Systemic oxidative stress is associated with lower aerobic capacity and impaired skeletal muscle energy metabolism in heart failure patients.

abstract：:Centromeres usually contain large amounts of tandem repeat DNA. Alpha satellite DNA (AS) is the most abundant tandem repeat DNA found in the centromeres of simian primates. The AS of humans contains sequences organized into higher-order repeat (HOR) structures, which are tandem arrays of larger repeat units consisting...

journal_title：Scientific reports

authors： Sujiwattanarat P,Thapana W,Srikulnath K,Hirai Y,Hirai H,Koga A

更新日期：2015-05-14 00:00:00

abstract：:Traditional radiomics models mainly rely on explicitly-designed handcrafted features from medical images. This paper aimed to investigate if deep features extracted via transfer learning can generate radiomics signatures for prediction of overall survival (OS) in patients with Glioblastoma Multiforme (GBM). This study...

journal_title：Scientific reports

authors： Lao J,Chen Y,Li ZC,Li Q,Zhang J,Liu J,Zhai G

更新日期：2017-09-04 00:00:00

abstract：:This work describes a simple technique to produce porous ceramics with aligned porosity having very high permeability and specific surface area. SiOC-based compositions were processed from blends of three types of preceramic polymer and a catalyst, followed by curing and pyrolysis. The heating applied from the bottom ...

journal_title：Scientific reports

authors： Vakifahmetoglu C,Zeydanli D,Innocentini MD,Ribeiro FD,Lasso PR,Soraru GD

更新日期：2017-01-20 00:00:00

abstract：:The one-step nucleic acid amplification (OSNA) assay is a molecular procedure that can identify deposits of breast cancer (BC) cells in the sentinel lymph node (SLN). We examined the consistency of the OSNA assay with a classic hematoxylin-eosin (H&E)-based immunohistochemistry (IHC) study and evaluated how OSNA-based...

journal_title：Scientific reports

authors： Ruano MA,Lopez-Bonet E,Buxó M,Tuca-Rodríguez F,Vila-Camps E,Alvarez E,Martin-Castillo B,Menendez JA

更新日期：2014-07-18 00:00:00

abstract：:Fossils of the sponge Angulosuspongia sinensis from calcareous mudstones of the middle and upper part of the Kaili Formation (Cambrian Stage 5) in the Jianhe area of Guizhou province, South China, exhibit an apparently reticulate pattern, characteristic of the Vauxiidae. Energy Dispersive X-Ray Spectrometry (EDS) and ...

journal_title：Scientific reports

authors： Yang XL,Zhao YL,Babcock LE,Peng J

更新日期：2017-02-21 00:00:00

abstract：:Root canal treatment is performed to treat apical periodontitis, and various procedures and techniques are currently used. Although animal models have been used in the developmental research of root canal treatment, little of this research has used small animals such as rats, because of their small size. In this study...

journal_title：Scientific reports

authors： Yoneda N,Noiri Y,Matsui S,Kuremoto K,Maezono H,Ishimoto T,Nakano T,Ebisu S,Hayashi M

更新日期：2017-06-12 00:00:00

abstract：:The biological functions of nitric oxide (NO) depend on its concentration, and excessive levels of NO induce various harmful situations known as nitrosative stress. Therefore, organisms possess many kinds of strategies to regulate the intracellular NO concentration and/or to detoxify excess NO. Here, we used genetic s...

journal_title：Scientific reports

authors： Anam K,Nasuno R,Takagi H

更新日期：2020-04-07 00:00:00

abstract：:Cell sorting via flow cytometry is a powerful tool to select subpopulations of cells in many biological fields. Selection of fertilisation-prone sperm is a critical step to ensure a stable and high fertilisation rate in in vitro fertilisation (IVF). However, a combination of conventional cell sorting and IVF system ha...

journal_title：Scientific reports

authors： Nakao S,Takeo T,Watanabe H,Kondoh G,Nakagata N

更新日期：2020-06-01 00:00:00

abstract：:The applications of spin dynamos, which could potentially power complex nanoscopic devices, have so far been limited owing to their extremely low energy conversion efficiencies. Here, we present a unique plasmonic diabolo cavity (PDC) that dramatically improves the spin rectification signal (enhancement of more than t...

journal_title：Scientific reports

authors： Gou P,Qian J,Xi F,Zou Y,Cao J,Yu H,Zhao Z,Yang L,Xu J,Wang H,Zhang L,An Z

更新日期：2017-07-13 00:00:00

abstract：:CD4+latency-associated peptide (LAP)+ T cells are a newly discovered T cell subset with suppressive function on immune responses. In this study, we investigate the role of CD4+LAP+ T cells on mice corneal allograft survival by down-regulating their expression using anti-LAP mAb. We show that a blockage of LAP leads to...

