GLCCI1 rs37973: a potential genetic predictor of therapeutic response to inhaled corticosteroids in Chinese chronic obstructive pulmonary disease patients.

abstract：:Convergent-margin basins (CMBs) are commonly associated with active arcs, and hence are rich in detrital zircon (DZ) whose ages closely reflect the timing of deposition. Consequently, maximum depositional ages (MDA) from DZ geochronology can be employed to resolve the stratigraphy and evolution of CMBs. Herein, we use...

journal_title：Scientific reports

authors： Huang C,Dashtgard SE,Kent BAP,Gibson HD,Matthews WA

更新日期：2019-10-25 00:00:00

abstract：:Non-invasive imaging of arthritis activity in rheumatoid arthritis (RA) patients using macrophage PET holds promise for early diagnosis and therapeutic response monitoring. Previously obtained results with macrophage tracer (R)-[11C]PK11195 were encouraging, but the imaging signal could be further improved by reductio...

journal_title：Scientific reports

authors： Verweij NJF,Yaqub M,Bruijnen STG,Pieplenbosch S,Ter Wee MM,Jansen G,Chen Q,Low PS,Windhorst AD,Lammertsma AA,Hoekstra OS,Voskuyl AE,van der Laken CJ

更新日期：2020-01-23 00:00:00

abstract：:Exhibiting a red-shifted absorption/scattering feature compared to conventional plasmonic metals, titanium nitride nanoparticles (TiN NPs) look as very promising candidates for biomedical applications, but these applications are still underexplored despite the presence of extensive data for conventional plasmonic coun...

journal_title：Scientific reports

authors： Popov AA,Tselikov G,Dumas N,Berard C,Metwally K,Jones N,Al-Kattan A,Larrat B,Braguer D,Mensah S,Da Silva A,Estève MA,Kabashin AV

更新日期：2019-02-04 00:00:00

abstract：:Peatlands perform important ecosystem functions, such as carbon storage and nutrient retention, which are affected, among other factors, by vegetation and peat decomposition. The availability of silicon (Si) in peatlands differs strongly, ranging from <1 to >25 mg L-1. Since decomposition of organic material was recen...

journal_title：Scientific reports

authors： Reithmaier GS,Knorr KH,Arnhold S,Planer-Friedrich B,Schaller J

更新日期：2017-08-18 00:00:00

abstract：:In vitro recapitulation of an organotypic stromal environment, enabling efficient angiogenesis, is crucial to investigate and possibly improve vascularization in regenerative medicine. Our study aims at engineering the complexity of a vascular milieu including multiple cell-types, a stromal extracellular matrix (ECM),...

journal_title：Scientific reports

authors： Cerino G,Gaudiello E,Muraro MG,Eckstein F,Martin I,Scherberich A,Marsano A

更新日期：2017-10-27 00:00:00

abstract：:Frequent self-monitoring of blood glucose (SMBG) is the only accurate method available for insulin dose titration in patients with T1DM. Professional continuous glucose monitoring (p-CGM) is blinded recording of glucose trends over 5-7 days and helps physicians to guide insulin titration to patient. This study was pla...

journal_title：Scientific reports

authors： Raviteja KV,Kumar R,Dayal D,Sachdeva N

更新日期：2019-04-16 00:00:00

abstract：:The importance of evaluating physical cues in cancer research is gradually being realized. Assessment of cancer cell physical appearance, or phenotype, may provide information on changes in cellular behavior, including migratory or communicative changes. These characteristics are intrinsically different between malign...

journal_title：Scientific reports

authors： Ware MJ,Tinger S,Colbert KL,Corr SJ,Rees P,Koshkina N,Curley S,Summers HD,Godin B

更新日期：2015-07-13 00:00:00

abstract：:The temporal correspondence between two arbitrarily chosen pairs of alternating features can generally be reported for rates up to 3-4 Hz. This limit is however surpassed for specialised visual mechanisms that encode conjunctions of features. Here we show that this 3-4 Hz limit is exceeded for eye gaze and eyebrow pai...

journal_title：Scientific reports

authors： Harrison C,Binetti N,Mareschal I,Johnston A

更新日期：2018-06-13 00:00:00

abstract：:The porosity and utilization of platinum catalysts have a direct impact on their performance within proton exchange membrane fuel cells. It is desirable to identify methods that can prepare these catalysts with the desired features, and that can be widely implemented using existing and industrially scalable techniques...

journal_title：Scientific reports

authors： Paul MTY,Gates BD

更新日期：2019-03-11 00:00:00

abstract：:Non-Alcoholic Fatty Liver Disease (NAFLD) represents the most common form of chronic liver injury and can progress to cirrhosis and hepatocellular carcinoma. A "multi-hit" theory, involving high fat diet and signals from the gut-liver axis, has been hypothesized. The role of the NLRP3-inflammasome, which senses danger...

