The membrane-topogenic vectorial behaviour of Nrf1 controls its post-translational modification and transactivation activity.

abstract：:There is lack of consensus regarding the prognostic significance of primary tumor location of upper tract urothelial carcinoma(UTUC). We performed a meta-analysis to evaluate the impact of primary tumor location on prognosis in patients with UTUC who had undergone radical nephroureterectomy(RNU). We included eligible ...

journal_title：Scientific reports

authors： Wu Y,Dong Q,Liu L,Han P,Wei Q

更新日期：2014-09-15 00:00:00

abstract：:We performed a systematic investigation on the dynamic behavior of conduction filaments (CFs) in WO₃-x-based devices. It was found that the electric forming produced an electric structure consisted of a conductive channel (virtual cathode) started from cathode and an insulating band surrounding anode. Both the virtual...

journal_title：Scientific reports

authors： Hong DS,Chen YS,Li Y,Yang HW,Wei LL,Shen BG,Sun JR

更新日期：2014-02-11 00:00:00

abstract：:The effect on the reproductive system and fertility of living in a space environment remains unclear. Here, we caged 12 male mice under artificial gravity (≈1 gravity) (AG) or microgravity (MG) in the International Space Station (ISS) for 35 days, and characterized the male reproductive organs (testes, epididymides, a...

journal_title：Scientific reports

authors： Matsumura T,Noda T,Muratani M,Okada R,Yamane M,Isotani A,Kudo T,Takahashi S,Ikawa M

更新日期：2019-09-24 00:00:00

abstract：:Mesenchymal stem cells (MSCs) are highly plastic cells that are able to transdifferentiate or dedifferentiate under appropriate conditions. In the present study, we reported here that after in vitro induction of osteogenic differentiation, MSCs could be reverted to a primitive stem cell population (dedifferentiated os...

journal_title：Scientific reports

authors： Rui Y,Xu L,Chen R,Zhang T,Lin S,Hou Y,Liu Y,Meng F,Liu Z,Ni M,Tsang KS,Yang F,Wang C,Chan HC,Jiang X,Li G

更新日期：2015-06-08 00:00:00

abstract：:Copy Number Variants (CNVs) are a class of structural variations of DNA. Germline CNVs are known to confer disease susceptibility, but their role in breast cancer warrants further investigations. We hypothesized that breast cancer associated germline CNVs contribute to disease risk through gene dosage or other post-tr...

journal_title：Scientific reports

authors： Kumaran M,Krishnan P,Cass CE,Hubaux R,Lam W,Yasui Y,Damaraju S

更新日期：2018-05-14 00:00:00

abstract：:In order to design a painless and mechanically durable micro syringe-needle system for biomedical applications, the study of insect stingers is of interest because of their elegant structures and functionalities. In the present work, the structure, mechanical properties and the mechanical behavior during insertion of ...

journal_title：Scientific reports

authors： Das R,Yadav RN,Sihota P,Uniyal P,Kumar N,Bhushan B

更新日期：2018-10-08 00:00:00

abstract：:Gold nanoparticles (GNP) have been intensively investigated for applications in cancer imaging and therapy. Most imaging studies focused on microscopic imaging. Their potential as optical imaging probes for whole body small animal imaging has rarely been explored. Taking advantage of their surface plasmon resonance (S...

journal_title：Scientific reports

authors： Xu K,Shi J,Pourmand A,Udayakumar TS,Dogan N,Zhao W,Pollack A,Yang Y

更新日期：2018-06-19 00:00:00

abstract：:Colon cancer stem cells have been attributed to poor prognosis, therapeutic resistance and aggressive nature of the malignancy. Recent reports associated CD44v6 expression with relapse, metastasis and reduced 5-year survival of colon cancer patients, thereby making it a potential therapeutic target. Thus, in this stud...

journal_title：Scientific reports

authors： Patel S,Waghela B,Shah K,Vaidya F,Mirza S,Patel S,Pathak C,Rawal R

更新日期：2018-11-19 00:00:00

abstract：:FcRn mediates recycling and transcytosis of IgG and albumin in various cell types. The MHC-class-I-like protein of the FcRn heterodimer is encoded by FCGRT. Few determinants of variable FCGRT expression in humans have been identified so far. In this study, we investigated the presence of DNA methylation in regulatory ...

journal_title：Scientific reports

authors： Cejas RB,Ferguson DC,Quiñones-Lombraña A,Bard JE,Blanco JG

更新日期：2019-06-17 00:00:00

abstract：:Although geological and modelling evidence indicate that the last glacial inception in North America was in NE Canada, little is known about the glacial response of the nearby western Greenland Ice Sheet (GIS) during the glacial advance of marine oxygen isotope stage 4 (MIS4). Our multi-proxy study of a marine sedimen...

journal_title：Scientific reports

authors： Seidenkrantz MS,Kuijpers A,Olsen J,Pearce C,Lindblom S,Ploug J,Przybyło P,Snowball I

