Synthesis and characterization of water-soluble polythiophene derivatives for cell imaging.

abstract：:Synovial fibroblasts (SF) were reported to produce B cell activating factor (BAFF) in response to stimulation with interferon-γ (IFN-γ) or tumor necrosis factor (TNF). However, the influence of these pro-inflammatory cytokines on other receptors/ligands of the TNF superfamily or associated cytokine receptors in SF has...

journal_title：Scientific reports

authors： Lowin T,Anssar TM,Bäuml M,Classen T,Schneider M,Pongratz G

更新日期：2020-01-21 00:00:00

abstract：:Environmental impacts from ecotourism and outdoor recreation activities on terrestrial and aquatic ecosystems are well-reported in the literature, but less is known regarding the impacts of outdoor environmental education activities. Student activity during stream classes may cause substrate disruption and localized i...

journal_title：Scientific reports

authors： Bossley JP,Smiley PC Jr

更新日期：2019-02-05 00:00:00

abstract：:In the current report, we describe the identification of three genetically distinct groups of prophages integrated into three different chromosomal sites of human gut-associated Bifidobacterium breve and Bifidobacterium longum strains. These bifidobacterial prophages are distantly related to temperate actinobacterioph...

journal_title：Scientific reports

authors： Mavrich TN,Casey E,Oliveira J,Bottacini F,James K,Franz CMAP,Lugli GA,Neve H,Ventura M,Hatfull GF,Mahony J,van Sinderen D

更新日期：2018-08-24 00:00:00

abstract：:The ability to arrange cells and/or microparticles into the desired pattern is critical in biological, chemical, and metamaterial studies and other applications. Researchers have developed a variety of patterning techniques, which either have a limited capacity to simultaneously trap massive particles or lack the spat...

journal_title：Scientific reports

authors： Zhang Y,Lei J,Zhang Y,Liu Z,Zhang J,Yang X,Yang J,Yuan L

更新日期：2017-10-30 00:00:00

abstract：:Delivery and expression of recombinant genes, a key methodology for many applications in biological research, remains a challenge especially for mature neurons. Here, we report easy, highly efficient and well tolerated transduction of adult peripheral and central neuronal populations of diverse species in culture usin...

journal_title：Scientific reports

authors： Levin E,Diekmann H,Fischer D

更新日期：2016-12-13 00:00:00

abstract：:Natural sensory signals have nonlinear structures dynamically composed of the carrier frequencies and the variation of the amplitude (i.e., envelope). How the human brain processes the envelope information is still poorly understood, largely due to the conventional analysis failing to quantify it directly. Here, we us...

journal_title：Scientific reports

authors： Nguyen KT,Liang WK,Lee V,Chang WS,Muggleton NG,Yeh JR,Huang NE,Juan CH

更新日期：2019-11-15 00:00:00

abstract：:Biomarkers of Huntington's disease (HD) in cerebrospinal fluid (CSF) could be of value in elucidating the biology of this genetic neurodegenerative disease, as well as in the development of novel therapeutics. Deranged synaptic and immune function have been reported in HD, and concentrations of the synaptic protein ne...

journal_title：Scientific reports

authors： Byrne LM,Rodrigues FB,Johnson EB,De Vita E,Blennow K,Scahill R,Zetterberg H,Heslegrave A,Wild EJ

更新日期：2018-03-09 00:00:00

abstract：:Cerebral malaria (CM), a complication of malaria infection, is the cause of the majority of malaria-associated deaths in African children. The standard clinical case definition for CM misclassifies ~25% of patients, but when malarial retinopathy (MR) is added to the clinical case definition, the specificity improves f...

journal_title：Scientific reports

authors： Joshi V,Agurto C,Barriga S,Nemeth S,Soliz P,MacCormick IJ,Lewallen S,Taylor TE,Harding SP

更新日期：2017-02-15 00:00:00

abstract：:Prostate cancer is the most commonly diagnosed cancer in men with African American men disproportionally suffering from the burden of this disease. Biomarkers that could discriminate indolent from aggressive and drug resistance disease are lacking. MicroRNAs are small non-coding RNAs that affect numerous physiological...

journal_title：Scientific reports

authors： Cagle P,Niture S,Srivastava A,Ramalinga M,Aqeel R,Rios-Colon L,Chimeh U,Suy S,Collins SP,Dahiya R,Kumar D

更新日期：2019-07-05 00:00:00

abstract：:Petunia × hybrida cv 'Mitchell Diploid' floral volatile benzenoid/phenylpropanoid (FVBP) biosynthesis ultimately produces floral volatiles derived sequentially from phenylalanine, cinnamic acid, and p-coumaric acid. In an attempt to better understand biochemical steps after p-coumaric acid production, we cloned and ch...

