Biological surface properties in extracellular vesicles and their effect on cargo proteins.

abstract：:The 14-3-3-related protein SMG7 plays critical roles in regulation of DNA damage response and nonsense-mediated mRNA decay (NMD). Like 14-3-3, SMG7 engages phosphoserine-dependent protein interactions; however, the precise role of phosphorylation-mediated SMG7 binding remains unknown. Here, we show that DNA damage-ind...

journal_title：Scientific reports

authors： Cowen LE,Luo H,Tang Y

更新日期：2019-09-11 00:00:00

abstract：:Sharp declines in numerous shark populations around the world have generated considerable interest in better understanding and characterising their biology, ecology and critical habitats. The scalloped hammerhead shark (SHS, Sphyrna lewini) is subject to a multitude of natural and anthropogenic threats that are often ...

journal_title：Scientific reports

authors： Marie AD,Miller C,Cawich C,Piovano S,Rico C

更新日期：2017-12-08 00:00:00

abstract：:The mode of action for oncolytic viruses (OVs) in cancer treatment is thought to depend on a direct initial cytotoxic effect against infected tumor cells and subsequent activation of immune cell responses directed against the neoplasm. To study both of these effects in a mouse model of glioblastoma (GBM), we employed ...

journal_title：Scientific reports

authors： Alayo QA,Ito H,Passaro C,Zdioruk M,Mahmoud AB,Grauwet K,Zhang X,Lawler SE,Reardon DA,Goins WF,Fernandez S,Chiocca EA,Nakashima H

更新日期：2020-03-20 00:00:00

abstract：:Topical anesthetics are widely applied in order to relieve the discomfort and anxiety caused by needle insertion and other painful superficial interventions at the oral cavity. So far, there are no commercially available effective topical anesthetic formulations for that purpose, and the most of developments are relat...

journal_title：Scientific reports

authors： Ribeiro LNM,Franz-Montan M,Alcântara ACS,Breitkreitz MC,Castro SR,Guilherme VA,Muniz BV,Rodrigues da Silva GH,de Paula E

更新日期：2020-07-09 00:00:00

abstract：:In the past few years, the meteoric development of hybrid organic-inorganic perovskite solar cells (PSC) astonished the community. The efficiency has already reached the level needed for commercialization; however, the instability hinders its deployment on the market. Here, we report a mechanism to chemically stabiliz...

journal_title：Scientific reports

authors： El-Mellouhi F,Bentria el T,Rashkeev SN,Kais S,Alharbi FH

更新日期：2016-07-26 00:00:00

abstract：:Activated sludge granules and flocs have their inherent advantages and disadvantages for wastewater treatment due to their different characteristics. So far quantitative information on their evaluation is still lacking. This work provides a quantitative and comparative evaluation on the characteristics and pollutant r...

journal_title：Scientific reports

authors： Fang F,Qiao LL,Ni BJ,Cao JS,Yu HQ

更新日期：2017-02-17 00:00:00

abstract：:Rodents are important reservoir hosts of many important zoonotic viruses. The family Picornaviridae contains clinically important pathogens that infect humans and animals, and increasing numbers of rodent picornaviruses have recently been associated with zoonoses. We collected 574 pharyngeal and anal swab specimens fr...

journal_title：Scientific reports

authors： Du J,Lu L,Liu F,Su H,Dong J,Sun L,Zhu Y,Ren X,Yang F,Guo F,Liu Q,Wu Z,Jin Q

更新日期：2016-09-29 00:00:00

abstract：:Schiff-based complexes as a source of cancer chemotherapeutic compounds have been subjected to the variety of anticancer studies. The in-vitro analysis confirmed the CdCl2(C14H21N3O2) complex possess cytotoxicity and apoptosis induction properties in colon cancer cells, so lead to investigate the inhibitory efficiency...

journal_title：Scientific reports

authors： Hajrezaie M,Shams K,Moghadamtousi SZ,Karimian H,Hassandarvish P,Emtyazjoo M,Zahedifard M,Majid NA,Mohd Ali H,Abdulla MA

更新日期：2015-07-23 00:00:00

abstract：:Fragmentation of thin layers of materials is mediated by a network of cracks on its surface. It is commonly seen in dehydrated paintings or asphalt pavements and even in graphene or other two-dimensional materials, but is also observed in the characteristic polygonal pattern on a crocodile's head. Here, we build a sim...

journal_title：Scientific reports

authors： Qin Z,Pugno NM,Buehler MJ

更新日期：2014-05-27 00:00:00

abstract：:Hyperspectral imaging technology is playing an increasingly important role in the fields of food analysis, medicine and biotechnology. To improve the speed of operation and increase the light throughput in a compact equipment structure, a Fourier transform hyperspectral imaging system based on a single-pixel technique...

