Author Correction: A novel indication of platonin, a therapeutic immunomodulating medicine, on neuroprotection against ischemic stroke in mice.

abstract：:In recent years it has been shown that the therapeutic benefits of human mesenchymal stem/stromal cells (hMSCs) in the Central Nervous System (CNS) are mainly attributed to their secretome. The implementation of computer-controlled suspension bioreactors has shown to be a viable route for the expansion of these cells ...

journal_title：Scientific reports

authors： Teixeira FG,Panchalingam KM,Assunção-Silva R,Serra SC,Mendes-Pinheiro B,Patrício P,Jung S,Anjo SI,Manadas B,Pinto L,Sousa N,Behie LA,Salgado AJ

更新日期：2016-06-15 00:00:00

abstract：:Effective treatment of osteomyelitis remains a formidable clinical challenge. The rapid emergence of multidrug-resistant bacteria has renewed interest in developing antimicrobial biomaterials using antiseptic silver ions to treat osteomyelitis. However, inadequate local retention and severe cytotoxic effects have limi...

journal_title：Scientific reports

authors： Lu M,Liao J,Dong J,Wu J,Qiu H,Zhou X,Li J,Jiang D,He TC,Quan Z

更新日期：2016-12-16 00:00:00

abstract：:The influence of the growth conditions of multilayer CdTe/ZnTe quantum dots (QDs) on Si substrate upon their carrier dynamics is studied using intensity integration and broadening photoluminescence. The unusual temperature dependence of the line broadening is explained using a model for interband transitions that invo...

journal_title：Scientific reports

authors： Man MT,Lee HS

更新日期：2015-02-05 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Achouri K,Caloz C

更新日期：2018-07-03 00:00:00

abstract：:Since 2001, hundreds of thousands of hours of underwater acoustic recordings have been made throughout the Southern Ocean south of 60° S. Detailed analysis of the occurrence of marine mammal sounds in these circumpolar recordings could provide novel insights into their ecology, but manual inspection of the entirety of...

journal_title：Scientific reports

authors： Miller BS,IWC-SORP\/SOOS Acoustic Trends Working Group.,Balcazar N,Nieukirk S,Leroy EC,Aulich M,Shabangu FW,Dziak RP,Lee WS,Hong JK

更新日期：2021-01-12 00:00:00

abstract：:The benzodiazepine midazolam is widely used in critical care medicine. Midazolam has a clinically active metabolite, 1-hydroxymidazolam. The contribution of 1-hydroxymidazolam to the effects of midazolam is controversial. The aim of the current study was to compare the actions of midazolam and 1-hydroxymidazolam on ne...

journal_title：Scientific reports

authors： Balk M,Hentschke H,Rudolph U,Antkowiak B,Drexler B

更新日期：2017-06-14 00:00:00

abstract：:Cancer cells can have a broad scope of proliferation rates. Here we aim to identify the molecular mechanisms that allow some cancer cell lines to grow up to 4 times faster than other cell lines. The correlation of gene expression profiles with the growth rate in 60 different cell lines has been analyzed using several ...

journal_title：Scientific reports

authors： Feizi A,Bordel S

更新日期：2013-10-24 00:00:00

abstract：:Plant cis-elements play important roles in global regulation of gene expression. Based on microarray data from rice flag leaves during early senescence, we identified W-box and G-box cis-elements as positive regulators of senescence in the important rice variety Minghui 63. Both cis-elements were bound by leaf senesce...

journal_title：Scientific reports

authors： Liu L,Xu W,Hu X,Liu H,Lin Y

更新日期：2016-02-11 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Shkarina S,Shkarin R,Weinhardt V,Melnik E,Vacun G,Kluger PJ,Loza K,Epple M,Ivlev SI,Baumbach T,Surmeneva MA,Surmenev RA

更新日期：2018-11-29 00:00:00

abstract：:Once assumed only to be a waste product of anaerobe glycolytic activity, lactate is now recognized as an energy source in skeletal muscles. While lactate metabolism has been extensively studied in vivo, underlying cellular processes are poorly described. This study aimed to examine lactate metabolism in cultured human...

journal_title：Scientific reports

authors： Lund J,Aas V,Tingstad RH,Van Hees A,Nikolić N

更新日期：2018-06-29 00:00:00

abstract：:The search for efficient chemotherapy drugs and other anti-cancer treatments would benefit from a deeper understanding of the tumor microenvironment (TME) and its role in tumor progression. Because in vivo experimental methods are unable to isolate or control individual factors of the TME and in vitro models often do ...