journal_title：Scientific reports

authors： Li S,Lu H,Sella R,Zhang W,Dong H,Guo C,Afshari NA,Pan Z,Jie Y

更新日期：2018-05-22 00:00:00

abstract：:The damping properties and specifically the bend losses of polymer optical fibres (POFs) have so far only been documented by experimental work, investigating bending parameters such as bending radius, length, and distance of the bends. Even though damping mechanisms and causes are well-known, no simple, generally vali...

journal_title：Scientific reports

authors： Lustermann B,Quandt BM,Ulrich S,Spano F,Rossi RM,Boesel LF

更新日期：2020-07-17 00:00:00

abstract：:Network alignment (NA) compares networks with the goal of finding a node mapping that uncovers highly similar (conserved) network regions. Existing NA methods are homogeneous, i.e., they can deal only with networks containing nodes and edges of one type. Due to increasing amounts of heterogeneous network data with nod...

journal_title：Scientific reports

authors： Gu S,Johnson J,Faisal FE,Milenković T

更新日期：2018-08-21 00:00:00

abstract：:Grain size is an important trait influencing both the yield and quality of rice and its major determinant is glume size. However, how glume size is regulated remains largely unknown. Here, we report the characterization of OsKinesin-13A, which regulates cell elongation and glume length in rice. The mutant of OsKinesin...

journal_title：Scientific reports

authors： Deng ZY,Liu LT,Li T,Yan S,Kuang BJ,Huang SJ,Yan CJ,Wang T

更新日期：2015-03-25 00:00:00

abstract：:Living organisms in drying environments build anisotropic structures and exhibit directionality through self-organization of biopolymers. However, the process of macro-scale assembly is still unknown. Here, we introduce a dissipative structure through a non-equilibrium process between hydration and deposition in the d...

journal_title：Scientific reports

authors： Okeyoshi K,Okajima MK,Kaneko T

更新日期：2017-07-21 00:00:00

abstract：:Influenza infection represents a major socio-economic burden worldwide. Novel delivery methods can render influenza vaccination easier and more acceptable by the public, and importantly confer protection equal or superior to that induced by conventional systemic administration. An attractive target for vaccine deliver...

journal_title：Scientific reports

authors： Koutsonanos DG,Vassilieva EV,Stavropoulou A,Zarnitsyn VG,Esser ES,Taherbhai MT,Prausnitz MR,Compans RW,Skountzou I

更新日期：2012-01-01 00:00:00

abstract：:Transcriptome expression reflects genetic response in diverse conditions. In this study, RNA sequencing was utilized to profile multiple tissues such as liver, breast, caecum, and gizzard of Korean commercial chicken raised in Korea and Kyrgyzstan. We analyzed ten samples per tissue from each location to identify cand...

journal_title：Scientific reports

authors： Kumar H,Choo H,Iskender AU,Srikanth K,Kim H,Zhunushov AT,Jang GW,Lim Y,Song KD,Park JE

更新日期：2020-11-06 00:00:00

abstract：:Cover crops (plants grown in an agricultural rotation between cash crops) can significantly improve soil quality via sequestering carbon, retaining nutrients, decreasing soil erosion, and maintaining belowground biodiversity. However, little is known about the effects of such plants upon soil structure. The aim of the...

journal_title：Scientific reports

authors： Bacq-Labreuil A,Crawford J,Mooney SJ,Neal AL,Ritz K

更新日期：2019-05-16 00:00:00

abstract：:We report transport studies on the 5 nm thick Bi₂Se₃ topological insulator films which are grown via molecular beam epitaxy technique. The angle-resolved photoemission spectroscopy data show that the Fermi level of the system lies in the bulk conduction band above the Dirac point, suggesting important contribution of ...

journal_title：Scientific reports

authors： Wang H,Liu H,Chang CZ,Zuo H,Zhao Y,Sun Y,Xia Z,He K,Ma X,Xie XC,Xue QK,Wang J

更新日期：2014-07-24 00:00:00

abstract：:Neurite growth is controlled by a complex molecular signaling network that regulates filamentous actin (F-actin) dynamics at the growth cone. The evolutionarily conserved ezrin, radixin, and moesin family of proteins tether F-actin to the cell membrane when phosphorylated at a conserved threonine residue and modulate ...