journal_title：Scientific reports

authors： Jin S,Hui W,Wang Y,Huang K,Shi Q,Ying C,Liu D,Ye Q,Zhou W,Tian J

更新日期：2017-03-24 00:00:00

abstract：:Endogenous K. pneumoniae endophthalmitis (EKE) has a higher incidence among East Asians, and the most common infectious source of EKE is pyogenic liver abscess (PLA). We investigate the risk factors for poor visual outcomes in patients with PLA-related EKE. The retrospective medical records of 104 patients (120 eyes) ...

journal_title：Scientific reports

authors： Chen YH,Li YH,Lin YJ,Chen YP,Wang NK,Chao AN,Liu L,Wu WC,Lai CC,Chen TL,Chen KJ

更新日期：2019-01-31 00:00:00

abstract：:We describe a spin wave modulator - spintronic device aimed to control spin wave propagation by an electric field. The modulator consists of a ferromagnetic film serving as a spin wave bus combined with a synthetic multiferroic comprising piezoelectric and magnetostrictive materials. Its operation is based on the stre...

journal_title：Scientific reports

authors： Balinskiy M,Chavez AC,Barra A,Chiang H,Carman GP,Khitun A

更新日期：2018-07-18 00:00:00

abstract：:In order to clearly understand the intrinsic microwave absorption properties of carbon nanomaterials, we proposed an efficient strategy to synthesize high purity metal-free carbon nanotubes (CNTs) over water-soluble K2CO3 particles through chemical vapor decomposition and water-washing process. The comparison results ...

journal_title：Scientific reports

authors： Qi X,Xu J,Hu Q,Deng Y,Xie R,Jiang Y,Zhong W,Du Y

更新日期：2016-06-21 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Yoshida S,Miyagawa S,Toyofuku T,Fukushima S,Kawamura T,Kawamura A,Kashiyama N,Nakamura Y,Toda K,Sawa Y

更新日期：2020-06-17 00:00:00

abstract：:Developmental neurotoxic compounds impair the developing human nervous system at lower doses than those affecting adults. Standardized test methods for assessing developmental neurotoxicity (DNT) require the use of high numbers of laboratory animals. Here, we use a novel assay that is based on the development of an in...

journal_title：Scientific reports

authors： Bode K,Nolte L,Kamin H,Desens M,Ulmann A,Bergmann GA,Betker P,Reitmeier J,Ripken T,Stern M,Meyer H,Bicker G

更新日期：2020-02-14 00:00:00

abstract：:Choosing an option increases a person's preference for that option. This phenomenon, called choice-based learning (CBL), has been investigated separately in the contexts of internally guided decision-making (IDM, e.g., preference judgment), for which no objectively correct answer exists, and externally guided decision...

journal_title：Scientific reports

authors： Nakao T,Kanayama N,Katahira K,Odani M,Ito Y,Hirata Y,Nasuno R,Ozaki H,Hiramoto R,Miyatani M,Northoff G

更新日期：2016-08-31 00:00:00

abstract：:Glaucoma is a group of progressive optic neuropathies that share common biological and clinical characteristics including irreversible changes to the optic nerve and visual field loss caused by the death of retinal ganglion cells (RGCs). The loss of RGCs manifests as characteristic cupping or optic nerve degeneration,...

journal_title：Scientific reports

authors： Chavali VRM,Haider N,Rathi S,Vrathasha V,Alapati T,He J,Gill K,Nikonov R,Duong TT,McDougald DS,Nikonov S,O'Brien J,Mills JA

更新日期：2020-07-16 00:00:00

abstract：:Hyperdisulfide-constrained peptides are distinguished by their high stability and diverse functions. Thus far, these peptides have been reported from animals only but their occurrence in plants are rare. Here, we report the discovery, synthesis and characterization of a hyperdisulfide-constrained peptides family of ap...

journal_title：Scientific reports

authors： Wong KH,Tan WL,Xiao T,Tam JP

更新日期：2017-07-21 00:00:00

abstract：:miR1444s are functionally significant miRNAs targeting polyphenol oxidase (PPO) genes for cleavage. MIR1444 genes were reported only in Populus trichocarpa. Through the computational analysis of 215 RNA-seq data, four whole genome sequences of Salicaceae species and deep sequencing of six P. trichocarpa small RNA libr...

journal_title：Scientific reports

authors： Wang M,Li C,Lu S

更新日期：2017-01-10 00:00:00

abstract：:Gelatin-methacryloyl (GelMA) is one of the most commonly used photopolymerizable biomaterials in bio-applications. However, GelMA synthesis remains suboptimal, as its reaction parameters have not been fully investigated. The goal of this study is to establish an optimal route for effective and controllable GelMA synth...