更新日期：2019-10-30 00:00:00

abstract：:Five different weed plants viz. Convulvulus arvensis, Chenopodium murale, Tribulus terrestris, Trianthema portulacastrum, and Achyranthes aspera were investigated for their entomocidal and genotoxic effects against Culex quinquefasciatus mosquitoes. High mortality was observed at 72 hours in a dose dependent manner. A...

journal_title：Scientific reports

authors： Zulhussnain M,Zahoor MK,Rizvi H,Zahoor MA,Rasul A,Ahmad A,Majeed HN,Rasul A,Ranian K,Jabeen F

更新日期：2020-04-22 00:00:00

abstract：:The effect of annealing both in the oxygen atmosphere and at room temperatures on physical properties such as the pseudogap (Δ*(T)) and excess conductivity (σ'(T)) of untwined YBa2Cu3O7-δ (YBCO) single crystal with a small deviation from oxygen stoichiometry is studied. It was revealed that as the charge carrier densi...

journal_title：Scientific reports

authors： Solovjov AL,Petrenko EV,Omelchenko LV,Vovk RV,Goulatis IL,Chroneos A

更新日期：2019-06-25 00:00:00

abstract：:To better understand the effects of transient thermal stress in an aquatic insect, we first identified static temperatures associated with fitness deficits, and then reared larvae from egg hatch to adulthood under diurnally variable regimens including daily forays into deleterious temperatures. We sampled mature larva...

journal_title：Scientific reports

authors： Chou H,Jima DD,Funk DH,Jackson JK,Sweeney BW,Buchwalter DB

更新日期：2020-11-05 00:00:00

abstract：:Cladosporium cladosporioides causes asthma and superficial and deep infections, mostly in immunodeficient individuals and animals. This study aimed to investigate whether C. cladosporioides spores can enter the lungs through pulmonary circulation and influence pulmonary immune response. We intravenously injected mice ...

journal_title：Scientific reports

authors： Ma X,Hu J,Yu Y,Wang C,Gu Y,Cao S,Huang X,Wen Y,Zhao Q,Wu R,Zuo Z,Deng J,Ren Z,Yu S,Shen L,Zhong Z,Peng G

更新日期：2021-01-13 00:00:00

abstract：:Brain trauma was clinically associated with increased osteogenesis in the appendicular skeleton. We showed previously in C57BL/6J mice that mild traumatic brain injury (mTBI) transiently induced bone formation in the femur via the cannabinoid-1 (CB1) receptor. Here, we subjected ICR mice to mTBI and examined the bone ...

journal_title：Scientific reports

authors： Eger M,Bader M,Bree D,Hadar R,Nemirovski A,Tam J,Levy D,Pick CG,Gabet Y

更新日期：2019-11-07 00:00:00

abstract：:Bagging is an efficient method to improve fruit colour development. This work reported a transcriptome analysis using bagging-treated red Chinese sand pear peels. In total, 8,870 differentially expressed genes were further analysed by a weighted gene co-expression network analysis and early-, middle- and late light-re...

journal_title：Scientific reports

authors： Bai S,Sun Y,Qian M,Yang F,Ni J,Tao R,Li L,Shu Q,Zhang D,Teng Y

更新日期：2017-03-03 00:00:00

abstract：:Anatomical features of first maxillary premolars may greatly affect endodontic and following restorative treatments. The aim of this study was to evaluate root canal configuration and root wall thickness of first maxillary premolars using a preexisting CBCT database. A CBCT database of 400 first maxillary premolar was...

journal_title：Scientific reports

authors： Kfir A,Mostinsky O,Elyzur O,Hertzeanu M,Metzger Z,Pawar AM

更新日期：2020-01-16 00:00:00

abstract：:Climate change significantly impacts the vegetation growth and terrestrial ecosystems. Using satellite remote sensing observations, here we focus on investigating vegetation dynamics and the likelihood of vegetation-related drought under varying climate conditions across China. We first compare temporal trends of Norm...

journal_title：Scientific reports

authors： Liu Z,Li C,Zhou P,Chen X

更新日期：2016-10-07 00:00:00

abstract：:Integrin α11β1 is a collagen-binding integrin, which is receiving increasing attention in the context of wound healing and fibrosis. Although α11β1 integrin displays similar collagen specificity to α2β1 integrin, both integrins have distinct in vivo functions. In this context, the contribution of α11 subunit cytoplasm...

journal_title：Scientific reports

authors： Erusappan P,Alam J,Lu N,Zeltz C,Gullberg D

更新日期：2019-10-25 00:00:00

abstract：:Although optimal therapy for myocardial infarction includes reperfusion to restore blood flow to the ischemic region, ischemia/reperfusion (IR) also initiates an inflammatory response likely contributing to adverse left ventricular (LV) extracellular matrix (ECM) remodeling. Galectin-3 (Gal-3), a β-galactoside-binding...

journal_title：Scientific reports

authors： Ibarrola J,Matilla L,Martínez-Martínez E,Gueret A,Fernández-Celis A,Henry JP,Nicol L,Jaisser F,Mulder P,Ouvrard-Pascaud A,López-Andrés N

