Analysis of the dynamic co-expression network of heart regeneration in the zebrafish.

abstract：:Metallo-β-lactamases (MBLs) are a group of enzymes that can inactivate most commonly used β-lactam-based antibiotics. Among MBLs, New Delhi metallo-β-lactamase-1 (NDM-1) constitutes an urgent threat to public health as evidenced by its success in rapidly disseminating worldwide since its first discovery. Here we repor...

journal_title：Scientific reports

authors： Jiang XW,Cheng H,Huo YY,Xu L,Wu YH,Liu WH,Tao FF,Cui XJ,Zheng BW

更新日期：2018-01-16 00:00:00

abstract：:EhV-ATPase is an ATP-driven Na+ pump in the eubacteria Enterococcus hirae (Eh). Here, we present the first entire structure of detergent-solubilized EhV-ATPase by single-particle cryo-electron microscopy (cryo-EM) using Zernike phase plate. The cryo-EM map dominantly showed one of three catalytic conformations in this...

journal_title：Scientific reports

authors： Tsunoda J,Song C,Imai FL,Takagi J,Ueno H,Murata T,Iino R,Murata K

更新日期：2018-10-23 00:00:00

abstract：:Genome-wide DNA methylation and gene expression are commonly altered in pediatric acute lymphoblastic leukemia (PALL). Integrated network analysis of cytosine methylation and expression datasets has the potential to provide deeper insights into the complex disease states and their causes than individual disconnected a...

journal_title：Scientific reports

authors： Sanchez R,Mackenzie SA

更新日期：2020-02-07 00:00:00

abstract：:Synovial fibroblasts (SF) were reported to produce B cell activating factor (BAFF) in response to stimulation with interferon-γ (IFN-γ) or tumor necrosis factor (TNF). However, the influence of these pro-inflammatory cytokines on other receptors/ligands of the TNF superfamily or associated cytokine receptors in SF has...

journal_title：Scientific reports

authors： Lowin T,Anssar TM,Bäuml M,Classen T,Schneider M,Pongratz G

更新日期：2020-01-21 00:00:00

abstract：:Post-transcriptional gene regulation by microRNAs (miRNAs) is involved in memory formation. However, the roles of individual miRNAs in these processes remain largely unknown. In this study, we want to clarify the role of miR-181a in hippocampus-dependent memory formation. A transient increase in miR-181a expression wa...

journal_title：Scientific reports

authors： Zhang SF,Chen JC,Zhang J,Xu JG

更新日期：2017-08-16 00:00:00

abstract：:Phomopsis sp. XP-8, an endophytic fungus from the bark of Tu-Chung (Eucommia ulmoides Oliv) showed capability to biosynthesize pinoresinol (Pin) and pinoresinol diglucoside (PDG) from glucose (glu) and phenylalanine (Phe). To verify the mass flow in the biosynthesis pathway, [13C6]-labeled glu and [13C6]-labeled Phe w...

journal_title：Scientific reports

authors： Zhang Y,Shi J,Ni Y,Liu Y,Zhao Z,Zhao X,Gao Z

更新日期：2019-12-06 00:00:00

abstract：:Helicobacter pylori (H. pylori ) infection is a major cause of chronic gastritis and is highly related to duodenal ulcer (DU) and gastric cancer (GC). To identify H. pylori-related GC biomarkers with high seropositivity in GC patients, differences in levels of protein expression between H. pylori from GC and DU patien...

journal_title：Scientific reports

authors： Su YL,Huang HL,Huang BS,Chen PC,Chen CS,Wang HL,Lin PH,Chieh MS,Wu JJ,Yang JC,Chow LP

更新日期：2016-11-07 00:00:00

abstract：:Seagrass meadows are threatened by coastal development and global change. In the face of these pressures, molecular techniques such as reverse transcription quantitative real-time PCR (RT-qPCR) have great potential to improve management of these ecosystems by allowing early detection of chronic stress. In RT-qPCR, the...

journal_title：Scientific reports

authors： Schliep M,Pernice M,Sinutok S,Bryant CV,York PH,Rasheed MA,Ralph PJ

更新日期：2015-11-23 00:00:00

abstract：:Natural history collections are often plagued by missing or inaccurate metadata for collection items, particularly for specimens that are difficult to verify or rare. Avian eggshell in particular can be challenging to identify due to extensive morphological ambiguity among taxa. Species identifications can be improved...

journal_title：Scientific reports

authors： Grealy A,Langmore NE,Joseph L,Holleley CE

更新日期：2021-01-15 00:00:00

abstract：:Neural networks can efficiently encode the probability distribution of errors in an error correcting code. Moreover, these distributions can be conditioned on the syndromes of the corresponding errors. This paves a path forward for a decoder that employs a neural network to calculate the conditional distribution, then...