journal_title：Scientific reports

authors： Shirahama H,Lee BH,Tan LP,Cho NJ

更新日期：2016-08-09 00:00:00

abstract：:This study evaluated the impact of mechanically stimulated saliva on initial bacterial colonization. Interaction between oral bacteria and both unstimulated and stimulated saliva was examined in vitro by laying labeled bacteria over SDS-PAGE-separated salivary proteins. The effects of chewing on in vivo biofilm, micro...

journal_title：Scientific reports

authors： Inui T,Palmer RJ Jr,Shah N,Li W,Cisar JO,Wu CD

更新日期：2019-08-14 00:00:00

abstract：:From the viewpoint of thermodynamics, the formation of DNA loops and the interaction between them, which are all non-equilibrium processes, result in the change of free energy, affecting gene expression and further cell-to-cell variability as observed experimentally. However, how these processes dissipate free energy ...

journal_title：Scientific reports

authors： Huang L,Liu P,Yuan Z,Zhou T,Yu J

更新日期：2017-10-03 00:00:00

abstract：:Aedes aegypti is the primary vector for transmission of Dengue, Zika and chikungunya viruses. Previously it was shown that Dengue virus infection of the mosquito led to an in increased expression of the odorant binding protein 22 (AeOBP22) within the mosquito salivary gland and that siRNA mediated knockdown of AeOBP22...

journal_title：Scientific reports

authors： Wang J,Murphy EJ,Nix JC,Jones DNM

更新日期：2020-02-24 00:00:00

abstract：:Melamine detection has attracted much attention since the discovery of the damage of melamine to human health. Herein, we have developed a sensitive homogeneous electroanalytical platform for melamine detection, which is relied on the formation of triplex molecular beacon integrated with exonuclease III (Exo III)-medi...

journal_title：Scientific reports

authors： Liu X,Song M,Li F

更新日期：2017-07-03 00:00:00

abstract：:Age and sleep both affect emotional functioning. Since sleep patterns change over the lifespan, we investigated the effects of short sleep and age on empathic responses. In a randomized cross-over experimental design, healthy young and older volunteers (n = 47 aged 20-30 years and n = 39 aged 65-75 years) underwent fu...

journal_title：Scientific reports

authors： Tamm S,Nilsonne G,Schwarz J,Lamm C,Kecklund G,Petrovic P,Fischer H,Åkerstedt T,Lekander M

更新日期：2017-09-25 00:00:00

abstract：:Glial cell-derived neurotrophic factor (GDNF) has shown beneficial effects in models of Parkinson's disease. The mild results observed in the double-blind clinical trial by intraputamenal infusion of recombinant GDNF proteins warrant a search for alternative delivery methods. In this study, we investigated the functio...

journal_title：Scientific reports

authors： Ren Z,Wang J,Wang S,Zou C,Li X,Guan Y,Chen Z,Zhang YA

更新日期：2013-09-27 00:00:00

abstract：:Synchrotron radiation microtomography (SRμCT) is a nominally non-destructive 3D imaging technique which can visualise the internal structures of whole soft tissues. As a multi-stage technique, the cumulative benefits of optimising sample preparation, scanning parameters and signal processing can improve SRμCT imaging ...

journal_title：Scientific reports

authors： Strotton MC,Bodey AJ,Wanelik K,Darrow MC,Medina E,Hobbs C,Rau C,Bradbury EJ

更新日期：2018-08-13 00:00:00

abstract：:The arrival of the Longobards in Northern Italy in 568 CE marked a period of renewed political stability in the Peninsula after the collapse of the Western Roman Empire. The trajectory of the spread of Longobards in Italy across the Alps and into the South is known from many literary sources. However, their mobility a...

journal_title：Scientific reports

authors： Francisci G,Micarelli I,Iacumin P,Castorina F,Di Vincenzo F,Di Matteo M,Giostra C,Manzi G,Tafuri MA

更新日期：2020-07-15 00:00:00

abstract：:Living organisms employ various mechanisms to escape harm. At the cellular level, mobile cells employ movement to avoid harmful chemicals or repellents. The present study is the first to report that cells move away from the site of injury in response to local wounding. When a migrating Dictyostelium cell was locally w...

journal_title：Scientific reports

authors： Pervin MS,Yumura S

更新日期：2019-03-12 00:00:00

abstract：:The current research on cellular heat stress management focuses on the roles of heat shock proteins (HSPs) and the proteostasis network under severe stress conditions. The mild, fever-type stress and the maintenance of membrane homeostasis are less well understood. Herein, we characterized the acute effect of mild, fe...

journal_title：Scientific reports

authors： Peksel B,Gombos I,Péter M,Vigh L Jr,Tiszlavicz Á,Brameshuber M,Balogh G,Schütz GJ,Horváth I,Vigh L,Török Z

更新日期：2017-11-15 00:00:00