Constructive approach for synthesis of a functional IgG using a reconstituted cell-free protein synthesis system.

abstract：:Critical limb ischemia (CLI) is associated with a high risk of limb amputation. It has been shown that cell therapy is safe and has beneficial effects on ischemic clinical symptoms in patients with CLI. The aim of this study was to further investigate the outcomes of intramuscular injection of autologous bone-marrow m...

journal_title：Scientific reports

authors： Yusoff FM,Kajikawa M,Matsui S,Hashimoto H,Kishimoto S,Maruhashi T,Chowdhury M,Noma K,Nakashima A,Kihara Y,Sueda T,Higashi Y

更新日期：2019-05-22 00:00:00

abstract：:Adolescent idiopathic scoliosis (AIS) patients have been reported to be taller and more slender than normal controls, suggesting less mechanical stiffness of their trunk and spine. For assessment of mechanical stiffness, to our best knowledge this is the first to study height-width-depth relations at the level of the ...

journal_title：Scientific reports

authors： Chen H,Schlösser TPC,Brink RC,Colo D,van Stralen M,Shi L,Chu WCW,Heng PA,Castelein RM,Cheng JCY

更新日期：2017-04-18 00:00:00

abstract：:Inflammation is considered as a major contributor to brain injury following cerebral ischemia. The therapeutic potential of both MLC601/MLC901, which are herbal extract preparations derived from Chinese Medicine, has been reported both in advanced stroke clinical trials and also in animal and cellular models. The aim ...

journal_title：Scientific reports

authors： Widmann C,Gandin C,Petit-Paitel A,Lazdunski M,Heurteaux C

更新日期：2018-12-24 00:00:00

abstract：:Adherence to norms and interventions to norm violations are two important forms of social behaviour modelled in economic games. While both appear to serve a prosocial function, they may represent separate mechanisms corresponding with distinct emotional and psychological antecedents, and thus may be predicted by diffe...

journal_title：Scientific reports

authors： Zhao K,Ferguson E,Smillie LD

更新日期：2017-06-13 00:00:00

abstract：:This study was conducted to identify risk factors associated with AIV infections in live bird retail stalls (LBRS) in Lahore District, Pakistan. A cross-sectional survey of LBRS was conducted from December 2009-February 2010 using two-stage cluster sampling based on probability proportional to size. A total of 280 oro...

journal_title：Scientific reports

authors： Chaudhry M,Rashid HB,Angot A,Thrusfield M,Bronsvoort BMD,Capua I,Cattoli G,Welburn SC,Eisler MC

更新日期：2018-04-04 00:00:00

abstract：:Graphene quantum dots (GQDs) have received much attention due to their novel phenomena of charge transport and light absorption/emission. The optical transitions are known to be available up to ~6 eV in GQDs, especially useful for ultraviolet (UV) photodetectors (PDs). Thus, the demonstration of photodetection gain wi...

journal_title：Scientific reports

authors： Kim CO,Hwang SW,Kim S,Shin DH,Kang SS,Kim JM,Jang CW,Kim JH,Lee KW,Choi SH,Hwang E

更新日期：2014-07-07 00:00:00

abstract：:Oxidative stress plays a role in the progression of chronic heart failure (CHF). We investigated whether systemic oxidative stress is linked to exercise intolerance and skeletal muscle abnormalities in patients with CHF. We recruited 30 males: 17 CHF patients, 13 healthy controls. All participants underwent blood test...

journal_title：Scientific reports

authors： Yokota T,Kinugawa S,Hirabayashi K,Yamato M,Takada S,Suga T,Nakano I,Fukushima A,Matsushima S,Okita K,Tsutsui H

更新日期：2021-01-26 00:00:00

abstract：:A universal technology for the encapsulative protection of unstable anionic species by highly stable layered metal oxide has been developed via the surface modification of a metal oxide nanosheet. The surface anchoring of (3-aminopropyl)triethoxysilane (APTES) on exfoliated titanate nanosheet yields a novel cationic m...

journal_title：Scientific reports

authors： Kim TW,Kim IY,Park DH,Choy JH,Hwang SJ

更新日期：2016-02-24 00:00:00

abstract：:There is significant interest in understanding the pathophysiology of Obsessive-Compulsive Disorder (OCD) using resting-state fMRI (rsfMRI). Previous studies acknowledge abnormalities within and beyond the fronto-striato-limbic circuit in OCD that require further clarifications. However, limited information could be i...

journal_title：Scientific reports

authors： Kashyap R,Eng GK,Bhattacharjee S,Gupta B,Ho R,Ho CSH,Zhang M,Mahendran R,Sim K,Chen SHA

更新日期：2021-01-14 00:00:00

abstract：:Chloroquine (CQ) and hydroxychloroquine, are promising anti-inflammatory drugs for the treatment of Diabetes mellitus (DM) to prevent associated complications. Therefore, this study evaluated the anti-inflammatory effects of CQ-free and CQ-incorporated polylactic acid nanoparticles (NPs) in the peripheral blood mononu...

