) in a Randomized, Double-Blind, Placebo-controlled Clinical Trial of Healthy Overweight Adults.

    abstract::Nicotinamide riboside (NR) is a newly discovered nicotinamide adenine dinucleotide (NAD+) precursor vitamin. A crystal form of NR chloride termed NIAGEN is generally recognized as safe (GRAS) for use in foods and the subject of two New Dietary Ingredient Notifications for use in dietary supplements. To evaluate the ki...

    journal_title:Scientific reports

    pub_type: 杂志文章,随机对照试验

    doi:10.1038/s41598-019-46120-z

    authors: Conze D,Brenner C,Kruger CL

    更新日期:2019-07-05 00:00:00

  • Covariance statistics and network analysis of brain PET imaging studies.

    abstract::The analysis of structural and functional neuroimaging data using graph theory has increasingly become a popular approach for visualising and understanding anatomical and functional relationships between different cerebral areas. In this work we applied a network-based approach for brain PET studies using population-b...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-39005-8

    authors: Veronese M,Moro L,Arcolin M,Dipasquale O,Rizzo G,Expert P,Khan W,Fisher PM,Svarer C,Bertoldo A,Howes O,Turkheimer FE

    更新日期:2019-02-21 00:00:00

  • Single-crystalline, wormlike hematite photoanodes for efficient solar water splitting.

    abstract::A hematite photoanode showing a stable, record-breaking performance of 4.32 mA/cm² photoelectrochemical water oxidation current at 1.23 V vs. RHE under simulated 1-sun (100 mW/cm²) irradiation is reported. This photocurrent corresponds to ca. 34% of the maximum theoretical limit expected for hematite with a band gap o...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep02681

    authors: Kim JY,Magesh G,Youn DH,Jang JW,Kubota J,Domen K,Lee JS

    更新日期:2013-01-01 00:00:00

  • Gene-activated matrix/bone marrow-derived mesenchymal stem cells constructs regenerate sweat glands-like structure in vivo.

    abstract::It is a significant challenge to regenerate full-thickness skin defects with sweat glands. Various skin substitutes have been developed to resolve this issue with minimal success. In this study, to yield a novel construct for in situ regeneration of sweat glands, the collagen-chitosan porous scaffold was combined with...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-17967-x

    authors: Kolakshyapati P,Li X,Chen C,Zhang M,Tan W,Ma L,Gao C

    更新日期:2017-12-15 00:00:00

  • Effects of Lutein Supplementation in Japanese Patients with Unilateral Age-Related Macular Degeneration: The Sakai Lutein Study.

    abstract::This prospective randomized double-masked study investigated the effects of 20 mg lutein supplementation with two different capsules (beeswax or glycerol fatty acid esters) for 6 months on the fellow eyes of 39 Japanese patients with unilateral age-related macular degeneration, and assessed the factors associated with...

    journal_title:Scientific reports

    pub_type: 杂志文章,随机对照试验

    doi:10.1038/s41598-020-62483-0

    authors: Sawa M,Shunto T,Nishiyama I,Yokoyama A,Shigeta R,Miura S,Kawasaki R

    更新日期:2020-04-06 00:00:00

  • Myeloid-derived suppressor cells in the patients with liver resection for hepatitis B virus-related hepatocellular carcinoma.

    abstract::Liver resection remains the popular treatment for hepatocellular carcinoma (HCC). The aim of this study was to explore the alteration of immune cells in HCC patients with liver resections. Nineteen patients were included and their peripheral blood samples were taken before and after liver resections for immune-cell an...

    journal_title:Scientific reports

    pub_type: 临床试验,杂志文章

    doi:10.1038/s41598-019-38785-3

    authors: Lee WC,Wang YC,Cheng CH,Wu TH,Lee CF,Wu TJ,Chou HS,Chan KM

    更新日期:2019-02-19 00:00:00

  • New endoscopic procedure for bladder wall closure: results from the porcine model.

    abstract::Upper urinary tract urothelial carcinomas are usually managed by radical nephroureterectomy (RNU), often followed by intravesical chemotherapy to minimize recurrence. Open surgery is the gold standard procedure for RNU, but it associates with high morbidity, and it has been increasingly replaced by minimally invasive ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-54304-w

    authors: Oliveira C,Barros AA,Reis RL,Correia-Pinto J,Lima E

    更新日期:2019-12-10 00:00:00

  • Plasma cell treatment device Plasma-on-Chip: Monitoring plasma-generated reactive species in microwells.

    abstract::We have developed a plasma cell treatment device called Plasma-on-Chip that enables the real-time monitoring of a single cell culture during plasma treatment. The device consists of three parts: 1) microwells for cell culture, 2) a microplasma device for generating reactive oxygen and nitrogen species (RONS) for use i...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep41953

    authors: Oh JS,Kojima S,Sasaki M,Hatta A,Kumagai S

    更新日期:2017-02-08 00:00:00

  • The intertwined metabolism during symbiotic nitrogen fixation elucidated by metabolic modelling.

    abstract::Genome-scale metabolic network models can be used for various analyses including the prediction of metabolic responses to changes in the environment. Legumes are well known for their rhizobial symbiosis that introduces nitrogen into the global nutrient cycle. Here, we describe a fully compartmentalised, mass and charg...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-30884-x

    authors: Pfau T,Christian N,Masakapalli SK,Sweetlove LJ,Poolman MG,Ebenhöh O

    更新日期:2018-08-21 00:00:00