Recombinant Thrombomodulin Exerts Anti-autophagic Action in Endothelial Cells and Provides Anti-atherosclerosis Effect in Apolipoprotein E Deficient Mice.

abstract：:There is a growing need for low-cost, portable technologies for the detection of threats to the environment and human health. Here we propose a label-free, optical whole-cell Escherichia coli biosensor for the detection of 3-phenoxybenzoic acid (3-PBA), a biomarker for monitoring human exposure to synthetic pyrethroid...

journal_title：Scientific reports

authors： Riangrungroj P,Bever CS,Hammock BD,Polizzi KM

更新日期：2019-08-28 00:00:00

abstract：:Stress is one of major factors that cause sleep problems. Hypocretin represents a stress-related neuropeptide and is well known in maintaining physiological wakefulness. The hypocretinergic neurons originate in the lateral hypothalamic area (LHA) and transmit to several brain regions, including the median raphe nuclei...

journal_title：Scientific reports

authors： Hsiao YT,Lo Y,Yi PL,Chang FC

更新日期：2019-06-03 00:00:00

abstract：:Recently, the discovery of room temperature magnetoelectricity in organic charge transfer complexes has reignited interest in the multiferroic field. The solution processed, large-area and low cost organic semiconductor materials offer new possibilities for the functional all organic multiferroic devices. Here we repo...

journal_title：Scientific reports

authors： Han S,Yang L,Gao K,Xie S,Qin W,Ren S

更新日期：2016-06-23 00:00:00

abstract：:A crystalline solid exhibits thermally induced localised non-affine droplets in the absence of external stress. Here we show that upon an imposed shear, the size of these droplets grow until they percolate at a critical strain, well below the value at which the solid begins to yield. This critical point does not manif...

journal_title：Scientific reports

authors： Das T,Ganguly S,Sengupta S,Rao M

更新日期：2015-06-03 00:00:00

abstract：:Therapeutic application of newly developed oximes is limited due to their adverse effects on different tissues. Within this article, it has been investigated which morphological changes could be observed in Wistar rats after the treatment with increasing doses of selected acetyl cholinesterase reactivators - asoxime, ...

journal_title：Scientific reports

authors： Jaćević V,Nepovimova E,Kuča K

更新日期：2019-02-06 00:00:00

abstract：:The critical role of the regulatory elements at the 5' end of the HIV-1 genome in controlling the life cycle of HIV-1 indicates that this region significantly influences virus fitness and its biological properties. In this study, we performed a detailed characterization of strain-specific variability of sequences from...

journal_title：Scientific reports

authors： Mbondji-Wonje C,Dong M,Zhao J,Wang X,Nanfack A,Ragupathy V,Sanchez AM,Denny TN,Hewlett I

更新日期：2020-08-06 00:00:00

abstract：:Nutrient resorption processes in the plants infected by pathogen remain poorly understood. Huanglongbing (HLB) is a destructive disease of citrus. HLB-pathogen 'Candidatus Liberibacter asiaticus' grows specifically in the phloem of hosts and may cause problems in the plant vascular system after infection. Therefore, i...

journal_title：Scientific reports

authors： Cao J,Cheng C,Yang J,Wang Q

更新日期：2015-09-30 00:00:00

abstract：:With new degrees of freedom to achieve full control of the optical wavefront, metasurfaces could overcome the fabrication embarrassment faced by the metamaterials. In this paper, a broadband hologram using metasurface consisting of elongated nanoapertures array with different orientations has been experimentally demon...

journal_title：Scientific reports

authors： Zhang X,Jin J,Wang Y,Pu M,Li X,Zhao Z,Gao P,Wang C,Luo X

更新日期：2016-01-28 00:00:00

abstract：:The spatial distributions of diverse facilities are often understood in terms of the optimization of the commute distance or the economic profit. Incorporating more general objective functions into such optimization framework may be useful, helping the policy decisions to meet various social and economic demands. As a...

journal_title：Scientific reports

authors： Lee MJ,Kim K,Son J,Lee DS

更新日期：2020-05-25 00:00:00

abstract：:Triple-doped (Yb(3+)/Er(3+)/Tm(3+)) KMnF3 nanocubes with uniform sizes of 250 nm were synthesized by a facile hydrothermal route using the oleic acid as the capping agent. It was found that these nanocubes can simultaneously exhibited four-color (blue, green, red and NIR) upconversion emissions under a single 980 nm n...

journal_title：Scientific reports

authors： Wang H,Hong X,Han R,Shi J,Liu Z,Liu S,Wang Y,Gan Y

更新日期：2015-11-26 00:00:00

abstract：:Rapid and efficient processing of external information by the brain is vital to survival in a highly dynamic environment. The key channel humans use to exchange information is language, but the neural underpinnings of its processing are still not fully understood. We investigated the spatio-temporal dynamics of neural...

