Highly Stable Nanocontainer of APTES-Anchored Layered Titanate Nanosheet for Reliable Protection/Recovery of Nucleic Acid.

Abstract:

:A universal technology for the encapsulative protection of unstable anionic species by highly stable layered metal oxide has been developed via the surface modification of a metal oxide nanosheet. The surface anchoring of (3-aminopropyl)triethoxysilane (APTES) on exfoliated titanate nanosheet yields a novel cationic metal oxide nanosheet, which can be universally used for the hybridization with various biological and inorganic anions. The encapsulation of deoxyribonucleic acid (DNA) in the cationic APTES-anchored titanate lattice makes possible the reliable long-term protection of DNA against enzymatic, chemical, and UV-vis light corrosions. The encapsulated DNA can be easily released from the titanate lattice via sonication, underscoring the functionality of the cationic APTES-anchored titanate nanosheet as a stable nanocontainer for DNA. The APTES-anchored titanate nanosheet can be also used as an efficient CO2 adsorbent and a versatile host material for various inorganic anions like polyoxometalates, leading to the synthesis of novel intercalative nanohybrids with unexplored properties and useful functionalities.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Kim TW,Kim IY,Park DH,Choy JH,Hwang SJ

doi

10.1038/srep21993

subject

Has Abstract

pub_date

2016-02-24 00:00:00

pages

21993

issn

2045-2322

pii

srep21993

journal_volume

6

pub_type

杂志文章
  • Pre-transplant depression decreased overall survival of patients receiving allogeneic hematopoietic stem cell transplantation: a nationwide cohort study.

    abstract::Studies investigating association of depression with overall survival (OS) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) yielded conflicting results. A nationwide cohort study, which included all adult patients [n = 7,170; depression group, 13.3% (N = 956); non-depression group, 86.7% (N = 6,214...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-71208-2

    authors: Wang SM,Park SS,Park SH,Kim NY,Kang DW,Na HR,Lee JW,Han S,Lim HK

    更新日期:2020-09-17 00:00:00

  • Identifying threshold sizes for enlarged abdominal lymph nodes in different age ranges from about 200,000 individual's data.

    abstract::The threshold size for enlarged abdominal lymph nodes (E-ALNs), a common pediatric disorder, has yet to be standardized. According to the maximum short-axis diameter, this study divided ALNs into Grade A (≥ 10 mm), Grade B (8-10 mm), Grade C (5-8 mm), and Grade D (< 5 mm, normal). To identify the threshold size for E-...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-021-81339-9

    authors: He L,Sun Y,Huang G

    更新日期:2021-01-19 00:00:00

  • Hydrogen sulfide modulates actin-dependent auxin transport via regulating ABPs results in changing of root development in Arabidopsis.

    abstract::Hydrogen sulfide (H2S) signaling has been considered a key regulator of plant developmental processes and defenses. In this study, we demonstrate that high levels of H2S inhibit auxin transport and lead to alterations in root system development. H2S inhibits auxin transport by altering the polar subcellular distributi...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep08251

    authors: Jia H,Hu Y,Fan T,Li J

    更新日期:2015-02-05 00:00:00

  • Printable Highly Stable and Superfast Humidity Sensor Based on Two Dimensional Molybdenum Diselenide.

    abstract::Transition metal dichalcogenides (TMDCs) are promising materials for sensing applications, due to their exceptional high performance in nano-electronics. Inherentely, the chemical and thermal responses of TMDCs are highly stable, hence, they pave way for real time sensor applications. This article proposes inceptively...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-62397-x

    authors: Awais M,Khan MU,Hassan A,Bae J,Chattha TE

    更新日期:2020-03-26 00:00:00

  • Light guiding and switching using eccentric core-shell geometries.

    abstract::High Refractive Index (HRI) dielectric nanoparticles have been proposed as an alternative to metallic ones due to their low absorption and magnetodielectric response in the VIS and NIR ranges. For the latter, important scattering directionality effects can be obtained. Also, systems constituted by dimers of HRI dielec...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-11401-y

    authors: Barreda ÁI,Gutiérrez Y,Sanz JM,González F,Moreno F

    更新日期:2017-09-11 00:00:00

  • Comparison of three-dimensional soft-tissue evaluations between skeletal and pseudo-class III malocclusions.

    abstract::The aim of our study was to compare soft tissue measurements with 3D imaging methods in individuals with untreated skeletal and pseudo-Class III malocclusions. The study sample consisted of 75 patients (38 males, 37 females, mean age 12.41 ± 2.35 years) with pseudo- and true skeletal Class III malocclusions and skelet...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-71772-7

    authors: Kale B,Buyukcavus MH

    更新日期:2020-09-07 00:00:00

  • Full left ventricular coverage is essential for the accurate quantification of the area-at-risk by T1 and T2 mapping.