journal_title：Scientific reports

authors： de Almeida Júnior RF,de Souza KSC,Galdino OA,da Silva Junior AA,Arrais RF,Machado PRL,Farias KJS,de Rezende AA

更新日期：2020-07-21 00:00:00

abstract：:Micro- and nanoscale surface textures, when optimally designed, present a unique approach to improve surface functionalities. Coupling surface texture with shape memory polymers may generate reversibly tuneable surface properties. A shape memory polyetherurethane is used to prepare various surface textures including 2...

journal_title：Scientific reports

authors： Lee WL,Low HY

更新日期：2016-03-30 00:00:00

abstract：:Type 2 diabetes (T2D) is emerging as one of the serious public health issues in both developed and developing counties. Here, we surveyed the worldwide population differentiation in T2D-associated variants and assessed the genetic burden of the disease in an ongoing Tehran Cardio-Metabolic Genetic Study (TCGS) cohort ...

journal_title：Scientific reports

authors： Moazzam-Jazi M,Najd Hassan Bonab L,Zahedi AS,Daneshpour MS

更新日期：2020-08-19 00:00:00

abstract：:Osteolineage cells represent one of the critical bone marrow niche components that support maintenance of hematopoietic stem and progenitor cells (HSPCs). Recent studies demonstrate that extracellular vesicles (EVs) regulate stem cell development via horizontal transfer of bioactive cargo, including microRNAs (miRNAs)...

journal_title：Scientific reports

authors： Morhayim J,van de Peppel J,Braakman E,Rombouts EW,Ter Borg MN,Dudakovic A,Chiba H,van der Eerden BC,Raaijmakers MH,van Wijnen AJ,Cornelissen JJ,van Leeuwen JP

更新日期：2016-09-02 00:00:00

abstract：:A great deal of attention has been recently focused on Electrochromic (EC) materials and EC based devices, promoting mainly applications related to display technology. In this case, EC based displays are usually actuated by the application of low dc bias voltages, changing their appearance from transparent to opaque. ...

journal_title：Scientific reports

authors： Bulja S,Kopf R,Tate A,Hu T

更新日期：2016-06-30 00:00:00

abstract：:Due to the lack of a proper imaging approach, a veracious pH map of normal and abnormal cell is still rare. In this work, we presented a rhodamine-salicylaldehyde combination (Rh-SA2) as a novel pH probe, which has dual sensitive units for both acidic and basic environment. This dual sensitive probe acts like a chamel...

journal_title：Scientific reports

authors： Yu KK,Hou JT,Li K,Yao Q,Yang J,Wu MY,Xie YM,Yu XQ

更新日期：2015-10-21 00:00:00

abstract：:Memory function deficits induced by Alzheimer's disease (AD) are believed to be one of the causes of an increased risk of tripping in patients. Working memory contributes to accurate stepping over obstacles during locomotion, and AD-induced deficits of this memory function may lead to an increased risk of contact with...

journal_title：Scientific reports

authors： Setogawa S,Yamaura H,Arasaki T,Endo S,Yanagihara D

更新日期：2014-11-27 00:00:00

abstract：:Western North Pacific tropical cyclone (TC) activity is known to have a significant response to El Niño and Southern Oscillation (ENSO). Among the TC intensity classifications, "super typhoon", is widely used as a symbolic word for warning people about the potential for experiencing the most severe typhoon. This study...

journal_title：Scientific reports

authors： Kang NY,Kim D,Elsner JB

更新日期：2019-03-25 00:00:00

abstract：:Inhaled corticosteroids (ICSs) are widely prescribed in chronic obstructive pulmonary disease (COPD). However, little is known about predictors of ICSs therapeutic response. To investigate whether the variation in glucocorticoid-induced transcript 1 (GLCCI1) rs37973 is associated with ICS efficacy. A total of 204 clin...

journal_title：Scientific reports

authors： Lei Y,Gao Y,Chen J,Li M,Wu X,Ning Q,Zhao J,Xiong W,Xu Y,Xie J

更新日期：2017-02-10 00:00:00

abstract：:Epigenetic deregulation, such as the reduction of histone acetylation levels, is thought to be causally linked to various maladies associated with aging. Consequently, histone deacetylase inhibitors are suggested to serve as epigenetic therapy by increasing histone acetylation. However, previous work suggests that man...

journal_title：Scientific reports

authors： Becker L,Nogueira MS,Klima C,de Angelis MH,Peleg S

更新日期：2018-03-08 00:00:00

abstract：:The ability to assemble nano- and micro- sized colloidal components into highly ordered configurations is often cited as the basis for developing advanced materials. However, the dynamics of stochastic grain boundary formation and motion have not been quantified, which limits the ability to control and anneal polycrys...

