Chronic kidney disease attenuates the impact of obesity on quality of life.

abstract：:The flexible conductive-bridging random access memory (CBRAM) device using a Cu/TiW/Ga2O3/Pt stack is fabricated on polyimide substrate with low thermal budget process. The CBRAM devices exhibit good memory-resistance characteristics, such as good memory window (>105), low operation voltage, high endurance (>1.4 × 102...

journal_title：Scientific reports

authors： Gan KJ,Liu PT,Chien TC,Ruan DB,Sze SM

更新日期：2019-10-02 00:00:00

abstract：:Although the search for quantitative trait loci for behaviour remains a considerable challenge, the complicated genetic architecture of quantitative traits is beginning to be understood. The current project utilised heterogeneous stock (HS) male mice (n = 580) to investigate the genetic basis for brain weights, activi...

journal_title：Scientific reports

authors： Janecka M,Marzi SJ,Parsons MJ,Liu L,Paya-Cano JL,Smith RG,Fernandes C,Schalkwyk LC

更新日期：2017-02-01 00:00:00

abstract：:The FGF receptor signaling pathway is recurrently involved in the leukemogenic processes. Oncogenic fusions of FGFR1 with various fusion partners were described in myeloid proliferative neoplasms, and overexpression and mutations of FGFR3 are common in multiple myeloma. In addition, fibroblast growth factors are abund...

journal_title：Scientific reports

authors： Jerchel IS,Hoogkamer AQ,Ariës IM,Boer JM,Besselink NJM,Koudijs MJ,Pieters R,den Boer ML

更新日期：2019-02-12 00:00:00

abstract：:Adolescence is a critical period for the development of higher-order cognitive functions. Unlike in humans, very limited tools are available to assess such cognitive abilities in adolescent rodents. We implemented a modified 5-Choice Serial Reaction Time Task (5CSRTT) to selectively measure attentiveness, impulsivity,...

journal_title：Scientific reports

authors： Ciampoli M,Contarini G,Mereu M,Papaleo F

更新日期：2017-08-30 00:00:00

abstract：:Amyloid precursor protein (APP) intracellular domain (AICD) is a product of APP processing with transcriptional modulation activity, whose overexpression causes various Alzheimer's disease (AD)-related dysfunctions. Here we report that 1-(3',4'-dichloro-2-fluoro[1,1'-biphenyl]-4-yl)-cyclopropanecarboxylic acid) (CHF50...

journal_title：Scientific reports

authors： Branca C,Sarnico I,Ruotolo R,Lanzillotta A,Viscomi AR,Benarese M,Porrini V,Lorenzini L,Calzà L,Imbimbo BP,Ottonello S,Pizzi M

更新日期：2014-04-09 00:00:00

abstract：:Freeze-thaw cycles are predicted to increase in cold temperate regions. The potential influence of the interactions of freeze-thaw cycles and agrochemicals on the release of Cd into river water is unknown. In this study, the interactions of freeze-thaw cycles and chlorpyrifos (FC) on Cd mobility in soils were analysed...

journal_title：Scientific reports

authors： Wang F,Ouyang W,Hao F,Jiao W,Shan Y,Lin C

更新日期：2016-06-02 00:00:00

abstract：:Although macrophages are important players in the injury/repair processes in animal models of acute kidney injury (AKI), their roles in human AKI remains uncertain owing to a paucity of human biopsy studies. We investigated the role of macrophages in 72 cases of biopsy-proven acute tubular necrosis (ATN) and six cases...

journal_title：Scientific reports

authors： Kim MG,Lim K,Lee YJ,Yang J,Oh SW,Cho WY,Jo SK

更新日期：2020-02-07 00:00:00

abstract：:The integral membrane-bound Nrf1 transcription factor fulfils important functions in maintaining cellular homeostasis and organ integrity, but how it is controlled vectorially is unknown. Herein, creative use of Gal4-based reporter assays with protease protection assays (GRAPPA), and double fluorescence protease prote...

journal_title：Scientific reports

authors： Zhang Y,Hayes JD

更新日期：2013-01-01 00:00:00

abstract：:Pseudoalteromonas haloplanktis TAC125 is among the most commonly studied bacteria adapted to cold environments. Aside from its ecological relevance, P. haloplanktis has a potential use for biotechnological applications. Due to its importance, we decided to take advantage of next generation sequencing (Illumina) and th...

journal_title：Scientific reports

authors： Qi W,Colarusso A,Olombrada M,Parrilli E,Patrignani A,Tutino ML,Toll-Riera M

更新日期：2019-11-11 00:00:00

abstract：:Sweet sorghum bagasse (SSB) is a promising raw material for silage fermentation due to its high residual nutritive, but the efficient fermentation strategy of SSB has not been reported yet. This study evaluated the effects of microbial inoculant on the fermentation quality, chemical composition and microbial community...