    abstract::T2-weighted cardiovascular magnetic resonance (CMR) using a 3-slice approach has been shown to accurately quantify the edema-based area-at-risk (AAR) in ST-segment elevation myocardial infarction (STEMI). We aimed to compare the performance of a 3-slice approach to full left ventricular (LV) coverage for the AAR by T1...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-05127-0

    authors: Bulluck H,Bryant JA,Lim MX,Tan XW,Ramlall M,Francis R,Kotecha T,Cabrera-Fuentes HA,Knight DS,Fontana M,Moon JC,Hausenloy DJ

    更新日期:2017-07-07 00:00:00

  • Characterization of the electrical conductivity of bone and its correlation to osseous structure.

    abstract::The interaction of osseous tissue with electric fields is an important subject. The electrical stimulation of bone promotes osteogenesis, while bone impedance has been proposed as a measure of osteoporosis, to follow fracture healing, or as a method to improve safety of surgical procedures. However, a deeper understan...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-26836-0

    authors: Balmer TW,Vesztergom S,Broekmann P,Stahel A,Büchler P

    更新日期:2018-06-05 00:00:00

  • Towards Enhanced Performance Thin-film Composite Membranes via Surface Plasma Modification.

    abstract::Advancing the design of thin-film composite membrane surfaces is one of the most promising pathways to deal with treating varying water qualities and increase their long-term stability and permeability. Although plasma technologies have been explored for surface modification of bulk micro and ultrafiltration membrane ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep29206

    authors: Reis R,Dumée LF,Tardy BL,Dagastine R,Orbell JD,Schutz JA,Duke MC

    更新日期:2016-07-01 00:00:00

  • Intranasally administered in situ gelling nanocomposite system of dimenhydrinate: preparation, characterization and pharmacodynamic applicability in chemotherapy induced emesis model.

    abstract::The aim of the current manuscript was to test the applicability of a nanocomposite system of penetration enhancer vesicles (PEVs) within polymeric in situ forming gel network composed of poloxamer and hyaluronic acid for the intranasal delivery of the antiemetic dimenhydrinate (DMH). PEVs were prepared using phospholi...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-10032-7

    authors: Barakat SS,Nasr M,Ahmed RF,Badawy SS,Mansour S

    更新日期:2017-08-30 00:00:00

  • Characterizing the type 2 diabetes mellitus epidemic in Jordan up to 2050.

    abstract::We aimed to characterize the type 2 diabetes mellitus (T2DM) epidemic and the role of key risk factors in Jordan between 1990-2050, and to forecast the T2DM-related costs. A recently-developed population-level T2DM mathematical model was adapted and applied to Jordan. The model was fitted to six population-based surve...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-77970-7

    authors: Awad SF,Huangfu P,Dargham SR,Ajlouni K,Batieha A,Khader YS,Critchley JA,Abu-Raddad LJ

    更新日期:2020-12-03 00:00:00

  • Oxidative status and intestinal health of gilthead sea bream (Sparus aurata) juveniles fed diets with different ARA/EPA/DHA ratios.

    abstract::The present work assessed the effects of dietary ratios of essential fatty acids, arachidonic (ARA), eicosapentaenoic (EPA) and docosahexaenoic acid (DHA), on liver and intestine oxidative status, intestinal histomorphology and gut microbiota of gilthead sea bream. Four isoproteic and isolipidic plant-based diets were...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-70716-5

    authors: Magalhães R,Guerreiro I,Santos RA,Coutinho F,Couto A,Serra CR,Olsen RE,Peres H,Oliva-Teles A

    更新日期:2020-08-14 00:00:00

  • Current controlled switching of impedance in magnetic conductor with tilted anisotropy easy axis and its applications.

    abstract::We present a concept and prototype of a memory element based on current driven magneto-impedance (MI) effect that stores the binary data (0, 1) as the orientation of the magnetization. The magnetization orientation in the surface layer with tilted anisotropy easy axis can be switched controllably between two stable st...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep36180

    authors: Ipatov M,Zhukova V,Zhukov A,Gonzalez J

    更新日期:2016-10-26 00:00:00

  • Is there a close association of depression with either constipation or dysosmia in Parkinson's disease?

    abstract::A possible association between depression and either the severity of constipation or dysosmia in Parkinson's disease (PD) patients was investigated in this cross-sectional study. One-hundred six patients who had the history of PD for less than 5 years were recruited. Depression was measured using the Beck Depression I...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-72381-0

    authors: Chang TY,Chen YH,Chang MH,Lin CH

    更新日期:2020-09-23 00:00:00

  • Cisplatin bioconjugated enzymatic GNPs amplify the effect of cisplatin with acquiescence.