journal_title：Scientific reports

authors： Shtyrov Y,MacGregor LJ

更新日期：2016-05-24 00:00:00

abstract：:Alpha synuclein (α-syn) is a central player in neurodegeneration, but the mechanisms triggering its pathology are not fully understood. Here we found that α-syn is a highly efficient substrate for arginyltransferase ATE1 and is arginylated in vivo by a novel mid-chain mechanism that targets the acidic side chains of E...

journal_title：Scientific reports

authors： Wang J,Han X,Leu NA,Sterling S,Kurosaka S,Fina M,Lee VM,Dong DW,Yates JR 3rd,Kashina A

更新日期：2017-09-12 00:00:00

abstract：:Incompatible patterns viewed by each of the two eyes can provoke binocular rivalry, a competition of perception. Levelt's first law predicts that a highly visible stimulus will predominate over a less visible stimulus during binocular rivalry. In a behavioural study, we made a counterintuitive observation: high visibi...

journal_title：Scientific reports

authors： Skerswetat J,Formankiewicz MA,Waugh SJ

更新日期：2018-09-26 00:00:00

abstract：:Despite strong evidence for NMDA receptor (NMDAR) hypofunction as an underlying factor for cognitive disorders, the precise roles of various NMDAR subtypes remains unknown. The GluN2C-containing NMDARs exhibit unique biophysical properties and expression pattern, and lower expression of GluN2C subunit has been reporte...

journal_title：Scientific reports

authors： Gupta SC,Ravikrishnan A,Liu J,Mao Z,Pavuluri R,Hillman BG,Gandhi PJ,Stairs DJ,Li M,Ugale RR,Monaghan DT,Dravid SM

更新日期：2016-12-06 00:00:00

abstract：:Thermal perception is essential for the survival and daily activities of people. Thus, it is desirable to realize thermal feedback stimulation for improving the sense of realism in virtual reality (VR) for users. For thermal stimulus, conventional systems utilize liquid circulation with bulky external sources or therm...

journal_title：Scientific reports

authors： Kim SW,Kim SH,Kim CS,Yi K,Kim JS,Cho BJ,Cha Y

更新日期：2020-07-09 00:00:00

abstract：:Development of novel anti-influenza A virus (IAV) drugs with high efficiency and low toxicity is critical for preparedness against influenza outbreaks. Herein, we investigated the anti-IAV activities and mechanisms of fucoidan in vitro and in vivo. The results showed that a fucoidan KW derived from brown algae Kjellma...

journal_title：Scientific reports

authors： Wang W,Wu J,Zhang X,Hao C,Zhao X,Jiao G,Shan X,Tai W,Yu G

更新日期：2017-01-17 00:00:00

abstract：:During action observation, several visual features of observed actions can modulate the level of sensorimotor reactivity in the onlooker. Among possibly relevant parameters, one of the less investigated in humans is the visual perspective from which actions are observed. In the present EEG study, we assessed the react...

journal_title：Scientific reports

authors： Angelini M,Fabbri-Destro M,Lopomo NF,Gobbo M,Rizzolatti G,Avanzini P

更新日期：2018-08-20 00:00:00

abstract：:Metastasis is generally considered a characteristic of malignant tumors. Herein, we describe a patient with more than one hundred discrete Spitz nevi scattered all over her skin. Molecular analysis from three of the lesions identified a ROS1 fusion oncogene with identical genomic breakpoints, indicating that the nevi ...

journal_title：Scientific reports

authors： Raghavan SS,Kapler ES,Dinges MM,Bastian BC,Yeh I

更新日期：2020-10-01 00:00:00

abstract：:To investigate the role of the altered activation of the immune system in the prognosis of patients affected by laryngeal squamous cell carcinoma (LSCC). We analyzed 56 patients with advanced LSCC divided into two groups according to their prognosis: the first group relapsed within 24 months after treatment, the secon...

journal_title：Scientific reports

authors： Tagliabue M,Maffini F,Fumagalli C,Gandini S,Lepanto D,Corso F,Cacciola S,Ranghiero A,Rappa A,Vacirca D,Cossu Rocca M,Alterio D,Guerini Rocco E,Cattaneo A,Chu F,Zorzi S,Curigliano G,Chiocca S,Barberis M,Viale G,Ans

更新日期：2020-10-27 00:00:00

abstract：:Bone tissues have trabecular bone with a high bone turnover and cortical bone with a low turnover. The mechanisms by which the turnover rate of these bone tissues is determined remain unclear. Osteocytes secrete sclerostin, a Wnt/β-catenin signaling antagonist, and inhibit bone formation. We found that sclerostin expr...

journal_title：Scientific reports

authors： Koide M,Yamashita T,Murakami K,Uehara S,Nakamura K,Nakamura M,Matsushita M,Ara T,Yasuda H,Penninger JM,Takahashi N,Udagawa N,Kobayashi Y

