Gene-activated matrix/bone marrow-derived mesenchymal stem cells constructs regenerate sweat glands-like structure in vivo.

abstract：:The aim of this study was to test the hypothesis that duplication/hybridization of functional domains of naturally occurring pellicle peptides amplified the inhibitory effect of hydroxyapatite crystal growth, which is related to enamel remineralization and dental calculus formation. Histatin 3, statherin, their functi...

journal_title：Scientific reports

authors： Valente MT,Moffa EB,Crosara KTB,Xiao Y,de Oliveira TM,Machado MAAM,Siqueira WL

更新日期：2018-02-28 00:00:00

abstract：:Metabolic pathways that are corrupted at early stages of insulin resistance (IR) remain elusive. This study investigates changes in body metabolism in clinically healthy and otherwise asymptomatic subjects that may become apparent already under compromised insulin sensitivity (IS) and prior to IR. 47 clinically health...

journal_title：Scientific reports

authors： Halama A,Suleiman NN,Kulinski M,Bettahi I,Hassoun S,Alkasem M,Abdalhakam I,Iskandarani A,Samra TA,Atkin SL,Suhre K,Abou-Samra AB

更新日期：2020-10-13 00:00:00

abstract：:The use of microwave (MW) irradiation to increase the rate of chemical reactions has attracted much attention recently in nearly all fields of chemistry due to substantial enhancements in reaction rates. However, the intrinsic nature of the effects of MW irradiation on chemical reactions remains unclear. Herein, the h...

journal_title：Scientific reports

authors： Zhou J,Xu W,You Z,Wang Z,Luo Y,Gao L,Yin C,Peng R,Lan L

更新日期：2016-04-27 00:00:00

abstract：:Experiments were conducted to improve jenny conception rates through induced ovulation and timed insemination. Jennies in control, hCG and LH groups were injected intramuscularly with saline alone or saline containing hCG or LH, respectively, when the dominant follicle diameter reached 35 mm. Then, follicle developmen...

journal_title：Scientific reports

authors： Chang ZL,Li BX,Liu B,Yao L,Yu J,Jiang GM,Tan JH

更新日期：2019-03-01 00:00:00

abstract：:The frequency and form of visual signals can be shaped by selection from predators, prey or both. When a signal simultaneously attracts predators and prey selection may favour a strategy that minimizes risks while attracting prey. Accordingly, varying the frequency and form of the silken decorations added to their web...

journal_title：Scientific reports

authors： Yeh CW,Blamires SJ,Liao CP,Tso IM

更新日期：2015-03-30 00:00:00

abstract：:In this study we measured the degrees to which the Schottky barrier heights (SBHs) are lowered in ZnO nanowire (NW) devices under illumination with UV light. We measured the I-V characteristics of ZnO nanowire devices to confirm that ZnO is an n-type semiconductor and that the on/off ratio is approximately 10(4). From...

journal_title：Scientific reports

authors： Lu MY,Lu MP,You SJ,Chen CW,Wang YJ

更新日期：2015-10-12 00:00:00

abstract：:Varroa destructor mites express strong avoidance of the Apis cerana worker brood in the field. The molecular mechanism for this phenomenon remains unknown. We identified a Varroa toxic protein (VTP), which exhibited toxic activity toward A. cerana worker larvae, in the saliva of these mites, and expressed VTP in an Es...

journal_title：Scientific reports

authors： Zhang Y,Han R

更新日期：2018-02-21 00:00:00

abstract：:Real-time Precise Point Positioning (PPP) technique is being widely applied for providing precise positioning services with the significant improvement on satellite precise products accuracy. With the rapid development of the multi-constellation Global Navigation Satellite Systems (multi-GNSS), currently, about 80 nav...

journal_title：Scientific reports

authors： Gao Z,Shen W,Zhang H,Niu X,Ge M

更新日期：2016-07-29 00:00:00

abstract：:Algae-bacteria interaction is one of the main factors underlying the formation of harmful algal blooms (HABs). The aim of this study was to develop a genome-wide high-throughput screening method to identify HAB-influenced specific interactive bacterial metabolites using a comprehensive collection of gene-disrupted E. ...

journal_title：Scientific reports

authors： Heo J,Cho K,Kim U,Cho DH,Ko S,Tran QG,Lee YJ,Ryu CM,Kim HS

更新日期：2020-06-30 00:00:00

abstract：:Doping with the optimum concentration of carriers (electrons or holes) can modify the physical properties of materials. Therefore, improved ways to achieve carrier doping have been pursued extensively for more than 50 years. Metal-intercalation is one of the most important techniques for electron doping of organic / i...

journal_title：Scientific reports

authors： Takahei Y,Tomita K,Itoh Y,Ashida K,Lee JH,Nishimoto N,Kimura T,Kudo K,Nohara M,Kubozono Y,Kambe T