journal_title：Scientific reports

authors： Nikmaneshi MR,Firoozabadi B,Mozafari A,Munn LL

更新日期：2020-02-20 00:00:00

abstract：:Toll-like receptors (TLRs), as innate immunity sensors, play critical roles in immune responses. Six SNPs of TLR3, TLR7, and TLR8 were genotyped to determine their associations with systemic lupus erythematosus (SLE) and clinical manifestations of SLE. TLR7 SNP rs3853839 was independently associated with SLE susceptib...

journal_title：Scientific reports

authors： Wang CM,Chang SW,Wu YJ,Lin JC,Ho HH,Chou TC,Yang B,Wu J,Chen JY

更新日期：2014-01-21 00:00:00

abstract：:Compression of optical pulses to ultrashort pulse widths using methods of nonlinear optics is a well-established technology of modern laser science. Extending these methods to pulses with high peak powers, which become available due to the rapid progress of laser technologies, is, however, limited by the universal phy...

journal_title：Scientific reports

authors： Voronin AA,Zheltikov AM

更新日期：2017-04-03 00:00:00

abstract：:Bacteriophage capsids constitute icosahedral shells of exceptional stability that protect the viral genome. Many capsids display on their surface decoration proteins whose structure and function remain largely unknown. The decoration protein pb10 of phage T5 binds at the centre of the 120 hexamers formed by the major ...

journal_title：Scientific reports

authors： Vernhes E,Renouard M,Gilquin B,Cuniasse P,Durand D,England P,Hoos S,Huet A,Conway JF,Glukhov A,Ksenzenko V,Jacquet E,Nhiri N,Zinn-Justin S,Boulanger P

更新日期：2017-02-06 00:00:00

abstract：:The security of quantum key distribution (QKD) is established by a security proof, and the security proof puts some assumptions on the devices consisting of a QKD system. Among such assumptions, security proofs of the six-state protocol assume the use of photon number resolving (PNR) detector, and as a result the bit ...

journal_title：Scientific reports

authors： Kato G,Tamaki K

更新日期：2016-07-22 00:00:00

abstract：:Complex systems performing spiking dynamics are widespread in Nature. They cover from earthquakes, to neurons, variable stars, social networks, or stock markets. Understanding and characterizing their dynamics is relevant in order to detect transitions, or to predict unwanted extreme events. Here we study, under an or...

journal_title：Scientific reports

authors： Colet M,Aragoneses A

更新日期：2018-07-16 00:00:00

abstract：:Layered-structure materials are currently relevant given their quasi-2D nature. Knowledge of their physical properties is currently of major interest. Niobium ditelluride possesses a monoclinic layered-structure with a distortion in the tellurium planes. This structural complexity has hindered the determination of its...

journal_title：Scientific reports

authors： Barajas-Aguilar AH,Irwin JC,Garay-Tapia AM,Schwarz T,Paraguay Delgado F,Brodersen PM,Prinja R,Kherani N,Jiménez Sandoval SJ

更新日期：2018-11-19 00:00:00

abstract：:An understanding of all aspects of fluoride metabolism is critical to identify its biological effects and avoid fluoride toxicity in humans. Fluoride metabolism and subsequently its body retention may be affected by physiological responses to acute exercise. This pilot study investigated the effect of exercise on plas...

journal_title：Scientific reports

authors： V Zohoori F,Innerd A,Azevedo LB,Whitford GM,Maguire A

更新日期：2015-11-19 00:00:00

abstract：:Bronchoconstrictive airway disorders such as asthma are characterized by inflammation and increases in reactive oxygen species (ROS), which produce a highly oxidative environment. β2-adrenergic receptor (β2AR) agonists are a mainstay of clinical therapy for asthma and provide bronchorelaxation upon inhalation. We have...

journal_title：Scientific reports

authors： Rambacher KM,Moniri NH

更新日期：2020-02-19 00:00:00

abstract：:Understanding factors associated with tie strength in social networks is essential in a wide variety of settings. With the internet and cellular phones providing additional avenues of communication, measuring and inferring tie strength has become much more complex. We introduce the social bow tie framework, which cons...

journal_title：Scientific reports

authors： Mattie H,Engø-Monsen K,Ling R,Onnela JP

更新日期：2018-06-19 00:00:00

abstract：:Nano-suspensions (NS) exhibit unusual thermophysical behaviors once interparticle aggregations and the shear flows are imposed, which occur ubiquitously in applications but remain poorly understood, because existing theories have not paid these attentions but focused mainly on stationary NS. Here we report the critica...