journal_title：Scientific reports

authors： Krastanov S,Jiang L

更新日期：2017-09-08 00:00:00

abstract：:The salmon louse is an ectoparasitic copepod of salmonids in the marine environment, and represents a global challenge to salmon aquaculture. A major issue is the reliance of the industry on a limited number of chemicals to delouse salmonids on farms, and the high levels of resistance that lice have developed to all o...

journal_title：Scientific reports

authors： Kaur K,Besnier F,Glover KA,Nilsen F,Aspehaug VT,Fjørtoft HB,Horsberg TE

更新日期：2017-09-27 00:00:00

abstract：:Converging evidence has proved the attentional bias of Internet addicts (IAs) on network information. However, previous studies have neither explained how characteristics of network information are detected by IAs with priority nor proved whether this advantage is in line with the unconscious and automatic process. To...

journal_title：Scientific reports

authors： He J,Zheng Y,Nie Y,Zhou Z

更新日期：2018-06-12 00:00:00

abstract：:Hormones and placental factors are thought to underlie the maternal immunological changes during pregnancy. However, as several intestinal microbiota are linked to immune modulations, we hypothesized that the intestinal microbiota are altered during pregnancy in favor of species associated with pregnancy associated im...

journal_title：Scientific reports

authors： Elderman M,Hugenholtz F,Belzer C,Boekschoten M,de Haan B,de Vos P,Faas M

更新日期：2018-07-03 00:00:00

abstract：:Knockdown and mortality of adults of the red flour beetle, Tribolium castaneum (Herbst) and the confused flour beetle, Tribolium confusum Jacquelin du Val, were assessed after exposure to two contact insecticides, chlorfenapyr and cyfluthrin, on a concrete surface. Individuals were rated on a scale for knockdown of ex...

journal_title：Scientific reports

authors： Athanassiou CG,Kavallieratos NG,Arthur FH,Nakas CT

更新日期：2021-01-13 00:00:00

abstract：:One of the health hazards of PM2.5 exposure is to induce pulmonary inflammatory responses. In our previous study, we demonstrated that exposing both the immortalized and primary human bronchial epithelial cells to PM2.5 results in a significant upregulation of VEGF production, a typical signaling event to trigger chro...

journal_title：Scientific reports

authors： Xu H,Xu X,Wang H,Qimuge A,Liu S,Chen Y,Zhang C,Hu M,Song L

更新日期：2019-11-12 00:00:00

abstract：:The spread of multidrug resistance via mobile genetic elements is a major clinical and veterinary concern. Pathogenic Escherichia coli harbour antibiotic resistance and virulence genes mainly on plasmids, but also bacteriophages and hybrid phage-like plasmids. In this study, the genomes of three E. coli phage-like pla...

journal_title：Scientific reports

authors： Venturini C,Zingali T,Wyrsch ER,Bowring B,Iredell J,Partridge SR,Djordjevic SP

更新日期：2019-12-11 00:00:00

abstract：:The Pyrrolysyl-tRNA synthetase (PylRS) and its cognate tRNAPyl are extensively used to add non-canonical amino acids (ncAAs) to the genetic code of bacterial and eukaryotic cells. However, new ncAAs often require a cumbersome de novo engineering process to generate an appropriate PylRS/tRNAPyl pair. We here report a s...

journal_title：Scientific reports

authors： Hohl A,Karan R,Akal A,Renn D,Liu X,Ghorpade S,Groll M,Rueping M,Eppinger J

更新日期：2019-08-19 00:00:00

abstract：:In this study, we categorize the microbial community in mangrove sediment samples from four different locations within a vast mangrove system in Kerala, India. We compared this data to other samples taken from the other known mangrove data, a tropical rainforest, and ocean sediment. An examination of the microbial com...

journal_title：Scientific reports

authors： Imchen M,Kumavath R,Barh D,Azevedo V,Ghosh P,Viana M,Wattam AR

更新日期：2017-08-18 00:00:00

abstract：:The majority of individuals with Down syndrome (DS) do not exhibit accurate accommodation, with the aetiology of this deficit unknown. This study examines the mechanism underlying hypoaccommodation in DS by simultaneously investigating the 'near triad' - accommodation, vergence and pupillary response. An objective pho...

journal_title：Scientific reports

authors： Doyle L,Saunders KJ,Little JA

更新日期：2016-02-05 00:00:00

abstract：:We propose a polarization beam splitter (PBS) with a footprint of only 600 × 790 nm2 operating at a wavelength of λ = 1550 nm, which is the smallest PBS ever demonstrated. This device uses CMOS-compatible materials, namely, silicon and silica. The present PBS comprises two Si waveguides with different geometrical aspe...

journal_title：Scientific reports

authors： Lai MS,Huang CC

更新日期：2017-07-03 00:00:00

abstract：:Endovascular methods have been increasingly applied in treating cervicocranial artery dissection (CCAD). Anti-thrombotic therapy, which is used in non-interventional care of CCAD patients, has differential effects in East Asian patients. Therefore, we aimed to compare the clinical outcomes of endovascular versus non-i...