更新日期：2016-01-06 00:00:00

abstract：:We previously identified novel bioactive polysaccharides from Bactrocera cucurbitae and Antheraea yamamai that activate innate immunity in RAW264 murine macrophages. However, in terms of potential applications in the cultivation of prawns, there were problems with the availability of these insects. However, we have no...

journal_title：Scientific reports

authors： Ali MFZ,Yasin IA,Ohta T,Hashizume A,Ido A,Takahashi T,Miura C,Miura T

更新日期：2018-06-11 00:00:00

abstract：:The properties of the human mind affect the quality of scientific knowledge through the insertion of unconscious biases during the research process. These biases frequently cause overestimation of the effects under study, thereby violating the reproducibility of the research and potentially leading to incorrect conclu...

journal_title：Scientific reports

authors： Zvereva EL,Kozlov MV

更新日期：2021-01-08 00:00:00

abstract：:Cerebral aneurysms are abnormal focal dilatations of arterial vessel walls with pathological vessel structure alterations. Sudden rupture can lead to a subarachnoid hemorrhage, which is associated with a high mortality. Therefore, the origin of cerebral aneurysms as well as the progression to the point of rupture need...

journal_title：Scientific reports

authors： Sehm T,Uckermann O,Galli R,Meinhardt M,Rickelt E,Krex D,Schackert G,Kirsch M

更新日期：2020-07-23 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Wang Y,Chen D,He X,Shen J,Xiong M,Wang X,Zhou D,Wei Z

更新日期：2020-02-20 00:00:00

abstract：:DNA double-strand break (DSB) repair is crucial to maintain genomic stability. The fidelity of the repair depends on the complexity of the lesion, with clustered DSBs being more difficult to repair than isolated breaks. Using live cell imaging of heavy ion tracks produced at a high-energy particle accelerator we visua...

journal_title：Scientific reports

authors： Jakob B,Dubiak-Szepietowska M,Janiel E,Schmidt A,Durante M,Taucher-Scholz G

更新日期：2020-01-29 00:00:00

abstract：:Single nucleotide polymorphisms (SNPs) in the 3'-untranslated regions targeted by putative mircoRNA can change its binding strength, affecting the susceptibility and prognosis of cancer. We aimed to investigate the associations between SNPs within miR-148a binding sites and gastric cancer (GC) risk and prognosis. Usin...

journal_title：Scientific reports

authors： Song P,Zhu H,Zhang D,Chu H,Wu D,Kang M,Wang M,Gong W,Zhou J,Zhang Z,Zhao Q

更新日期：2014-11-17 00:00:00

abstract：:Native collagen is arranged in bundles of aligned fibrils to withstand in vivo mechanical loads. Reproducing such a process under in vitro conditions has not met with major success. Our approach has been to induce nanolinks, during the self-assembly process, leading to delayed rather than inhibited fibrillogenesis. Fo...

journal_title：Scientific reports

authors： Nidhin M,Vedhanayagam M,Sangeetha S,Kiran MS,Nazeer SS,Jayasree RS,Sreeram KJ,Nair BU

更新日期：2014-08-06 00:00:00

abstract：:Obesity is highly heritable, but the specific genes influencing obesity related traits are largely unknown. Fibroblast growth factor 2 (FGF2) could influence adipocyte differentiation. However, the association of FGF2 polymorphisms and obesity remains unclear. This study aimed to investigate the associations of both t...

journal_title：Scientific reports

authors： Hao RH,Guo Y,Dong SS,Weng GZ,Yan H,Zhu DL,Chen XF,Chen JB,Yang TL

更新日期：2016-02-16 00:00:00

abstract：:Obesity causes a wide range of systemic diseases and is associated with mood and anxiety disorders. It is also associated with dopaminergic reward system function. However, the relationships between microstructural properties of the dopaminergic system and body mass index (BMI) have not been investigated. In this stud...

journal_title：Scientific reports

authors： Takeuchi H,Taki Y,Nouchi R,Yokoyama R,Nakagawa S,Iizuka K,Sakaki K,Araki T,Nozawa T,Ikeda S,Yokota S,Hanawa S,Magistro D,Kotozaki Y,Sasaki Y,Dos S Kawata KH,Kawashima R

更新日期：2020-07-28 00:00:00

abstract：:Foot-and-mouth disease (FMD) is a highly contagious disease of livestock affecting animal production and trade throughout Asia and Africa. Understanding FMD virus (FMDV) global movements and evolution can help to reconstruct the disease spread between endemic regions and predict the risks of incursion into FMD-free co...

journal_title：Scientific reports

authors： Bachanek-Bankowska K,Di Nardo A,Wadsworth J,Mioulet V,Pezzoni G,Grazioli S,Brocchi E,Kafle SC,Hettiarachchi R,Kumarawadu PL,Eldaghayes IM,Dayhum AS,Meenowa D,Sghaier S,Madani H,Abouchoaib N,Hoang BH,Vu PP,Dukpa K,Gu