更新日期：2020-08-13 00:00:00

abstract：:In spite of much work on topological insulators (TIs), systematic experiments for TI/TI heterostructures remain absent. We grow a high quality heterostructure containing single quintuple layer (QL) of Bi2Se3 on 19 QLs of Bi2Te3 and compare its transport properties with 20 QLs Bi2Se3 and 20 QLs Bi2Te3. All three films ...

journal_title：Scientific reports

authors： Zhao Y,Chang CZ,Jiang Y,DaSilva A,Sun Y,Wang H,Xing Y,Wang Y,He K,Ma X,Xue QK,Wang J

更新日期：2013-10-28 00:00:00

abstract：:Nano/microfibrous structure can induce high cellular activities because of the topological similarity of the extracellular matrix, and thus, are widely used in various tissue regenerative materials. However, the fabrication of a bioceramic (high weight percent)-based 3D microfibrous structure is extremely difficult be...

journal_title：Scientific reports

authors： Kim M,Yun HS,Kim GH

更新日期：2017-06-09 00:00:00

abstract：:Production of reactive nitrogen species (NO) is a key step in the immune response following infections. NO induces lesions to bacterial DNA, thus limiting bacterial growth within hosts. Using two pathogenic bacteria, Bacillus cereus and Shigella flexneri, we show that the DNA-repair protein Mfd (Mutation-Frequency-Dec...

journal_title：Scientific reports

authors： Guillemet E,Leréec A,Tran SL,Royer C,Barbosa I,Sansonetti P,Lereclus D,Ramarao N

更新日期：2016-07-20 00:00:00

abstract：:Lactobacillus species are the predominant vaginal microbiota found in healthy women of reproductive age and help to prevent pathogen infection by producing lactic acid, H2O2 and anti-microbial compounds. Identification of novel vaginal Lactobacillus isolates that exhibit efficient colonisation and secrete anti-Candida...

journal_title：Scientific reports

authors： Jang SJ,Lee K,Kwon B,You HJ,Ko G

更新日期：2019-05-31 00:00:00

abstract：:In this work, four water-soluble polythiophene derivatives (PT, PT-DDA, PT-ADA, and PT-ADA-PPR) with different pendant moieties were synthesized via oxidative copolymerization by FeCl3. By increasing the hydrophobic ability of side chain moieties, there is a gradually blue shift for the maximum absorption wavelength a...

journal_title：Scientific reports

authors： Wang F,Li M,Wang B,Zhang J,Cheng Y,Liu L,Lv F,Wang S

更新日期：2015-01-05 00:00:00

abstract：:Anatase TiO2 nanoparticles with exposed {001} facets were synthesized from Ti powder via a sequential hydrothermal reaction process. At the first-step hydrothermal reaction, H-titanate nanowires were obtained in NaOH solution with Ti powder, and at second-step hydrothermal reaction, anatase TiO2 nanoparticles with exp...

journal_title：Scientific reports

authors： Chu L,Qin Z,Yang J,Li X

更新日期：2015-07-20 00:00:00

abstract：:We herein report the construction of a novel azo-linked conjugated microporous polymers (Ag@AzoTPE-CMP), which possesses permanent porous structure and Ag+ loading up of 7.62% in the skeleton as effective sorption sites. Ag@AzoTPE-CMP shows considerable adsorption capacity of iodine of 202 wt% in iodine vapor at 350 K...

journal_title：Scientific reports

authors： Liu M,Yao C,Liu C,Xu Y

更新日期：2018-09-19 00:00:00

abstract：:Oligomerization of protein into specific quaternary structures plays important biological functions, including regulation of gene expression, enzymes activity, and cell-cell interactions. Here, we report the determination of two crystal structures of the Grimontia hollisae (formally described as Vibrio hollisae) therm...

journal_title：Scientific reports

authors： Wang YK,Huang SC,Chang CY,Huang WT,Liao MJ,Yip BS,Chou FP,Li TT,Wu TK

更新日期：2019-07-08 00:00:00

abstract：:Xenobiotic resistance is commonly found in species with short generation times such as bacteria, annual plants, and insects. Nevertheless, the fundamental evolutionary principles that govern the spread of resistance alleles hold true for species with longer generation times. One such example could occur with sea lampr...

journal_title：Scientific reports

authors： Christie MR,Sepúlveda MS,Dunlop ES

更新日期：2019-12-03 00:00:00

abstract：:A child with Down syndrome, like any other child, may benefit from interacting with memory stimuli, but needs additional support and help. The use of special teaching methods, which add playfulness and use of the computer, can enhance the memory processes of these children. In this work, we present the virtual environ...

journal_title：Scientific reports

authors： da Cruz Netto OL,Rodrigues SCM,de Castro MV,da Silva DP,da Silva RR,de Souza RRB,de Souza AAF,Bissaco MAS

更新日期：2020-02-21 00:00:00