journal_title：Scientific reports

authors： Huang R,Niu L,Wang Y,Jia G,Jia L,Wang Y,Jiang W,Sun Y,Yu L

更新日期：2015-05-20 00:00:00

abstract：:Targeting myeloid differentiation protein 2 (MD-2) or Toll-like receptor 4 (TLR4) with small molecule inhibitor rescues the systemic inflammatory response syndrome (SIRS) in sepsis due to infection with Gram-negative bacteria but not other microbes. Herein, we provided IκB kinase β (IKKβ) in innate immune process as a...

journal_title：Scientific reports

authors： Choi JH,Park SH,Jung JK,Cho WJ,Ahn B,Yun CY,Choi YP,Yeo JH,Lee H,Hong JT,Han SB,Kim Y

更新日期：2017-02-01 00:00:00

abstract：:A role of gut-brain axis emerges in the pathophysiology of anorexia nervosa and maintaining adapted physical activity during refeeding remains discussed. We aimed to assess gastrointestinal protein metabolism and investigate the contribution of physical activity during refeeding in C57BL/6 mice with activity-based ano...

journal_title：Scientific reports

authors： Achamrah N,Nobis S,Breton J,Jésus P,Belmonte L,Maurer B,Legrand R,Bôle-Feysot C,do Rego JL,Goichon A,Rego JC,Déchelotte P,Fetissov SO,Claeyssens S,Coëffier M

更新日期：2016-02-24 00:00:00

abstract：:Some neural network can be trained by transfer learning, which uses a pre-trained neural network as the source task, for a small target task's dataset. The performance of the transfer learning depends on the knowledge (i.e., layers) selected from the pre-trained network. At present, this knowledge is usually chosen by...

journal_title：Scientific reports

authors： Imai S,Kawai S,Nobuhara H

更新日期：2020-05-18 00:00:00

abstract：:Studies of personality have suggested that dissimilarities in ability to cope with stressful situations results in differing tendency to develop addictive behaviors. The present study used selectively bred stress-resilient, socially-dominant (Dom) and stress-vulnerable, socially-submissive (Sub) mice to investigate th...

journal_title：Scientific reports

authors： Yanovich C,Kirby ML,Michaelevski I,Yadid G,Pinhasov A

更新日期：2018-01-29 00:00:00

abstract：:Anoectochilus roxburghii and Anoectochilus formasanus are the major species of genus Anoectochilus used in traditional Chinese medicine for their abundant content of flavonoids and some other medicinal constituents. In recent years, their wild resources are gradually exhausted due to over-collection and ecological det...

journal_title：Scientific reports

authors： Yang L,Zhang JC,Qu JT,He G,Yu HQ,Li WC,Fu FL

更新日期：2019-12-27 00:00:00

abstract：:The recent rise of multidrug resistant microbial strains requires development of new and novel therapeutic alternatives. In this study, we present a novel antibacterial system that comprises of modified naturally abundant antimicrobial peptides in conjugation with silver nanoparticles. Further, we propose a simple rou...

journal_title：Scientific reports

authors： Pal I,Bhattacharyya D,Kar RK,Zarena D,Bhunia A,Atreya HS

更新日期：2019-03-14 00:00:00

abstract：:Although optimal therapy for myocardial infarction includes reperfusion to restore blood flow to the ischemic region, ischemia/reperfusion (IR) also initiates an inflammatory response likely contributing to adverse left ventricular (LV) extracellular matrix (ECM) remodeling. Galectin-3 (Gal-3), a β-galactoside-binding...

journal_title：Scientific reports

authors： Ibarrola J,Matilla L,Martínez-Martínez E,Gueret A,Fernández-Celis A,Henry JP,Nicol L,Jaisser F,Mulder P,Ouvrard-Pascaud A,López-Andrés N

更新日期：2019-07-03 00:00:00

abstract：:Recently, there has been increasing interest in strategies to predict neurological recovery in cervical myelopathy (CM) based on clinical images of the cervical spine. In this study, we aimed to explore potential preoperative brain biomarkers that can predict postoperative neurological recovery in CM patients by using...

journal_title：Scientific reports

authors： Takenaka S,Kan S,Seymour B,Makino T,Sakai Y,Kushioka J,Tanaka H,Watanabe Y,Shibata M,Yoshikawa H,Kaito T

更新日期：2019-07-18 00:00:00

abstract：:Flubendiamide (FD), the first commercial phthalic acid diamide that targets insect ryanodine receptor (RyRs), has played an important role in pest management. With its extensive worldwide application, a rapid and convenient method to detect its existence in the environment is necessary. In this study, an indirect comp...

journal_title：Scientific reports

authors： Li Q,Cui Y,Liao M,Feng T,Tan G,Wang B,Liu S

更新日期：2019-02-14 00:00:00