    abstract::Enzymatic gold nanoparticles (B-GNPs) have been synthesized using a natural anticancer agent bromelain (a cysteine protease) and these nanoparticles were used to bioconjugate Cisplatin (highly effective against osteosarcoma and lung cancer). Cisplatin bioconjugated bromelain encapsulated gold nanoparticles (B-C-GNPs) ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-50215-y

    authors: Iram S,Zahera M,Wahid I,Baker A,Raish M,Khan A,Ali N,Ahmad S,Khan MS

    更新日期:2019-09-25 00:00:00

  • Machine learning plus optical flow: a simple and sensitive method to detect cardioactive drugs.

    abstract::Current preclinical screening methods do not adequately detect cardiotoxicity. Using human induced pluripotent stem cell-derived cardiomyocytes (iPS-CMs), more physiologically relevant preclinical or patient-specific screening to detect potential cardiotoxic effects of drug candidates may be possible. However, one of ...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep11817

    authors: Lee EK,Kurokawa YK,Tu R,George SC,Khine M

    更新日期:2015-07-03 00:00:00

  • Predicting global invasion risks: a management tool to prevent future introductions.

    abstract::Predicting regions at risk from introductions of non-native species and the subsequent invasions is a fundamental aspect of horizon scanning activities that enable the development of more effective preventative actions and planning of management measures. The Asian cyprinid fish topmouth gudgeon Pseudorasbora parva ha...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep26316

    authors: Fletcher DH,Gillingham PK,Britton JR,Blanchet S,Gozlan RE

    更新日期:2016-05-20 00:00:00

  • Long non-coding RNA PARTICLE bridges histone and DNA methylation.

    abstract::PARTICLE (Gene PARTICL- 'Promoter of MAT2A-Antisense RadiaTion Induced Circulating LncRNA) expression is transiently elevated following low dose irradiation typically encountered in the workplace and from natural sources. This long non-coding RNA recruits epigenetic silencers for cis-acting repression of its neighbour...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-017-01875-1

    authors: O'Leary VB,Hain S,Maugg D,Smida J,Azimzadeh O,Tapio S,Ovsepian SV,Atkinson MJ

    更新日期:2017-05-11 00:00:00

  • Optically Transparent Ferromagnetic Nanogranular Films with Tunable Transmittance.

    abstract::Developing optically transparent magnets at room temperature is an important challenge. They would bring many innovations to various industries, not only for electronic and magnetic devices but also for optical applications. Here we introduce FeCo-(Al-fluoride) nanogranular films exhibiting ferromagnetic properties wi...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep34227

    authors: Kobayashi N,Masumoto H,Takahashi S,Maekawa S

    更新日期:2016-09-28 00:00:00

  • Utilization of (134)Cs/(137)Cs in the environment to identify the reactor units that caused atmospheric releases during the Fukushima Daiichi accident.

    abstract::The Fukushima Daiichi nuclear power reactor units that generated large amounts of airborne discharges during the period of March 12-21, 2011 were identified individually by analyzing the combination of measured (134)Cs/(137)Cs depositions on ground surfaces and atmospheric transport and deposition simulations. Because...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep31376

    authors: Chino M,Terada H,Nagai H,Katata G,Mikami S,Torii T,Saito K,Nishizawa Y

    更新日期:2016-08-22 00:00:00

  • Dissection of Pharmacological Mechanism of Chinese Herbal Medicine Yihuo Huatan Formula on Chronic Obstructive Pulmonary Disease: A Systems Pharmacology-Based Study.

    abstract::Chronic obstructive pulmonary disease (COPD) is one of the most common respiratory diseases. Yihuo Huatan Formula (YHF), as a proven Chinese Herbal Medicine (CHM), has been verified to be effective in the treatment of stable COPD through years' of practice. Nevertheless, its working mechanism is still unclear. We soug...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-50064-9

    authors: Zhang XW,Liu W,Jiang HL,Mao B

    更新日期:2019-09-17 00:00:00

  • Molecular targets for diagnostic and intraoperative imaging of pancreatic ductal adenocarcinoma after neoadjuvant FOLFIRINOX treatment.