journal_title：Scientific reports

authors： Edwards TD,Yang Y,Beltran-Villegas DJ,Bevan MA

更新日期：2014-08-20 00:00:00

abstract：:We report on an angle resolved photoemission (ARPES) study of bulk electron-doped perovskite iridate, (Sr(1-x)La(x))3Ir2O7. Fermi surface pockets are observed with a total electron count in keeping with that expected from La substitution. Depending on the energy and polarization of the incident photons, these pockets ...

journal_title：Scientific reports

authors： He J,Hafiz H,Mion TR,Hogan T,Dhital C,Chen X,Lin Q,Hashimoto M,Lu DH,Zhang Y,Markiewicz RS,Bansil A,Wilson SD,He RH

更新日期：2015-02-23 00:00:00

abstract：:ADHD is a major societal problem with increasing incidence and a stagnant track record for treatment advances. A lack of appropriate animal models has partly contributed to the incremental advance of this field. Hence, our goal was to generate a novel mouse model that could be useful for ADHD medication development. W...

journal_title：Scientific reports

authors： Majdak P,Ossyra JR,Ossyra JM,Cobert AJ,Hofmann GC,Tse S,Panozzo B,Grogan EL,Sorokina A,Rhodes JS

更新日期：2016-12-20 00:00:00

abstract：:Atropa acuminata Royle Ex Lindl (Atropa acuminata) under tremendous threat of extinction in its natural habitat. However, the antimicrobial, antileishmanial and anticancer effects of the plant's extracts have not been reported yet. In the current study, an attempt has been made to evaluate the pharmacological potentia...

journal_title：Scientific reports

authors： Rahman K,Khan SU,Fahad S,Shinwari ZK,Khan D,Kamal S,Ullah I,Anjum SI,Man S,Khan AJ,Khan WU,Khan MHU,Jan M,Adnan M,Noor M

更新日期：2018-07-23 00:00:00

abstract：:In this work, we utilise a combination of theory, computation and experiments to understand the early events related to the nucleation of Ag filaments on α-Ag2WO4 crystals, which is driven by an accelerated electron beam from an electron microscope under high vacuum. The growth process and the chemical composition and...

journal_title：Scientific reports

authors： Andrés J,Gracia L,Gonzalez-Navarrete P,Longo VM,Avansi W Jr,Volanti DP,Ferrer MM,Lemos PS,La Porta FA,Hernandes AC,Longo E

更新日期：2014-06-23 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML version of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Garcia M,Herbst CT,Bowling DL,Dunn JC,Fitch WT

更新日期：2018-01-15 00:00:00

abstract：:Food webs in high-latitude oceans are dominated by relatively few species. Future ocean and sea-ice changes affecting the distribution of such species will impact the structure and functioning of whole ecosystems. Antarctic krill (Euphausia superba) is a key species in Southern Ocean food webs, but there is little und...

journal_title：Scientific reports

authors： Murphy EJ,Thorpe SE,Tarling GA,Watkins JL,Fielding S,Underwood P

更新日期：2017-07-31 00:00:00

abstract：:The aim of this study was to investigate left ventricular (LV) global myocardial strain and LV involvement characteristics in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) and to evaluate their predictive value of adverse cardiac events. Sixty consecutive ARVD/C patients with a defin...

journal_title：Scientific reports

authors： Shen MT,Yang ZG,Diao KY,Jiang L,Zhang Y,Liu X,Gao Y,Hu BY,Huang S,Guo YK

更新日期：2019-10-02 00:00:00

abstract：:Carbon-based nanomaterials such as single-walled carbon nanotubes and reduced graphene oxide are currently being evaluated for biomedical applications including in vivo drug delivery and tumor imaging. Several reports have studied the toxicity of carbon nanomaterials, but their effects on human male reproduction have ...

journal_title：Scientific reports

authors： Asghar W,Shafiee H,Velasco V,Sah VR,Guo S,El Assal R,Inci F,Rajagopalan A,Jahangir M,Anchan RM,Mutter GL,Ozkan M,Ozkan CS,Demirci U

更新日期：2016-08-19 00:00:00

abstract：:Small ruminants, including sheep and goats are natural hosts of scrapie, and the progression of scrapie pathogenesis is strongly influenced by polymorphisms in the prion protein gene (PRNP). Although Korean native goats have been consumed as meat and health food, the evaluation of the susceptibility to scrapie in thes...

journal_title：Scientific reports

authors： Kim SK,Kim YC,Won SY,Jeong BH

更新日期：2019-10-25 00:00:00

abstract：:Marigold (Tagetes erecta L.) is an important ornamental plant with a wide variety of flower colors. Despite its economic value, few biochemical and molecular studies have explored the generation of flower color in this species. To study the mechanism underlying marigold petal color, we performed a metabolite analysis ...

journal_title：Scientific reports

authors： Zhang H,Zhang S,Zhang H,Chen X,Liang F,Qin H,Zhang Y,Cong R,Xin H,Zhang Z

更新日期：2020-10-08 00:00:00