journal_title：Scientific reports

authors： Sui J,Zhao P,Bin-Mohsin B,Zheng L,Zhang X,Cheng Z,Chen Y,Chen G

更新日期：2016-12-20 00:00:00

abstract：:Chronic lymphocytic leukaemia (CLL) is characterised by a heterogeneous clinical course. Such heterogeneity is associated with a number of markers, including TP53 gene inactivation. While TP53 gene alterations determine resistance to chemotherapy, it is not clear whether they can influence early disease progression. T...

journal_title：Scientific reports

authors： Monti P,Lionetti M,De Luca G,Menichini P,Recchia AG,Matis S,Colombo M,Fabris S,Speciale A,Barbieri M,Gentile M,Zupo S,Dono M,Ibatici A,Neri A,Ferrarini M,Fais F,Fronza G,Cutrona G,Morabito F

更新日期：2020-10-28 00:00:00

abstract：:To investigate the safety, cost-effectiveness, and clinical outcomes of simultaneous bilateral total knee arthroplasty (TKA) in hemophilic arthropathy (HA), the requirements for transfusions, complications, costs, hospital stays, Hospital for Special Surgery (HSS) knee scores, knee range of motion (ROM) and revision r...

journal_title：Scientific reports

authors： Jiang C,Zhao Y,Feng B,Zhai J,Bian Y,Qiu G,Weng X

更新日期：2018-01-25 00:00:00

abstract：:Stress-induced alteration in endothelial cells (ECs) integrity precedes the development of atherosclerosis. Previous studies showed that the soluble recombinant thrombomodulin (rTM) not only increases ECs proliferation but also exerts anti-apoptotic activity in ECs. However, the functional significance of soluble rTM ...

journal_title：Scientific reports

authors： Chen PS,Wang KC,Chao TH,Chung HC,Tseng SY,Luo CY,Shi GY,Wu HL,Li YH

更新日期：2017-06-12 00:00:00

abstract：:High operating temperatures can have very deleterious effects on the long-term performance of high-Cr, creep-resistant steels used, for example, in the structural components of power plants. For the popular creep-resistant steel X20CrMoV12.1 we analysed the processes of carbide growth using a variety of analytical tec...

journal_title：Scientific reports

authors： Godec M,Skobir Balantič DA

更新日期：2016-07-13 00:00:00

abstract：:Statins present many beneficial effects in chronic liver disease, but concerns about safety exist. We evaluated the hepatic effects of a nitric oxide-releasing atorvastatin (NCX 6560) compared to conventional statins. Simvastatin, atorvastatin and NCX 6560 were evaluated in four-week bile duct-ligated rats (BDL) simul...

journal_title：Scientific reports

authors： Rodríguez S,Raurell I,Torres-Arauz M,García-Lezana T,Genescà J,Martell M

更新日期：2017-01-13 00:00:00

abstract：:Obesity affects male fertility and maternal diabetes affects the offspring sperm epigenome. However, the effects of in utero exposure to maternal glucose intolerance in combination with postnatal high fat, high sucrose (HFHS) diet consumption on offspring spermatogenesis is not clear. The present study was designed to...

journal_title：Scientific reports

authors： Mao J,Pennington KA,Talton OO,Schulz LC,Sutovsky M,Lin Y,Sutovsky P

更新日期：2018-05-16 00:00:00

abstract：:Accumulating evidence suggests that the gut microbiota dysbiosis and their host metabolic phenotype alteration is an important factor in human disease development. A traditional Chinese herbal formula, Chaihu-Shu-Gan-San (CSGS), has been effectively used in the treatment of various gastrointestinal (GI) disorders. The...

journal_title：Scientific reports

authors： Yu M,Jia HM,Zhou C,Yang Y,Sun LL,Zou ZM

更新日期：2017-04-20 00:00:00

abstract：:CIC-DUX4 sarcoma (CDS) is a group of rare, mesenchymal, small round cell tumours that harbour the unique CIC-DUX4 translocation, which causes aberrant gene expression. CDS exhibits an aggressive course and poor clinical outcome, thus novel therapeutic approaches are needed for CDS treatment. Although patient-derived c...

journal_title：Scientific reports

authors： Oyama R,Takahashi M,Yoshida A,Sakumoto M,Takai Y,Kito F,Shiozawa K,Qiao Z,Arai Y,Shibata T,Araki Y,Endo M,Kawai A,Kondo T

更新日期：2017-07-05 00:00:00

abstract：:We found that the coagulation and cytokine pathways were important mechanisms involve in the degeneration of intervertebral discs (IVD) using a microarray approach to analyze gene expression in different grades of specimens. Furthermore, using a cytokine/chemokine array, a significant increase in CXCL8 expression was ...

journal_title：Scientific reports

authors： Huang BR,Chen TS,Bau DT,Chuang IC,Tsai CF,Chang PC,Lu DY

更新日期：2017-08-17 00:00:00