    abstract::Neoadjuvant systemic treatment is increasingly being integrated in the standard treatment of pancreatic ductal adenocarcinoma (PDAC) patients to improve oncological outcomes. Current available imaging techniques remain unreliable in assessing response to therapies, as they cannot distinguish between (vital) tumor tiss...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-73242-6

    authors: Vuijk FA,de Muynck LDAN,Franken LC,Busch OR,Wilmink JW,Besselink MG,Bonsing BA,Bhairosingh SS,Kuppen PJK,Mieog JSD,Sier CFM,Vahrmeijer AL,Verheij J,Fariňa-Sarasqueta A,Swijnenburg RJ

    更新日期:2020-10-01 00:00:00

  • Enzyme-based listericidal nanocomposites.

    abstract::Cell lytic enzymes represent an alternative to chemical decontamination or use of antibiotics to kill pathogenic bacteria, such as listeria. A number of phage cell lytic enzymes against listeria have been isolated and possess listericidal activity; however, there has been no attempt to incorporate these enzymes onto s...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep01584

    authors: Solanki K,Grover N,Downs P,Paskaleva EE,Mehta KK,Lee L,Schadler LS,Kane RS,Dordick JS

    更新日期:2013-01-01 00:00:00

  • Frequency and Phase Characteristics of Candle Flame Oscillation.

    abstract::The combustion of candles exhibits a variety of dynamical behaviors. Binding several candles together will result in flickering of candle flames, which is generally described as a nonlinear oscillator. The impact on the frequency of the flame by several factors, such as the arrangement, the number and the asymmetry of...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-018-36754-w

    authors: Chen T,Guo X,Jia J,Xiao J

    更新日期:2019-01-23 00:00:00

  • Skillful statistical models to predict seasonal wind speed and solar radiation in a Yangtze River estuary case study.

    abstract::This paper illustrates the potential for seasonal prediction of wind and solar energy resources through a case study in the Yangtze River estuary. Sea surface temperature and geopotential height-based climate predictors, each with high correlation to ensuing seasonal wind speed and solar radiation at the Baoshan weath...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-65281-w

    authors: Zeng P,Sun X,Farnham DJ

    更新日期:2020-05-25 00:00:00

  • The KDEL trafficking receptor exploits pH to tune the strength of an unusual short hydrogen bond.

    abstract::The endoplasmic reticulum (ER) is the main site of protein synthesis in eukaryotic cells and requires a high concentration of luminal chaperones to function. During protein synthesis, ER luminal chaperones are swept along the secretory pathway and must be retrieved to maintain cell viability. ER protein retrieval is a...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-020-73906-3

    authors: Wu Z,Newstead S,Biggin PC

    更新日期:2020-10-09 00:00:00

  • Isolation, characterization and antifungal docking studies of wortmannin isolated from Penicillium radicum.

    abstract::During the search for a potent antifungal drug, a cell-permeable metabolite was isolated from a soil isolate taxonomically identified as Penicillium radicum. The strain was found to be a potent antifungal agent. Production conditions of the active compound were optimized and the active compound was isolated, purified,...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep11948

    authors: Singh V,Praveen V,Tripathi D,Haque S,Somvanshi P,Katti SB,Tripathi CK

    更新日期:2015-07-10 00:00:00

  • Doxycycline inhibits electric field-induced migration of non-small cell lung cancer (NSCLC) cells.

    abstract::Adenocarcinoma, large cell carcinoma and squamous cell carcinoma are the most commonly diagnosed subtypes of non-small cell lung cancers (NSCLC). Numerous lung cancer cell types have exhibited electrotaxis under direct current electric fields (dcEF). Physiological electric fields (EF) play key roles in cancer cell mig...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-44505-8

    authors: Chang HF,Cheng HT,Chen HY,Yeung WK,Cheng JY

    更新日期:2019-05-30 00:00:00

  • K-space polarimetry of bullseye plasmon antennas.

    abstract::Surface plasmon resonators can drastically redistribute incident light over different output wave vectors and polarizations. This can lead for instance to sub-diffraction sized nanoapertures in metal films that beam and to nanoparticle antennas that enable efficient conversion of photons between spatial modes, or heli...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/srep09966

    authors: Osorio CI,Mohtashami A,Koenderink AF

    更新日期:2015-04-30 00:00:00

  • Role of the membrane potential in mitochondrial protein unfolding and import.

    abstract::Newly synthesized mitochondrial precursor proteins have to become unfolded to cross the mitochondrial membranes. This unfolding is achieved primarily by mitochondrial Hsp70 (mtHsp70) for presequence-containing precursor proteins. However, the membrane potential across the inner membrane (ΔΨ) could also contribute to u...

    journal_title:Scientific reports

    pub_type: 杂志文章

    doi:10.1038/s41598-019-44152-z

    authors: Sato TK,Kawano S,Endo T

    更新日期:2019-05-21 00:00:00