journal_title：Scientific reports

authors： Kim JY,Swanson RT,Alvarez MI,Johnson TS,Cho KH,Clark DG,Colquhoun TA

更新日期：2019-06-20 00:00:00

abstract：:The relationship between cumulative exposure to resting heart rate (cumRHR) and mortality remain unclear in the general population. In the Kailuan cohort study, resting heart rate (RHR) was repeatedly measured at baseline and at years 2 and 4 by electrocardiogram among 47,311 adults aged 48.70 ± 11.68. The cumRHR was ...

journal_title：Scientific reports

authors： Zhao Q,Li H,Wang A,Guo J,Yu J,Luo Y,Chen S,Tao L,Li Y,Li A,Guo X,Wu S

更新日期：2017-01-09 00:00:00

abstract：:Excessive Zn2+ causes brain damage via promoting ROS generation. Here we investigated the role of ROS-sensitive TRPM2 channel in H2O2/Zn2+-induced Ca2+ signalling and cell death in microglial cells. H2O2/Zn2+ induced concentration-dependent increases in cytosolic Ca2+ concentration ([Ca2+]c), which was inhibited by PJ...

journal_title：Scientific reports

authors： Mortadza SS,Sim JA,Stacey M,Jiang LH

更新日期：2017-03-21 00:00:00

abstract：:Memristors, memcapacitors, and meminductors represent an innovative generation of circuit elements whose properties depend on the state and history of the system. The hysteretic behavior of one of their constituent variables, is their distinctive fingerprint. This feature endows them with the ability to store and proc...

journal_title：Scientific reports

authors： Guarcello C,Solinas P,Di Ventra M,Giazotto F

更新日期：2017-04-24 00:00:00

abstract：:Nutrient resorption processes in the plants infected by pathogen remain poorly understood. Huanglongbing (HLB) is a destructive disease of citrus. HLB-pathogen 'Candidatus Liberibacter asiaticus' grows specifically in the phloem of hosts and may cause problems in the plant vascular system after infection. Therefore, i...

journal_title：Scientific reports

authors： Cao J,Cheng C,Yang J,Wang Q

更新日期：2015-09-30 00:00:00

abstract：:Seeing with two eyes usually helps one respond faster. Here we show that with ambiguous stimuli, binocular viewing can paradoxically slow down reaction time. This is explained by the observers basing their decision on a noisy neuronal representation within the visual system, with the added noise breaking the symmetry ...

journal_title：Scientific reports

authors： Yehezkel O,Sterkin A,Sagi D,Polat U

更新日期：2015-11-18 00:00:00

abstract：:HSV-2 is one of the most common sexually transmitted pathogens worldwide and HSV-2 infection triggers cytokine and chemokine production. However, little is known about which HSV-2 genes engage in the regulation of NF-κB signaling and what mechanisms are involved. In a screen of the unique short (Us) regions of HSV-2, ...

journal_title：Scientific reports

authors： Lu X,Huang C,Zhang Y,Lin Y,Wang X,Li Q,Liu S,Tang J,Zhou L

更新日期：2017-08-21 00:00:00

abstract：:Ebola virus disease (EVD) is a contagious, severe and often lethal form of hemorrhagic fever in humans. The association of EVD outbreaks with forest clearance has been suggested previously but many aspects remained uncharacterized. We used remote sensing techniques to investigate the association between deforestation ...

journal_title：Scientific reports

authors： Olivero J,Fa JE,Real R,Márquez AL,Farfán MA,Vargas JM,Gaveau D,Salim MA,Park D,Suter J,King S,Leendertz SA,Sheil D,Nasi R

更新日期：2017-10-30 00:00:00

abstract：:Bose Einstein condensates of spin-1 atoms are known to exist in two different phases, both having spontaneously broken spin-rotation symmetry, a ferromagnetic and a polar condensate. Here we show that in two spatial dimensions it is possible to achieve a quantum phase transition from a polar condensate into a singlet ...

journal_title：Scientific reports

authors： Chudnovskiy AL,Cheianov V

更新日期：2018-08-20 00:00:00

abstract：:Pluripotent stem cells (PSCs) have various degrees of pluripotency, which necessitates selection of PSCs with high pluripotency before their application to regenerative medicine. However, the quality control processes for PSCs are costly and time-consuming, and it is essential to develop inexpensive and less laborious...

journal_title：Scientific reports

authors： Nishimura K,Ishiwata H,Sakuragi Y,Hayashi Y,Fukuda A,Hisatake K

更新日期：2019-02-11 00:00:00

abstract：:Electromyography (EMG) is the standard technology for monitoring muscle activity in laboratory environments, either using surface electrodes or fine wire electrodes inserted into the muscle. Due to limitations such as cost, complexity, and technical factors, including skin impedance with surface EMG and the invasive n...