journal_title：Scientific reports

authors： Dong M,Li Q,Xu F,Wang S,Chen J,Li W

更新日期：2020-01-21 00:00:00

abstract：:Foods and beverage aroma results from multicomponent mixtures of volatile compounds present in the food that interact with olfactory receptors and produce a perceptual response in the brain. However, the perceptual interactions that occur when complex odor mixtures are combined are not well understood. Here we used Ga...

journal_title：Scientific reports

authors： Johnson AJ,Hjelmeland AK,Heymann H,Ebeler SE

更新日期：2019-05-21 00:00:00

abstract：:The zebrafish has the capacity to regenerate its heart after severe injury. While the function of a few genes during this process has been studied, we are far from fully understanding how genes interact to coordinate heart regeneration. To enable systematic insights into this phenomenon, we generated and integrated a ...

journal_title：Scientific reports

authors： Rodius S,Androsova G,Götz L,Liechti R,Crespo I,Merz S,Nazarov PV,de Klein N,Jeanty C,González-Rosa JM,Muller A,Bernardin F,Niclou SP,Vallar L,Mercader N,Ibberson M,Xenarios I,Azuaje F

更新日期：2016-05-31 00:00:00

abstract：:Two hundred and six strains of avian infectious bronchitis virus (IBV) were isolated from chickens showing signs of disease in southern China during the period from 2013-2015. The nucleotide and amino acid sequences from the isolated field strains were compared to 42 published references. Nucleotide homologies ranged ...

journal_title：Scientific reports

authors： Feng K,Wang F,Xue Y,Zhou Q,Chen F,Bi Y,Xie Q

更新日期：2017-07-26 00:00:00

abstract：:The study of cancer immunology has provided diagnostic and therapeutic instruments through serum autoantibody biomarkers and exogenous monoclonal antibodies. While some endogenous antibodies are found within or surrounding transformed tissue, the extent to which this exists has not been entirely characterized. We find...

journal_title：Scientific reports

authors： Rich BS,Honeyman JN,Darcy DG,Smith PT,Williams AR,Lim II,Johnson LK,Gönen M,Simon JS,LaQuaglia MP,Simon SM

更新日期：2014-05-30 00:00:00

abstract：:Many species can successfully colonize new areas despite their propagules having low genetic variation. We assessed whether the decreased genetic diversity could result in temporal fluctuations of genetic parameters of the new populations of an invasive species, western flower thrips, Frankliniella occidentalis, using...

journal_title：Scientific reports

authors： Yang XM,Lou H,Sun JT,Zhu YM,Xue XF,Hong XY

更新日期：2015-07-03 00:00:00

abstract：:The adipogenic process is characterized by the expression of adipocyte differentiation markers that lead to changes in cell metabolism and to the accumulation of lipid droplets. Moreover, during early adipogenesis, cells undergo a strong downregulation of translational activity with a decrease in cell size, proliferat...

journal_title：Scientific reports

authors： Marcon BH,Shigunov P,Spangenberg L,Pereira IT,de Aguiar AM,Amorín R,Rebelatto CK,Correa A,Dallagiovanna B

更新日期：2019-04-04 00:00:00

abstract：:Protein aggregation is a process by which misfolded proteins polymerizes into aggregates and forms fibrous structures with a β-sheet conformation, known as amyloids. It is an undesired outcome, as it not only causes numerous neurodegenerative diseases, but is also a major deterrent in the development of protein biopha...

journal_title：Scientific reports

authors： Rajan R,Matsumura K

更新日期：2017-04-04 00:00:00

abstract：:We evaluated regression of iris neovascularization (INV) using en-face anterior-segment optical coherence tomography angiography (AS-OCTA) after anti-vascular endothelial growth factor (VEGF) therapy. Seven consecutive eyes with INV were examined before and after anti-VEGF therapy, and all AS-OCTA scans were obtained ...

journal_title：Scientific reports

authors： Shiozaki D,Sakimoto S,Shiraki A,Wakabayashi T,Fukushima Y,Oie Y,Usui S,Sato S,Sakaguchi H,Nishida K

更新日期：2019-07-16 00:00:00

abstract：:Regular drusen, an accumulation of material below the retinal pigment epithelium (RPE), have long been established as a hallmark early feature of nonneovascular age-related macular degeneration (AMD). Advances in imaging have expanded the phenotype of AMD to include another extracellular deposit, reticular pseudodruse...

journal_title：Scientific reports

authors： Mishra Z,Ganegoda A,Selicha J,Wang Z,Sadda SR,Hu Z

更新日期：2020-06-12 00:00:00

abstract：:Crossmodal studies have reported not only facilitatory but also inhibitory perceptual interactions. For instance, tactile stimulation to the index finger of a hand leads to the degradation of visual discrimination performance (touch-induced visual suppression, TIVS). It has been suggested that the magnitude of TIVS de...

journal_title：Scientific reports

authors： Hidaka S,Suzuishi Y,Ide M,Wada M

更新日期：2018-11-19 00:00:00

abstract：:Lung cancer represents a major cause of cancer-related death worldwide. Although various tactics and anti-tumor drugs have been used to improve curative effects, five-year survival rate of lung cancer patients remains poor. In this study, we investigated the action and underlying mechanisms of our recently optimized C...