journal_title：Scientific reports

authors： Pierantonelli I,Rychlicki C,Agostinelli L,Giordano DM,Gaggini M,Fraumene C,Saponaro C,Manghina V,Sartini L,Mingarelli E,Pinto C,Buzzigoli E,Trozzi L,Giordano A,Marzioni M,Minicis S,Uzzau S,Cinti S,Gastaldelli A,Sveg

更新日期：2017-09-22 00:00:00

abstract：:A method is proposed to drive an ultrafast non-adiabatic dynamics of an ultracold gas trapped in a time-dependent box potential. The resulting state is free from spurious excitations associated with the breakdown of adiabaticity, and preserves the quantum correlations of the initial state up to a scaling factor. The p...

journal_title：Scientific reports

authors： del Campo A,Boshier MG

更新日期：2012-01-01 00:00:00

abstract：:Nitric oxide (NO) is an important signalling molecule involved in haemostasis. NO, present as endogenous S-nitrosothiols, is released by cysteine through a transnitrosation reaction. To exploit this mechanism, cysteine was immobilised onto the different carboxylated polyethylene terephthalate (PET) surfaces using 1-st...

journal_title：Scientific reports

authors： Ramachandran B,Muthuvijayan V

更新日期：2019-11-13 00:00:00

abstract：:Hypoxia inducible factor-1α (HIF-1α) pathway is associated with many vascular diseases, including atherosclerosis, arterial aneurysms, pulmonary hypertension and chronic venous diseases. Significant HIF-1α expression could be found at the rupture edge at human abdominal aortic aneurysm (AAA) tissues. While our initial...

journal_title：Scientific reports

authors： Tsai SH,Huang PH,Hsu YJ,Peng YJ,Lee CH,Wang JC,Chen JW,Lin SJ

更新日期：2016-07-01 00:00:00

abstract：:Niemann-Pick type C1 (NPC1) disease is a rare autosomal recessive, neurodegenerative lysosomal storage disorder, which presents with a range of clinical phenotypes and hence diagnosis remains a challenge. In view of these difficulties, the search for a novel, NPC1-specific biomarker (or set of biomarkers) is a topic o...

journal_title：Scientific reports

authors： Probert F,Ruiz-Rodado V,Vruchte DT,Nicoli ER,Claridge TDW,Wassif CA,Farhat N,Porter FD,Platt FM,Grootveld M

更新日期：2017-07-24 00:00:00

abstract：:Metal nitrides have been proposed to replace noble metals in plasmonics for some specific applications. In particular, while titanium nitride (TiN) and zirconium nitride (ZrN) possess localized plasmon resonances very similar to gold in magnitude and wavelength, they benefit from a much higher sustainability to temper...

journal_title：Scientific reports

authors： Lalisse A,Tessier G,Plain J,Baffou G

更新日期：2016-12-09 00:00:00

abstract：:In this study, a rational combination of 200 pre-selected Carbohydrate-Active enzymes (CAZymes) and sulfatases were tested, individually or combined, according to their ability to degrade Chlorella vulgaris cell wall to access its valuable nutritional compounds. The disruption of microalgae cell walls by a four-enzyme...

journal_title：Scientific reports

authors： Coelho D,Lopes PA,Cardoso V,Ponte P,Brás J,Madeira MS,Alfaia CM,Bandarra NM,Gerken HG,Fontes CMGA,Prates JAM

更新日期：2019-03-29 00:00:00

abstract：:Magnetic oscillation is a generic property of electronic conductors under magnetic fields and widely appreciated as a useful probe of their electronic band structure, i.e. the Fermi surface geometry. However, the usage of the strong static magnetic field makes the measurement insensitive to the magnetic order of the t...

journal_title：Scientific reports

authors： Fujita H,Sato M

更新日期：2018-10-24 00:00:00

abstract：:Therapies using mesenchymal stem cell (MSC) seeded scaffolds may be applicable to various fields of regenerative medicine, including craniomaxillofacial surgery. Plastic compression of collagen scaffolds seeded with MSC has been shown to enhance the osteogenic differentiation of MSC as it increases the collagen fibril...

journal_title：Scientific reports

authors： Chamieh F,Collignon AM,Coyac BR,Lesieur J,Ribes S,Sadoine J,Llorens A,Nicoletti A,Letourneur D,Colombier ML,Nazhat SN,Bouchard P,Chaussain C,Rochefort GY

更新日期：2016-12-09 00:00:00

abstract：:We report here that CYB5D2 is associated with tumor suppression function in breast cancer (BC). CYB5D2 expression was significantly reduced in tamoxifen resistant MCF7 cells and in MCF7 cell-derived xenografts treated with TAM. CYB5D2 overexpression induced apoptosis in MCF7 cells; CYB5D2 knockdown enhanced MCF7 cell ...

journal_title：Scientific reports

authors： Ojo D,Rodriguez D,Wei F,Bane A,Tang D

更新日期：2019-04-29 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Sheu JR,Chen ZC,Jayakumar T,Chou DS,Yen TL,Lee HN,Pan SH,Hsia CH,Yang CH,Hsieh CY