更新日期：2018-10-02 00:00:00

abstract：:Emergence of new molecules acting directly on the hepatitic C virus (HCV) has improved treatment outcomes. However, there is a risk of selecting viral escape mutants, so a new combination is needed using different inhibitors that target different steps of the HCV infectious cycle. Novel single tablet formulations were...

journal_title：Scientific reports

authors： Shiha G,Soliman R,Elbasiony M,Darwish NHE,Mousa SA

更新日期：2019-09-19 00:00:00

abstract：:There is a need to develop economical, efficient and widely available therapeutic approaches to enhance the rate of skin wound healing. The optimal outcome of wound healing is restoration to the pre-wound quality of health. In this study we investigate the cellular response to biological stimuli using functionalized n...

journal_title：Scientific reports

authors： Bradshaw M,Ho D,Fear MW,Gelain F,Wood FM,Iyer KS

更新日期：2014-11-11 00:00:00

abstract：:In recent years, macrophages have been shown to be tremendously plastic in both in vitro and in vivo settings; however, it remains unclear whether macrophages retain any persistent memory of past polarization states which may then impact their future repolarization to new states. Here, we perform deep transcriptomic p...

journal_title：Scientific reports

authors： Liu SX,Gustafson HH,Jackson DL,Pun SH,Trapnell C

更新日期：2020-07-23 00:00:00

abstract：:Gamma radiation is a commonly used adjuvant treatment for abdominally localized cancer. Since its therapeutic potential is limited due to gastrointestinal (GI) syndrome, elucidation of the regenerative response following radiation-induced gut injury is needed to develop a preventive treatment. Previously, we showed th...

journal_title：Scientific reports

authors： Orzechowska EJ,Katano T,Bialkowska AB,Yang VW

更新日期：2020-10-27 00:00:00

abstract：:It is well known that supercritical water is a favourable medium for biomass conversion followed by its hydrodeoxygenation (HDO). Moreover, the actual kinetics and mechanism of reaction occurring in the supercritical water are not yet completely understood, either by experimental or computational approaches. Within th...

journal_title：Scientific reports

authors： Agrawal K,Kishore N

更新日期：2020-06-08 00:00:00

abstract：:Cisplatin (CDDP) is potent anticancer agent used for several tumor types. Thymoquinone (TQ) is naturally occurring compound drawing great attention as anticancer and chemomodulator for chemotherapies. Herein, we studied the potential cytotoxicity of thymoquinone, CDDP and their combination against human oral squamous ...

journal_title：Scientific reports

authors： Alaufi OM,Noorwali A,Zahran F,Al-Abd AM,Al-Attas S

更新日期：2017-10-13 00:00:00

abstract：:ES-62 is a secreted parasitic worm-derived immunomodulator that exhibits therapeutic potential in allergy by downregulating aberrant MyD88 signalling to normalise the inflammatory phenotype and mast cell responses. IL-33 plays an important role in driving mast cell responses and promoting type-2 allergic inflammation,...

journal_title：Scientific reports

authors： Ball DH,Al-Riyami L,Harnett W,Harnett MM

更新日期：2018-03-14 00:00:00

abstract：:WRINKLED1 (WRI1), an APETALA2 (AP2)-type transcription factor, has been shown to be required for the regulation of carbon partitioning into fatty acid (FA) synthesis in plant seeds. To our knowledge, the regulatory network of WRI1 remains unknown in Prunus sibirica kernel (PSK), a novel woody biodiesel feedstock in Ch...

journal_title：Scientific reports

authors： Deng S,Mai Y,Shui L,Niu J

更新日期：2019-02-25 00:00:00

abstract：:Visualizing fast micrometer scale internal movements of small animals is a key challenge for functional anatomy, physiology and biomechanics. We combine phase contrast tomographic microscopy (down to 3.3 μm voxel size) with retrospective, projection-based gating (in the order of hundreds of microseconds) to improve th...

journal_title：Scientific reports

authors： Mokso R,Schwyn DA,Walker SM,Doube M,Wicklein M,Müller T,Stampanoni M,Taylor GK,Krapp HG

更新日期：2015-03-12 00:00:00

abstract：:The interplay between the quasi 1-dimensional CuO-chains and the 2-dimensional CuO2 planes of YBa(2)Cu(3)O(6+x) (YBCO) has been in focus for a long time. Although the CuO-chains are known to be important as charge reservoirs that enable superconductivity for a range of oxygen doping levels in YBCO, the understanding o...

journal_title：Scientific reports

authors： Magnuson M,Schmitt T,Strocov VN,Schlappa J,Kalabukhov AS,Duda LC

更新日期：2014-11-12 00:00:00