journal_title：Scientific reports

authors： Zheng T,Que Z,Jiao L,Kang Y,Gong Y,Yao J,Ma C,Bi L,Dong Q,Zhao X,Xu L

更新日期：2017-07-10 00:00:00

abstract：:Early diagnosis of dementia including Alzheimer's disease (AD) is an urgent medical and welfare issue. However, to date, no simple biometrics have been available. We reported that blood DNA methylation levels of the COASY gene, which encodes coenzyme A synthase, were increased in individuals with AD and amnestic mild ...

journal_title：Scientific reports

authors： Kobayashi N,Shinagawa S,Niimura H,Kida H,Nagata T,Tagai K,Shimada K,Oka N,Shikimoto R,Noda Y,Nakajima S,Mimura M,Shigeta M,Kondo K

更新日期：2020-07-22 00:00:00

abstract：:microRNAs (miRNAs) are small double stranded RNA molecules consisting of two complementary strands called the 5p and 3p arms. Following imprecise processing and/or addition of nucleotides at the ends, miRNA biogenesis can give rise to variants called isomiRs. Exosomes are small vesicles released by cells. They have at...

journal_title：Scientific reports

authors： Karlsen TA,Aae TF,Brinchmann JE

更新日期：2019-12-27 00:00:00

abstract：:The major human pathogen Mycobacterium tuberculosis is rarely reported to cause disease in other animals. Cases in livestock are thought to occur through contact with infected handlers, but previous studies evaluating putative livestock-human transmission used typing techniques with limited resolution. Here, we undert...

journal_title：Scientific reports

authors： Palaniyandi K,Kumar N,Veerasamy M,Kabir Refaya A,Dolla C,Balaji S,Baskaran D,Thiruvengadam K,Rajendran A,Narayanan S,Raj D,Swaminathan S,Peacock SJ

更新日期：2019-11-29 00:00:00

abstract：:Outcomes following admission to intensive care units (ICU) may vary with time and day. This study investigated associations between time of day and risk of ICU mortality and chance of ICU discharge in acute ICU admissions. Adult patients (age ≥ 18 years) who were admitted to ICUs participating in the Austrian intensiv...

journal_title：Scientific reports

authors： Zajic P,Bauer P,Rhodes A,Moreno R,Fellinger T,Metnitz B,Posch M,Metnitz PGH

更新日期：2019-08-29 00:00:00

abstract：:Two series of Ge0.8Sn0.2 samples were grown on Ge buffered Si substrate by molecular beam epitaxy (MBE) to investigate the influence of growth temperature and film thickness towards the evolution of surface morphology. A novel phenomena was observed that the Ge0.8Sn0.2 film was segregated and relaxed by the formation ...

journal_title：Scientific reports

authors： Wang N,Xue C,Wan F,Zhao Y,Xu G,Liu Z,Zheng J,Zuo Y,Cheng B,Wang Q

更新日期：2020-04-09 00:00:00

abstract：:A p-i-n junction diode based on the selectively doped single-walled carbon nanotube (SWCNT) had been investigated, in which two opposite ends of individual SWCNT channel were doped into the p- and n-type SWCNT respectively while the middle segment of SWCNT was kept as the intrinsic. The symmetric and asymmetric contac...

journal_title：Scientific reports

authors： Chen C,Liao C,Wei L,Zhong H,He R,Liu Q,Liu X,Lai Y,Song C,Jin T,Zhang Y

更新日期：2016-02-26 00:00:00

abstract：:Betaine alleviates high-fat diet-induced fatty liver and prenatal betaine programs offspring hepatic lipid metabolism. Excessive corticosterone (CORT) exposure causes fatty liver in chickens, yet it remains unknown whether and how prenatal betaine modulates the susceptibility of CORT-induced fatty liver later in life....

journal_title：Scientific reports

authors： Hu Y,Sun Q,Liu J,Jia Y,Cai D,Idriss AA,Omer NA,Zhao R

更新日期：2017-01-06 00:00:00

abstract：:Neuromodulation is an increasingly accepted treatment for neurological and psychiatric disorders but is limited by its invasiveness or its inability to target deep brain structures using noninvasive techniques. We propose a new concept called Multimodal Synchronization Therapy (mSync) for achieving targeted activation...

journal_title：Scientific reports

authors： Markovitz CD,Smith BT,Gloeckner CD,Lim HH

更新日期：2015-03-25 00:00:00

abstract：:A high specificity aptamer-ligand biorecognition and binding system to monitor of dexamethasone (DXN) was developed. The detection principle was based on a label-free electrochemical aptasensor. The selection of the aptamer was successfully performed by the systematic evolution of ligands through exponential enrichmen...

journal_title：Scientific reports

authors： Mehennaoui S,Poorahong S,Jimenez GC,Siaj M

更新日期：2019-04-29 00:00:00