journal_title：Scientific reports

authors： Jin EJ,Ko HR,Hwang I,Kim BS,Choi JY,Park KW,Cho SW,Ahn JY

更新日期：2018-02-07 00:00:00

abstract：:Soil physical properties and soil organic carbon (SOC) are considered as important factors of soil quality. Arable land, grassland, and forest land coexist in the saline-alkali reclamation area of the Yellow River Delta (YRD), China. Such different land uses strongly influence the services of ecosystem to induce soil ...

journal_title：Scientific reports

authors： Jiao S,Li J,Li Y,Xu Z,Kong B,Li Y,Shen Y

更新日期：2020-11-23 00:00:00

abstract：:The connection between structure and stability of ecological networks has been widely studied in the last fifty years. A challenge that scientists continue to face is that in-depth mathematical model analysis is often difficult, unless the considered systems are specifically constrained. This makes it challenging to g...

journal_title：Scientific reports

authors： Fischer SM,Huth A

更新日期：2019-10-01 00:00:00

abstract：:Previous research has shown that low-level visual features (i.e., low-level visual saliency) as well as socially relevant information predict gaze allocation in free viewing conditions. However, these studies mainly used static and highly controlled stimulus material, thus revealing little about the robustness of atte...

journal_title：Scientific reports

authors： Rubo M,Gamer M

更新日期：2018-02-28 00:00:00

abstract：:The Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) has been counted on for conserving threatened marine fish since it regulates the commercial international trade of these species. Implementation of the international treaty for Mantas included on CITES Appendix II is challengin...

journal_title：Scientific reports

authors： Zeng Y,Wu Z,Zhang C,Meng Z,Jiang Z,Zhang J

更新日期：2016-11-23 00:00:00

abstract：:Seagrass meadows are threatened by coastal development and global change. In the face of these pressures, molecular techniques such as reverse transcription quantitative real-time PCR (RT-qPCR) have great potential to improve management of these ecosystems by allowing early detection of chronic stress. In RT-qPCR, the...

journal_title：Scientific reports

authors： Schliep M,Pernice M,Sinutok S,Bryant CV,York PH,Rasheed MA,Ralph PJ

更新日期：2015-11-23 00:00:00

abstract：:The C1q complement/TNF-related protein superfamily (CTRPs) displays differential effects on the regulation of metabolic homeostasis, governing cardiovascular function. However, whether and how they may serve as predictor/pro-diagnosis factors for assessing the risks of coronary artery disease (CAD) remains controversi...

journal_title：Scientific reports

authors： Zhang Y,Liu C,Liu J,Guo R,Yan Z,Liu W,Lau WB,Jiao X,Cao J,Xu K,Jia Y,Ma X,Wang Y

更新日期：2020-01-21 00:00:00

abstract：:Hypoxia-inducible factor (HIF)-1α and HIF-2α play an important role in liver fibrosis. von Hippel-Lindau protein (VHL), a key mediator of HIF-α, regulates fibrosis in an organ- and cell-specific way. In this study, human liver samples were collected from hepatitis C-, alcoholic-, and cholestatic-associated fibrotic an...

journal_title：Scientific reports

authors： Wang J,Lu Z,Xu Z,Tian P,Miao H,Pan S,Song R,Sun X,Zhao B,Wang D,Ma Y,Song X,Zhang S,Liu L,Jiang H

更新日期：2017-01-23 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Cardelli C,Bianco V,Rovigatti L,Nerattini F,Tubiana L,Dellago C,Coluzza I

更新日期：2018-03-12 00:00:00

abstract：:The process of second-harmonic generation (SHG) in a finite one-dimensional nonlinear medium is analyzed in parallel by the Green-function technique and the Fourier-transform method. Considering the fundamental pump field propagating along a given direction and eliminating back-reflections at the boundaries the terms ...

journal_title：Scientific reports

authors： Javůrek D,Peřina J Jr

更新日期：2019-03-20 00:00:00

abstract：:A new electrically small antenna with size ka = 0.415 is presented, fabricated and measured in this work. This is intrinsically matched to 50 Ω, has omni-directional and linear-polarized radiation pattern in the horizontal plane with maximum directivity of 1.75 dBi and simulated radiation efficiency of 93%. The antenn...

journal_title：Scientific reports

authors： Assimonis SD,Fusco V,Georgiadis A,Samaras T

更新日期：2018-10-09 00:00:00

abstract：:Allosteric modulation of G protein-coupled receptors represent a promising mechanism of pharmacological intervention. Dramatic developments witnessed in the structural biology of membrane proteins continue to reveal that the binding sites of allosteric modulators are widely distributed, including along protein surface...

journal_title：Scientific reports

authors： Wakefield AE,Mason JS,Vajda S,Keserű GM

更新日期：2019-04-16 00:00:00