更新日期：2019-07-03 00:00:00

abstract：:Allicin (diallylthiosulfinate) is a defence molecule from garlic (Allium sativum L.) with broad antimicrobial activities in the low µM range against Gram-positive and -negative bacteria, including antibiotic resistant strains, and fungi. Allicin reacts with thiol groups and can inactivate essential enzymes. However, a...

journal_title：Scientific reports

authors： Leontiev R,Hohaus N,Jacob C,Gruhlke MCH,Slusarenko AJ

更新日期：2018-04-30 00:00:00

abstract：:During spring of 2009, a new influenza virus AH1N1 spread in the world causing acute respiratory illness and death, resulting in the first influenza pandemic since 1968. Blood levels of potentially-toxic and essential elements of 40 pneumonia and confirmed AH1N1 were evaluated against two different groups of controls,...

journal_title：Scientific reports

authors： Moya M,Bautista EG,Velázquez-González A,Vázquez-Gutiérrez F,Tzintzun G,García-Arreola ME,Castillejos M,Hernández A

更新日期：2013-01-01 00:00:00

abstract：:Genotyping-by-sequencing (GBS) or restriction-site associated DNA marker sequencing (RAD-seq) is a practical and cost-effective method for analysing large genomes from high diversity species. This method of sequencing, coupled with methylation-sensitive enzymes (often referred to as methylation-sensitive restriction e...

journal_title：Scientific reports

authors： Mayne BT,Leemaqz SY,Buckberry S,Rodriguez Lopez CM,Roberts CT,Bianco-Miotto T,Breen J

更新日期：2018-02-01 00:00:00

abstract：:The spinal cord is an integration center for descending, ascending, and segmental neural signals. Noninvasive transspinal stimulation may thus constitute an effective method for concomitant modulation of local and distal neural circuits. In this study, we established changes in cortical excitability and input/output f...

journal_title：Scientific reports

authors： Murray LM,Tahayori B,Knikou M

更新日期：2018-01-15 00:00:00

abstract：:Asthma is characterized by airway inflammation, mucus secretion, remodeling and hyperresponsiveness (AHR). Recent research has established the bronchodilatory effect of bitter taste receptor (TAS2R) agonists in various models. Comprehensive pre-clinical studies aimed at establishing effectiveness of TAS2R agonists in ...

journal_title：Scientific reports

authors： Sharma P,Yi R,Nayak AP,Wang N,Tang F,Knight MJ,Pan S,Oliver B,Deshpande DA

更新日期：2017-04-11 00:00:00

abstract：:We have engineered the electronic structure at the interface between Cu2O and ZnO nanorods (NRs) array, through adjusting the carrier concentration of Cu2O. The electrodeposition of Cu2O at pH 11 acquired the highest carrier concentration, resulting in the largest interfacial electric field between Cu2O and ZnO, which...

journal_title：Scientific reports

authors： Kang Z,Yan X,Wang Y,Bai Z,Liu Y,Zhang Z,Lin P,Zhang X,Yuan H,Zhang X,Zhang Y

更新日期：2015-01-20 00:00:00

abstract：:Asymmetric cell division is a ubiquitous feature during the development of higher organisms. Asymmetry is achieved by differential localization or activities of biological molecules such as proteins, and coding and non-coding RNAs. Here, we present subcellular transcriptomic and proteomic analyses along the animal-veg...

journal_title：Scientific reports

authors： Sindelka R,Abaffy P,Qu Y,Tomankova S,Sidova M,Naraine R,Kolar M,Peuchen E,Sun L,Dovichi N,Kubista M

更新日期：2018-05-29 00:00:00

abstract：:The Raman spectral features from spinal cord tissue sections of transgenic, ALS model mice and non-transgenic mice were compared using 457 nm excitation line, profiting from the favourable signal intensity obtained in the molecular fingerprint region at this wavelength. Transverse sections from four SOD1G93A mice at 7...

journal_title：Scientific reports

authors： Picardi G,Spalloni A,Generosi A,Paci B,Mercuri NB,Luce M,Longone P,Cricenti A

更新日期：2018-08-30 00:00:00

abstract：:CHF5633 is a novel synthetic clinical pulmonary surfactant preparation composed by two phospholipid species, dipalmitoyl phosphatidylcholine (DPPC) and palmitoyloleoyl phosphatidylglycerol (POPG), and synthetic analogues of the hydrophobic surfactant proteins SP-B and SP-C. In this study, the interfacial properties of...

journal_title：Scientific reports

authors： Echaide M,Autilio C,López-Rodríguez E,Cruz A,Pérez-Gil J

更新日期：2020-01-28 00:00:00

abstract：:Range-wide population studies of wide spread species are often associated with complex diversity patterns resulting from genetically divergent evolutionary significant units (ESUs). The compound evolutionary history creating such a pattern of diversity can be inferred through molecular analyses. Asparagus cochinchinen...

journal_title：Scientific reports

authors： Lee SR,Park HS,Kim BY,Lee JH,Fan Q,Gaskin JF,Kim YD

更新日期：2019-07-05 00:00:00