journal_title：Scientific reports

authors： Woodward RB,Stokes MJ,Shefelbine SJ,Vaidyanathan R

更新日期：2019-04-03 00:00:00

abstract：:Reducing macrophage recruitment by silencing chemokine (C-C motif) receptor 2 (CCR2) expression is a promising therapeutic approach against atherosclerosis. However the transfection of macrophages with siRNA is often technically challenging. EGFP-EGF1-conjugated poly (lactic-co-glycolic acid) (PLGA) nanoparticles (ENP...

journal_title：Scientific reports

authors： Wu Z,Chen C,Luo J,Davis JRJ,Zhang B,Tang L,Shi W,Liao D

更新日期：2020-11-12 00:00:00

abstract：:Mustard aphid, also known as turnip aphid (Lipaphis erysimi) is a major insect pest of rapeseed-mustard group of crops. Tremendous economic significance has led to substantial basic research involving gene-expression studies in this insect species. In qRT-PCR analysis of gene-expression, normalization of data against ...

journal_title：Scientific reports

authors： Koramutla MK,Aminedi R,Bhattacharya R

更新日期：2016-05-11 00:00:00

abstract：:Obesity causes low-grade inflammation that is involved in male infertility. Interleukin 1 beta (IL1β) plays an important role in this process. A high-fat diet (HFD) is the most common cause of obesity. However, the effect of a HFD on IL1β and its consequence in reproduction remain unclear. We established a HFD model i...

journal_title：Scientific reports

authors： Zhang J,Li K,Yuan M,Zhang J,Huang G,Ao J,Tan H,Li Y,Gong D,Li J,Kang L,An N,Li F,Lin P,Huang L

更新日期：2017-04-03 00:00:00

abstract：:Focusing on the chemical basis of dietary selection while investigating the nutritional ecology of animals helps understand their feeding biology. It is also important to consider food abundance/biomass while studying the mechanism of animal food selection. We studied leaf selection in two Bornean folivorous primates ...

journal_title：Scientific reports

authors： Matsuda I,Tuuga A,Bernard H,Sugau J,Hanya G

更新日期：2013-01-01 00:00:00

abstract：:It is of paramount importance to improve the control over large area growth of high quality molybdenum disulfide (MoS2) and other types of 2D dichalcogenides. Such atomically thin materials have great potential for use in electronics, and are thought to make possible the first real applications of spintronics. Here in...

journal_title：Scientific reports

authors： Ionescu R,Campbell B,Wu R,Aytan E,Patalano A,Ruiz I,Howell SW,McDonald AE,Beechem TE,Mkhoyan KA,Ozkan M,Ozkan CS

更新日期：2017-07-25 00:00:00

abstract：:Various nickel and magnesium dual-doped LiNixMg0.08Mn1.92-xO4 (x ≤ 0.15) were synthesized via a modified solid-state combustion method. All as-prepared samples show typical spinel phase with a well-defined polyhedron morphology. The Ni-Mg dual-doping obviously decreases the lattice parameter that gives rise to the lat...

journal_title：Scientific reports

authors： Yu Y,Guo J,Xiang M,Su C,Liu X,Bai H,Bai W,Duan K

更新日期：2019-11-14 00:00:00

abstract：:Lipomas are benign fatty tumors with a high prevalence rate, mostly found in adults but have a good prognosis. Until now, reason for lipoma occurrence not been identified. We performed whole exome sequencing to define the mutational spectrum in ten lipoma patients along with their matching control samples. We presente...

journal_title：Scientific reports

authors： Kanojia D,Dakle P,Mayakonda A,Parameswaran R,Puhaindran ME,Min VLK,Madan V,Koeffler P

更新日期：2019-10-07 00:00:00

abstract：:Bradysia odoriphaga and Bradysia difformis are devastating pests of vegetable, ornamental crops and edible mushrooms causing significant losses. Temperature may be an important factor restricting their population abundance in the summer. To determine the effects of short-term heat shock on adults, their survival, long...

journal_title：Scientific reports

authors： Zhu G,Xue M,Luo Y,Ji G,Liu F,Zhao H,Sun X

更新日期：2017-10-17 00:00:00

abstract：:Ataxia-telangiectasia (AT) and related disorders feature cancer predisposition, neurodegeneration, and immunodeficiency resulting from failure to respond to DNA damage. Hypomorphic mutations in MRE11 cause an AT-like disorder (ATLD) with variable clinical presentation. We have sought to understand how diverse MRE11 mu...

journal_title：Scientific reports

authors： Hartlerode AJ,Regal JA,Ferguson DO

更新日期：2018-07-04 00:00:00

abstract：:The accumulation of single nucleotide polymorphisms (SNPs) in the displacement loop (D-loop) of mitochondrial DNA (mtDNA) has been described in various types of cancers, and their association with cancer risk and disease outcome has been extensively identified. In the present study, we investigated the association bet...

journal_title：Scientific reports

authors： Xu J,Guo Z,Zhang J,Cui L,Zhang S,Bai Y

更新日期：2013-01-01 00:00:00