更新日期：2020-04-06 00:00:00

abstract：:Autism is a common and often severe neurodevelopmental disorder for which diverse pathophysiological processes have been proposed. Recent gene expression data comparing autistic and control brains suggest that the normal differential gene expression between frontal and temporal cortex is attenuated in autistic brains....

journal_title：Scientific reports

authors： Ginsberg MR,Rubin RA,Natowicz MR

更新日期：2013-01-01 00:00:00

abstract：:Neutrophil gelatinase-associated lipocalin (NGAL, lipocalin 2 or LCN2) is an iron carrier protein whose circulating level is increased by kidney injury, bacterial infection and obesity, but its metabolic consequence remains elusive. To study physiological role of LCN2 in energy homeostasis, we challenged female Lcn2 k...

journal_title：Scientific reports

authors： Ishii A,Katsuura G,Imamaki H,Kimura H,Mori KP,Kuwabara T,Kasahara M,Yokoi H,Ohinata K,Kawanishi T,Tsuchida J,Nakamoto Y,Nakao K,Yanagita M,Mukoyama M,Mori K

更新日期：2017-11-14 00:00:00

abstract：:Wooden shipwrecks are a significant part of the underwater cultural heritage. In 2007, the Nanhai No. 1 shipwreck was salvaged from the seabed and moved into the Marine Silk Road Museum, where it is still stored in a water tank. We analysed the microbial communities colonizing the hull surface of the Nanhai No. 1 ship...

journal_title：Scientific reports

authors： Liu Z,Fu T,Hu C,Shen D,Macchioni N,Sozzi L,Chen Y,Liu J,Tian X,Ge Q,Feng Z,Liu H,Zhang Z,Pan J

更新日期：2018-05-08 00:00:00

abstract：:Balancing the amounts of enzymes is one of the important factors to achieve optimum performance of a designed metabolic pathway. However, the random mutagenesis approach is impractical since it requires searching an unnecessarily large number of variants and often results in searching a narrow range of expression leve...

journal_title：Scientific reports

authors： Seo SW,Yang JS,Cho HS,Yang J,Kim SC,Park JM,Kim S,Jung GY

更新日期：2014-03-31 00:00:00

abstract：:Rhythmically bedded cherts are observed in both pelagic marine and lacustrine deposits, but the formation mechanism in the latter remains highly uncertain. Our study of alternating chert-dolomite beds in the Eocene Green River Formation, Utah, USA reveals dense accumulations of organic-matter spheres (30-50 μm diamete...

journal_title：Scientific reports

authors： Kuma R,Hasegawa H,Yamamoto K,Yoshida H,Whiteside JH,Katsuta N,Ikeda M

更新日期：2019-11-11 00:00:00

abstract：:Fitness-related costs of evolving insecticide resistance have been reported in a number of insect species, but the interplay between evolutionary adaptation to insecticide pressure and variable environmental conditions has received little attention. We provisioned nymphs from three German cockroach (Blattella germanic...

journal_title：Scientific reports

authors： Jensen K,Ko AE,Schal C,Silverman J

更新日期：2016-06-27 00:00:00

abstract：:A reduction in the particle size is expected to improve the properties and increase the application potential of high-entropy alloys. Therefore, in this study, a novel sol-gel autocombustion technique was first used to synthesize high-entropy alloys. The average grain size of the prepared nanocrystalline CoCrCuNiAl hi...

journal_title：Scientific reports

authors： Niu B,Zhang F,Ping H,Li N,Zhou J,Lei L,Xie J,Zhang J,Wang W,Fu Z

更新日期：2017-06-13 00:00:00

abstract：:A cross-correlative precession electron diffraction - atom probe tomography investigation of Cr segregation in a Fe(Cr) nanocrystalline alloy was undertaken. Solute segregation was found to be dependent on grain boundary type. The results of which were compared to a hybrid Molecular Dynamics and Monte Carlo simulation...

journal_title：Scientific reports

authors： Zhou X,Yu XX,Kaub T,Martens RL,Thompson GB

更新日期：2016-10-06 00:00:00

abstract：:Arctic amplification of global warming has led to increased summer sea ice retreat, which influences gas exchange between the Arctic Ocean and the atmosphere where sea ice previously acted as a physical barrier. Indeed, recently observed enhanced atmospheric methane concentrations in Arctic regions with fractional sea...

journal_title：Scientific reports

authors： Damm E,Rudels B,Schauer U,Mau S,Dieckmann G

更新日期：2015-11-10 00:00:00

abstract：:The emergence of metallic conduction in layered dichalcogenide semiconductor materials by chemical doping is one of key issues for two-dimensional (2D) materials engineering. At present, doping methods for layered dichalcogenide materials have been limited to an ion intercalation between layer units or electrostatic c...

journal_title：Scientific reports

authors： Kim SI,Hwang S,Kim SY,Lee WJ,Jung DW,Moon KS,Park HJ,Cho YJ,Cho YH,Kim JH,Yun DJ,Lee KH,Han IT,Lee K,Sohn Y

更新日期：2016-01-21 00:00:00